Category: 31110-78-8

The author of 《Gas-chromatographic analysis of aminothiol radioprotective compounds》 were Lofberg, R. T.. And the article was published in Analytical Letters in 1971. Formula: C5H14ClNS The author mentioned the following in the article:

A gas chromatog. method is described for aminothiols and disulfides. This method is based upon the formation of the trimethylsilyl derivatives and their separation by gas chromatog. The kinetics of the derivative formation were investigated. A synthetic method for C4 to C6 aminothiols is given.5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8Formula: C5H14ClNS) was used in this study.

5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8) belongs to thiols. Thiols show many reactions like those of the hydroxyl compounds, such as formation of thioesters and thioethers (sulfides). Toward oxidation, however, they differ profoundly from alcohols: whereas oxidation of an alcohol usually leads to a product in which the oxidation state of a carbon atom has been changed, oxidation of a thiol affects the sulfur atom. Formula: C5H14ClNS

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2003,Tetrahedron Letters included an article by Mourtas, Spyros; Katakalou, Christina; Nicolettou, Andriana; Tzavara, Chryssoula; Gatos, Dimitrios; Barlos, Kleomenis. Related Products of 31110-78-8. The article was titled 《Resin-bound aminothiols: synthesis and application》. The information in the text is summarized as follows:

Aminothiols were attached through their thiol group onto the 4,4′-dimethoxytrityl (Dmt)-, 4-methoxytrityl (Mmt)-, 4-methyltrityl (Mtt)-, trityl (Trt)- and 2-chlorotrityl (Clt)-resins. The new resins were used in the solid-phase synthesis of aminothiol containing peptides utilizing N-Fmoc amino acids. The synthesized peptides were cleaved from the resins by treatment with trifluoroacetic acid (TFA) solutions using triethylsilane (TES) or ethanedithiol (EDT) as scavengers. The results came from multiple reactions, including the reaction of 5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8Related Products of 31110-78-8)

5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8) belongs to thiols. Thiols show many reactions like those of the hydroxyl compounds, such as formation of thioesters and thioethers (sulfides).Related Products of 31110-78-8 Toward oxidation, however, they differ profoundly from alcohols: whereas oxidation of an alcohol usually leads to a product in which the oxidation state of a carbon atom has been changed, oxidation of a thiol affects the sulfur atom.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Structure-function studies of the aminothiol radioprotectants. Effect of carbon chain length in mercaptoethylamine homologs. Mammalian radioprotection》 was published in Radiation Research in 1971. These research results belong to Grenan, Marie M.; Copeland, Edmund S.. Safety of 5-Aminopentane-1-thiol hydrochloride The article mentions the following:

Of the 5 aminothiols (I) studied, only β-mercaptoethylamine-HCl (II) (0.7 mM/kg, i.p.) showed a radioprotective effect in mice treated with an LD70(30) radiation dose (875 rads). This result is in contrast to those of previous studies in bacteria where pharmacological effects were avoided and only phys.-chem. effects were studied. In the experiment, the researchers used many compounds, for example, 5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8Safety of 5-Aminopentane-1-thiol hydrochloride)

5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8) belongs to thiols. Thiols show many reactions like those of the hydroxyl compounds, such as formation of thioesters and thioethers (sulfides). Toward oxidation, however, they differ profoundly from alcohols: whereas oxidation of an alcohol usually leads to a product in which the oxidation state of a carbon atom has been changed, oxidation of a thiol affects the sulfur atom. Safety of 5-Aminopentane-1-thiol hydrochloride

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Structure-function studies of the aminothiol radioprotectants. Effect of carbon chain length in mercaptoethylamine homologs》 was published in Radiation Research in 1971. These research results belong to Swartz, Harold M.; Copeland, Edmund S.; Richardson, Earl C.. COA of Formula: C5H14ClNS The article mentions the following:

A study of the relation between chemical structure of aminothiols such as β-mercaptoethylamine-HCl (I) and its propyl, butyl, pentyl, and hexyl homologs, and the phys. chem. radiation protection in Escherichia coli which were irradiated in the presence of 0.1M protectant at either 1°C or 77°K and equilibrated with 100% O2 or N2 prior to irradiation showed that in contrast to mammalian systems no abrupt reduction in radioprotection occurred when the carbon chain separating amino acids and thiol groups was lengthened from 3 to 4 or more units. Free radical studies which were observed by ESR spectroscopy of treated bacteria preparations irradiated at 77°K and bacteriolog. studies indicated a gradual decrease in efficiency with no change in the mechanism of action either in O2 or N2. These results suggest a protective effect of aminothiols by specific interactions with cell components in addition to acting via a more general, non-specific radical scavenging and (or) repair mechanism. The experimental process involved the reaction of 5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8COA of Formula: C5H14ClNS)

5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8) belongs to thiols. Thiols show many reactions like those of the hydroxyl compounds, such as formation of thioesters and thioethers (sulfides).COA of Formula: C5H14ClNS Toward oxidation, however, they differ profoundly from alcohols: whereas oxidation of an alcohol usually leads to a product in which the oxidation state of a carbon atom has been changed, oxidation of a thiol affects the sulfur atom.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts