Category: 2451-01-6

Evaluation of usage three natural extracts applied to three commercial wood species against five common molds was written by Salem, Mohamed Z. M.;Zidan, Yassin E.;El Hadidi, Nesrin M. N.;Mansour, Maisa M. A.;Abo Elgat, Wael A. A.. And the article was included in International Biodeterioration & Biodegradation in 2016.Recommanded Product: 2451-01-6 This article mentions the following:

Natural extracts have become of high interest in the past ten years for their inhibiting the growth of molds over wood and wood products surfaces in service or during the storage of building materials. In the present study, the antifungal effects of three natural extracts applied to three woods against five common molds were assessed. The growth of fungal hyphae of Alternaria alternata, Fusarium subglutinans, Chaetomium globosum, Aspergillus niger, and Trichoderma viride on the surfaces of Pinus sylvestris, Pinus rigida and Fagus sylvatica woods treated with extracts of Pinusrigida (heartwood), Eucalyptus camaldulensis (leaves) and Costus speciosus (rhizomes) was visually estimated GC/MS and FTIR analyses were used to identify the chem. constituents and the functional groups of extracts a-terpineol (24.91%), borneol (10.95%), terpin hydrate (9.60%), D-fenchyl alc. (5.99%), and limonene glycol (5.05%), which are the main constituents of P. rigida heartwood methanol extract The main chem. compounds of methanol extract from Eucalyptuscamaldulensis leaves were spathulenol (18.89%), cryptone (5.79%), 4,6,6-trimethyl-2-(3-methylbuta-1,3-dienyl)-3-oxatricyclo[5.1.0.0(2,4)]octane (5.79%), (3,3-dimethylcyclohexylidene)-(E)-acetaldehyde (5.57%), and ascaridole (4.32%). The main constituents identified in the distilled water extract from Costusspeciosus rhizomes were meso-erythritol (12.21%), methyl-2-methyl-1,3-oxothiolan-2-yl-ketone (11.61%), (all-Z)-5,8,11,14,17-eicosapentaenoic acid-Me ester (9.74%), diosgenin (5.07%), 2-ethyl-3-hydroxy-4H-pyran-4-one (4.43%), 3′,4′,7-trimethylquercetin (3.17%), and digitoxin (2.77%). Wood specimens treated at the level of 2% concentration of P. rigida heartwood extract observed good inhibition to the mold growth under laboratory conditions. These findings support the potential use of natural extracts for natural wood protection against mold infestation for surface treatment of wood. The results indicate that wood extracts may be useful for reducing the incidence of mold on wood products, but none of the materials evaluated completely inhibited the test fungi. These extracts may provide a useful value-added application for byproducts of lumber production from these species. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Recommanded Product: 2451-01-6).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Recommanded Product: 2451-01-6

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Changes of the particle size in suspension type medicines was written by Mersich-Vetsey-Kormendi, Agnes. And the article was included in Gyogyszereszet in 1972.Electric Literature of C10H22O3 This article mentions the following:

Medicinal suspensions containing terpine hydrate, norcaine, salicylamide, Bi salicylate in aqueous medium, norcaine, Na salicylate, amidopyrine, caffeine and Na benzoate, phenobarbital and Na noramidopyrine methanesulfonate in soft or solid fatty medium were examined for stability based on the initial parameters. No generalization could be made, hence the elaboration of new formulations of medicinal suspensions, the optimum conditions should be determined individually. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Electric Literature of C10H22O3).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Electric Literature of C10H22O3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Fractional hydrodistillation of Citronella (Cymbopogon winterianus Jowitt) was written by Rout, P. K.;Jena, K. S.;Rao, Y. R.. And the article was included in Fafai Journal in 2001.Safety of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate This article mentions the following:

Fractional hydro-distillation of Citronella Grass (C. winterianus Jowitt) and anal. of the decanted oil fractions showed that citronellal-rich fractions and sesquiterpenoid-rich fractions can be separated at the hydrodistillation stage itself. About 6% essential oil is lost in the aqueous layer. Further, 4 constituents, 6-methyl-5-hepten-2-one, benzyl alc., 2-[2-hydroxy-2-propyl]-5-menthylcyclohexanol and terpin hydrate present in significant quantities in the aqueous layer are not detected in any of the decanted oil fractions. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Safety of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Safety of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chemotype of Litsea cubeba Essential Oil and Its Bioactivity was written by Abdul Hammid, Syaliza;Ahmad, Fasihuddin. And the article was included in Natural Product Communications in 2015.Quality Control of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate This article mentions the following:

The essential oils from different parts of Litsea cubeba, collected from the highlands of Sarawak, were isolated and their chem. compositions analyzed. This study demonstrated significant variations in the chem. compositions and the chem. profiles of the volatiles and could provide valuable supplementary information on the geog. variations of the species. The fruit essential oil was dominated by citronellal, d-limonene and citronellol, while the leaf oil was high in eucalyptol and α-terpineol. High concentrations of citronellal and citronellol in both the root and bark oils were identified. In the stem, the oil was dominated by eucalyptol, d-limonene and α-terpineol. The activity of the oils against brine shrimp larvae, bacteria, yeast and fungi was determined The oils were toxic against brine shrimp larvae with LC₅₀ values ranging from 25.1 – 30.9μL/mL. The oils also demonstrated a wide spectrum of inhibition against microorganisms with inhibition zones between 19.5 – 46.7 mm against Gram-pos. bacteria and 10.5 – 90.0 mm against yeast and fungi. However, the oils were not active against Gram-neg. bacteria. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Quality Control of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Quality Control of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Composition of four essential oils obtained from plants from Cameroon, and their bactericidal and bacteriostatic activity against Listeria monocytogenes, Salmonella enteritidis and Staphylococcus aureus was written by Gardini, Fausto;Belletti, Nicoletta;Ndagijimana, Maurice;Guerzoni, Maria E.;Tchoumbougnang, Francois;Zollo, Paul H. Amvam;Micci, Claudio;Lanciotti, Rosalba;Sado Kamdem, Sylvain L.. And the article was included in African Journal of Microbiology Research in 2009.Safety of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate This article mentions the following:

The composition of four essential oils (EOs) extracted by hydrodistillation from plants of common use in Cameroon (Curcuma longa, Xylopia aethiopica, Zanthoxylum leprieurii L., Zanthoxylum xanthoxyloides) was assessed by gas chromatog.-mass. Their bactericidal and bacteriostatic activity was tested in vitro against three food borne pathogenic bacteria: Listeria monocytogenes, Salmonella enteritidis and Staphylococcus aureus. The bacteriostatic activities of this EOs on food borne bacteria were assessed in vitro through optical d. measurements. The minimal bactericidal concentrations (MBC) were determined in broth combined with a spot plating method. Z. xanthoxyloides and Z. leprieurii showed a similar composition, with a prevalence of oxygenated monoterpenes (about 58%). The EO of Z. xanthoxyloides was the most effective against the microorganisms tested. Its higher concentration of geraniol could be linked to this higher activity. In almost all cases, the MBC was higher than the maximum concentration tested (3000 ppm). Notwithstanding their low bactericidal effect, the EOs studied showed interesting inhibiting activities against the tested food borne pathogens. S. enteritidis was the most resistant to the bacteriostatic effect of the four EOs. The knowledge of the antimicrobial potential of local plant EOs used in developing countries could help in their choice and their use to improve food safety and shelf-life. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Safety of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Safety of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Protocol for the analyzing of terpin hydrate in a multi-component sugar coated tablet named Pectol D by GC was written by Ha, Minh Hien;Tran, Thi Bich Ha;Bo, Nguyen Thuy Duoung. And the article was included in Tap Chi Duoc Hoc in 2006.Name: rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate This article mentions the following:

Anal. of terpin hydrate in multi-component sugar coated tablets namely Pectol D by UV-Vis method was not possible due to the interference of excipients. Alternatively, a GC method using a packed column of 50% di-Me 50% di-Ph polysiloxane was suggested and validated based on ASEAN Guidelines for Validation of Anal. Procedures. The method was proved to be accurate, precise and sufficiently selective. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Name: rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Name: rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Structure and activity of the constituents of the flotation pine oils was written by Desalbres, L.. And the article was included in Rev. ind. minérale in 1956.Quality Control of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate This article mentions the following:

Pine oil is widely used in flotation processes. The foaming activity of a pine oil is bound to the presence of terpenic alcs. in C₁₀H₁₈O. The average chem. analysis of pine oils gives: tertiary alcs.:terpineols 60-70%, secondary alcs.:borneol-fenchol 15-20%, hydrocarbons 10-20%. The structural diagrams of these and their subgroups are given. The tertiary hydroxyl group is the most active; then the secondary groups and ether oxides; the ethylenic hydrocarbons have no activity. No exact relation exists between the solubility and the foaming power within a given group. At 15°, 2.1 g. of terpineol is needed to saturate 1 g. of water, 1 g. of menthanol, 0.44 g. of borneol; menthanol foams the most. The surface activity of a mol. has no relation to its foaming activity: a saturated menthanol sol at 15° has a surface tension of 38 dynes/cm., a saturated terpineol sol of 39 dynes/cm. For the same concentration, the menthanol gives a much greater volume of foam. It is the same with the hydrocarbons: saturated cymene sol has a surface tension of 52, of terpinene 51 dynes/cm., but the cymene is nonfoaming while terpinene is. The foaming activity of a mol. seems to be connected therefore to an assembly of characters of a functional and structural order. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Quality Control of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Quality Control of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Assay of terpin hydrate and codeine elixir by gas chromatography was written by Wasselman, Harold J.. And the article was included in Journal of Pharmaceutical Sciences in 1968.Reference of 2451-01-6 This article mentions the following:

Terpin hydrate and codeine after extraction from the elixir are separated and determined with the aid of two internal standards and the use of temperature-programmed gas chromatog. Using the same method, elixir of terpin hydrate can also be determined A precision and accuracy study for both elixirs is included. 25 references. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Reference of 2451-01-6).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Reference of 2451-01-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

CAESAR models for developmental toxicity was written by Cassano, Antonio;Manganaro, Alberto;Martin, Todd;Young, Douglas;Piclin, Nadege;Pintore, Marco;Bigoni, Davide;Benfenati, Emilio. And the article was included in Chemistry Central Journal in 2010.Synthetic Route of C10H22O3 This article mentions the following:

Background: The new REACH legislation requires assessment of a large number of chems. in the European market for several endpoints. Developmental toxicity is one of the most difficult endpoints to assess, on account of the complexity, length and costs of experiments Following the encouragement of QSAR (in silico) methods provided in the REACH itself, the CAESAR project has developed several models. Results: Two QSAR models for developmental toxicity have been developed, using different statistical/math. methods. Both models performed well. The first makes a classification based on a random forest algorithm, while the second is based on an adaptive fuzzy partition algorithm. The first model has been implemented and inserted into the CAESAR online application, which is java-based software that allows everyone to freely use the models. Conclusions: The CAESAR QSAR models have been developed with the aim to minimize false negatives in order to make them more usable for REACH. The CAESAR online application ensures that both industry and regulators can easily access and use the developmental toxicity model (as well as the models for the other four endpoints). In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Synthetic Route of C10H22O3).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Synthetic Route of C10H22O3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Proposals for the pharmacopeia: opium and its preparations was written by Carlassare, Mario. And the article was included in Bollettino Chimico Farmaceutico in 1982.SDS of cas: 2451-01-6 This article mentions the following:

Changes in the Italian Pharmacopeia methods for anal. of opium, laudanum, and tablets containing K guaiacolsulfonate  [1321-14-8], Na benzoate  [532-32-1], terpin hydrate  [2451-01-6], and Dover’s powder (morphine  [57-27-2], emetine  [483-18-1], and camphor) are proposed. Qual. color tests for meconic acid  [497-59-6] and morphine in opium are described, together with a titrimetric method for measuring morphine and a simple TLC method for estimating morphine, papaverine  [58-74-2], and codeine  [76-57-3] in opium are given. For laudanum, color tests for morphine and meconic acid, and TLC estimation and determination of morphine (as for opium) are proposed. For the tablets, color tests are given for identification of K, benzoate, guaiacolsulfonate, terpin, and morphine, and a flame test for Na. A TLC method for morphine, codeine, papaverine and emetine, and quant. methods for Na benzoate (titrimetry) and K guaiacolsulfonate (colorimetry) are included for the tablets. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6SDS of cas: 2451-01-6).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.SDS of cas: 2451-01-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts