Category: 1599840-16-0

On April 2, 2020, Xu, Jianyan; Zhang, Ying; Cai, Xiaofeng; Qu, Bolei; Liang, Jindong; Zhang, Lianshan; He, Feng; Tao, Weikang published a patent.Recommanded Product: 3-Cyclopropyl-2-hydroxypropanoic acid The title of the patent was Ligand-drug conjugate of exatecan analogue, preparation method therefor and application thereof. And the patent contained the following:

The present invention relates to a ligand-drug conjugate of an exatecan analog, a preparation method therefor and an application thereof. Specifically, the present invention provides a ligand-drug conjugate having a structure shown in formula (-D), a preparation method therefor, a pharmaceutical composition containing same, and use thereof in preparation of drugs for treating cancers by means of receptor regulation. The definition of each substituent in formula (-D) is the same as that in the description. The experimental process involved the reaction of 3-Cyclopropyl-2-hydroxypropanoic acid(cas: 1599840-16-0).Recommanded Product: 3-Cyclopropyl-2-hydroxypropanoic acid

The Article related to ligand drug conjugate exatecan analog, Pharmaceuticals: Formulation and Compounding and other aspects.Recommanded Product: 3-Cyclopropyl-2-hydroxypropanoic acid

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On September 30, 2021, Yue, Zhanlong; Yan, Zhen; Liu, Xun published a patent.Computed Properties of 1599840-16-0 The title of the patent was Pharmaceutical composition comprising antibody drug conjugate and use thereof. And the patent contained the following:

A pharmaceutical composition, comprising an antibody drug conjugate in a buffer solution The antibody drug conjugate has a structure represented by the general formula (Pc-L-Y-D). The pharmaceutical composition further comprises sugar and a surfactant. The experimental process involved the reaction of 3-Cyclopropyl-2-hydroxypropanoic acid(cas: 1599840-16-0).Computed Properties of 1599840-16-0

The Article related to antibody drug conjugate, Pharmaceuticals: Formulation and Compounding and other aspects.Computed Properties of 1599840-16-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On September 30, 2021, Liang, Zhi; Lin, Wenfeng; Shi, Ruijun; Liu, Xun published a patent.COA of Formula: C6H10O3 The title of the patent was Method for preparation and purification of antibody-drug conjugates having improved plasma stability and therapeutic effect for cancer therapy. And the patent contained the following:

Disclosed is a preparation method for an antibody medicament conjugate, comprising steps for synthesizing and purifying same. The experimental process involved the reaction of 3-Cyclopropyl-2-hydroxypropanoic acid(cas: 1599840-16-0).COA of Formula: C6H10O3

The Article related to sequence antibody drug conjugate improved stability effect cancer immunotherapy, Immunochemistry: Antibodies and Immunoglobulins and other aspects.COA of Formula: C6H10O3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On August 4, 2022, Li, Ao; Chen, Yile; Cao, Guoqing published a patent.COA of Formula: C6H10O3 The title of the patent was Toxin molecule suitable for antibody-drug conjugate. And the patent contained the following:

The present invention provides a toxin mol. suitable for an antibody-drug conjugate. In particular, the present invention provides a compound represented by structure I (X = H, OH, NH2, NHR0; Y = (CR1R2)n; Z = bond, carbonyl, thiocarbonyl, sulfonyl, etc.; R0 = C1-8 alkyl, haloalkyl, alkoxy, etc.; R1,R2 = H, D, halo, alkyl, etc.; R3,R4 = halo, C1-8 alkyl, haloalkyl, etc.; n = 0-3 integers). The claimed compound is prepared via multiple steps (procedure given). The prepared compound can be used in the preparation of a pharmaceutical composition for treating diseases associated with tumor cell proliferation. The experimental process involved the reaction of 3-Cyclopropyl-2-hydroxypropanoic acid(cas: 1599840-16-0).COA of Formula: C6H10O3

The Article related to toxin mol preparation antibody drug conjugate antitumor agent, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.COA of Formula: C6H10O3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts