Category: 34957-73-8

New downstream synthetic route of Methyl 9-hydroxynonanoate

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,34957-73-8, its application will become more common.

Electric Literature of 34957-73-8, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 34957-73-8 as follows.

Step 2; 9-Oxo-nonanoic acid methyl ester; To a solution of 5.2 g (28 mmol) 9-Hydroxy-nonanoic acid methyl ester in 350 mL DCM is added 9.1 g (41 mmol) Pyridinium chlorochromate and the reaction is stirred for 15 h at rt. The reaction is diluted with DCM, silica is added, the mixture is filtered through a pad of Hyflo and thoroughly washed with DCM. The solvent is removed in vacuo to give the title compound as a green oil, which is used without further purification. MS (method D): 204 [M+H2O]

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,34957-73-8, its application will become more common.

Reference:
Patent; NOVARTIS AG; WO2008/101665; (2008); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple exploration of 34957-73-8

Statistics shows that 34957-73-8 is playing an increasingly important role. we look forward to future research findings about Methyl 9-hydroxynonanoate.

Reference of 34957-73-8, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.34957-73-8, name is Methyl 9-hydroxynonanoate, molecular formula is C10H20O3, molecular weight is 188.26, as common compound, the synthetic route is as follows.

Methyl 9-hydroxydecanoate (37.6 g, 0.2 mol) and MnO2 (17.4 g, 0.2 mol) were placed in a reaction kettle, 200 ml of ethyl acetate was added, stirring was started, 180 rpm, temperature 50 ° C, real-time monitoring The reaction was carried out, and after 8 h, it was cooled to room temperature, filtered, and the solvent was evaporated under reduced pressure to give 35.3 g of white solid product

Statistics shows that 34957-73-8 is playing an increasingly important role. we look forward to future research findings about Methyl 9-hydroxynonanoate.

Reference:
Patent; Beijing Xuyang Technology Co., Ltd.; Gao Xingdong; Du Chunhua; Pan Xiaojun; Wang Penghui; (11 pag.)CN109593045; (2019); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts