Category: 2807-30-9

Synthetic Route of 2807-30-9 , The common heterocyclic compound, 2807-30-9, name is 2-Propoxyethanol, molecular formula is C5H12O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

General procedure: A mixture of the corresponding 4-((1H-benzo[d][1,2,3]triazol-1-yl)oxy)-6-aryl-3,4,5,6-tetrahydropyrido[2,3-d]pyrimidine-7(8H)-one (14{x}) (0.42mmol), Cs2CO3 (0.54mmol) and the corresponding alcohol (9mL) was heated a reflux overnight. The resulting solution was cooled down, water (100mL) was added and the reaction crude was neutralized with 2M HCl. The resulting solid was collected by filtration and washed with water, and EtOEt to afford the corresponding 15{x,y}. Starting from compound 14{5} and 2-propoxyethanol to afford 15{5,9} in 38% yield, white solid. IR (KBr), numax (cm-1): 3479, 3332, 3220, 2773, 1692, 1631, 1575, 1458, 1435, 1373, 777. 1H NMR (400 MHz, DMSO-d6): delta 10.51 (s, 1H, NH), 7.58-7.47 (m, 2H, C13-CH), 7.37 (t, J = 8.1 Hz, 1H, C14-CH), 6.42 (s, 2H, NH2), 4.63 (dd, J = 12.9, 9.2 Hz, 1H, C7-CH), 4.35-4.32 (m, 2H, C15-CH2), 3.63 (t, J = 4.9 Hz, 2H, C16-CH2), 3.35 (t, J = 6.6 Hz, 2H, C17-CH2), 2.93-2.79 (m, 2H, C6-CH2), 1.46 (h, J = 7.3 Hz, 2H, C18-CH2), 0.80 (t, J = 7.4 Hz, 3H, CH3). 13C NMR (100.6 MHz, DMSO-d6): delta 169.6, 166.4, 161.8, 158.0, 135.3, 135.1, 129.8, 128.3, 85.2 (C5), 71.9 (C17), 68.2 (C16), 65.0 (C15), 43.1 (C7), 22.4 (C18), 22.2 (C16), 10.4 (C19). Anal. Calcd. (%) for C18H20Cl2N4O2: C, 52.57; H, 4.90; N, 13.62. Found: C, 52.76; H, 5.12; N, 13.98.

The synthetic route of 2807-30-9 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Camarasa, Marta; De La Bellacasa, Raimon Puig; Gonzalez, Alex L.; Ondono, Rauel; Estrada, Roger; Franco, Sandra; Badia, Roger; Este, Jose; Martinez, Miguel Angel; Teixido, Jordi; Clotet, Bonaventura; Borrell, Jose I.; European Journal of Medicinal Chemistry; vol. 115; (2016); p. 463 – 483;,
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Application of 2807-30-9 ,Some common heterocyclic compound, 2807-30-9, molecular formula is C5H12O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

(1) Weigh 100g ethylene glycol mono-n-propyl ether,0.3 g of N, N-dimethylaniline,This was added to the reaction vessel with a reflux condenser,115.97 g of thionyl chloride (content of 99.3%, sulfuryl chloride content of 0.5%) was added to a constant pressure dropping funnel,Warming up to 35 C, turning on stirring,Thionyl chloride was slowly added dropwise to the reaction vessel to release sulfur dioxide and hydrogen chloride gas during the reaction,Control thionyl chloride dropping speed,The temperature of the reaction solution was maintained at 60 ± 5 C;(2) until the thionyl chloride is added dropwise,According to the reaction gas evolution rate gradually warmed to 95 ,Until no gas release, continue to heat 1h get crude,After the crude product is cooled down to 40 C, a certain amount of lye is added and stirred,The remaining thionyl chloride decomposition and neutralization of acid,Then add a certain amount of water for hydrolysis,After standing for liquid separation, 117.65 g of 2-propoxychloroethane was obtained.After testing, the chromatographic content of the product was 99.84%Yield of 99.89%.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 2807-30-9, 2-Propoxyethanol, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Shandong Kaisheng New Materials Co., Ltd.; Shi Yufei; Zhang Taiming; Han Nannan; Wang Ronghai; Xue Juqiang; Wang Jun; Li Guanghui; Huang Guiqing; (5 pag.)CN106831368; (2017); A;,
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Chemistry, like all the natural sciences, SDS of cas: 2807-30-9, begins with the direct observation of nature— in this case, of matter.2807-30-9, Name is 2-Propoxyethanol, SMILES is CCCOCCO, belongs to alcohols-buliding-blocks compound. In a document, author is Yasmin, Alvi, introduce the new discover.

Transcriptional regulation of alcohol induced liver fibrosis in a translational porcine hepatocellular carcinoma model

Hepatocellular carcinoma (HCC) is the 5th most common and 2nd deadliest cancer worldwide. HCC risk factors include alcohol induced liver cirrhosis, which prompts hepatic inflammation, cell necrosis, and fibrosis deposition. As 25% of HCC cases are associated with alcohol induced liver disease, understanding the effects of the cirrhotic liver microenvironment on HCC tumor biology and therapeutic responses are critical. This study utilized the Oncopig Cancer Model-a transgenic pig model that recapitulates human HCC through induced expression of KRAS(G12D) and TP53(R167H )driver mutations-to investigate the molecular mechanisms underlying alcohol induced liver disease. Oncopigs (n = 5) underwent fibrosis induction via infusion of ethanol and ethiodized oil (1:3 v/v dosed at 0.75 mL/kg) into the hepatic arterial circulation. Eight-weeks post induction, liver tissue samples from fibrotic and age-matched control (n = 5) Oncopigs were collected for histological evaluation and transcriptional profiling. Increased hepatic inflammation and fibrosis was observed in fibrotic Oncopigs via pathological assessment. Transcriptional profiling (RNA-seq) resulted in the identification of 4387 differentially expressed genes between Oncopig fibrotic and control livers. GO term enrichment analysis identified pathway alterations associated with cirrhosis progression in humans, including cell proliferation, angiogenesis, extracellular matrix deposition, and oxidation-reduction. Key alterations include activation of hepatic stellate cells, increased matrix metalloproteinase production, and altered expression of ABC and SLC transporter genes involved in transport of anticancer drugs.These results demonstrate Oncopig liver fibrosis recapitulates transcriptional hallmarks of human cirrhosis, making the Oncopig an ideal model for studying the effects of the cirrhotic liver microenvironment on HCC tumor biology and therapeutic response. (C) 2021 Elsevier B.V. and Societe Francaise de Biochimie et Biologie Moleculaire (SFBBM). All rights reserved.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 2807-30-9. SDS of cas: 2807-30-9.

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Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Schripp, Tobias, once mentioned the application of 2807-30-9, Name is 2-Propoxyethanol, molecular formula is C5H12O2, molecular weight is 104.1476, MDL number is MFCD00072645, category is alcohols-buliding-blocks. Now introduce a scientific discovery about this category, Formula: C5H12O2.

Technical application of a ternary alternative jet fuel blend – Chemical characterization and impact on jet engine particle emission

The use of alternative fuels is an essential element in future aviation. There are currently different approaches with regard to fuel production processes and feedstock materials. This requires flexible handling of available fuel quantities. The production of fuel mixtures (blends) is inevitable for an effective usage of commercially available fuel components. Within the framework of the project DEMO-SPK approx. 600 t of a ternary mixture (multiblend) of alternative jet fuels was produced and used in a real airport infrastructure at the airport Leipzig/Halle. Production and application were accompanied by extensive R&D activities to show that on-spec, semi-synthetic multiblends can be produced from several different synthetic fuels. One important aspect is the emission of soot particles from aircraft engines. The Multiblend Jet A-1 has been analyzed in a flow reactor setup regarding the formation of soot precursor compounds in comparison to a reference Jet A-1. The experiment revealed a lower formation of relevant soot precursors which also corresponds to the higher hydrogen content of the Multiblend Jet A-1 compared to the reference fuel. The lower soot formation in a real aircraft engine has been proven during ground runs of an A300-600 aircraft with PW4158 engines. The Multiblend Jet A-1 showed lower particle number and particle mass emission than the reference fuel. The difference to the reference fuel decreased with increasing power settings. In summary, the emission of particle mass is reduced by similar to 29 % and the number of emitted particles is reduced by similar to 37 % if the ICAO landing-and-take-off cycle is used for evaluation.

If you are interested in 2807-30-9, you can contact me at any time and look forward to more communication. Formula: C5H12O2.

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Related Products of 2807-30-9, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 2807-30-9, Name is 2-Propoxyethanol, SMILES is CCCOCCO, belongs to alcohols-buliding-blocks compound. In a article, author is Wu, Xianwen, introduce new discover of the category.

Na-containing manganese-based cathode materials synthesized by sol-gel method for zinc-based rechargeable aqueous battery

Zinc-based rechargeable aqueous batteries are regarded as one of the most safe and inexpensive energy storage systems compared to the conventional rechargeable batteries with organic electrolytes. However, the limited cathode materials and the problem of associated metal ion dissolution restrict its practical application. Herein, the inexpensive novel cathode materials of Na-containing manganese-based composite of Na0.44MnO2 /Mn2O3 and Na2/3Fe1/2Mn1/2O2 are designed and synthesized correspondingly by sol-gel methods combined with freeze-drying technique, and are applied in the zinc-based aqueous batteries for the first time. The secondary particles of Na0.44MnO2/Mn2O3 composite with a cubic box and the molecular sieve configurations are composed of nano primary particles with about 150-300 nm, and the obtained O3-Na2/3Fe1 /2Mn1/2O2 at 850 degrees C (O3-NFM-850) appears to homogenous distribution with 3D solid block structure and platelet-shaped particles, while the spherical core-shell structure of P2 -Na2/3Fe1/2Mn1/2O2 at 850 degrees C (P3-NFM-850-PVA) after dispersed by poly (vinyl alcohol) are linked to each other by amorphous carbon. Finally, the cathode of Na0.44MnO2/Mn2O3 and P3-NFM-850-PVA deliver the reversible capacities of 68.3 mAh g(-1) and 42 mAh g(-1) even after 200 cycles at 0.4 A/g respectively without capacity fading. Compared to the reported Na0.44MnO2, the increased capacity ofNa(0.44)MnO(2)/Mn2O3 composite is attributed to the possible co-insertion of sodium ion and zinc ion for Na0.44MnO2 and the zinc ion insertion for Mn203 as well, indicating the synergetic energy storage for rechargeable hybrid aqueous battery and aqueous zinc ion battery. While the improved cyclic performance of Na2/3Fe1/2Mn1/2O2 is ascribed to the structural stability by Fe-doping and carbon-coating. (C) 2020 Elsevier B.V. All rights reserved.

Related Products of 2807-30-9, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 2807-30-9 is helpful to your research.

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Related Products of 2807-30-9, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 2807-30-9, Name is 2-Propoxyethanol, SMILES is CCCOCCO, belongs to alcohols-buliding-blocks compound. In a article, author is Shi, Jun, introduce new discover of the category.

Inhibition effect of methanol addition on carbon deposition in propane pyrolysis

Methanol-mixed fuels consisting of methanol, propane, and a small amount of auxiliary solvent are widely used as inexpensive industrial fuels, but the carbon deposition in the pyrolysis of this fuel seriously restrains its popularization. This paper studied the characteristics of gaseous products and carbon deposition in the pure propane and methanol-propane mixture pyrolysis experimentally, analyzed the effect of methanol addition on the reaction path of propane pyrolysis and production rate of key species by using detailed reaction mechanism. Results show that methanol addition can restrain C2H4 converting to C2H2 in the later stage of pyrolysis. The carbon deposition rate and particle diameter increase exponentially with the increase of reaction temperature in both pure propane and methanol-propane blend pyrolysis. Methanol addition can significantly reduce the carbon deposition rate and particle diameter. The reaction path analysis indicates that the main reaction paths forming benzene are C3H3 -> A1 and C4H4 -> I-C6H6 -> A1, and C3H3 is a key specie to form benzene. The pyrolysis of methanol-propane mixture generates more H-2 and H than that of pure propane pyrolysis, which makes most C3H6 convert to C2H4, reduces the amount of C3H3 and suppresses the conversion of C2H4 to C2H2. And then the amount of benzene is reduced significantly and the generation of subsequent PAHs and carbon deposition is inhibited. Lots of H-2 also restrains the hydrogen abstraction from benzene resulting in the delay of the formation of PAHs and carbon deposition. This study is of great significance to research the soot formation in hydrocarbon combustion with alcohol fuel.

Related Products of 2807-30-9, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 2807-30-9.

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Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 2807-30-9, Name is 2-Propoxyethanol, SMILES is CCCOCCO, belongs to alcohols-buliding-blocks compound. In a document, author is Aredes, Rafaella Silva, introduce the new discover, Formula: C5H12O2.

Evaluation of craft beers through the direct determination of amino acids by capillary electrophoresis and principal component analysis

The composition of beer wort in terms of amino acid (AA) content affects the final product quality, once it is related to the vitality of yeast during the initial exponential growth phase and throughout fermentation. The objective of this work was the use of a capillary zone electrophoresis method with UV-vis detection in association with Principal Component (Data) Analysis for craft beer classification. Cysteine, histidine, phenylalanine, lysine, tryptophan and arginine were the monitored AAs in wort and finished beer, which were extracted through cation exchange resin. Good differentiation among samples according to their production was obtained, showing a profile of AAs (6.5-55 mu g mL(-1)), which can be explained by the protein cleavage.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 2807-30-9 is helpful to your research. Formula: C5H12O2.

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In an article, author is Xiang, Aimin, once mentioned the application of 2807-30-9, Name is 2-Propoxyethanol, molecular formula is C5H12O2, molecular weight is 104.1476, MDL number is MFCD00072645, category is alcohols-buliding-blocks. Now introduce a scientific discovery about this category, Name: 2-Propoxyethanol.

Multifunctional nucleating agents with simultaneous plasticizing, solubilizing, nucleating and their effect on polyvinyl alcohol foams

Currently, preparing microcellular polymer foams by supercritical CO2(Sc-CO2) is a newly trend and challenge. The main limitation of Sc-CO2 used in microcellular foaming industry is its solubility. In this paper, four kinds of amines (formamide, ethylenediamine, polyamide dendrimer (PAMAM) and polyhedral oligomeric silsesquioxane (POSS)) were introduced into polyvinyl alcohol (PVA) to improve the foaming behaviors. The results of differential scanning calorimetry showed that formamide and POSS could plasticize PVA to a certain extent. Through SEM analysis, formamide and ethylenediamine has a nucleating effect and improves the foaming effect. Furthermore, the content of formamide has a great influence on the foaming behavior of PVA. TG-IR analysis showed that -NH2 can react with CO2 to form -HNCOO- at normal temperature and pressure, which contributed to the diffusion of CO2 and improved the uniformity of cell size. With increasing formamide content, the cell density increased from 3.22 x 10(9) cm(-3) to 1.79 x 10(10) cm(-3).

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The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 2807-30-9, Name is 2-Propoxyethanol, SMILES is CCCOCCO, in an article , author is Power, Aoife C., once mentioned of 2807-30-9, Quality Control of 2-Propoxyethanol.

What & apos;s in this drink? Classification and adulterant detection in Irish Whiskey samples using near infrared spectroscopy combined with chemometrics

BACKGROUND Near-infrared (NIR) spectroscopy coupled with principal component analysis (PCA) and partial least squares (PLS) regression was used to analyse a series of different Irish Whiskey samples in order to define their spectral profile and to assess the capability of the NIR method to identify samples based on their origin and storage (e.g. distiller, method of maturation). The ability of NIR spectroscopy to quantify the level of potential chemical adulterants was also investigated. Samples were spiked with 0.1%, 0.5%, 1.0%, 1.5% and 2.0% v/v of each adulterant (e.g. methanol, ethyl acetate, etc.) prior to NIR analysis. RESULTS The results of this study demonstrated the capability of NIR spectroscopy combined with PLS regression to classify the whiskey samples and to determine the level of adulteration. Moreover, the potential of NIR coupled with chemometric analysis as a rapid, portable, and non-destructive screening tool for quality control, traceability, and food/beverage adulteration for customs and other regulatory agencies, to mitigate beverage fraud was illustrated. CONCLUSION Given the non-specificity of the NIR technique, these positive preliminary results indicated that this method of analysis has the potential to be applied to identify the level of adulteration in distilled spirits. The rapid nature of the technique and lack of consumables or sample preparation required allows for a far more time and cost-effective analysis per sample. (c) 2021 Society of Chemical Industry.

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Synthetic Route of 2807-30-9, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 2807-30-9, Name is 2-Propoxyethanol, SMILES is CCCOCCO, belongs to alcohols-buliding-blocks compound. In a article, author is Bollen, Zoe, introduce new discover of the category.

Prior drinking motives predict alcohol consumption during the COVID-19 lockdown: A cross-sectional online survey among Belgian college students

The global outbreak of coronavirus disease 2019 (COVID-19) and the resulting lockdown measures have raised concerns regarding their effect on alcohol consumption. We investigated alcohol use during lockdown in a population of college students, usually characterized by social and heavy drinking. We also tested the predictive role of pre-lockdown drinking motives on alcohol consumption during lockdown. We collected data from 1951 French-speaking Belgian students during the lockdown period (April 1st – May 3rd, 2020) through a crosssectional online survey. Participants self-reported their daily alcohol consumption (1) during a typical week in normal circumstances (i.e., before lockdown), and (2) since lockdown onset. We also assessed drinking motives and severity of alcohol use before lockdown. Our findings showed that 68.2% of the sample reported a lower alcohol consumption during lockdown compared to before lockdown, 17.2% conversely reporting a higher consumption. Enhancement, social and coping motives were all associated with heavy drinking before lockdown. Enhancement and social motives predicted lower alcohol consumption during lockdown among heavy drinkers. Conversely, coping motives, as well as social motives among low drinkers, predicted higher consumption during lockdown. Conformity motives, as well as enhancement motives among low and moderate drinkers, did not predict alcohol consumption before or during lockdown. Overall, several pre-lockdown drinking motives reliably predicted alcohol consumption during lockdown and could thus be used to identify at-risk populations and to tailor intervention programs on alcohol misuse during sanitary crises.

Synthetic Route of 2807-30-9, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 2807-30-9 is helpful to your research.

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