Category: 329735-68-4

SDS of cas: 329735-68-4On November 15, 2001 ,《Phosphonites Based on the Paracyclophane Backbone: New Ligands for Highly Selective Rhodium-Catalyzed Asymmetric Hydrogenation》 appeared in Organic Letters. The author of the article were Zanotti-Gerosa, Antonio; Malan, Christophe; Herzberg, Daniela. The article conveys some information:

The synthesis of new phosphonites with a chiral paracyclophane backbone is described. The Rh complexes derived from the phosphonites (e.g. I) bearing biphenoxy and binaphthoxy substituents are highly active and highly selective catalysts for the asym. hydrogenation of dehydroamino acids and esters. For example, >99% N-acetylalanine Me ester with 99 %ee was obtained in 1/2 h using the Rh complex of I.(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4SDS of cas: 329735-68-4) was used in this study.

(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4) belongs to phenols. Phenols are more acidic than typical alcohols.SDS of cas: 329735-68-4 The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chapuis, Christian; Buchi, George H.; Wuest, Hans published their research in Helvetica Chimica Acta on December 23 ,2005. The article was titled 《Synthesis of cis-Hedione and methyl jasmonate via cascade Baylis-Hillman reaction and Claisen ortho ester rearrangement》.Product Details of 329735-68-4 The article contains the following contents:

The exocyclically unsaturated conjugated keto esters I (R = n-Bu, n-hexyl, PhCH2OCH2, etc., R1 = Me, Et), obtained via a Claisen ortho ester rearrangement of the allylic hydroxy ketones II, were either directly hydrogenated or partially isomerized into the endocyclically unsaturated tetrasubstituted didehydrojasmonoid intermediates III, prior to a more selective hydrogenation with Pd/C in cyclohexane to the disubstituted oxocyclopentaneacetates IV. The key intermediates II were obtained either by a four-step sequence, including acetal protection/deprotection from enone V, in the specific case of hydroxy ketone II (R = n-Bu), or more directly and generally by a Baylis-Hillman reaction from cyclopent-2-en-1-one and the appropriate aldehydes RCHO. The judicious choice of these aldehydes opens versatile modifications for the stereoselective introduction of the partially cis- or epimerized trans-C(2) jasmonoid side chain, while the Baylis-Hillman reaction, catalyzed by chiral [1,1′-binaphthalene]-2,2′-diols (BINOLs), may be efficiently conducted in a one-pot cascade fashion including the ortho ester Claisen rearrangement.(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4Product Details of 329735-68-4) was used in this study.

(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4) belongs to phenols. Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12).Product Details of 329735-68-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2015,Chemistry – A European Journal included an article by Kamikawa, Ken; Arae, Sachie; Wu, Wei-Yi; Nakamura, Chihiro; Takahashi, Tamotsu; Ogasawara, Masamichi. SDS of cas: 329735-68-4. The article was titled 《Simultaneous induction of axial and planar chirality in arene-chromium complexes by molybdenum-catalyzed enantioselective ring-closing metathesis》. The information in the text is summarized as follows:

1,3-Diisopropenyl-2-R-benzene ligands (Ar, R = 1-pyrrolyl, halo, methoxy, 1-indenyl, 1-naphthyl) in arenechromium allylphosphine complexes [(η6-Ar)Cr(CO)2(tBu2PCH2CH:CH2)] (1a-r) undergo asym. ring-closing metathesis between isopropenyl and allyl groups, catalyzed by molybdenum RCM catalysts, giving planar chiral arenechromium complexes with pendant phosphine, [(η6,κP-1-tBu2PCH2CH:CMe-2-R-3-isopropenylbenzene)Cr(CO)2] (2a-r), which, in the case of unsym. R groups, such as 1-indolyl or 1-naphthyl, also feature atropisomeric axial chirality of the arene-R bond. The molybdenum-catalyzed asym. ring-closing metathesis of the various Cs-sym. (π-arene)chromium substrates provides the corresponding bridged planar-chiral (π-arene)chromium complexes in excellent yields with up to >99 % ee. The axial chirality is retained even after the removal of the dicarbonylchromium fragment, and the chiral biaryl/heterobiaryl compounds are obtained with complete retention of the enantiopurity. The experimental part of the paper was very detailed, including the reaction process of (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4SDS of cas: 329735-68-4)

(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4) belongs to phenols. Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12).SDS of cas: 329735-68-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Alternatives to Phosphinooxazoline (t-BuPHOX) Ligands in the Metal-Catalyzed Hydrogenation of Minimally Functionalized Olefins and Cyclic β-Enamides》 was published in Advanced Synthesis & Catalysis in 2017. These research results belong to Biosca, Maria; Magre, Marc; Coll, Merce; Pamies, Oscar; Dieguez, Montserrat. Synthetic Route of C24H34O2 The article mentions the following:

A new series of readily accessible iridium- and rhodium-phosphite/oxazoline catalytic systems that can efficiently hydrogenate, for the first time, both minimally functionalized olefins and functionalized olefins, such as Et 3-phenylbut-2-enoate, Et (2Z)-3-cyclohexyl-3-phenylprop-2-enoate, [(1E)-1-methyl-1-propen-1-yl]benzene, etc. (62 examples in total), with high enantioselectivities (up to >99% ee) and conversions has been reported. The phosphite-oxazoline ligands, which are readily available in only two synthetic steps, are derived from previous privileged 4-alkyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline (PHOX) ligands by replacing the phosphine moiety by a biaryl phosphite group and/or the introduction of a methylene spacer between the oxazoline and the Ph ring. The modular design of the ligands has given the opportunity not only to overcome the limitations of the iridium-PHOX catalytic systems in the hydrogenation of minimally functionalized Z-olefins and 1,1-disubstituted olefins, but also to expand their use to unfunctionalized olefins containing other challenging scaffolds (e.g., exocyclic benzo-fused and triaryl-substituted olefins) and also to olefins with poorly coordinative groups (e.g., α,β-unsaturated lactams, lactones, alkenylboronic esters, etc.) with enantioselectivities typically >95% ee. Moreover, both enantiomers of the hydrogenation product could be obtained by simply changing the configuration of the biaryl phosphite moiety. Remarkably, the new catalytic systems also provided excellent enantioselectivities (up to 99% ee) in the asym. hydrogenation of another challenging class of olefins – the functionalized cyclic β-enamides, such as N-(6-bromo-3,4-dihydronaphthalen-2-yl)acetamide, N-(2H-chromen-3-yl)acetamide, N-(8-methoxy-3,4-dihydronaphthalen-2-yl)acetamide, etc. Again, both enantiomers of the reduced amides could be obtained by changing the metal from Ir to Rh. The environmentally friendly propylene carbonate which can be used with no loss of enantioselectivity was also demonstrated. Another advantage of the new ligands over the PHOX ligands is that the best ligands are derived from the affordable (S)-phenylglycinol rather than from the expensive (S)-tert-leucinol.(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4Synthetic Route of C24H34O2) was used in this study.

(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4) belongs to phenols. Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12).Synthetic Route of C24H34O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Application of 329735-68-4On October 31, 2008 ,《Conversion of propargylic alcohols to β-oxo esters catalyzed by novel ruthenium-phosphoramidite complexes》 appeared in Advanced Synthesis & Catalysis. The author of the article were Costin, Stephen; Rath, Nigam P.; Bauer, Eike B.. The article conveys some information:

A series of half-sandwich phosphoramidite complexes of ruthenium were synthesized and employed as catalysts in the atom-economical formation of β-oxo esters from carboxylic acids and propargylic alcs. Reaction of the phosphoramidites (R)-BINOL-PNR2 (R = Me, 1a; i-Pr, 1b; benzyl, 1c) and (rac)-6,6′-dibromo-BINOL-PNMe2 (1d) with the dimeric p-cymene-ruthenium dichloride complex, [RuCl2(p-cymene)]2, gave the complexes [RuCl2(p-cymene)(L)] (L = 1a, 7a; 1b, 7b; 1c, 7c; 1d, 7d) in 96-66% yield. Accordingly, reaction of (R)-BINOL(8H)-PNMe2 (2a) and (R)-BINOL(8H)-PN(benzyl)2 (2b) with [RuCl2(p-cymene)]2 afforded the complexes [RuCl2(p-cymene)(L)] (L = 2a, 8a; 2b, 8b) in 82% and 86% yield. In a similar reaction, treatment of (R)-BIPHEN-PNMe2 (9) with [RuCl2(p-cymene)]2 gave the complex [RuCl2(p-cymene)(9)] (11) in 60% yield. Finally, phosphoramidite 1b reacted with [RuCl2(C6Me6)]2 to give [RuCl2(C6Me6)(1b)] (12) in 78% yield. All novel complexes are catalytically active in the formation of β-oxo esters from propargylic alcs. and carboxylic acids. Standard conditions involve cyclohexane solvent, propargylic alc. (1.0 equivalent), carboxylic acid (1.0 equivalent), ruthenium catalyst (1.5 mol%), and 90° for 5-18 h. Isolated yields of the β-oxo esters range from 87 to 16% and show broad substrate generality. The reaction proceeds without racemization if a chiral propargylic alc. is employed. The method is practical as no additives are required and the exclusion of oxygen and moisture is not needed. Complex 7c turned out to be the most effective catalyst (5 h reaction time), showing that the ligand structure has a profound impact on the catalytic performance. The crystal structure of 7a was determined, confirming an octahedral coordination geometry about the ruthenium center. The results came from multiple reactions, including the reaction of (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4Application of 329735-68-4)

(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4) belongs to phenols. Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12).Application of 329735-68-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2008,Chemistry – An Asian Journal included an article by Gabert, Andrea J.; Schrock, Richard R.; Muller, Peter. Computed Properties of C24H34O2. The article was titled 《Synthesis of bifunctional imido alkylidene bispyrrolide complexes of molybdenum and their conversion into bifunctional imido alkylidene diolate complexes that can be employed as ROMP initiators》. The information in the text is summarized as follows:

Addition of four equivalent of lithium 2,5-dimethylpyrrolide to a solution of [Mo(NAr)(ORF6)2(CHC5H4)]2Fe (ORF6 = OCMe(CF3)2) in dichloromethane led to [Mo(NAr)(Me2Pyr)2(CHC5H4)]2Fe (I) where Me2Pyr = 2,5-dimethylpyrrolide and lithium hexafluoro-tert-butoxide, which crystallizes out upon cooling the reaction mixture to -35°C. Attempts to prepare parent pyrrolide complexes analogous to I resulted in the formation of a mixture of two products. The one that could be isolated contains one equivalent of lithium pyrrolide per molybdenum, that is [Mo(NAr)(Pyr)3(CHC5H4)]2FeLi2 (II). The X-ray structure obtained shows it to be a dimer of dimers in which each lithium atom is bound to three pyrrolides. Addition of four equivalent of lithium 2,5-dimethylpyrrolide to [Mo(NAr)(ORF6)2]2(DME)2(CH-1,4-C6H4CH) in cold DME produced [Mo(NAr)(Me2Pyr)2]2(CH-1,4-C6H4CH) (III) in good yield, in which the bridging alkylidene is derived from 1,4-divinylbenzene. Three equivalent of (S)-H2[Biphen] are required for a clean reaction with II to form [Mo(NAr)(Biphen)(CHC5H4)]2Fe (IV) (H2[Biphen]=3,3′-di-tert-butyl-5,5′,6,6′-tetramethyl-1,1′-biphenyl-2,2′-diol), Li2[Biphen], and two equivalent of pyrrole. Reactions involving III with the chiral diols are the best behaved. Brown [Mo(NAr)(Benz2Bitet)]2(CH-1,4-C6H4CH) (V) can be isolated upon addition of (R)-H2[Benz2Bitet] H2[Benz2Bitet] = (3,3′-dibenzhydryl-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl-2,2′-diol) to 4, while addition of (R)-H2[Mes2Bitet] (H2[Mes2Bitet] = 3,3′-dimesityl-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl-2,2′-diol) to 4 yields [Mo(NAr)(Mes2Bitet)]2(CH-1,4-C6H4CH) (VI). Compounds IV, V, and VI were employed as initiators for the polymerization of 2,3-dicarbomethoxynorbornadiene (DCMNBD) and 2,3-bis(trifluoromethyl)norbornadiene (NBDF6).(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4Computed Properties of C24H34O2) was used in this study.

(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4) belongs to phenols. Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12).Computed Properties of C24H34O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Recommanded Product: (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diolOn October 6, 2003 ,《Synthesis and characterization of new biphenolate and binaphtholate rare-earth-metal amido complexes: Catalysts for asymmetric olefin hydroamination/cyclization》 was published in Chemistry – A European Journal. The article was written by Gribkov, Denis V.; Hultzsch, Kai C.; Hampel, Frank. The article contains the following contents:

Monomeric diolate amido yttrium complexes [Y{diolate}{N(SiHMe2)2}(THF)2] can be prepared in good yield by treating [Y{N(SiHMe2)2}3(THF)2] with either 3,3′-di-tert-butyl-5,5′,6,6′-tetramethyl-1,1′-biphenyl-2,2′-diol (H2(Biphen)), 3,3′-bis(2,4,6-triisopropylphenyl)-2,2′-dihydroxy-1,1′-dinaphthyl (H2(Trip2BINO)) or 3,3′-bis(2,6-diisopropylphenyl)-2,2′-dihydroxy-1,1′-dinaphthyl (H2(Trip2BINO)) in racemic and enantiopure form. The racemic complex [Y(biphen){N(SiHMe2)2}(THF)2] dimerizes upon heating to give the heterochiral complex (R,S)-[Y(biphen){N(SiHMe2)2}(THF)]2. The corresponding dimeric heterochiral lanthanum complex was the sole product in the reaction of H2(Biphen) with [La{N(SiHMe2)2}3(THF)2]. Single-crystal x-ray diffraction of both dimeric complexes revealed that the two Ln(biphen){N(SiHMe2)2}(THF) fragments are connected through bridging phenolate groups of the biphenolate ligands. The two different phenolate groups undergo an intramol. exchange process in solution leading to their equivalence on the NMR timescale. All complexes were active catalysts for the hydroamination/cyclization of aminoalkynes and aminoalkenes at elevated temperature, with [Y((R)-dip2bino){N(SiHMe2)2}(THF)2] being the most active one giving enantioselectivities of up to 57% ee. Kinetic resolution of 2-aminohex-5-ene proceeded with this catalyst with 6.4:1 trans selectivity to give 2,5-dimethylpyrrolidine with a krel of 2.6. After reading the article, we found that the author used (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4Recommanded Product: (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol)

(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4) belongs to phenols. Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12).Recommanded Product: (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Recommanded Product: 329735-68-4On September 30, 2021 ,《Novel BIPHEN H2 based P,S-bidentate phosphoramidite ligand in palladium-catalyzed asymmetric allylation》 was published in Mendeleev Communications. The article was written by Gavrilov, Konstantin N.; Chuchelkin, Ilya V.; Zheglov, Sergey V.; Firsin, Ilya D.; Trunina, Valeria M.; Gavrilov, Vladislav K.; Borisova, Nataliya E.; Zimarev, Vladislav S.; Denesh, Andrey A.; Goulioukina, Nataliya S.. The article contains the following contents:

The reaction of P,S-phosphoramidite bearing (Ra)-BIPHEN H2 core and exocyclic amino sulfide as the new ligand with [Pd(ppp-allyl)Cl]2 in the presence of AgBF4 yielded a cationic metallochelate [Pd(ppp-allyl)(L)]BF4. This new chiral inducer provided up to 90% ee in the Pd-mediated allylic substitution reaction of (E)-1,3-diphenylallyl acetate with various C- and N-nucleophiles. In the Pd-catalyzed amination of 2-diethoxyphosphoryl-1-phenylallyl acetate with aniline, ee values up to 57% were achieved. In the part of experimental materials, we found many familiar compounds, such as (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4Recommanded Product: 329735-68-4)

(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4) belongs to phenols. Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12).Recommanded Product: 329735-68-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2015,Chemistry – A European Journal included an article by Vidal-Ferran, Anton; Mon, Ignasi; Bauza, Antonio; Frontera, Antonio; Rovira, Laura. Reference of (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol. The article was titled 《Supramolecularly Regulated Ligands for Asymmetric Hydroformylations and Hydrogenations》. The information in the text is summarized as follows:

The use of polyether binders as regulation agents (RAs) to enhance the enantioselectivity of rhodium-catalyzed transformations has been reported. For reactions of diverse substrates mediated by rhodium complexes of the α,ω-bisphosphite-polyether ligands such as I [X = (OCH2CH2)3], the enantiomeric excess (ee) of hydroformylations was increased by up to 82% (substrate: vinyl benzoate, 96% ee), and the ee value of hydrogenations was increased by up to 5% (substrate: N-(1-(naphthalene-1-yl)vinyl)acetamide, 78% ee). The ligand design enabled the regulation of enantioselectivity by generation of an array of catalysts that simultaneously preserve the advantages of a privileged structure in asym. catalysis and offer geometrically close catalytic sites. The highest enantioselectivities in the hydroformylation of vinyl acetate with a tetra(ethylene glycol) bis(binaphthylphosphite) were achieved by using the Rb[B(3,5-(CF3)2C6H3)4] (RbBArF) as the RA. The enantioselective hydrogenation of alkenes R1CH=C(R2)(XC(O)G) [R1 = H, Ph; R2 = CO2CH3, 1-naphthyl; X = CH2, NH, NHCH2; G = OMe, C(O)Me] required rhodium catalysts derived from either a biphenylbis(tetra(ethylene glycol)) bis(binaphthylphosphite) or a tetra(ethylene glycol) bis(binaphthylphosphite) either alone or in combination with different RAs (sodium, cesium, or (R,R)-bis(1-phenylethyl)ammonium salts). This design approach was supported by results from computational studies.(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4Reference of (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol) was used in this study.

(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4) belongs to phenols. Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12).Reference of (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2013,Chemistry – A European Journal included an article by Ogasawara, Masamichi; Arae, Sachie; Watanabe, Susumu; Nakajima, Kiyohiko; Takahashi, Tamotsu. Category: alcohols-buliding-blocks. The article was titled 《Kinetic Resolution of Planar-Chiral 1,2-Disubstituted Ferrocenes by Molybdenum-Catalyzed Asymmetric Intraannular Ring-Closing Metathesis》. The information in the text is summarized as follows:

The kinetic resolution of racemic planar-chiral 1,2-disubstituted ferrocene derivatives, e.g., rac-1-allyl-2-methallylferrocene (1b) was accomplished through a Mo catalyzed asym. intrannular ring-closing metathesis reaction. E.g., rac-1b reacted with the precatalysts, Mo(:NC6H3-2,6-iPr2)(:CHCMe2Ph)(NC4H2)2/(R)-3,3′-(2,4,6-iPr3C6H2)2-binaphthol (5 mol%) in dry benzene at room temperature to give (S)-1b in 37% yield (96% ee) and (+)(η5-cyclopentadienyl)(η5-4,7-dihydro-5-methylindenyl)iron(II) in 60% yield (72% ee). In the experimental materials used by the author, we found (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4Category: alcohols-buliding-blocks)

(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4) belongs to phenols. Phenols are more acidic than typical alcohols.Category: alcohols-buliding-blocks The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts