Category: 23351-09-9

Xia, Shanghua published the artcileCopper-Catalyzed Hydroxylation of (Hetero)aryl Halides under Mild Conditions, Name: 4-(1H-Pyrrol-1-yl)phenol, the publication is Journal of the American Chemical Society (2016), 138(41), 13493-13496, database is CAplus and MEDLINE.

In the presence of Cu(acac)₂ and N,N’-bis(4-hydroxyl-2,6-dimethylphenyl)oxalamide, aryl and heteroaryl chlorides, bromides, and iodides underwent hydroxylation reactions in DMSO/H₂O to yield phenols and aryl and heteroaryl alcs. A wide range of aryl and heteroaryl chlorides bearing either electron-donating or electron-withdrawing groups underwent hydroxylation at 130 °C to provide the corresponding phenols and hydroxylated heteroarenes in 52-96% yields. When more reactive aryl and heteroaryl bromides and iodides were employed, the hydroxylation reactions could be performed at 80° and 60°, resp., using 0.5 mol% of Cu(acac)₂.

Journal of the American Chemical Society published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C12H14BNO2, Name: 4-(1H-Pyrrol-1-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kiskan, Baris published the artcileSynthesis and characterization of pyrrole and thiophene functional polystyrenes via “click chemistry”, Safety of 4-(1H-Pyrrol-1-yl)phenol, the publication is Polymer Bulletin (Heidelberg, Germany) (2011), 67(4), 609-621, database is CAplus.

Novel side-chain pyrrole or thiophene functional polystyrenes (PS-Py and PS-Th) were synthesized by using “click chem.” strategy. First, approx. 40% of chloro groups of poly(styrene-co-chloromethylstyrene) P(S-co-CMS), prepared by nitroxide mediated radical polymerization (NMRP), were converted to azido groups by using NaN₃ in N,N-dimethylformamide. Propargyl pyrrole was prepared by etherification of 4-(1H-pyrrol-1-yl)phenol prepared by Clauson-Kaas reaction using propargylbromide. Propargyl thiophene was synthesized by heterogeneous esterification reaction between 3-thiophenecarboxylic acid and propargylbromide. Finally, azido-functionalized polystyrene was coupled to these propargyl functional heterocyclics with high efficiency by click chem. The intermediates at various stages and final polymers were characterized by spectral anal. and cyclic voltammetry.

Polymer Bulletin (Heidelberg, Germany) published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Safety of 4-(1H-Pyrrol-1-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Mengozzi, Luca published the artcilePhenoxyaluminum(salophen) Scaffolds: Synthesis, Electrochemical Properties, and Self-Assembly at Surfaces of Multifunctional Systems, Recommanded Product: 4-(1H-Pyrrol-1-yl)phenol, the publication is Chemistry – A European Journal (2018), 24(46), 11954-11960, database is CAplus and MEDLINE.

Salophens and Salens are Schiff bases generated through the condensation of two equivalent of salicylaldehyde with either 1,2-phenylenediamines or aliphatic diamines, resp. Both ligands have been extensively exploited as key building blocks in coordination chem. and catalysis. In particular, their metal complexes have been widely used for various catalytic transformations with high yield and selectivity. Through the modification of the phenol unit it is possible to tune the steric hindrance and electronic properties of Salophen and Salen. The introduction of long aliphatic chains in salicylaldehydes can be used to promote their self-assembly into ordered supramol. structures on solid surfaces. Herein, the authors report a novel method towards the facile synthesis of robust and air-stable [Al(Salophen)] derivatives capable of undergoing spontaneous self-assembly at the graphite/solution interface forming highly-ordered nanopatterns. The new synthetic approach relies on the use of [MeAl^III(Salophen)] as a building unit to introduce, via a simple acid/base reaction with functionalized acidic phenol derivatives, selected frameworks integrating multiple functions for efficient surface decoration. STM imaging at the solid/liquid interface made it possible to monitor the formation of ordered supramol. structures. In addition, the redox properties of the Salophen derivatives functionalized with ferrocene units in solution and on surface were unraveled by cyclic voltammetry. The use of a five-coordinate aluminum alkyl Salophen precursor enables the tailoring of new Salophen mols. capable of undergoing controlled self-assembly on HOPG, and thereby it can be exploited to introduce multiple functionalities with subnanometer precision at surfaces, ultimately forming ordered functional patterns.

Chemistry – A European Journal published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Recommanded Product: 4-(1H-Pyrrol-1-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chams, Amani published the artcileDirect growth of polymer brushes from an electrodeposited conducting poly(dithienylpyrrole) layer functionalized with ATRP initiating moieties, Synthetic Route of 23351-09-9, the publication is Journal of Electroanalytical Chemistry (2013), 20-30, database is CAplus.

A new strategy for growing polymer brushes using surface-initiated atom transfer radical polymerization (SI-ATRP) from a thin functionalized conducting-polymer layer is reported. Three new heterocyclic monomers based on thiophene and/or pyrrole bearing an ATRP-initiator have been synthesized. Electrochem. behavior and electrodeposition of these monomers was carried out by both potentiodynamic (CV) and potentiostatic (CA) methods. Remarkably, the use of a tricyclic (2,5-dithienyl)pyrrole-based monomer allowed the formation of a conducting film at a relatively low oxidation potential (onset ∼0.65 V/SCE). Electroactivity characterization showed that conducting, stable and adherent thin polymer layer was formed. The charge-transfer agent was subsequently engaged in SI-ATRP to grow polymethacrylate brushes directly from the conducting functionalized surface. Both the functionalized conducting polymer layer and the resulting tethered polymer brushes were characterized using XPS and SEM (SEM). This study confirms that polymethacrylate brushes can efficiently grow directly from a functionalized conducting-polymer thin layer by using a conventional SI-ATRP procedure.

Journal of Electroanalytical Chemistry published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Synthetic Route of 23351-09-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Soon, Geok Hong published the artcileSynthesis, co-polymerization, and electrochemical evaluation of novel ferrocene-pyrrole derivatives, Computed Properties of 23351-09-9, the publication is Analytical Letters (2011), 44(11), 1976-1995, database is CAplus.

New ferrocene derivatives, (6-(4-(1H-pyrrol-1-yl)phenoxy)hexyl) ferrocene (1) and ((4-(1H-pyrrol-1-yl)phenoxy)carbonyl) ferrocene (2) were synthesized, characterized, and electrochem. evaluated as redox active films formed via anodic oxidation with pyrrole. Thin film studies were conducted and films formed from both compounds resulted in a stable Fe^II/III redox couple with E^o = 0.035 V and 0.365 V vs. Ag/Ag⁺ for (1) and (2), resp. Both potential sweeping and chronocoulometry were employed for film formation with the former resulting in controllable, reproducible film deposition. Growth conditions and solution concentrations were varied to assess influence on electrochem. behavior. Surface coverage was of the order 10^-8-10^-9 mol cm^-2, surface confined behavior (i_p vs. ν) was evident up to 0.2 V s^-1 with semi-infinite diffusion (i_p vs. ν^1/2) dominating at higher scan rates. Laviron theory was employed where possible for the determination of electron transfer coefficient and rate constants

Analytical Letters published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C11H14O2, Computed Properties of 23351-09-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Naeimi, Hossein published the artcileEfficient and green synthesis of N-aryl pyrroles catalyzed by ionic liquid [H-NMP] [HSO₄] in Water at room temperature, Application of 4-(1H-Pyrrol-1-yl)phenol, the publication is Journal of the Chinese Chemical Society (Weinheim, Germany) (2014), 61(10), 1127-1132, database is CAplus.

A suitable and efficient method for the synthesis of N-aryl pyrroles I [Ar = C₆H₅, 4-CH₃C₆H₄, 4-OHC₆H₄, etc.] by using 2,5-dimethoxy THF and several primary aromatic amines in the presence of the catalytic amount of [H-NMP][HSO₄] under room temperature was described. This method has the advantages such as; easy reaction workup, absolutely separated of catalyst from the reaction mixture and smoothly recyclability of catalyst. The compound I were obtained as desired products in excellent yields and short reaction times via green and one-pot procedure.

Journal of the Chinese Chemical Society (Weinheim, Germany) published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Application of 4-(1H-Pyrrol-1-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Naeimi, Hossein published the artcileFunctionalized multi-walled carbon nanotubes as an efficient reusable heterogeneous catalyst for green synthesis of N-substituted pyrroles in water, Computed Properties of 23351-09-9, the publication is RSC Advances (2015), 5(93), 76221-76228, database is CAplus.

In this protocol, the functionalization of multiwalled carbon nanotubes (MWCNTs) was carried out and the resulting sulfonated MWCNTs were characterized by FT-IR, XRD, SEM, BET, EDX, XPS and Raman spectroscopy that are each discussed sep. in the text. Then, the MWCNT-SO₃H composite was applied as an efficient, recyclable heterogeneous catalyst for the synthesis of N-substituted pyrroles via the reaction of 2,5-dimethoxy THF with primary amines under clean and mild conditions. In this reaction, the N-substituted pyrroles were obtained as beneficial and significant products in short reaction times (30-65 min) and good to excellent yields (40-92%) with high purity. The products were obtained through a simple work up procedure and characterized by FT-IR, ¹H NMR and ¹³C NMR. After the end of the reaction, the nanocatalyst was recovered and reused several times without efficient loss of its activity for the preparation of N-substituted pyrroles.

RSC Advances published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Computed Properties of 23351-09-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Naeimi, Hossein published the artcileFacile sonochemical heterocyclization of 2,5-dimethoxy tetrahydrofuran with primary amines using sulfonated MWCNTs as a recyclable catalyst in aqueous media, Recommanded Product: 4-(1H-Pyrrol-1-yl)phenol, the publication is Green Chemistry Letters and Reviews (2017), 10(4), 412-419, database is CAplus.

A set of N-substituted pyrrole derivatives was designed and synthesized using sulfonated multi-walled carbon nanotubes as a recyclable heterogeneous catalyst under ultrasound irradiation This reaction was carried out between 2,5-dimethoxy THF and primary amines in water under green conditions. This method has some advantages such as: short reaction times, excellent product yields, simplicity of the procedure, easy work-up and high purity of products.

Green Chemistry Letters and Reviews published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Recommanded Product: 4-(1H-Pyrrol-1-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ertas, Merve published the artcileSynthesis and characterization of conducting copolymers of succinic acid bis-(4-pyrrol-1-yl-phenyl) ester and their electrochromic properties, Computed Properties of 23351-09-9, the publication is Synthetic Metals (2004), 143(1), 49-58, database is CAplus.

A new dipyrrolyl monomer was synthesized via the reaction between 4-pyrrol-1-yl phenol and butanedioyl dichloride. The electrochem. behavior of this monomer, succinic acid bis(4-pyrrol-1-yl-phenyl) ester (SM) was studied. Homopolymerization was achieved by chem. and constant current electrolysis methods. Copolymerization of SM with thiophene was performed by constant potential electrolysis in acetonitrile-tetrabutylammonium tetrafluoroborate (TBAFB) and dichloromethane-TBAFB, solvent-electrolyte couples. The chem. structure was investigated by NMR spectroscopy and Fourier-transform IR spectroscopy. Thermal analyses were studied by differential scanning calorimetry and thermal gravimetry anal. The morphologies of the films were examined by SEM. Conductivities of the samples were measured using a four-probe technique. Moreover, the spectroelectrochem. and electrochromic properties of SM/thiophene copolymer were investigated using a UV-visible spectrophotometer and colorimetry.

Synthetic Metals published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Computed Properties of 23351-09-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lim, Soobin published the artcileCobalt-Catalyzed Defluorosilylation of Aryl Fluorides via Grignard Reagent Formation, Synthetic Route of 23351-09-9, the publication is Organic Letters (2020), 22(18), 7387-7392, database is CAplus and MEDLINE.

Transition-metal-catalyzed transformations of the C-F bond not only tackle an interesting problem of challenging bond activation but also offer new synthetic strategies where the relatively inert C-F bond is converted to versatile functional groups. Herein the authors report a practical Co-catalyzed silylation of aryl fluorides that uses a cheap electrophilic Si source with Mg. This method is compatible with various Si sources and can be operated under aerobic conditions. Mechanistic studies support the in situ formation of a Grignard reagent, which is captured by the electrophilic Si source.

Organic Letters published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Synthetic Route of 23351-09-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts