Category: 26153-38-8

In 2019,Medicinal Chemistry Research included an article by Khan, Ayesha; Khan, Ajmal; Farooq, Umar; Taha, Muhammad; Shah, Syed Adnan Ali; Halim, Sobia Ahsan; Akram, Arfa; Khan, Mohammed Ziauddin; Jan, Abdul Khaliq; Al-Harrasi, Ahmed. Quality Control of 3,5-Dihydroxybenzaldehyde. The article was titled 《Oxindole-based chalcones: synthesis and their activity against glycation of proteins》. The information in the text is summarized as follows:

Diabetes mellitus, a metabolic disorder, is characterized by a substantial hyperglycemia. Prevalence of hyperglycemia for longer period of time can cause nonenzymic condensation of sugar in blood with amino group of protein and give rise to advanced glycation end products (AGEs). AGEs play a major role in the onset of late diabetic complications including diabetic retinopathy, nephropathy, neuropathy and cardiovascular diseases. There is a need to establish potential therapeutic regimens that can effectively inhibit the formation of AGEs. To this end a series of novel oxindole-based chalcones have been investigated for their antiglycation potential. Analogs 1 (IC50 = 155.22 ± 2.98 μM), 3 (IC50 = 195.95 ± 0.43 μM), 4 (IC50 = 289.47 ± 2.47 μM), 5 (IC50 = 222.44 ± 4.03 μM), 7 (IC50 = 251.27 ± 2.80 μM), and 20 (224.23 ± 1.93 μM) showed potent inhibitory activity against glycation compared to the reference Rutin (IC50 = 294.5 ± 1.5 μM). These results reveal that multiple hydroxyl substituents and their position on the aromatic ring play a key role in inhibitory effect due to their hydrogen bonding potential. The study also reveals the influence of substituents on the binding capabilities and in turn inhibitory potential of different analogs.3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Quality Control of 3,5-Dihydroxybenzaldehyde) was used in this study.

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Quality Control of 3,5-Dihydroxybenzaldehyde

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Triazole-containing terpyridines with terminal aurophilic groups and their complexes with RhIII for adsorption on the surface of gold》 was written by Salimova, I. O.; Berezina, A. V.; Moiseeva, A. A.; Zyk, N. V.; Beloglazkina, E. K.. Formula: C7H6O3This research focused ontriazole terpyridine aurophilic group preparation rhodium complexation; adsorption surface gold sulfur containing triazole terpyridine rhodium complex. The article conveys some information:

Authors synthesized substituted phenylterpyridines containing one or two terminal disulfide groups and triazole-containing fragments in the linker between the terpyridine and sulfur-containing functional groups, as well as coordination compounds of the obtained terpyridines with RhIII. The possibility of the ligands and complexes under study to be chemisorbed on the surface of gold electrodes with the formation of an Au-S bond was shown. In the part of experimental materials, we found many familiar compounds, such as 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Formula: C7H6O3)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Formula: C7H6O3

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Synthesis and characterization of nanoemulsion-mediated core crosslinked nanoparticles, and in vivo pharmacokinetics depending on the structural characteristics》 was written by Matsuno, Jun; Kanamaru, Takuma; Arai, Koichi; Tanaka, Rena; Lee, Ji Ha; Takahashi, Rintaro; Sakurai, Kazuo; Fujii, Shota. Safety of 3,5-Dihydroxybenzaldehyde And the article was included in Journal of Controlled Release in 2020. The article conveys some information:

For designing nanoparticles as drug carriers, a covalently crosslinked structure is necessary for the structural stability in vivo. In this study, we prepared core crosslinked nanoparticles through the formation of nanoemulsions stabilized by poly(ethylene glycol) (PEG)-bearing surfactants. The structural characteristics of these particles were carefully evaluated using small-angle scattering techniques including dynamic, static, x-ray, and neutron scattering. The particles demonstrated high stability even in vivo, with the suppression of premature drug release owing to the crosslinked structure. Interestingly, the ability to retain encapsulated mols. was dependent on the mol. weight of PEG in vivo, presumably due to the difference in the crowding d. of PEG chains at the outermost surface. This suggests that conferring structural stability via a core crosslinked structure is surely important, but we also need to consider controlling the crowding d. of the hydrophilic polymer chains in the particle shell when designing drug carriers. The experimental process involved the reaction of 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Safety of 3,5-Dihydroxybenzaldehyde)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Safety of 3,5-Dihydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
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In 2019,Journal of Molecular Liquids included an article by Kanth, Priyanka; Singh, Hemant Kumar; Kumar, Vijay; Singh, Sachin Kumar; Rao, D. S. Shankar; Prasad, S. Krishna; Singh, Bachcha. Recommanded Product: 26153-38-8. The article was titled 《Effect of regioisomerism on the self-assembly, photophysical and gelation behavior of aroylhydrazone based polycatenars: Synthesis and characterization》. The information in the text is summarized as follows:

The five series of aroylhydrazone based polycatenars differing from each other in number and position of alkoxy chains on one end of the core; keeping other end the same was reported. A systematic variation in the structures was carried out to understand the effect of position and chain length on the mesophase behavior. In the case of single alkoxy chain at 4-position, there was a transition from Smectic C to Smectic A mesophase during cooling and Smectic A to Smectic C transition in heating cycle in all the homologues except n = 6 & n = 8. In the case of two alkoxy chains at 3-, 5-positions, the compounds were non-mesogenic in nature. On changing the position of alkoxy chains from 3-, 5-positions to 3-, 4-positions, intermol. forces weaken and these compounds become liquid crystalline and show columnar rectangular mesophase resulting from the effect of regioisomerism. Moving on to the series with three alkoxy chains, it was observed that 2-, 3-, 4-trialkoxy substituted compounds exhibited columnar rectangular mesophase except lower chain length (n = 6 & 8) while 3-, 4-, 5-trialkoxy substituted aroylhydrazones showed columnar rectangular mesophase; except n = 10 which showed columnar oblique mesophase. Thus it was established that on increasing d. of alkoxy chains around one terminal, mesophase changes from smectic to columnar mesophase. Temperature dependent Raman studies confirmed the presence of intermol. hydrogen bonding. Further, effect of substitution pattern did not show much influence on the photophys. properties of the mesogenic series in solid and solution state. However, the non-mesogenic series showed a different absorption and emission transition from the mesogenic series in solid and solution state. Solid state fluorescence studies showed almost similar emission maxima in all the series. However, it was also noticed that non-mesogenic series showed maximum red shift emission maxima in solid state as compared to that of solution All the series showed good gelation properties with less than 1% CGC (wt%) suggesting the strong ability of mols. to form gel. These H-bonded liquid-crystalline gels have immense potential for applications in emissive displays. In the part of experimental materials, we found many familiar compounds, such as 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Recommanded Product: 26153-38-8)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Recommanded Product: 26153-38-8

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Alcohol – Wikipedia,
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Yayli, Nurettin; Kilic, Gozde; Celik, Gonca; Kahriman, Nuran; Kanbolat, Seyda; Bozdeveci, Arif; Karaoglu, Sengul Alpay; Aliyazicioglu, Rezzan; Sellitepe, Hasan Erdinc; Dogan, Inci Selin; Aydin, Ali published an article in 2021. The article was titled 《Synthesis of hydroxy benzoin/benzil analogs and investigation of their antioxidant, antimicrobial, enzyme inhibition, and cytotoxic activities》, and you may find the article in Turkish Journal of Chemistry.Product Details of 26153-38-8 The information in the text is summarized as follows:

In this study, hydroxy benzoin R1C(O)CH(OH)R2 (I) (R1 = 3-hydroxyphenyl, 4-hydroxyphenyl, 3,5-dihydroxyphenyl; R2 = Ph, 3-hydroxyphenyl, 3,5-dihydroxyphenyl; R1 = R2 = 3,5-dihydroxyphenyl), benzil R1C(O)C(O)R2, and benzoin/benzil-O-β;-D-glucosides R3C(O)CH(OH)R4 [R3 = (3-D-glucopyranosyl)phenyl, (4-D-glucopyranosyl)phenyl, (3,5-di-D-glucopyranosyl)phenyl, 3-hydroxyphenyl; R4 = Ph, 3-hydroxyphenyl, (3-D-glucopyranosyl)phenyl]/R3C(O)C(O)R5 (R5 = Ph, 3-hydroxyphenyl, 4-hydroxyphenyl) were synthesized to investigate their biol. activities. An efficient method for synthesizing hydroxy benzoin compounds (I) was prepared from four different benzaldehydes using an ultrasonic bath. Then, antioxidant (FRAP, CUPRAC, and DPPH), antimicrobial (3 G (-), 4/6 G (+), one tuberculosis and one fungus), and enzyme inhibition (acetylcholinesterase, butyrylcholine esterase, tyrosinase, α-amylase, and α- glucosidase) for the all synthesized compounds were evaluated. And also, four most active compounds (R1C(O)CH(OH)R2 (R1 = R2 = 3-hydroxyphenyl) (II), R1C(O)C(O)R2 (R1 = 3-hydroxyphenyl; R2 = 4-hydroxyphenyl), R3C(O)CH(OH)R4 [R3 = R4 = (3-D-glucopyranosyl)phenyl, 3-hydroxyphenyl], and R3C(O)C(O)R5 (R3 = (3-D-glucopyranosyl)phenyl; R5 = 4-hydroxyphenyl)) from each group were evaluated to the human cervical cancer cell line (HeLa) and anticancer screening tests against the human retinal normal cell line (RPE). Compound (II) showed HeLa and RPE cancer cell activities as much as cisplatin. The synthesized compounds were characterized by spectroscopic methods (NMR, FT-IR, UV, LC-QTOF-MS) and the ACD NMR program’s help. In the part of experimental materials, we found many familiar compounds, such as 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Product Details of 26153-38-8)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Product Details of 26153-38-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kanth, Priyanka; Shankar Rao, D. S.; Krishna Prasad, S.; Singh, Bachcha published an article in 2022. The article was titled 《Investigation of mesomorphic, photophysical and gelation behavior in aroylhydrazone based liquid crystals: Observation of mesophase crossover phenomena》, and you may find the article in Journal of Molecular Liquids.SDS of cas: 26153-38-8 The information in the text is summarized as follows:

Five series of substituted aroylhydrazones having two alkoxy chains at 3- and 5- positions at amide end of the mol. have been synthesized; wherein each series differ from each other in terms of number and position of alkoxy chains at imine end. The compounds of first series with the single alkoxy chain at 4-position at imine end self-assembled into columnar hexagonal mesophase. The lower homologues of the series with alkoxy chains at 3- and 5- positions at imine end showed a transition from columnar hexagonal to columnar rectangular mesophase in cooling cycle while the higher homologues exhibited columnar hexagonal mesophase. The series with alkoxy chains at 3- and 4- positions exhibited columnar rectangular mesophase. All the homologues of series with alkoxy chains at 2-, 3- and 4- positions showed a transition from columnar rectangular to columnar oblique mesophase in cooling cycle. The series with alkoxy chains at 3-, 4- and 5- positions exhibited transition in columnar hexagonal mesophase. The mesophase crossover from one columnar mesophase to the other was found to be dependent on the chain length as well as on the temperature during the self-assembly process in these mols. The substitution pattern showed an influence on the photophys. properties. The number and position of alkoxy chains played a critical role in the formation of gel in these mols. These liquid crystalline gelators have application potential in organic optoelectronic functional materials and devices. In the experimental materials used by the author, we found 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8SDS of cas: 26153-38-8)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.SDS of cas: 26153-38-8

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Alcohol – Wikipedia,
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Name: 3,5-DihydroxybenzaldehydeIn 2019 ,《A novel resveratrol derivative induces oxidative stress, G1 cell cycle arrest and premature senescence in A549 cells》 appeared in Latin American Journal of Pharmacy. The author of the article were Yang, Jie; Li, Jing; Qu, Xiao-Yu; Liu, Guo-Yun; Liu, Ren-Min. The article conveys some information:

Resveratrol has been reported to be a potential chemopreventive and anticancer agent. However, its poor bioavailability is being considered as a major obstacle in translating its effects in humans. Here, we report the synthesis and the anti-proliferative activities of fluorinated groups (CF3 and OCF3) substituted resveratrol derivatives A novel OCF3 substituted active derivative (A-3) owning the excellent stability and cell uptake ability in A549 cells, could improve the anti-proliferative activity (about 5 fold). In addition, A-3 could cause a clear block of cells in G1 phase (81.5%) and induce obvious premature senescence, via an apoptosis-independent mechanism; while resveratrol could cause an accumulation of cells in S phase (57.8%). Besides, A-3 treatment could cause an oxidized cellular environment in A549 cells. After reading the article, we found that the author used 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Name: 3,5-Dihydroxybenzaldehyde)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Name: 3,5-Dihydroxybenzaldehyde

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2018,Zhao, Jingming; Bachmann, Daniel G.; Lenz, Markus; Gillingham, Dennis G.; Ward, Thomas R. published 《An artificial metalloenzyme for carbene transfer based on a biotinylated dirhodium anchored within streptavidin》.Catalysis Science & Technology published the findings.Electric Literature of C7H6O3 The information in the text is summarized as follows:

Artificial metalloenzymes that incorporate a biotinylated dirhodium core embedded within engineered streptavidin (Sav hereafter) variants are reported. The resulting biohybrid catalyzes the carbene insertion in C-H bonds and olefins. Chem.- and genetic optimization allows to modulate the catalytic activity of the artificial metalloenzymes that are shown to be active in the periplasm of E. coli (up to 20 turnovers). The results came from multiple reactions, including the reaction of 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Electric Literature of C7H6O3)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Electric Literature of C7H6O3

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Alcohol – Wikipedia,
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In 2018,Liang, Dong-Dong; Wang, Mei-Xiang published 《Synthesis and Structure of Functionalized Homo Heteracalix[2]arene[2]triazines: Effect of All Heteroatom Bridges on Macrocyclic Conformation》.Journal of Organic Chemistry published the findings.Category: alcohols-buliding-blocks The information in the text is summarized as follows:

A number of unprecedented homo heteracalix[2]arene[2]triazines were synthesized by means of a fragment coupling approach. Two directional nucleophilic substitution reactions of N-Boc-protected 1,3-dihydrazobenzene with cyanuric acid chloride and 2-butoxy-4,6-dichloro-1,3,5-triazine led to hydrazo-linked trimers, which underwent an efficient macrocyclic condensation reaction with functionalized resorcinol derivatives to afford (NHNBoc)2,O2-calix[2]arene[2]triazine macrocycles, which contain a functional group either on the upper rim or the lower rim. The use of 1,3-phenylenediamines instead of resorcinol in the reaction produced (NR)2,(NHNBoc)2-calix[2]arene[2]triazines. Postmacrocyclization modifications such as a nucleophilic substitution reaction of chloro on triazine by amines and the removal of Boc from hydrazo moieties produced homo calix[2]arene[2]triazine derivatives In the solid state, (NHNR)2,O2-bridged calix[2]arene[2]triazines with and without a substituent on the upper rim position and (NMe)2,(NHNBoc)2-calix[2]arene[2]triazine adopted a typical partial cone conformation while the heavily twisted 1,3-alternate conformational structures were observed for both (NHNBoc)2,O2-calix[2]arene[2]triazines bearing a functional group on the lower rim position and (NH)2,(NHNBoc)2-calix[2]arene[2]triazine. In solution, all synthesized homo heteracalix[2]arene[2]triazines existed as the mixture of different macrocyclic conformers, which underwent slow interconversions at room temperature relative to the NMR time scale. In the experimental materials used by the author, we found 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Category: alcohols-buliding-blocks)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Food Research International included an article by Jeong, Gyeong Han; Park, Eui Kyun; Kim, Tae Hoon. Application of 26153-38-8. The article was titled 《Anti-diabetic effects of trans-resveratrol byproducts induced by plasma treatment》. The information in the text is summarized as follows:

Cold plasma processing has emerged a promising green technol. with great potential to improve the quality and microbial safety of various minimally processed foods and materials. Thus, the objective of this study was to evaluate the influence of a dielec. barrier discharge (DBD) treatment on principal trans-resveratrol (TR) in several food stuffs by spectroscopic (HPLC, NMR, MS) and biol. analyses. TR was dissolved in methanol and directly exposed to atm. non-thermal plasma field at 250 W for different durations (10, 20, 40, and 60 min), 40% relative humidity, and 25 °C. TR treated with plasma for 40 min showed greatly enhanced inhibitory activities for α-glucosidase and α-amylase than parent TR. Newly generated unusual compounds (1, 2) and known compounds (3-6) from plasma treated TR for 40 min were characterized using chromatog. and spectroscopic methods. The predominant reaction of TR induced by cold plasma followed by typical dimerization of products included methylene bridge formation and cyclization of TR. Among predominantly generated products, new compounds 1 and 2 showed more potent α-glucosidase and α-amylase inhibition capacities than parent TR. These results might be used to modify structures and enhance biol. property of TR during food processing using DBD plasma treatment. In the experiment, the researchers used 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Application of 26153-38-8)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Application of 26153-38-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts