Category: 16588-26-4

Computed Properties of C6H3BrClNO2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 3-Bromo-4-chloronitrobenzene, is researched, Molecular C6H3BrClNO2, CAS is 16588-26-4, about Ligand-free Suzuki-Miyaura cross-coupling with low Pd content: rapid development by a fluorescence-based high-throughput screening method. Author is Lim, Taeho; Ryoo, Jeong Yup; Jang, Mingyeong; Han, Min Su.

In this study, a highly efficient Suzuki-Miyaura (SM) cross-coupling was developed using metal oxide catalysts: 0.02 mol% Pd, aqueous solvent, no ligand, and room temperature Metal oxides containing low Pd content (ppm scale) were prepared by a simple co-precipitation method and used as a catalyst for the SM reaction. A fluorescence-based high-throughput screening (HTS) method was developed for the rapid evaluation of catalytic activity and reaction conditions. Among the various metal oxides, Pd/Fe2O3 showed the highest activity for the SM reaction. After further optimization by HTS, various biaryl compounds RR1 (R = 2-formylphenyl, 4-fluorophenyl, 2-chloro-5-nitrophenyl, etc.; R1 = Ph, 6-methoxynaphthalen-2-yl, pyren-1-yl, 4-fluoro-2-methylphenyl) were obtained under optimal conditions: Pd/Fe2O3 (0.02 mol% Pd) in aqueous ethanol at mild temperature without any ligands.

This literature about this compound(16588-26-4)Computed Properties of C6H3BrClNO2has given us a lot of inspiration, and I hope that the research on this compound(3-Bromo-4-chloronitrobenzene) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Electric Literature of C6H3BrClNO2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 3-Bromo-4-chloronitrobenzene, is researched, Molecular C6H3BrClNO2, CAS is 16588-26-4, about Formation and rearrangement of ipso intermediates in aromatic free-radical chlorination reactions. Author is Everly, Charles R.; Traynham, James G..

Photoinitiated chlorination of p-ClC6H4NO2 (I) in CCl4 at room temperature produces mainly p-Cl2C6H4 (II) and some Cl3C6H3 (III). Reaction of p-BrC6H4NO2 (IV) under the same conditions also produces II and III plus a small amount of 2,4-Br(O2N)C6H3Cl (V). The presence of rearrangement product V and the greater III/II ratio from IV than from I are strong evidence for the formation and rearrangement of an ipso intermediate in these aromatic free-radical chlorinations.

This literature about this compound(16588-26-4)Electric Literature of C6H3BrClNO2has given us a lot of inspiration, and I hope that the research on this compound(3-Bromo-4-chloronitrobenzene) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Highly Active and Chemoselective Reduction of Halogenated Nitroarenes Catalyzed by Ordered Mesoporous Carbon Supported Platinum Nanoparticles, published in 2019-05-06, which mentions a compound: 16588-26-4, mainly applied to reduction halogenated nitroarene catalyzed carbon platinum nanoparticle, Application In Synthesis of 3-Bromo-4-chloronitrobenzene.

Highly dispersed Pt nanoparticles (∼2.2 nm) on ordered mesoporous carbon (Pt/CMK-3-HQ) were first prepared through a two-step impregnation route with aqueous solutions of 8-hydroxyquinoline (8-HQ) and H2PtCl6, resp. The Pt/CMK-3-HQ quant. converted various halogenated nitroarenes to the corresponding haloanilines using hydrazine hydrate with unprecedented activities (e.g., turnover frequency for o-chloronitrobenzene was 30.2 s-1) and exhibited high stability with 20 cycles without decrease in catalytic efficiency. The high activity and chemoselectivity of Pt/CMK-3-HQ were attributed to the cooperation effect between Pt and N species, promoting cleavage of hydrazine to generate more Pt-H- and N-H+ species for reduction of nitro groups and weakening the interaction between halogen groups and Pt atoms for activation of C-halogen bonds.

This literature about this compound(16588-26-4)Application In Synthesis of 3-Bromo-4-chloronitrobenzenehas given us a lot of inspiration, and I hope that the research on this compound(3-Bromo-4-chloronitrobenzene) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Formula: C6H3BrClNO2. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 3-Bromo-4-chloronitrobenzene, is researched, Molecular C6H3BrClNO2, CAS is 16588-26-4, about Gold-catalyzed direct hydrogenative coupling of nitroarenes to synthesize aromatic azo compounds. Author is Liu, Xiang; Li, Hai-Qian; Ye, Sen; Liu, Yong-Mei; He, He-Yong; Cao, Yong.

The azo linkage is a prominent chem. motif which has found numerous applications in materials science, pharmaceuticals, and agrochems. Described herein is a sustainable heterogeneous-gold-catalyzed synthesis of azo arenes. Available nitroarenes are deoxygenated and linked selectively by the formation of N-N bonds using mol. H2 without any external additives. As a result of a unique and remarkable synergy between the metal and support, a facile surface-mediated condensation of nitroso and hydroxylamine intermediates is enabled, and the desired transformation proceeds in a highly selective manner under mild reaction conditions. The protocol tolerates a large variety of functional groups and offers a general and versatile method for the environmentally friendly synthesis of sym. or asym. aromatic azo compounds © 2014 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

This literature about this compound(16588-26-4)Formula: C6H3BrClNO2has given us a lot of inspiration, and I hope that the research on this compound(3-Bromo-4-chloronitrobenzene) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Gold-catalyzed direct hydrogenative coupling of nitroarenes to synthesize aromatic azo compounds, published in 2014, which mentions a compound: 16588-26-4, mainly applied to nitroarene hydrogenative coupling gold catalyst; diphenyldiazene green preparation; arenes; azo compounds; gold; reduction; supported catalysts, Application In Synthesis of 3-Bromo-4-chloronitrobenzene.

The azo linkage is a prominent chem. motif which has found numerous applications in materials science, pharmaceuticals, and agrochems. Described herein is a sustainable heterogeneous-gold-catalyzed synthesis of azo arenes. Available nitroarenes are deoxygenated and linked selectively by the formation of N-N bonds using mol. H2 without any external additives. As a result of a unique and remarkable synergy between the metal and support, a facile surface-mediated condensation of nitroso and hydroxylamine intermediates is enabled, and the desired transformation proceeds in a highly selective manner under mild reaction conditions. The protocol tolerates a large variety of functional groups and offers a general and versatile method for the environmentally friendly synthesis of sym. or asym. aromatic azo compounds © 2014 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

In addition to the literature in the link below, there is a lot of literature about this compound(3-Bromo-4-chloronitrobenzene)Application In Synthesis of 3-Bromo-4-chloronitrobenzene, illustrating the importance and wide applicability of this compound(16588-26-4).

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Quality Control of 3-Bromo-4-chloronitrobenzene. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 3-Bromo-4-chloronitrobenzene, is researched, Molecular C6H3BrClNO2, CAS is 16588-26-4, about In Situ Synthesized Silica-Supported Co@N-Doped Carbon as Highly Efficient and Reusable Catalysts for Selective Reduction of Halogenated Nitroaromatics. Author is Sheng, Yao; Wang, Xueguang; Yue, Shengnan; Cheng, Gonglin; Zou, Xiujing; Lu, Xionggang.

Silica-supported Co@N-doped carbon (Co@CN/SiO2) catalysts were first prepared by a one-step impregnation with a mixed solution of cobalt nitrate, glucose and urea, followed by in situ carbonization and reduction The Co@CN/SiO2 catalysts were investigated for the selective reduction of nitro aromatics RNO2 (R = Ph, 4,5-dichloro-2-nitroaniline, 2-chloro-3-nitropyridine, etc.) to the corresponding anilines RNH2 using hydrazine hydrate. The Co@CN/SiO2-500 carbonized at 500°C exhibited the highest catalytic activity and excellent stability without any decay of activity after 6 cycles for the reduction of nitrobenzene. Both metallic Co atoms and Co-N species formed in the Co@CN/SiO2 catalysts were active, but the Co-N species were dominant active sites. The high activities of the Co@CN/SiO2 catalysts were attributed to the synergistic effect between the Co and N atoms, promoting heterolytic cleavage of hydrazine to form H+/H- pairs. Representative examples demonstrated that the Co@CN/SiO2-500 could completely transform various halogen-substituted nitro aromatics to the corresponding halogenated anilines with high TOFs and selectivity of >99.5%.

In addition to the literature in the link below, there is a lot of literature about this compound(3-Bromo-4-chloronitrobenzene)Quality Control of 3-Bromo-4-chloronitrobenzene, illustrating the importance and wide applicability of this compound(16588-26-4).

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

HPLC of Formula: 16588-26-4. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 3-Bromo-4-chloronitrobenzene, is researched, Molecular C6H3BrClNO2, CAS is 16588-26-4, about Optimization of pyrimidinyl- and triazinyl-amines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Author is Thakur, Vinay V.; Kim, Joseph T.; Hamilton, Andrew D.; Bailey, Christopher M.; Domaoal, Robert A.; Wang, Ligong; Anderson, Karen S.; Jorgensen, William L..

Non-nucleoside inhibitors of HIV-1 reverse transcriptase are being pursued through synthesis and assaying for anti-viral activity. Following computational analyses, the focus has been on the motif Het-NH-Ph-U, where Het is an aromatic heterocycle and U is an unsaturated, hydrophobic group. Previous investigations with Het = 2-thiazoyl and 2-pyrimidinyl are extended here to triazinyl derivatives The result is several NNRTIs in the 2-20 nM range with negligible cytotoxicity and auspicious predicted pharmacol. properties.

In addition to the literature in the link below, there is a lot of literature about this compound(3-Bromo-4-chloronitrobenzene)HPLC of Formula: 16588-26-4, illustrating the importance and wide applicability of this compound(16588-26-4).

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kothare, Mohit A.; Ohkanda, Junko; Lockman, Jeffrey W.; Qian, Yimin; Blaskovich, Michelle A.; Sebti, Said M.; Hamilton, Andrew D. published an article about the compound: 3-Bromo-4-chloronitrobenzene( cas:16588-26-4,SMILESS:BrC1=C(C=CC(=C1)[N+](=O)[O-])Cl ).COA of Formula: C6H3BrClNO2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:16588-26-4) through the article.

This paper describes the development of a novel terphenyl-based tripeptide mimetic of the CAAX carboxy terminal sequence of Ras. We employ a concise synthesis to form a series of differently functionalized terphenyl inhibitors of protein farnesyltransferase (PFTase), exemplified by I [R = (S)-HSCH2CH(NH2)CH2- (II); R = HS-3-C6H4C(O)- (III); R = HSCH2CH2C(O)- (IV)]. The key reaction in the synthesis of the terphenyl Me ester, and therefore III and IV, was the Pd-catalyzed chemoselective Suzuki cross-coupling of 3-bromo-4-chloronitrobenzene with an appropriate boronic acid derivative utilizing a com. available, electron rich phosphine ligand. We further show that II is a potent inhibitor of PFTase.

In addition to the literature in the link below, there is a lot of literature about this compound(3-Bromo-4-chloronitrobenzene)COA of Formula: C6H3BrClNO2, illustrating the importance and wide applicability of this compound(16588-26-4).

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Metal-Free Reduction of Aromatic Nitro Compounds to Aromatic Amines with B2pin2 in Isopropanol》. Authors are Lu, Hongtao; Geng, Zhiyue; Li, Jingya; Zou, Dapeng; Wu, Yusheng; Wu, Yangjie.The article about the compound:3-Bromo-4-chloronitrobenzenecas:16588-26-4,SMILESS:BrC1=C(C=CC(=C1)[N+](=O)[O-])Cl).Safety of 3-Bromo-4-chloronitrobenzene. Through the article, more information about this compound (cas:16588-26-4) is conveyed.

A metal-free reduction of aromatic nitro compounds to the corresponding amines has been achieved by a combination of B2pin2 and KOtBu in isopropanol. A series of nitro compounds containing various reducible functional groups were chemoselectively reduced in good to excellent yields.

There are many compounds similar to this compound(16588-26-4)Safety of 3-Bromo-4-chloronitrobenzene. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.de Almeida, Leonardo S.; de Mattos, Marcio C. S.; Esteves, Pierre M. researched the compound: 3-Bromo-4-chloronitrobenzene( cas:16588-26-4 ).SDS of cas: 16588-26-4.They published the article 《Tribromoisocyanuric acid in trifluoroacetic acid: an efficient system for smooth brominating of moderately deactivated arenes》 about this compound( cas:16588-26-4 ) in Synlett. Keywords: aryl bromide preparation; arene bromination tribromoisocyanuric acid. We’ll tell you more about this compound (cas:16588-26-4).

Moderately deactivated arenes are efficiently brominated by the reaction with tribromoisocyanuric acid (0.34 mol equiv) in trifluoroacetic acid at room temperature in 48-85% isolated yield. This medium avoids the polybromination of the substrate, observed in the same reaction performed in 98% H2SO4.

In addition to the literature in the link below, there is a lot of literature about this compound(3-Bromo-4-chloronitrobenzene)SDS of cas: 16588-26-4, illustrating the importance and wide applicability of this compound(16588-26-4).

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts