1777-82-8 Archives - Page 4 of 7 - Alcohols-buliding-blocks

Karthik, Shanmugam et al. published their research in Journal of Organic Chemistry in 2019 | CAS: 1777-82-8

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Quality Control of (2,4-Dichlorophenyl)methanol

Base-Promoted Amidation and Esterification of Imidazolium Salts via Acyl C-C bond Cleavage: Access to Aromatic Amides and Esters was written by Karthik, Shanmugam;Muthuvel, Karthick;Gandhi, Thirumanavelan. And the article was included in Journal of Organic Chemistry in 2019.Quality Control of (2,4-Dichlorophenyl)methanol This article mentions the following:

Imidazolium salts have been effectively employed as suitable acyl transfer agents in amidation and esterification in organic synthesis. The weak acyl C(O)-C imidazolium bond was exploited to generate acyl electrophiles, which further react with amines and alcs. to afford amides and esters. The broad substrate scope of anilines and benzylic amines and base-promoted conditions are the benefits of this route. Interestingly, phenol, benzylic alcs., and a biol. active alc. can also be subjected to esterification under the optimized conditions. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Quality Control of (2,4-Dichlorophenyl)methanol).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yadav, Anamika et al. published their research in European Journal of Organic Chemistry in 2020 | CAS: 1777-82-8

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Quality Control of (2,4-Dichlorophenyl)methanol

Silver/Palladium Relay Catalyzed Cross-Coupling of N’-Acetyl-8-quinolinesulfonylhydrazide with Alcohols: An Easy Access to 8-Quinolinesulfinate Esters was written by Yadav, Anamika;Ambule, Mayur D.;Kant, Ruchir;Srivastava, Ajay K.. And the article was included in European Journal of Organic Chemistry in 2020.Quality Control of (2,4-Dichlorophenyl)methanol This article mentions the following:

An efficient strategy for the synthesis of unexplored 8-quinolinesulfinate esters has been reported. The method involves in situ generation of quinoline sulfinate from N’-acetylquinoline-8-sulfonohydrazide via silver mediated cleavage followed by palladium-catalyzed cross-coupling with 1° and 2° alcs. to yield sulfinate esters. A variety of substituted alcs. were successfully employed in the reaction. Control experiments performed to understand the mechanism, revealed that the transformation follows a radical pathway and the alc. oxygen get incorporated in the resulting sulfinate esters. Two of the chirally pure alcs. were also used in the transformation to study the diastereoselectivity in the reaction. In order to demonstrate the synthetic utility, a representative allyl quinoline-8-sulfinate (I) was successfully converted into the 8-(allylsulfonyl)quinoline (II) via palladium(II) acetate mediated isomerization. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Quality Control of (2,4-Dichlorophenyl)methanol).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Peng et al. published their research in RSC Advances in 2018 | CAS: 1777-82-8

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application of 1777-82-8

Transfer hydrogenation of aldehydes catalyzed by silyl hydrido iron complexes bearing a [PSiP] pincer ligand was written by Zhang, Peng;Li, Xiaoyan;Qi, Xinghao;Sun, Hongjian;Fuhr, Olaf;Fenske, Dieter. And the article was included in RSC Advances in 2018.Application of 1777-82-8 This article mentions the following:

The synthesis and characterization of a series of silyl hydrido iron complexes bearing a pincer-type [PSiP] ligand (2-R₂PC₆H₄)₂SiH₂ (R = Ph (1) and ⁱPr (5)) or (2-Ph₂PC₆H₄)₂SiMeH (2) were reported. Preligand 1 reacted with Fe(PMe₃)₄ to afford complex ((2-Ph₂PC₆H₄)SiH)Fe(H)(PMe₃)₂ (3) in toluene, which was structurally characterized by x-ray diffraction. ((2-ⁱPr₂PC₆H₄)SiH)Fe(H)(PMe₃) (6) could be obtained from the reaction of preligand 5 with Fe(PMe₃)₄ in toluene. Furthermore, complex ((2-ⁱPr₂PC₆H₄)Si(OMe))Fe(H)(PMe₃) (7) was isolated by the reaction of complex 6 with 2 equiv MeOH in THF. The mol. structure of complex 7 was also determined by single-crystal x-ray anal. Complexes 3, 4, 6 and 7 showed good to excellent catalytic activity for transfer hydrogenation of aldehydes under mild conditions, using 2-propanol as both solvent and hydrogen donor. α,β-Unsaturated aldehydes could be selectively reduced to corresponding α,β-unsaturated alcs. The catalytic activity of penta-coordinate complex 6 or 7 is stronger than that of hexa-coordinate complex 3 or 4. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Application of 1777-82-8).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application of 1777-82-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Adil, Syed Farooq et al. published their research in Catalysts in 2019 | CAS: 1777-82-8

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.HPLC of Formula: 1777-82-8

A facile synthesis of ZrOx-MnCO₃/graphene oxide (GRO) nanocomposites for the oxidation of alcohols using molecular oxygen under base free conditions was written by Adil, Syed Farooq;Assal, Mohamed E.;Shaik, Mohammed Rafi;Kuniyil, Mufsir;AlOtaibi, Nawaf M.;Khan, Mujeeb;Sharif, Muhammad;Alam, M. Mujah;Al-Warthan, Abdulrahman;Mohammed, Jabair Ali;Sdiqui, Mohammed Rafiq H.;Tahir, Muhammad Nawaz. And the article was included in Catalysts in 2019.HPLC of Formula: 1777-82-8 This article mentions the following:

Graphene and its nanocomposites are showing excellent potential in improving the catalytic performances of different materials. However, the synthetic protocol and its form, such as graphene oxide (GRO) or highly reduced graphene oxide (HRG), influence the catalytic efficiencies. Here, we present, a facile synthesis of graphene oxide (GRO) and ZrOx-MnCO₃-based nanocomposites [(1%)ZrOx-MnCO₃/(x%)GRO] and their outcome as an oxidation catalyst for alc. oxidation under mild conditions using O2 as a clean oxidant. The ZrOx-MnCO₃/GRO catalyst prepared by incorporating GRO to pre-calcined ZrOx-MnCO₃ using ball milling showed remarkable enhancement in the catalytic activities as compared to pristine ZrOx-MnCO₃, ZrOx-MnCO₃ supported on HRG or ZrOx-MnCO₃/GRO prepared by in-situ growth of ZrOx-MnCO₃ onto GRO followed by calcination. The catalyst with composition (1%)ZrOx-MnCO₃/(1%)GRO exhibited superior specific activity (57.1 mmol/g·h) with complete conversion and >99% selectivity of the product within a short period of time (7 min) and at a relatively lower temperature (100°C). The catalyst could be recycled at least five times with a negligible decrease in efficiency and selectivity. The catalytic study was extended to different aromatic as well as aliphatic alcs. under optimized conditions, which confirmed the efficiency and selectivity of the catalyst. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8HPLC of Formula: 1777-82-8).

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

09/24/21 News A new synthetic route of 1777-82-8

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1777-82-8, (2,4-Dichlorophenyl)methanol, and friends who are interested can also refer to it.

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.1777-82-8, name is (2,4-Dichlorophenyl)methanol, molecular formula is C7H6Cl2O, molecular weight is 177.03, as common compound, the synthetic route is as follows.Formula: C7H6Cl2O

General procedure: A mixture of alcohol or phenol (1 mmol), DHP (1.2-1.4 mmol), and MNPs-PSA (5 mg, 0.95 mol%) was stirred at room temperature in dry CH2Cl2 (2 mL), and the progress of the reaction was monitored by TLC. After completion of the reaction, catalyst was separated by an external magnet and washed with CH2Cl2. Then, the pure product was isolated by passing of the reaction mixture through a short column using n-hexane and ethyl acetate (9:1) as eluent.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1777-82-8, (2,4-Dichlorophenyl)methanol, and friends who are interested can also refer to it.

Reference:
Article; Rostami, Amin; Tahmasbi, Bahman; Abedi, Fatemeh; Research on Chemical Intermediates; vol. 42; 4; (2016); p. 3689 – 3701;,
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Extracurricular laboratory: Synthetic route of (2,4-Dichlorophenyl)methanol

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1777-82-8, its application will become more common.

Synthetic Route of 1777-82-8, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 1777-82-8 as follows.

The reactants used were 2,4-dichlorobenzyl alcohol (i.e., R1 in the formula (I) was ortho, with two Cl) 1.0 mmol(177.0 mg), the experimental method and procedure were the same as in Example 1, ammonia water (1.8 mol / L) 5.0 mL, and the amount of catalyst cuprous bromide was5 mol% (7.2 mg), TEMPO was used in an amount of 5 mol% (7.8 mg), the reaction temperature was 80 C, the reaction time was 24 h, and the crude productPurification by column chromatography (petroleum ether: ethyl acetate = 10: 1) gave the pure title product, yielded 166.8 mg yield 97%.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1777-82-8, its application will become more common.

Reference:
Patent; Zhejiang University of Technology; Zhang Guofu; Zhao Yiyong; Zhang Guihua; Ding Chengrong; Yu Yidong; Lv Jinghui; (10 pag.)CN106866326; (2017); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Extracurricular laboratory: Synthetic route of (2,4-Dichlorophenyl)methanol

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1777-82-8, its application will become more common.

Application of 1777-82-8, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 1777-82-8 as follows.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1777-82-8, its application will become more common.

A new synthetic route of (2,4-Dichlorophenyl)methanol

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 1777-82-8, (2,4-Dichlorophenyl)methanol.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1777-82-8, name is (2,4-Dichlorophenyl)methanol. This compound has unique chemical properties. The synthetic route is as follows. COA of Formula: C7H6Cl2O

General procedure: A mixture of 6 mmol of the alcohol or the amine and5 mmol o-phenylenediamine, o-aminophenol or o-aminothiophenol,10 mol % Fe2(SO4)3, 10 mol % TEMPO wasprepared in a 10 ml three-necked flask, and then stirred inopen air at 110 C for several hours, The reaction progresswas monitored by TLC. When the final reaction mixturecooled to room temperature, the crude products was directlypurified by column chromatography on silica gel using hexane/ethyl acetate (7:3) as eluent to afford the pure product.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 1777-82-8, (2,4-Dichlorophenyl)methanol.

Reference:
Article; Yu, Jiatao; Shen, Mengnan; Lu, Ming; Journal of the Iranian Chemical Society; vol. 12; 5; (2015); p. 771 – 778;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A new synthetic route of 1777-82-8

The synthetic route of 1777-82-8 has been constantly updated, and we look forward to future research findings.

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1777-82-8, name is (2,4-Dichlorophenyl)methanol, the common compound, a new synthetic route is introduced below. HPLC of Formula: C7H6Cl2O

General procedure: In a general process, the photocatalytic activity of nanostructureswas investigated by oxidation of aromatic alcohol. In typically,0.1 mmol of alcohol was added to 1.5 ml of solvent in Pyrex glass celland stirred for 5 min. Then, 10 mg of photocatalyst was dispersed insolution and magnetically stirred in the dark for 15 min to reach anequilibrium between adsorption-desorption. Photocatalytic reactionswere performed by irradiation with an LED lamp (5 W). To control thetemperature during the oxidation reaction, the water circulation wasapplied to cooling of the reaction mixture. During the photocatalyticprocess, the reactor was exposed to air to ensure that enough oxygen isprovided for the reaction. The progress of the reaction was monitoredusing the TLC by periodic sampling. After completion of the reaction,the catalyst was separated from the suspension by centrifuging(3500 rpm) and washed with solvent to separate all of the residualmaterials.

The synthetic route of 1777-82-8 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Safaei, Elham; Mohebbi, Sajjad; Journal of Photochemistry and Photobiology A: Chemistry; vol. 371; (2019); p. 173 – 181;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Share a compound : (2,4-Dichlorophenyl)methanol

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1777-82-8, (2,4-Dichlorophenyl)methanol, and friends who are interested can also refer to it.

General procedure: In a 50ml Pyrex round-bottom flask, a mixture of alcohol (1mmol), TBATB (10-20mg, 0.02-0.04mmol) in 10ml of CH3CN was exposed to blue or violet light LED irradiation at room temperature under an air atmosphere with stirring. The progress of the photocatalytic oxidation reaction was monitored by TLC on silica gel plates. The reaction mixture externally irradiated until the alcohol was completely consumed.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1777-82-8, (2,4-Dichlorophenyl)methanol, and friends who are interested can also refer to it.

Reference:
Article; Mardani, Atefeh; Heshami, Marouf; Shariati, Yadollah; Kazemi, Foad; Abdollahi Kakroudi, Mazaher; Kaboudin, Babak; Journal of Photochemistry and Photobiology A: Chemistry; vol. 389; (2020);,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts