Category: 2240-88-2

Haraguchi, Kazutoshi published the artcileNew Aqueous Solutions with Lower Viscosities than Water, Recommanded Product: 3,3,3-Trifluoropropan-1-ol, the publication is Bulletin of the Chemical Society of Japan (2021), 94(4), 1185-1191, database is CAplus.

Liquid water exhibits many anomalous phys. properties because of its unique structure and hydrogen bonding networks, which were mostly uncovered at the beginning of the 20th century. Because of its interesting properties and microstructures under various conditions and in aqueous solutions, understanding the behavior of water is important, but remains scientifically challenging. Regarding the viscosity of aqueous solutions, despite the discovery 147 years ago that very small amounts of certain salts decrease the viscosity of water slightly, there has been no significant progress to date. Herein, we report new aqueous solutions, with low additive fractions and much lower viscosities than pure water, which exhibit unique viscosity-composition curves. The findings should spark renewed interest in scientific research on water, which may greatly impact numerous industries.

Bulletin of the Chemical Society of Japan published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, Recommanded Product: 3,3,3-Trifluoropropan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Bernhardt, Annika published the artcileThe Strong β-CF₃ Shielding Effect in Hexafluoroisopropanol and 100 Other Organic Solvents Revisited with ¹⁷O NMR Spectroscopy, Related Products of alcohols-buliding-blocks, the publication is ChemCatChem (2018), 10(7), 1547-1551, database is CAplus and MEDLINE.

An ¹⁷O NMR spectroscopy survey of more than 100 ubiquitous organic solvents and compounds, including some typical oxofluorinated solvents such as hexafluoroisopropanol, trifluoroethanol, trifluoroacetic acid, and others, is presented with D₂O as a reference A strong alternating α,β-CF₃-substituent chem. shift effect was thus observed This alternating deshielding-shielding effect is suspected to have a role in the exceptional properties of these oxofluorinated solvents, notably in oxidative cross-coupling reactions.

ChemCatChem published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yadav, B. P. published the artcileSynthesis of some novel pyrimidine derivatives and compared to available antimicrobial (MTCC inhibitors) drugs, Recommanded Product: 3,3,3-Trifluoropropan-1-ol, the publication is IOSR Journal of Pharmacy (2021), 11(9-1), 23-28, database is CAplus.

A new series of pyrimidine derivatives I (R¹ = trifluoromethyl, Cl; R² = Me, Et, i-Pr) have been synthesized by reacting substituted pyrimidine carboxylic acids II with 3-methoxyaniline, de-methylation using BBr₃ to form hydroxy derivatives, which were then alkylated with resp. alkyl halides R²I to synthesize substituted pyrimidine derivatives I. The synthesized compounds I were screened for their in vitro growth inhibiting activity against different strains.

IOSR Journal of Pharmacy published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C15H10O2, Recommanded Product: 3,3,3-Trifluoropropan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Barker, Graeme published the artcileChirality Transfer in Gold(I)-Catalysed Direct Allylic Etherifications of Unactivated Alcohols: Experimental and Computational Study, Safety of 3,3,3-Trifluoropropan-1-ol, the publication is Chemistry – A European Journal (2015), 21(39), 13748-13757, database is CAplus and MEDLINE.

Gold(I)-catalyzed direct allylic etherifications have been successfully carried out with chirality transfer to yield enantioenriched, γ-substituted secondary allylic ethers. Our investigations include a full substrate-scope screen to ascertain substituent effects on the regioselectivity, stereoselectivity and efficiency of chirality transfer, as well as control experiments to elucidate the mechanistic subtleties of the chirality-transfer process. Crucially, addition of mol. sieves was found to be necessary to ensure efficient and general chirality transfer. Computational studies suggest that the efficiency of chirality transfer is linked to the aggregation of the alc. nucleophile around the reactive π-bound Au-allylic ether complex. With a single alc. nucleophile, a high degree of chirality transfer is predicted. However, if three alcs. are present, alternative proton transfer chain mechanisms that erode the efficiency of chirality transfer become competitive.

Chemistry – A European Journal published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, Safety of 3,3,3-Trifluoropropan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Antinolo, M. published the artcilePhotochemistry of CF₃(CH₂)₂CHO in air: UV absorption cross sections between 230 and 340 nm and photolysis quantum yields at 308 nm, Recommanded Product: 3,3,3-Trifluoropropan-1-ol, the publication is Journal of Photochemistry and Photobiology, A: Chemistry (2012), 231(1), 33-40, database is CAplus.

This work constitutes the first study on the photochem. degradation process of CF₃(CH₂)₂CHO. First, the wavelength and temperature dependence of the UV absorption cross sections, σ_λ, was determined The n → π^* electronic transition band of C=O chromophore was characterized between 230 and 340 nm in the 269-323 K range. A hyperchromic effect was observed in the structured part of the band when the temperature decreases. The pulsed laser photolysis of a stationary mixture of CF₃(CH₂)₂CHO/cyclohexane (OH-scavenger)/air or N₂ was carried out at 308 nm. Online Fourier transform IR (FTIR) spectroscopy was employed to monitor the decay of CF₃(CH₂)₂CHO and to obtain the photolysis quantum yield as a function of total pressure (20.5-760 Torr). A slight curvature in the Stern-Volmer plot was observed at pressures lower than 75 Torr. At high pressures, the pressure dependence of can be described by a Stern-Volmer relationship. Photodissociation of CF₃(CH₂)₂CHO at 308 nm can produce HCO and CF₃(CH₂)₂ radicals , CF₃CH₂CH₃ and CO and CF₃(CH₂)₂CO radicals and H atoms. HCO radicals are rapidly converted into CO in the presence of O₂. Formation of CF₃CH₂CHO and CF₃CH₂CH₂OH evidences the importance of secondary chem. involving CF₃(CH₂)₂ radicals formed in channel . Further photodegradation of CF₃CH₂CHO yields mainly CF₃CHO. Small quantities of HC(O)OH were also detected. CF₃(CH₂)₂C(O)OH was only observed in the absence of OH-scavenger, implying that formation of CF₃(CH₂)₂CO radicals in channel is not an important photolysis pathway. Consequently, photodissociation of CF₃(CH₂)₂CHO in the actinic region is a source of shorter fluorinated oxygenated compounds, but it is not expected to be a source of fluorinated acids.

Journal of Photochemistry and Photobiology, A: Chemistry published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, Recommanded Product: 3,3,3-Trifluoropropan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Antinolo, Maria published the artcileAtmospheric removal of a series of fluoroalcohols and fluoroaldehydes: photochemistry initiated by OH radicals and sunlight, Category: alcohols-buliding-blocks, the publication is Trends in Photochemistry & Photobiology (2013), 89-103, database is CAplus.

A review. Hydrofluorocarbons (HFCs) are one of the alternatives to ozone-depleting chlorofluorocarbons (CFCs) in refrigeration, air conditioning and foam blowing. But their high global warming potentials (GWPs) have given rise to the concern that increased use and direct emissions of HFCs could have a significant impact on climate change. Some other CFC alternatives such as fluorinated alcs. (FAs) have been proposed in many industrial applications. The tropospheric photooxidation of FAs yields fluorinated aldehydes as secondary pollutants. To evaluate the tropospheric persistence of these species it is necessary to determine the rate coefficients of the main removal pathways in the gas-phase, namely UV photolysis and reaction with hydroxyl (OH) (J and k_OH, resp.). The tropospheric lifetimes (*au) of a species can be calculated from J and k_OH. In this article, the gas-phase kinetics of OH radicals with CF₃CH₂CH₂OH, CF₃(CH₂)₂CH₂OH, CF₃CF₂CH₂OH, CHF₂CF₂CH₂OH, CF₃CH₂CHO, CF₃(CH₂)₂CHO and CF₃CF₂CHO recently reported by our research group, as a function of temperature (263-359 K) and pressure (40-215 Torr of He), is reviewed. The determination of k_OH as a function of temperature was performed by Pulsed Laser Photolysis – Laser Induced Fluorescence (PLP – LIF). Furthermore, a photochem. study of the fluorinated compounds at 308 nm (in the actinic region) is also reviewed here, including the determination of the UV absorption cross sections (σ_λ) between 200 and 370 nm and photodissociation quantum yields by PLP at 308 nm coupled to Fourier transform IR (FTIR) spectroscopy (Φ_λ = 308nm). The formation of the photodegradation products initiated by absorption of UV radiation at 308 nm in a simulated clean atm. is also reviewed. It can be concluded that hydrofluorinated alcs. (HFAs) are suitable for replacing HFCs, since they are short-lived compounds that do not contribute to the Earth’s global warming. The degradation of these fluorocompounds is not expected to significantly contribute to air pollution in free-NO_x atmospheres.

Trends in Photochemistry & Photobiology published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Antinolo, Maria published the artcileTemperature Effects on the Removal of Potential HFC Replacements, CF₃CH₂CH₂OH and CF₃(CH₂)₂CH₂OH, Initiated by OH Radicals, Category: alcohols-buliding-blocks, the publication is Environmental Science & Technology (2011), 45(10), 4323-4330, database is CAplus and MEDLINE.

Gas phase kinetic coefficients of OH^– with 2 primary fluorinated alcs., CF₃CH₂CH₂OH (k₁) and CF₃(CH₂)₂CH₂OH (k₂), potential hydrofluorocarbon (HFC) replacements, are reported as a function of temperature (263-358° K) for the first time. K₁ and k₂ (together referred to as k_i) were measured under pseudo-first-order conditions with respect to the initial OH^– concentration using the pulsed laser photolysis/laser-induced fluorescence technique. The observed k_i temperature dependence (in cm³/mol.-s) is described by the following Arrhenius expressions: k₁(T) = (2.82 ± 1.28) × 10^-12 exp{-(302 ± 139)/T} cm³/mol.-s and k₂(T) = (1.20 ± 0.73) × 10^-11 exp{-(425 ± 188)/T} cm³/mol.-s. Arrhenius parameter uncertainties are at a 95% confidence level (±2σ). K_i(T) uncertainties include statistical and systematic errors. Activation energies were (2.5 ± 1.2) kJ/mol and (3.6 ± 1.6) kJ/mol for the OH^–-reaction with CF₃CH₂CH₂OH and CF₃(CH₂)₂CH₂OH, resp. Global lifetime (τ) at 275° K for CF₃CH₂CH₂OH and CF₃(CH₂)₂CH₂OH due to the OH^–-reaction was estimated to be approx. 2 wk and 5 days, resp. Reported Arrhenius parameters can be used in 3-dimensional models which account for geog. region and season of emissions to estimate a matrix of instantaneous lifetimes. As a consequence of the substitution of the -CH₃ group by a -CH₂OH group in HFC, e.g., CF₃CH₂CH₃ and CF₃(CH₂)₂CH₃, the tropospheric lifetime with respect to the OH^– reaction is significantly shorter, and, since their radiative forcing is similar, global warming potentials for CF₃CH₂CH₂OH and CF₃(CH₂)₂CH₂OH are negligible. Thus, CF₃CH₂CH₂OH and CF₃(CH₂)₂CH₂OH seem to be suitable alternatives for HFC.

Environmental Science & Technology published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ramachandran, P. Veeraraghavan published the artcileCritical Role of Catalysts and Boranes for Controlling the Regioselectivity in the Rhodium-Catalyzed Hydroboration of Fluoroolefins, Product Details of C3H5F3O, the publication is Organic Letters (1999), 1(9), 1399-1402, database is CAplus.

Catalytic hydroboration of perfluoroalkylethylenes (R_FCH:CH₂) with cationic and neutral rhodium complexes allows for selective access to either regioisomeric alc. after hydroboration with catechol- and pinacolboranes, followed by oxidation with alk. hydrogen peroxide.

Organic Letters published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, Product Details of C3H5F3O.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Otsuka, Takashi published the artcilePractical Selective Hydrogenation of α-Fluorinated Esters with Bifunctional Pincer-Type Ruthenium(II) Catalysts Leading to Fluorinated Alcohols or Fluoral Hemiacetals, HPLC of Formula: 2240-88-2, the publication is Journal of the American Chemical Society (2013), 135(26), 9600-9603, database is CAplus and MEDLINE.

Selective hydrogenation of fluorinated esters with pincer-type bifunctional catalysts RuHCl(CO)(dpa) 1a, trans-RuH₂(CO)(dpa) 1b, and trans-RuCl₂(CO)(dpa) 1c (I; X = H, Cl; H, H; Cl, Cl, resp.) under mild conditions proceeds rapidly to give the corresponding fluorinated alcs. or hemiacetals in good to excellent yields. Under the optimized conditions, the hydrogenation of chiral (R)-2-fluoropropionate proceeds smoothly to give the corresponding chiral alc. without any serious decrease of the ee value.

Journal of the American Chemical Society published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, HPLC of Formula: 2240-88-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Dimitrova, Maria published the artcileReactivity descriptors for the hydrogen bonding ability of aliphatic alcohols, HPLC of Formula: 2240-88-2, the publication is Journal of Molecular Structure (2003), 657(1-3), 317-324, database is CAplus.

A series of 18 aliphatic alcs. and their hydrogen-bonded complexes with ammonia are studied by applying d. functional theory computations at the B3LYP/631G(d,p) level. Theor. determined electronic parameters-partial at. charges and electrostatic potential at nuclei (EPN)-are employed to characterize the reactivity of the monomer alcs. The variations of binding energy are also interpreted in terms of the well-known exptl. solvatochromic parameters, α. It is shown that both the exptl. α constants and EPN values characterize quant. the reactivity of the studied mols. toward the complexation process. A linear link between α constants and EPN values was also found.

Journal of Molecular Structure published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, HPLC of Formula: 2240-88-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts