Category: 1777-82-8

Preparation, characterization and heterogeneous catalytic applications of GO/Fe₃O₄/HPW nanocomposite in chemoselective and green oxidation of alcohols with aqueous H₂O₂ was written by Darvishi, Kamran;Amani, Kamal;Rezaei, Manuchehr. And the article was included in Applied Organometallic Chemistry in 2018.HPLC of Formula: 1777-82-8 This article mentions the following:

Graphene oxide-Fe₃O₄-NH₃⁺H₂PW₁₂O₄₀^– magnetic nanocomposite (GO/Fe₃O₄/HPW) was prepared by linking amino-functionalized Fe₃O₄ nanoparticles (Fe₃O₄-NH₂) on the graphene oxide (GO), and then grafting 12-tungstophosphoric acid (H₃PW₁₂O₄₀) on the graphene oxide-magnetite hybrid (GO-Fe₃O₄-NH₂). The obtained GO/Fe₃O₄/HPW nanocomposite was well characterized with different techniques such as FT-IR, TEM, SEM, XRD, EDX, TGA-DTA, AGFM, ICP and BET measurements. The used techniques showed that the graphene oxide layers were well prepared and the various stages of preparation of the GO/Fe₃O₄/HPW nanocomposites successfully completed. This new nanocomposite displayed excellent performance as a heterogeneous catalyst in the oxidation of alcs. with H₂O₂. The as-prepared GO/Fe₃O₄/HPW catalyst was more stable and recyclable at least five times without significantly reducing its catalytic activity. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8HPLC of Formula: 1777-82-8).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.HPLC of Formula: 1777-82-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

伪-Oxygenation of Benzylic Ethers to Esters Using MnO_x-N@C Catalyst was written by Liu, Jing;Wan, Cong;Zheng, Aili;Wang, Lianyue;Yin, Kaiyue;Liu, Dandan;Wang, Shengde;Ren, Lanhui;Gao, Shuang. And the article was included in Youji Huaxue in 2019.Name: (2,4-Dichlorophenyl)methanol This article mentions the following:

A catalytic system for the oxidation of benzylic ethers 2-R-3-R¹-4-R²-5-R³-6-R⁴C₆CH₂OR⁵ (R = H, OH, Cl, OMe, etc.; R¹ = H, Me, OMe, CF₃; RR¹ = -CH=CH-CH=CH-; R² = H, i-Pr, Cl, Ph, etc.; R¹R² = -OCH₂O-; R³ = H; R⁴ = H, Cl; R³R⁴ = -CH=CH-CH=CH-; R⁵ = Me, Et, Bn; R⁴R⁵ = -(CH₂)₂-, -CH₂-) to esters 2-R-3-R¹-4-R²-5-R³-6-R⁴C₆C(O)OR⁵ has been developed utilizing reusable MnO_x-N@C as catalyst and tert-Bu hydroperoxide (TBHP) as benign oxidant under neat condition. The catalytic oxidation system has good functional groups tolerance and excellent chemoselectivity, and this catalytic procedure can also be scaled up. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Name: (2,4-Dichlorophenyl)methanol).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Name: (2,4-Dichlorophenyl)methanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Selectfluor-Enabled C(sp³)-H Alkoxylation of 3-Methylfuranocoumarins was written by Qin, Zengxin;Zhao, Mengfei;Zhang, Kaixin;Goto, Masuo;Lee, Kuo-Hsiung;Li, Jizhen. And the article was included in Journal of Organic Chemistry in 2021.COA of Formula: C7H6Cl2O This article mentions the following:

A facile and metal-free method for the direct C(sp³)-H bond alkoxylation of 3-methylfuranocoumarins I (R = H, Me, NO₂; R¹ = H; R² = H; R¹R² = -CH=CH-CH=CH-; R³ = H, Me) and 4,17-dimethyl-11,15-dioxacyclopenta[a]phenanthren-12-one with alcs. R⁴OH (R⁴ = iso-Pr, cyclopentyl, 3-(2-bromophenyl)propyl, etc.) has been disclosed. Selectfluor enabled the (hetero)benzylic C-H etherification by tuning the reaction temperature and solvent. Various alcs. were compatible in this transformation with suitable yields. The mechanistic studies revealed that the reaction might undergo the double addition process of alcs., as well as the departure of a fluoride anion and the formation of an oxonium ion. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8COA of Formula: C7H6Cl2O).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. The oxygen atom of the strongly polarized O鈥旽 bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.COA of Formula: C7H6Cl2O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Novel oxovanadium and dioxomolybdenum complexes of tridentate ONO-donor Schiff base ligand: Synthesis, characterization, crystal structures, Hirshfeld surface analysis, DFT computational studies and catalytic activity for the selective oxidation of benzylic alcohols was written by Kargar, Hadi;Forootan, Pooran;Fallah-Mehrjardi, Mehdi;Behjatmanesh-Ardakani, Reza;Amiri Rudbari, Hadi;Shahzad Munawar, Khurram;Ashfaq, Muhammad;Nawaz Tahir, Muhammad. And the article was included in Inorganica Chimica Acta in 2021.Synthetic Route of C7H6Cl2O This article mentions the following:

Two new oxovanadium and dioxomolybdenum Schiff base complexes, [V^VO(L)(OCH₃)(CH₃OH)] and [Mo^VIO₂(L)(CH₂CH₃OH)], were synthesized by treating an ONO-donor type Schiff base ligand (H₂L) derived by condensation of 5-nitrosalicylaldehyde and nicotinic hydrazide with oxo and dioxo acetylacetonate salts of vanadium and molybdenum, [VO(acac)₂ and MoO₂(acac)₂], resp. The synthesized ligand and complexes were characterized by various spectroscopic techniques like FT-IR, multinuclear (¹H, ¹³C) NMR, elemental anal. and the most authentic single crystal X-ray diffraction anal. In both complexes the geometry around the central metal ions was distorted octahedral as revealed by the data collected from diffraction studies. Theor. calculation of the synthesized compounds were carried out by DFT as well as TD-DFT using B3LYP method by employing the Def2-TZVP basis set. The findings of theor. data indicated that the calculated results are in accordance with the exptl. findings. Moreover, the catalytic efficiencies of both complexes were investigated by oxidizing the benzylic alcs. in the presence of urea hydrogen peroxide (UHP) in acetonitrile. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Synthetic Route of C7H6Cl2O).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Synthetic Route of C7H6Cl2O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

CuO-Fe(III)-Zeolite-Y as efficient catalyst for oxidative alcohol-amine coupling reactions was written by Gogoi, Gautam;Baruah, Manash J.;Biswas, Subir;Hoque, Nazimul;Lee, Seonghwan;Park, Young-Bin;Saikia, Lakshi;Bania, Kusum K.. And the article was included in Molecular Catalysis in 2022.Application In Synthesis of (2,4-Dichlorophenyl)methanol This article mentions the following:

CuO nanocatalyst with layered structure was supported over Fe-exchanged zeolite-Y (CuO-Fe(III)-Y) for selective synthesis of amides by oxidative coupling of aromatic primary alcs. and amines. The CuO-Fe(III)-Y catalyst was characterized by different physicochem. and spectroscopic techniques. The amide bond formation reaction was found to occur in absence of any external base and reagents. The temperature-programmed desorption (TPD) study predicted the development of strong basic sites in the CuO-Fe(III)-Y catalyst that boosted the dehydrogenative coupling process. The activity of the material in such coupling reaction was found to be comparable to those of other costly metal catalysts under different reaction conditions. The product yield of the reaction was found to be substrate-dependent giving moderate to maximum yield of 85%. The anomalies in the reaction appeared in case of 5-nitro-2-chloro-benzylalc. that undergoes a C-N coupling product through C-Cl bond activation. The mechanism of the reaction was believed to proceed through FeIV=O species that helped in the activation of the benzylic C-H bond . In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Application In Synthesis of (2,4-Dichlorophenyl)methanol).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application In Synthesis of (2,4-Dichlorophenyl)methanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Modified WO₃ nanorod with Pt nanoparticle as retrievable materials in catalytic and photocatalytic aerobic oxidation of alcohols was written by Hosseini, Farnaz;Safaei, Elham;Mohebbi, Sajjad. And the article was included in Journal of Nanoparticle Research in 2017.Recommanded Product: 1777-82-8 This article mentions the following:

Catalytic and photocatalytic oxidation of aromatic alcs. using WO₃ nanorod and a series of Pt/WO₃ nanocomposite Pt nanoparticles was loaded on WO₃ nanorod with several mass ratios 0.1, 0.2 and 0.3 via a photoreduction process (PRP) and characterized by transmissionelectron microscopy (TEM), field emission scanning electron microscope (FE-SEM) imaging, Energy-dispersive X-rayspectroscopy (EDAZ), powder X-ray diffraction (XRD), Steady state diffuse reflectance spectroscopy (DRS), inductivelycoupledplasma (ICP) and XPS. WO₃ nanorods were obtained monodispersed with average 40nm diameter and square cross section without significant size change by the loading of platinum nanoparticles on it. Progress of oxidation reaction was monitored by GC and the yield of aerobic photocatalytic oxidation of alcs. reached up to 98% for Pt/WO₃ and 69% for WO₃ while, no oxidation was detected in the absence of light. The highest photocatalytic performance was obtained for mass ratio 0.2 with the selectivity >99%. This nanocomposite had potentials to be used as high-performance heterogeneous catalyst and photocatalyst under visible light irradiation with advantages of high activity, high selectivity and reusability. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Recommanded Product: 1777-82-8).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Recommanded Product: 1777-82-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nitrogen dioxide-catalyzed aerobic oxidation of benzyl alcohols under cocatalyst and acid-free conditions was written by Ren, Fangping;Tian, Xinzhe;Ren, Yun-Lai;Zhao, Shuang;Wang, Jianji;Zhao, Bo. And the article was included in Catalysis Communications in 2017.SDS of cas: 1777-82-8 This article mentions the following:

Nitrogen dioxide is usually considered as a mediator between dioxygen and the catalysts for the aerobic oxidation of alcs. Here, we report that nitrogen dioxide has an ability to catalyze this reaction, which not only avoids the use of the cocatalysts or the acids in traditional approaches, but also reveals a method for the present transformation with a single component catalyst. A series of primary and secondary benzyl alcs. underwent this transformation to give the targeted products in low to high yields. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8SDS of cas: 1777-82-8).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. The oxygen atom of the strongly polarized O鈥旽 bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.SDS of cas: 1777-82-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Fe(III) superoxide radicals in halloysite nanotubes for visible-light-assisted benzyl alcohol oxidation and oxidative C-C coupling of 2-naphthol was written by Baruah, Manash J.;Bora, Tonmoy J.;Dutta, Rupjyoti;Roy, Subhasish;Guha, Ankur Kanti;Bania, Kusum K.. And the article was included in Molecular Catalysis in 2021.Application of 1777-82-8 This article mentions the following:

Selective oxidation of benzyl alcs. to aldehydes and 2-naphthol to BINOL was achieved by activation of mol. oxygen (O₂) and hydrogen peroxide (H₂O₂) over an iron-oxide catalyst embedded in halloysite nanotube. ESR spectroscopy (ESR), Raman and in situ FTIR spectroscopic anal. provided direct evidence for the involvement of superoxide radical bound Fe^III species in the oxidation reaction. Both the anal. suggested the end-on binding of superoxide radical with Fe^III-center. The stability of such radical bound Fe^III-species in halloysite nanotube was analyzed through d. functional theory (DFT) calculations Results suggested that end-on (畏¹) binding was favorable by 13.5 kcal/ mol than the side-on (畏²) binding mode. The formation of such reactive species was believed to play the crucial role in bringing the high selectivity in the catalytic oxidation of benzyl alc. and oxidative C-C coupling of 2-naphthol. UV-Vis spectroscopic studies on the oxidation of benzyl alc. suggested for the initial adsorption of substrate mol. on the catalyst surface followed by its interaction with Fe^III -superoxide/hydroperoxide species generated upon photoirradiation with visible light in presence of O₂. The presence of a suitable band gap 鈭?.14 eV enabled the catalyst to catalyze the reaction under visible light irradiation Both the reactions (benzyl alc. and 2-naphthol oxidation) were tested in presence of both O₂ and H₂O₂ as oxidants at ambient temperature The influence of different parameters like rate of oxygen flow, amount of peroxide, nature of solvent, and catalyst amount on the conversion and selectivity of the reactions were studied to understand their role in the catalytic reactions. Successful oxidation of 2-naphthol with H₂O₂ as oxidant was a real success to overcome the limitations associated with this reaction using H₂O₂ as oxidant. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Application of 1777-82-8).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. The oxygen atom of the strongly polarized O鈥旽 bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Application of 1777-82-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Iron-Decorated, Guanidine Functionalized Metal-Organic Framework as a Non-heme Iron-Based Enzyme Mimic System for Catalytic Oxidation of Organic Substrates was written by Shaabani, Ahmad;Mohammadian, Reza;Farhid, Hassan;Karimi Alavijeh, Masoumeh;Amini, Mostafa M.. And the article was included in Catalysis Letters in 2019.COA of Formula: C7H6Cl2O This article mentions the following:

A novel porous functionalized metal-organic framework (MOF) as a non-heme iron-based enzyme mimic system was achieved via two-step post-synthetic modification of the MIL-101(Cr)-NH₂, and characterized by FT-IR, PXRD, TGA, SEM, EDS, CHN, BET surface area, and ICP-OES analyses. This new modified MOF (MIL-101(Cr)-guanidine-Fe) has been demonstrated to be a highly efficient, active, and reusable catalyst for oxidation of various organic substrates, including alcs., alkenes and alkyl arenes at room temperature using H₂O₂ as an oxidant. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8COA of Formula: C7H6Cl2O).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.COA of Formula: C7H6Cl2O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sequential Connection of Mutually Exclusive Catalytic Reactions by a Method Controlling the Presence of an MOF Catalyst: One-Pot Oxidation of Alcohols to Carboxylic Acids was written by Kim, Seongwoo;Lee, Ha-Eun;Suh, Jong-Min;Lim, Mi Hee;Kim, Min. And the article was included in Inorganic Chemistry in 2020.SDS of cas: 1777-82-8 This article mentions the following:

A functionalized metal-organic framework (MOF) catalyst applied to the sequential one-pot oxidation of alcs. to carboxylic acids controls the presence of a heterogeneous catalyst. The conversion of alcs. to aldehydes was acquired through aerobic oxidation using a well-known amino-oxy radical-functionalized MOF. In the same flask, a simple filtration of the radical MOF with mild heating of the solution completely altered the reaction media, providing radical scavenger-free conditions suitable for the autoxidation of the aldehydes formed in the first step to carboxylic acids. The mutually exclusive radical-catalyzed aerobic oxidation (the first step with MOF) and radical-inhibited autoxidation (the second step without MOF) are sequentially achieved in a one-pot manner. Overall, we demonstrate a powerful and efficient method for the sequential oxidation of alcs. to carboxylic acids by employing a readily functionalizable heterogeneous MOF. In addition, our MOF in-and-out method can be utilized in an environmentally friendly way for the oxidation of alcs. to carboxylic acids of industrial and economic value with broad functional group tolerance, including 2,5-furandicarboxylic acid and 1,4-benzenedicarboxylic acid, with good yield and reusability. Furthermore, MOF-TEMPO, as an antioxidative stabilizer, prevents the undesired oxidation of aldehydes, and the perfect “recoverability” of such a reactive MOF requires a re-evaluation of the advantages of MOFs from heterogeneity in catalytic and related applications. The mutually exclusive radical-catalyzed aerobic oxidation (the first step with MOF) and radical-inhibited autoxidation (the second step without MOF) are sequentially achieved in a one-pot manner. This MOF in-and-out method can be utilized in an environmentally friendly way for the oxidation of alcs. to carboxylic acids of industrial and economic value with broad functional group tolerance. Furthermore, MOF-TEMPO, as an antioxidative stabilizer, prevents the undesired oxidation of aldehydes. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8SDS of cas: 1777-82-8).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.SDS of cas: 1777-82-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts