Electric Literature of 3068-00-6, Adding some certain compound to certain chemical reactions, such as: 3068-00-6, name is 1,2,4-Butanetriol,molecular formula is C4H10O3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3068-00-6.
To a 500 ml_ flask, 1 ,2,4-trihydroxybutane (III, 159 g, 1.5 mol, 1 equ.) and p-toluenesulfonic acid monohydrate (1.5 g, 8.72 mmol, 0.006 equ.) were added. The solution was heated to 160-180 C. Reaction was monitored by GC. The resulting mixture was purified by fractional distillation to give 3-OH-tetrahydrofuran as colorless oil (120.5 g 91.3% yield): bp 86-88 C (23 mmHg) 1H NMR (400 MHz, CDCI3) delta 4.43-4.42 (1 H, t), 3.95-3.67 (4H, m), 3.08- 3.07 (1 H, d), 2.07-1.82 (2H, m). GCMS m/z 88 (M+).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 3068-00-6, 1,2,4-Butanetriol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL TRADING (SHANGHAI) CO., LTD; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; XING, Lidong; DONG, Weitong; LU, Jun; SCHOLZ, Ulrich; YAN, Jun; YANG, Jinsong; WO2014/140017; (2014); A1;,
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