Category: 3818-50-6

Zhuang, Yaping published the artcileSystemic analysis of 150 kinds of tablet, Synthetic Route of 3818-50-6, the publication is Yaoxue Tongbao (1982), 17(6), 332-5, database is CAplus.

Marquis reagent, modified Dragendorff reagent, Folin reagent, ammonium vanadate-H₂SO₄ reagent, Ehrlich’s reagent, Froehde reagent and 8 other test reagents were used in the identification of âˆ?50 different tablets.

Yaoxue Tongbao published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C14H14O5S, Synthetic Route of 3818-50-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Rongchang published the artcileOscillographic titration with sodium tetraphenylboron for pharmaceutical and metallurgical analyses, Computed Properties of 3818-50-6, the publication is Fenxi Ceshi Xuebao (2002), 21(2), 39-41, database is CAplus.

An oscillog. titrimetric method with sodium tetraphenylboron was described for pharmaceutical and metallurgical analyses. Since the proposed method was based on the visual display of a sharp oscillog. end-point and was not affected by the colors of the solution, precipitate and excipient, it can be used to replace gravimetric anal., non-aqueous titration, and extraction-photometric anal. The method was used in the determination of alkaloid and quaternary ammonium salt with the RSD 0.03-0.06% and the results consistent with those obtained by pharmacopoeia method. Some metallurgical samples were determined with the RSD 0.15- 0.40%, the recovery 98.7-100% and the results consistent with those obtained by standard method. The method was accurate, rapid, simple and cheap, and hence had large potential for extensive application.

Fenxi Ceshi Xuebao published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C7H11N, Computed Properties of 3818-50-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kochansky, Jan published the artcileScreening additional antibiotics for efficacy against American foulbrood, Category: alcohols-buliding-blocks, the publication is Journal of Apicultural Research (2005), 44(1), 24-28, database is CAplus.

The sensitivity of Paenibacillus larvae larvae (American foulbrood, AFB) to 35 antibiotics and synthetic antimicrobials, including two previously reported, was investigated. All compounds but one are currently approved by the US Food and Drug Administration for agricultural uses. The most active approved antibiotics screened were pirlimycin, tiamulin, and the polyether ionophores, particularly narasin, lasalocid, salinomycin, laidlomycin, and maduramicin. Pirlimycin and tiamulin show high activity in vitro, but share the mode of action of tylosin and lincomycin (inhibition of ribosomal peptide synthesis), and therefore have no advantage over it. While the ionophores have high in vitro activity and a completely different mode of action (interference with cation transport across cell membranes) and therefore seemed to represent potential alternative treatments for AFB, they were inactive in the field.

Journal of Apicultural Research published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C28H29NO4, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Gershbein, Leon L. published the artcileAction of drugs and chemical agents on rat liver regeneration, Recommanded Product: N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, the publication is Drug and Chemical Toxicology (1977) (1985), 8(3), 125-43, database is CAplus and MEDLINE.

A large number (> 270) of drugs, chems., and other agents were tested for their effects on the regeneration of liver in hepatectomized rats. Seven anticonvulsants, 4 antiinflammatory drugs, 4 sedatives-hypnotics, the antipyretic-analgesic aminopyrine  [58-15-1], the antifungal griseofulvin  [126-07-8], a uricosuric, a muscle relaxant, a hydrocholeretic, an antihypertensive, and a thyroid inhibitor were hepatotrophic. Most the remaining drugs were inactive in this screening, whereas a few suppressed liver regeneration.

Drug and Chemical Toxicology (1977) published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C28H29NO4, Recommanded Product: N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Shiraki, Tadashi published the artcileMass treatment of trichuriasis with several anthelmintics, especially on the statistical criteria for the evaluation of egg-diminishing effects of the drug, Product Details of C28H29NO4, the publication is Acta Medica et Biologica (Niigata, Japan) (1973), 21(1), 11-27, database is CAplus.

A single oral dose of paromomycin sulfate [1263-89-4] (3g), tetrachlorethylene [127-18-4] (1.5 g), bithional [97-18-7] (1.5 g), biphenium hydroxynaphthoate [3818-50-6] (1.4 g), 1-bromo-2-naphthol [573-97-7] (4 g), piperazine [110-85-0] (3 g), and a santonin-kainic acid mixture [51990-05-7] (50 mg-5 mg) given to whipworm (Trichuris trichiura) infested school children gave a 60.0, 52.6, 42.9, 42.9, 33.4, 28.6, and 0% decrease, resp., in the number of eggs in stool samples. Tetrachloroethylene and 1-bromo-2-naphthol completely eliminated eggs from, respectively, 26.3 and 16.7% of the children treated.

Acta Medica et Biologica (Niigata, Japan) published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C4H4N2O2, Product Details of C28H29NO4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Blagov, N. A. published the artcileMorphological changes in the gastric and intestinal mucosa after mebendazole treatment of rats, Application of N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, the publication is Meditsinskaya Parazitologiya i Parazitarnye Bolezni (1991), 41-4, database is CAplus and MEDLINE.

The effect of mebendazole on the gastric and intestinal mucosa was studied in intact white rats. The drug caused significant damage to the mucosa, especially to goblet cells of villi and crypts and interfered with mucoid secretion. The alterations after mebendazole administration were more severe than those caused by naphthamon. On the 13-15th day after treatment, a complete restoration of the damage was not yet seen.

Meditsinskaya Parazitologiya i Parazitarnye Bolezni published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C28H29NO4, Application of N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Hermoso, R. published the artcileSurvival study of parasitic helminths. III. Effects of antihelminthic and other drugs on survival of Ascaris lumbricoides, Recommanded Product: N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, the publication is Revista Iberica de Parasitologia (1970), 30(4), 567-85, database is CAplus.

The metabolism of A. lumbricoides from pigs was studied in media with the addition of anthelmintics and other drugs; intake of glucose, NH3 production, dry residue, and final glycogen were also determined The action of these substances was observed on the worm’s mobility, the elapsed time until inhibition, and recuperation (if any). Santonin, dimethoate, Sevin, piperazine, NaF, bephenium, hydroxynaphthoate, pyrvinium pamoate, arecoline bromide, hexylresorcinol, dithiazanine iodide, and dithiocarbo(bisethylenediamine) totally inhibited Ascaris activity. Naphthalophos, thiabendazole, phenothiazine, diethylcarbamazine, and Na N1-(2-quinoxalinyl)sulfanilamide partially inhibited muscular activity.

Revista Iberica de Parasitologia published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C28H29NO4, Recommanded Product: N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Daldrup, T. published the artcileA screening test for pharmaceuticals, drugs and insecticides with reversed-phase liquid chromatography – retention data of 560 compounds, Application of N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, the publication is Chromatography Newsletter (1982), 10(1), 1-7, database is CAplus.

High-performance reversed-phase liquid chromatog. retention data are given. The relative retention times were calculated as the ratio of retention times of compound and reference compound 5-(p-methylphenyl)-5-phenylhydantoin. The UV detector wavelength was 220 nm, where most of the compounds gave a good response. The sensitivity of the method for each compound is rated from very good to bad. Two solvent programs and a prepacked column C-18 SIL-X-10 were used for the anal.

Chromatography Newsletter published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C28H29NO4, Application of N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Shkodin, N. E. published the artcileTesting of anthelmintics during experimental and spontaneous nematodosis of sheep, Quality Control of 3818-50-6, the publication is Trudy Kirgizskogo Nauchno-Issledovatel’skogo Instituta Zhivotnovodstva i Veterinarii (1975), 20-1, database is CAplus.

Nephthamon (I) [3818-50-6] (0.5 g/kg) or copper sodium carbonatoarsenate [65722-74-9] (0.1 g/kg) given orally to sheep exptl. infested with lung nematodes daily for 6 days gave complete control of the parasites. I also gave 100% control in spontaneously infested sheep, whereas Cu Na carbonatoarsenate was about 95% effective.

Trudy Kirgizskogo Nauchno-Issledovatel’skogo Instituta Zhivotnovodstva i Veterinarii published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C12H16O3, Quality Control of 3818-50-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zasosov, R. V. published the artcileExcretion of naphthamon in the bile of white rats, Recommanded Product: N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, the publication is Meditsinskaya Parazitologiya i Parazitarnye Bolezni (1973), 42(5), 557-60, database is CAplus and MEDLINE.

Naphthamon (I) [3818-50-6] (50-1250 mg/kg) was detected in the bile 10 min after it was introduced into the duodenum of rats. The total amount of I excreted in the bile for 24-48 hr was <1% of the dose applied.

Meditsinskaya Parazitologiya i Parazitarnye Bolezni published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C5H11BrO, Recommanded Product: N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts