Category: 20880-92-6

Mou, Lin-Yun published the artcilePhytochemical and chemotaxonomic investigation from the roots of Anemone vitifolia Buch.-Ham. (Ranunculaceae), HPLC of Formula: 20880-92-6, the publication is Biochemical Systematics and Ecology (2021), 104306, database is CAplus.

Phytochem. investigation from the roots of Anemone vitifolia Buch.-Ham. led to the isolation of eight compounds, including one triterpenoid saponin, two sugars, one coumarin, one amide, one saturated alkane, one olefin and one fatty acid. The structures of these metabolites were elucidated by spectroscopic data and comparisons with the data available in the literature. Among them, compound 7 ((6Z,9Z,12Z)-6,9,12-Eicosatriene) was isolated for the first time as a natural product. Furthermore, compounds 2 (D-(+)-raffinose), 3 (mixture of β-D-fructopyranose and β-D-fructofuranose) and 5 (bonaroside) were obtained from the Ranunculaceae family for the first time. Compounds 4 (siderin) and 6 (n-hexadecane) were isolated from A. vitifolia for the first time. The chemotaxonomic significance of the isolated compounds was discussed.

Biochemical Systematics and Ecology published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, HPLC of Formula: 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Weber, Christine published the artcileCarbohydrate-Based Initiators for the Cationic Ring-Opening Polymerization of 2-Ethyl-2-Oxazoline, Category: alcohols-buliding-blocks, the publication is Methods in Molecular Biology (New York, NY, United States) (2016), 49-59, database is CAplus and MEDLINE.

The advancement in the field of living and controlled polymerization techniques provides the opportunity for careful bottom-up design of polymers for biomedical applications according to their specific needs. This contribution describes the detailed methodol. to functionalize poly(2-ethyl-2-oxazoline), a polymer with properties very similar to polyethylene glycol, in a stereo-selective manner with a range of carbohydrates that can serve as biol. targeting units. The obtained building blocks can subsequently be applied for the synthesis of more complex polymeric architectures.

Methods in Molecular Biology (New York, NY, United States) published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C5H12BrO3P, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yildirim, Ayhan published the artcileD-Fructose-Derived Acetonide as a Green Neutral Organocatalyst for Proficient One-Pot and Three-Component Preparation of 1,3-Benzoxazine Monomers, Product Details of C12H20O6, the publication is ChemistrySelect (2020), 5(23), 6971-6977, database is CAplus.

A series of 1,3-benzoxazine monomers were successfully synthesized by simple one-pot and three-component condensation of phenol, paraformaldehyde and varying types of primary aliphatic and aromatic amines in a molar ratio of 1 : 2 : 1 and in the presence of non-acidic 2,3;4,5-di-O-isopropylidene-β-D-fructopyranose as an effective green carbohydrate based organocatalyst obtained from renewable feedstock. This multicomponent method provided a convenient fast approach for the construction of valuable 1,3-benzoxazine monomers (8 examples) with moderate to excellent yields. The chem. structures of the synthesized benzoxazines were confirmed by FTIR, ¹H NMR, ¹³C NMR spectra and elemental anal.

ChemistrySelect published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C23H20BN, Product Details of C12H20O6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Pinto, Eduardo Costa published the artcileDevelopment and validation of a stability-indicating HPLC method for topiramate using a mixed-mode column and charged aerosol detector, Computed Properties of 20880-92-6, the publication is Journal of Separation Science (2018), 41(8), 1716-1725, database is CAplus and MEDLINE.

The anal. of topiramate in the presence of its main degradation products is challenging due to the absence of chromophore moieties and their wide range of polarity. Mixed-mode chromatog. has been used in such cases because it combines two or more modes of separation Charged aerosol detector is also an alternative since its detection is independent of optical properties and analyte ionization. This study is aimed to develop and validate two new stability-indicating methods by high-performance liquid chromatog. for the main degradation products of topiramate using mixed-mode chromatog. and a charged aerosol detector. Method 1 employed an Acclaim Trinity P1 column (3.0 mm × 150 mm, 2.7 μm) with a mobile phase comprising of 80% ammonium acetate buffer (20 mM, pH 4.0) and 20% methanol at a flow rate of 0.5 mL/min at 35°C. Method 2 utilized a C18 Acclaim 120 column (4.6 mm × 250 mm; 5 μm) with ACN/water (50:50) at a flow rate of 0.6 mL/min at 50°C. Validation of the two methods demonstrated excellent performance with respect to linearity, precision, accuracy, and selectivity. The limits of detection for topiramate, fructose, sulfate, sulfamate, and compound A were 2.97, 12.08, 4.02, 13.91, and 3.94 μg/mL, resp.

Journal of Separation Science published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, Computed Properties of 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liu, Jiandong published the artcileNickel-catalyzed, regio- and enantioselective benzylic alkenylation of olefins with alkenyl bromide, SDS of cas: 20880-92-6, the publication is Angewandte Chemie, International Edition (2021), 60(8), 4060-4064, database is CAplus and MEDLINE.

A NiH-catalyzed migratory hydroalkenylation reaction of olefins with alkenyl bromides has been developed, affording benzylic alkenylation products with high yields and excellent chemoselectivity. The mild conditions of the reaction preclude olefinic products from undergoing further isomerization or subsequent alkenylation. Catalytic enantioselective hydroalkenylation of styrenes was achieved by using a chiral bisoxazoline ligand.

Angewandte Chemie, International Edition published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, SDS of cas: 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Jia-Xin published the artcilePhotoredox-Catalyzed Allylic Defluorinative Alkoxycarbonylation of Trifluoromethyl Alkenes through Intermolecular Alkoxycarbonyl Radical Addition, Recommanded Product: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, the publication is Organic Letters (2022), 24(7), 1471-1475, database is CAplus and MEDLINE.

Herein, a photoredox-catalyzed allylic defluorinative alkoxycarbonylation of trifluoromethyl alkenes ArC(CF₃):CH₂ (Ar = 4-BrC₆H₄, naphthalen-2-yl, 6-methoxypyridin-3-yl, etc.) enabled by intermol. alkoxycarbonyl radical addition is disclosed. A wide variety of alc. oxalate derivatives ROC(O)CO₂H (R = Me, t-Bu, cyclopentyl, L-menthyl, N-Boc-piperidin-4-yl, etc.) was amenable, affording various β-gem-difluoroalkene esters ArC(:CF₂)CH₂COOR with excellent functional group tolerance. Notably, the potential synthetic value of this method is highlighted by successful late-stage modification for bioactive mols.

Organic Letters published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C18H34N4O5S, Recommanded Product: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Youcan published the artcilePalladium-Catalyzed Carbonylative Four-Component Synthesis of β-Perfluoroalkyl Amides, HPLC of Formula: 20880-92-6, the publication is Chemistry – A European Journal (2021), 27(70), 17682-17687, database is CAplus and MEDLINE.

Transition-metal-catalyzed multicomponent carbonylation is one of the most efficient strategies to construct carbonyl-containing compounds Herein, a palladium-catalyzed four-component perfluoroalkylation/aminocarbonylation of unactivated alkenes with perfluoroalkyl halides, and amines was developed. A wide range of substrates, including anilines, alkylamines, sulfonamides, and hydrazines are all suitable reaction partners for this catalyst system, resulting in various β-perfluoroalkyl amides with good functional-group tolerance and excellent chemoselectivity. Furthermore, not only alkyl olefins, but also aliphatic alkynes, and even alkyl allenes can all be employed. Notably, several medical and bioactive related mols. are compatible here as well.

Chemistry – A European Journal published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C19H14O2, HPLC of Formula: 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Horakova, Eva published the artcileSynthesis and in vitro evaluation of novel N-cycloalkylcarbamates as potential cholinesterase inhibitors, Application of ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, the publication is Monatshefte fuer Chemie (2017), 148(12), 2143-2153, database is CAplus.

Abstract: This present paper describes the preparation and characterization of a series of O-substituted N-cycloalkylcarbamate derivatives These compounds were tested as inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). All studied carbamates exhibited moderate inhibitory activity of both cholinesterases with values of IC₅₀ in the range of 36.1-78.6 μM for AChE and 9.8-215.4 μM for BChE, resp. These values are comparable with those values of inhibition obtained with the established drug rivastigmine. The cytotoxicity of all carbamates was evaluated using standard in vitro test with Jurkat cells. Many of the studied carbamates can be considered as promising compounds for potential medicinal applications with regard to their inhibitory activity as well as negligible cytotoxicity. Graphical abstract: [Figure not available: see fulltext.].

Monatshefte fuer Chemie published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, Application of ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Huang, Yongliang published the artcileConvenient and flexible syntheses of gem-dimethyl carboxylic triggers via mono-selective β-C(sp³)-H arylation of pivalic acid with ortho-substituted aryl iodides, Computed Properties of 20880-92-6, the publication is Organic Chemistry Frontiers (2022), 9(12), 3293-3300, database is CAplus.

This work presents a palladium(II)-catalyzed mono-selective C(sp³)-H arylation of pivalic acid for rapid construction of an important library of 3-aryl-2,2-dimethylpropanoic acids, especially ortho-substituted-aryl compounds The strategy greatly streamlines access to a series of trimethyl-lock-type triggers – arylated gem-di-Me carboxylic acids bearing ortho-activatable substituents, which was used as a self-immolative spacer for selective chem. release initiated under specific conditions. Flexible transformation and derivatization of these activatable carboxylic triggers were also showcased.

Organic Chemistry Frontiers published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, Computed Properties of 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yan, KaKing published the artcileChiral Crystalline Sponges for the Absolute Structure Determination of Chiral Guests, Recommanded Product: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, the publication is Journal of the American Chemical Society (2017), 139(33), 11341-11344, database is CAplus and MEDLINE.

Chiral crystalline sponges [(ZnI₂)₃(tpt)₂]_n·xG^* (1) where tpt = 2,4,6-tris(4-pyridyl)-1,3,5-triazine; G^* = (S,S) or (R,R)-4,5-dimethyl-2-(triphenylen-2-yl)-1,3-dioxolane, with preinstalled chiral references were synthesized. On the basis of the known configurations of the chiral references, the absolute structures of guest compounds absorbed in the pores of the crystalline sponges can be reliably determined without crystallization or chem. modification.

Journal of the American Chemical Society published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C21H37BO, Recommanded Product: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts