Category: 2615-15-8

2615-15-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 2615-15-8, name is 3,6,9,12,15-Pentaoxaheptadecane-1,17-diol. This compound has unique chemical properties. The synthetic route is as follows.

Step 1.In a 50 mL three-necked flask, add TsCl (6.05 g, 31.9 mmol),Hexaethylene glycol (3.81 g, 12.8 mmol), a catalytic amount of 4-dimethylaminopyridine (20 mg) and 20 mL of CH2Cl2,Under an ice-salt bath, triethylamine (6.55 g, 64.8 mmol) was added dropwise using a constant pressure dropping funnel.After stirring at room temperature for 12h, the reaction was stopped and washed with 1M HCl solution (30mL ¡Á 3).Wash with saturated sodium bicarbonate solution (30 mL ¡Á 3), wash with saturated brine (30 mL ¡Á 3), and dry with anhydrous sodium sulfate. Filter and spin dry.Column chromatography separation: CH2Cl2 ? CH2Cl2: EA = 1: 1, red compound A was obtained as a viscous liquid.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 2615-15-8, 3,6,9,12,15-Pentaoxaheptadecane-1,17-diol.

Reference:
Patent; Changzhou University; Xiao Tangxin; Zhou Ling; Wu Kehui; Li Zhengyi; Sun Xiaoqiang; (6 pag.)CN110372682; (2019); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

2615-15-8, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2615-15-8, name is 3,6,9,12,15-Pentaoxaheptadecane-1,17-diol. This compound has unique chemical properties. The synthetic route is as follows.

Hexaethylene glycol (1.41 g, 5 mmol) Was dissolved in triethylamine (3.5 mL, 25 mmol) And dry Dichloromethane (100 mL), ice bath, Slowly add p-toluenesulfonyl chloride (2.4 g, 15 mmol) Stir at room temperature for 24 hours. TLC (EtOAc) to complete the reaction. Dilute dichloromethane (200 mL) was added, followed by 1 MHC1 , Saturated NaHC03, and saturated NaCl, and the organic phase was dried with anhydrous Na2SO4. After removing Na2S04 by filtration, the organic phase was evaporated to dryness under reduced pressure The mixture was purified by sonar column chromatography (2: l EtOAc / hexanes) to give the product as a colorless oil (2.62 g, 90%)

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 2615-15-8, 3,6,9,12,15-Pentaoxaheptadecane-1,17-diol.

Reference:
Patent; Institute of Microbiology of the Chinese Academy of Sciences (IMCAS); Li, Xuebing; Zhang, Zhenxing; (21 pag.)CN106589014; (2017); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

2615-15-8, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 2615-15-8 as follows.

(a) 1,17-Diazido-3,6,9,12,15-pentaoxaheptadecane A solution of dry hexaethylene glycol (25 g, 88 mmol) and methanesulfonyl chloride (22.3 g, 195 mmol) in dry THF (125 mL) was kept under argon and cooled to 0 C. in an ice/water bath. A solution of triethylamine (19.7 g, 195 mmol) in dry THF (25 mL) was added dropwise over 45 min. After 1 hr the cooling bath was removed and the reaction was stirred for another for 4 hrs. Water (55 mL) was then added to the mixture, followed by sodium hydrogencarbonate (5.3 g, to pH 8) and sodium azide (12.7 g, 195 mmol). THF was removed by distillation and the aqueous solution was refluxed for 24 h (two layers were formed). The mixture was cooled, ether (100 mL) was added and the aqueous phase was saturated with sodium chloride. The phases were separated and the aqueous phase was extracted with ether (4*50 mL). The combined organic phases were washed with brine (2*50 mL) and dried (MgSO4). Filtration and evaporation of the solvent gave a yellow oil 26 g (89%). The product was used in the next step without further purification.

The chemical industry reduces the impact on the environment during synthesis 2615-15-8, I believe this compound will play a more active role in future production and life.

Reference:
Patent; GE HEALTHCARE LIMITED; BARNETT, DAVID JONATHAN; HENRIKSEN, INGRID; CONSTANTINOU, MARIA; PETTITT, ROGER PAUL; US2013/209358; (2013); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts