In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 15753-50-1, name is cis-Cyclohexane-1,2-diyldimethanol, the common compound, a new synthetic route is introduced below. HPLC of Formula: C8H16O2
4) Preparation of ethyl 1-((2-tosyloxymethyl) cyclohexyl) carboxylate used at the start of Example 16. Formation of the Ester 2.23 ml of ethyl diazoacetate in solution in 16 ml of dichloromethane is added over 1 hour at ambient temperature to 3.06 g of cis 1,2-cyclohexane dimethanol in 100 ml of dichloromethane in the presence of a few drops of ethyl etherate borotrifluoride. The reaction medium is maintained under agitation for 16 hours at ambient temperature, followed by washing with water and drying, the solvent is evaporated off under reduced pressure, the residue is chromatographed on silica (eluant: AcOEt/cyclohexane 20-80) and 1.98 g of expected product is obtained.
The synthetic route of 15753-50-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Hoechst Marion Roussel; US6143774; (2000); A;,
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