Ilic, Ivan K.’s team published research in ChemSusChem in 2020 | CAS: 26153-38-8

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Application In Synthesis of 3,5-Dihydroxybenzaldehyde

《Interplay of Porosity, Wettability, and Redox Activity as Determining Factors for Lithium-Organic Electrochemical Energy Storage Using Biomoleculesã€?was written by Ilic, Ivan K.; Perovic, Milena; Liedel, Clemens. Application In Synthesis of 3,5-Dihydroxybenzaldehyde And the article was included in ChemSusChem in 2020. The article conveys some information:

Although several recent publications describe cathodes for electrochem. energy storage materials made from regrown biomass in aqueous electrolytes, their transfer to lithium-organic batteries is challenging. To gain a deeper understanding, we investigate the influences on charge storage in model systems based on biomass-derived, redox-active compounds and comparable structures. Hybrid materials from these model polymers and porous carbon are compared to determine precisely the causes of exceptional capacity in lithium-organic systems. Besides redox activity, particularly, wettability influences capacity of the composites greatly. Furthermore, in addition to biomass-derived mols. with catechol functionalities, which are described commonly as redox-active species in lithium-bio-organic systems, we further describe guaiacol groups as a promising alternative for the first time and compare the performance of the resp. compounds In the part of experimental materials, we found many familiar compounds, such as 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Application In Synthesis of 3,5-Dihydroxybenzaldehyde)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Application In Synthesis of 3,5-Dihydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Guan, Zhe’s team published research in Organic Letters in 2019 | CAS: 26153-38-8

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Name: 3,5-Dihydroxybenzaldehyde

Name: 3,5-DihydroxybenzaldehydeIn 2019 ,《Rhodium(III)-Catalyzed Intramolecular Olefin Hydroarylation of Aromatic Aldehydes Using a Transient Directing Groupã€?was published in Organic Letters. The article was written by Guan, Zhe; Chen, Siwei; Huang, Yue; Yao, Hequan. The article contains the following contents:

A Rh(III)-catalyzed intramol. olefin hydroarylation of aromatic aldehydes with a transient directing group has been described. The bidentate directing groups in situ generated from aromatic aldehydes and β-alanine could enable the subsequent C-H activation and hydroarylation with excellent site selectivities and high functional group compatibility. The further conversion of the aldehyde group showcased the broad application prospects of this methodol. In the experiment, the researchers used 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Name: 3,5-Dihydroxybenzaldehyde)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Name: 3,5-Dihydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ruggiero, Dafne’s team published research in Molecules in 2022 | CAS: 26153-38-8

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Recommanded Product: 26153-38-8

Recommanded Product: 26153-38-8In 2022 ,《Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Proteinã€?was published in Molecules. The article was written by Ruggiero, Dafne; Terracciano, Stefania; Lauro, Gianluigi; Pecoraro, Michela; Franceschelli, Silvia; Bifulco, Giuseppe; Bruno, Ines. The article contains the following contents:

The multidomain BAG3 protein is a member of the BAG (Bcl-2-associated athanogene) family of co-chaperones, involved in a wide range of protein-protein interactions crucial for many key cellular pathways, including autophagy, cytoskeletal dynamics, and apoptosis. Basal expression of BAG3 is elevated in several tumor cell lines, where it promotes cell survival signaling and apoptosis resistance through the interaction with many protein partners. In addition, its role as a key player of several hallmarks of cancer, such as metastasis, angiogenesis, autophagy activation, and apoptosis inhibition, has been established. Due to its involvement in malignant transformation, BAG3 has emerged as a potential and effective biol. target to control multiple cancer-related signaling pathways. Recently, by using a multidisciplinary approach we reported the first synthetic BAG3 modulator interfering with its BAG domain (BD), based on a 2,4-thiazolidinedione scaffold and endowed with significant anti-proliferative activity. Here, a further in silico-driven selection of a 2,4-thiazolidinedione-based compound was performed. Thanks to a straightforward synthesis, relevant binding affinity for the BAG3BD domain, and attractive biol. activities, this novel generation of compounds is of great interest for the development of further BAG3 binders, as well as for the elucidation of the biol. roles of this protein in tumors. Specifically, we found compound 6 as a new BAG3 modulator with a relevant antiproliferative effect on two different cancer cell lines (IC50: A375 = 19.36 μM; HeLa = 18.67 μM).3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Recommanded Product: 26153-38-8) was used in this study.

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Recommanded Product: 26153-38-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Chuan’s team published research in Organometallics in 2020 | CAS: 26153-38-8

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Product Details of 26153-38-8

《Butadiyne-Bridged (Porphinato)Zinc(II) Chromophores Assemble into Free-Standing Nanosheetsã€?was published in Organometallics in 2020. These research results belong to Liu, Chuan; Liu, Kaixuan; Mukhopadhyay, Arindam; Paulino, Victor; Bernard, Brianna; Olivier, Jean-Hubert. Product Details of 26153-38-8 The article mentions the following:

The mol. engineering of chromophores that enable the controlled and reliable formation of hierarchical solid-state architectures is at the forefront of developing hybrid semiconducting materials. While the rules and principles to assemble monomeric porphyrin-derived building blocks are well established, the aggregation of larger π-conjugated cores that feature electronically coupled porphyrin arrays was vastly underexplored. In the present contribution, the authors report the synthesis, spectroscopy, assembly, and solid-state properties of a class of butadiyne-bridged (porphinato)zinc(II) dimer chromophores. Spectroscopic study unravels the formation of aggregates in an aqueous medium, giving 2-dimensional objects that expand across microscale dimensions. Anal. of the height profile exploiting at. force microscopy indicates that one porphyrin dimer comprises the thickness of the solid-state hierarchical superstructure and underscores the promise of this approach to engineer solid-state platforms for (opto) electronic devices. Also, initiation of noncovalent interactions between building blocks by a chem. stimulus (pH) reveals that a nucleation-growth process governs the aggregation of the π-conjugated chromophores in an aqueous medium. This work provides tools to modulate the structure-function relations of supramol. architectures equipped with enticing optical properties. The experimental process involved the reaction of 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Product Details of 26153-38-8)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Product Details of 26153-38-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Yonghe’s team published research in Biomaterials in 2021 | CAS: 26153-38-8

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.SDS of cas: 26153-38-8

Zhang, Yonghe; Zhao, Ruibo; Liu, Jia; Kong, Hao; Zhang, Kebiao; Zhang, Yuan-Ning; Kong, Xiangdong; Zhang, Quan; Zhao, Yanli published their research in Biomaterials in 2021. The article was titled 《Hierarchical nano-to-molecular disassembly of boron dipyrromethene nanoparticles for enhanced tumor penetration and activatable photodynamic therapyã€?SDS of cas: 26153-38-8 The article contains the following contents:

The development of activatable photosensitizers (PSs) is of particular interest for achieving tumor photodynamic therapy (PDT) with minimal side effects. However, the in vivo applications of PSs are limited by complex physiol. and biol. delivery barriers. Herein, boron dipyrromethene (BDP)-based nanoparticles are developed through the self-assembly of a multifunctional “”one-for-all”” building block for enhanced tumor penetration and activatable PDT. The nanoparticles show excellent colloidal stability and long circulation lifetime in blood. Once they reach the tumor site, the first-stage size reduction occurs due to the hydrolysis of the Schiff base bond between polyethylene glycol and the cyclic Arg-Gly-Asp peptide in the acidic tumor microenvironment (pHâˆ?.5), facilitating tumor penetration and specific recognition by cancer cells overexpressing integrin ανβ3 receptors. Upon the endocytosis by cancer cells, the second-stage size reduction is triggered by more acidic pH in lysosomes (pHâˆ?.5). Importantly, the protonated diethylamino groups can block photoinduced electron transfer from the amine donor to the excited PSs and accelerate complete disassembly of the nanoparticles into single PS mol., with the recovery of the fluorescence and photoactivity for efficient PDT. This study presents a smart PS delivery strategy involving acidity-triggered hierarchical disassembly from the nano to mol. scale for precise tumor PDT. In addition to this study using 3,5-Dihydroxybenzaldehyde, there are many other studies that have used 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8SDS of cas: 26153-38-8) was used in this study.

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.SDS of cas: 26153-38-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

de Fatima, Angelo’s team published research in ACS Omega in 2019 | CAS: 26153-38-8

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Application of 26153-38-8

In 2019,ACS Omega included an article by de Fatima, Angelo; Docampo-Palacios, Maite; Alvarez-Hernandez, Anislay; Pasinetti, Giulio M.; Dixon, Richard A.. Application of 26153-38-8. The article was titled 《An Efficient Synthesis of Deoxyrhapontigenin-3-O-β-D-glucuronide, a Brain-Targeted Derivative of Dietary Resveratrol, and Its Precursor 4′-O-Me-Resveratrolã€? The information in the text is summarized as follows:

Bioactive dietary polyphenols have health benefits against a variety of disorders, but some benefits of polyphenols may be not directly related to them, but rather to their metabolites. Recently, we have identified the brain-available phenol glucuronide metabolite deoxyrhapontigenin-3-O- β-D-glucuronide (I) in perfused rat brains following sub-acute treatment with the stilbene resveratrol. However, the role of such a metabolite in the neuroprotective activity of resveratrol is not understood, in part due to the non-com. availability of I for performing biol. evaluation in animal models of Alzheimer’s disease or other neurol. disorders. Here, we describe a concise chem. synthesis of deoxyrhapontigenin-3-O- β-D-glucuronide and its precursor, 4-O-Me-resveratrol, accomplished in 4 and 6 steps with 74% and 21% overall yields, resp., starting from com. available 3,5-dihydroxybenzaldehyde. Pivotal reactions employed in the synthesis include the palladium-catalyzed C-C coupling between 3,5-di-tert-butyldiphenylsilyloxystyrene and p-iodoanisole in the presence of tributylamine and the acid-catalyzed glucuronidation between the trichloroacetimidate-activated glucuronic acid and 4-O-Me-resveratrol. In the experiment, the researchers used many compounds, for example, 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Application of 26153-38-8)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Application of 26153-38-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lesperance, Maxime’s team published research in Steroids in 2021 | CAS: 26153-38-8

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Application of 26153-38-8

Lesperance, Maxime; Roy, Jenny; Djiemeny Ngueta, Adrien; Maltais, Rene; Poirier, Donald published their research in Steroids in 2021. The article was titled 《Synthesis of 16β-derivatives of 3-(2-bromoethyl)-estra-1,3,5(10)-trien-17β-ol as inhibitors of 17β-HSD1 and/or steroid sulfatase for the treatment of estrogen-dependent diseasesã€?Application of 26153-38-8 The article contains the following contents:

17β-Hydroxysteroid dehydrogenase type 1 (17β-HSD1) and steroid sulfatase (STS) are involved in the synthesis of the most potent estrogen in the human body, estradiol (E2). These enzymes are known to play a pivotal role in the progression of estrogen-dependent diseases, such as breast cancer and endometriosis. Therefore, the inhibition of 17β-HSD1 and/or STS represents a promising avenue to modulate the growth of estrogen-dependent tumors or lesions. We recently established the key role of a bromoethyl side chain added at the C3-position of a 16β-carbamoyl-benzyl-E2 nucleus to covalently inhibit 17β-HSD1. To extend the structure-activity relationship study to the C16β-position of this new selective irreversible inhibitor (PBRM), we synthesized a series of analog compounds by changing the nature of the C16β-side chain but keeping the 2-bromoethyl group at position C3. We determined their 17β-HSD1 inhibitions in T-47D cells (transformation of E1 into E2), but we did not obtain a stronger 17β-HSD1 inhibitor than PBRM. Two compounds were found to be more likely to bind to the catalytic site and showed a promising but moderate inhibitory activity with estimated IC50 values of 0.5 and 0.7μM, resp. (about 10 times higher than PBRM). Interestingly, adding one or two sulfamate groups in the D-ring’s surroundings did not significantly decrease compounds’ potential to inhibit 17β-HSD1, but clearly improved their potential to inhibit STS. These results open the door to the development of a new family of steroid derivatives with dual (17β-HSD1 and STS) inhibiting actions. In addition to this study using 3,5-Dihydroxybenzaldehyde, there are many other studies that have used 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Application of 26153-38-8) was used in this study.

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Application of 26153-38-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cai, Pan’s team published research in Electrochimica Acta in 2018 | CAS: 26153-38-8

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.COA of Formula: C7H6O3

In 2018,Cai, Pan; Fan, Hongxian; Cao, Shuo; Qi, Jian; Zhang, Songmei; Li, Gang published 《Electrochemical conversion of corn stover lignin to biomass-based chemicals between Cu/Ni-Mo-Co cathode and Pb/PbO2 anode in alkali solutionã€?Electrochimica Acta published the findings.COA of Formula: C7H6O3 The information in the text is summarized as follows:

In this study, we put forward an effective method of producing renewable chems. from corn stover lignin with electrochem. redox between the Cu/Ni-Mo-Co cathode and Pb/PbO2 anode in sodium hydroxide solution Cyclic voltammetry tests and polarization curves were conducted to research the electrochem. oxidation performance of Pb/PbO2 anode and electrocatalytic hydrogenation of Cu/Ni-Mo-Co in lignin alkali solution Fourier transform IR spectroscopy (FTIR) and high performance liquid chromatog. (HPLC) were used to characterize the functional groups and mol. weight distribution of the lignin residue. By GC-MS anal., it confirmed that there were 24 kinds of compounds in degradation products of alkali corn stover lignin. In addition to this, some com. value chems. including trans-ferulic acid, vanillin, 3-hydroxy-4-methoxyphenyl-ethanone, syringaldehyde, acetosyringone and 4-methoxy-3-methyl-phenol were also observed The results came from multiple reactions, including the reaction of 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8COA of Formula: C7H6O3)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.COA of Formula: C7H6O3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sandeep, Anjamkudy’s team published research in ACS Omega in 2018 | CAS: 26153-38-8

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Quality Control of 3,5-Dihydroxybenzaldehyde

Quality Control of 3,5-DihydroxybenzaldehydeIn 2018 ,《Transforming a C3-Symmetrical Liquid Crystal to a π-Gelator by Alkoxy Chain Variationã€?was published in ACS Omega. The article was written by Sandeep, Anjamkudy; Praveen, Vakayil K.; Shankar Rao, D. S.; Krishna Prasad, S.; Ajayaghosh, Ayyappanpillai. The article contains the following contents:

Rational understanding of the structural features involving different noncovalent interactions is necessary to design a liquid crystal (LC) or an organogelator. Herein, we report the effect of the number and positions of alkoxy chains on the self-assembly induced phys. properties of a few π-conjugated mols. For this purpose, we designed and synthesized three C3-sym. mols. based on oligo(p-phenylenevinylene), C3OPV1-3. The self-assembly properties of these mols. are studied in the solid and solution states. All of the three mols. follow the isodesmic self-assembly pathway. Upon cooling from isotropic melt, C3OPV1 having nine alkoxy chains (-OC12H25) formed a columnar phase with two-dimensional rectangular lattice and retained the LC phase even at room temperature Interestingly, when one of the -OC12H25 groups from each of the end benzene rings is knocked out, the resultant mol., C3OPV2 lost the LC property, however, transformed as a gelator in toluene and n-decane. Surprisingly, when the -OC12H25 group from the middle position is removed, the resultant mol. C3OPV3 failed to form either the LC or the gel phases. In the experiment, the researchers used 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Quality Control of 3,5-Dihydroxybenzaldehyde)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Quality Control of 3,5-Dihydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kim, Hansol’s team published research in Dyes and Pigments in 2021 | CAS: 26153-38-8

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Category: alcohols-buliding-blocks

Kim, Hansol; Khazi, Mohammed Iqbal; Kim, Jong-Man published an article in 2021. The article was titled 《Preparation and colorimetric response of an aldehyde-functionalized macrocyclic diacetylene-derived polydiacetyleneã€? and you may find the article in Dyes and Pigments.Category: alcohols-buliding-blocks The information in the text is summarized as follows:

Stimulus-responsive colorimetric materials have found great utility in a variety of fields including anticounterfeiting, display and sensor technologies. Herein, the authors describe a colorimetric polydiacetylene (PDA) that is generated by polymerization of the aldehyde-functionalized macrocyclic diacetylene, MCDA-CHO. UV irradiation of self-assembled MCDA-CHO generates a blue-color PDA, which undergoes a sequential blue-purple-brown-orange color change upon heating. Interestingly, the PDA displays a remarkably high temperature reversible thermochromism between 30 (blue) and 180° (reddish-brown). In addition to displaying reversible thermochromism, polymerized MCDA-CHO can be employed for colorimetric differentiation between aromatic and aliphatic primary amines. Accordingly, a blue-to-reddish brown color change takes place when the PDA is exposed to primary aniline derivatives while no color change occurs in the presence of aliphatic primary amines. IR spectroscopic anal. confirms that this colorimetric selectivity is a consequence of the facile formation of imine groups through reactions of the aldehyde moieties in the PDA with anilines. The results came from multiple reactions, including the reaction of 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Category: alcohols-buliding-blocks)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts