Category: 156-87-6

Ren, Yiqing; Liu, Xinlong; Ge, Huan; Guo, Yuanyuan; Zhang, Qiushuang; Xie, Miao; Wang, Ping; Zhu, Xinyuan; Zhang, Chuan published an article in 2021. The article was titled 《A Combinatorial Approach Based on Nucleic Acid Assembly and Electrostatic Compression for siRNA Delivery》, and you may find the article in Chemical Research in Chinese Universities.COA of Formula: C3H9NO The information in the text is summarized as follows:

Acombinatorial strategy based on nucleic acid assembly and electrostatic complexation is developed for efficient small interfering RNA(siRNA) delivery. In this approach, siRNAs are first loaded into a well-defined nanotube through programmable nucleic acid self-assembly. Compared to small rigid siRNA duplex, the obtained siRNA-bearing nanotube with large architecture is more readily to complex with cationic and ionizable poly(β-amino ester), resulting in the formation of a novel platform for efficient siRNA delivery.3-Aminopropan-1-ol(cas: 156-87-6COA of Formula: C3H9NO) was used in this study.

3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic amines have the nitrogen atom connected to an aromatic ring.Important amines include amino acids, biogenic amines, trimethylamine, and aniline. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2).COA of Formula: C3H9NO

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In 2022,Liu, Xiaoyang; Bourret, Emmanuel; Noble, Cora A.; Cover, Kevin; Koenig, Ryan M.; Huang, Rong; Franklin, Hannah M.; Feng, Xu; Bodnar, Robert J.; Zhang, Fan; Tao, Chenggang; Sublett, D. Matthew Jr.; Dorn, Harry C.; Stevenson, Steven published an article in Journal of the American Chemical Society. The title of the article was 《Gigantic C120 Fullertubes: Prediction and Experimental Evidence for Isomerically Purified Metallic [5,5] C120-D5d(1) and Nonmetallic [10,0] C120-D5h(10766)》.Category: alcohols-buliding-blocks The author mentioned the following in the article:

We report the first exptl. characterization of isomerically pure and pristine C120 fullertubes, [5,5] C120-D5d(1) and [10,0] C120-D5h(10766). These new mols. represent the highest aspect ratio fullertubes isolated to date; for example, the prior largest empty cage fullertube was [5,5] C100-D5d(1). This increase of 20 carbon atoms represents a gigantic leap in comparison to three decades of C60-C90 fullerene research. Moreover, the [10,0] C120-D5d(10766) fullertube has an end-cap derived from C80-Ih and is a new fullertube whose C40 end-cap has not yet been isolated exptl. Theor. and exptl. analyses of anisotropic polarizability and UV-vis assign C120 isomer I as a [5,5] C120-D5d(1) fullertube. C120 isomer II matches a [10,0] C120-D5h(10766) fullertube. These structural assignments are further supported by Raman data showing metallic character for [5,5] C120-D5d(1) and nonmetallic character for C120-D5h(10766). STM imaging reveals a tubular structure with an aspect ratio consistent with a [5,5] C120-D5d(1) fullertube. With microgram quantities not amenable to crystallog., we demonstrate that DFT anisotropic polarizability, augmented by long-accepted exptl. analyses (HPLC retention time, UV-vis, Raman, and STM) can be synergistically used (with DFT) to down select, predict, and assign C120 fullertube candidate structures. From 10 774 math. possible IPR C120 structures, this anisotropic polarizability paradigm is quite favorable to distinguish tubular structures from carbon soot. Identification of isomers I and II was surprisingly facile, i.e., two purified isomers for two possible structures of widely distinguishing features. These metallic and nonmetallic C120 fullertube isomers open the door to both fundamental research and application development.3-Aminopropan-1-ol(cas: 156-87-6Category: alcohols-buliding-blocks) was used in this study.

3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.Category: alcohols-buliding-blocks

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《Is basicity the sole criterion for attaining high carbon dioxide capture in deep-eutectic solvents?》 was published in Physical Chemistry Chemical Physics in 2020. These research results belong to Shukla, Shashi Kant; Nikjoo, Dariush; Mikkola, Jyri-Pekka. HPLC of Formula: 156-87-6 The article mentions the following:

A critical anal. of the role of Hammett basicity (H-) and aqueous basicity (pKa) in CO2 uptake in deep-eutectic solvents (DESs) suggests that neither H- nor pKa correlates with the CO2 weight/% capacity in the studied DESs. Instead, strong “”synergistic interactions”” between donor and acceptor moieties satisfactorily relate to the weight/% of CO2 in DESs.3-Aminopropan-1-ol(cas: 156-87-6HPLC of Formula: 156-87-6) was used in this study.

3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. Hydrogen peroxide (H2O2) and peroxy acids generally add an oxygen atom to the nitrogen of amines. With primary amines, this step is normally followed by further oxidation, leading to nitroso compounds, RNO, or nitro compounds, RNO2. Secondary amines are converted to hydroxylamines, R2NOH, and tertiary amines to amine oxides, R3NO.HPLC of Formula: 156-87-6

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Fallica, Antonino Nicolo; Barbaraci, Carla; Amata, Emanuele; Pasquinucci, Lorella; Turnaturi, Rita; Dichiara, Maria; Intagliata, Sebastiano; Gariboldi, Marzia Bruna; Marras, Emanuela; Orlandi, Viviana Teresa; Ferroni, Claudia; Martini, Cecilia; Rescifina, Antonio; Gentile, Davide; Varchi, Greta; Marrazzo, Agostino published an article in 2021. The article was titled 《Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents》, and you may find the article in Journal of Medicinal Chemistry.Safety of 3-Aminopropan-1-ol The information in the text is summarized as follows:

The potential anticancer effect of fluoroquinolone antibiotics has been recently unveiled and related to their ability to interfere with DNA topoisomerase II. We herein envisioned the design and synthesis of novel Ciprofloxacin and Norfloxacin nitric oxide (NO) photo-donor hybrids to explore the potential synergistic antitumor effect exerted by the fluoroquinolone scaffold and NO eventually produced upon light irradiation Anticancer activity, evaluated on a panel of tumor cell lines, showed encouraging results with IC50 values in the low micromolar range. Some compounds displayed intense antiproliferative activity on triple-neg. and doxorubicin-resistant breast cancer cell lines, paving the way for their potential use to treat aggressive, refractory and multidrug-resistant breast cancer. No significant additive effect was observed on PC3 and DU145 cells following NO release. Conversely, antimicrobial photodynamic experiments on both Gram-neg. and Gram-pos. microorganisms displayed a significant killing rate in Staphylococcus aureus, accounting for their potential effectiveness as selective antimicrobial photosensitizers. The experimental part of the paper was very detailed, including the reaction process of 3-Aminopropan-1-ol(cas: 156-87-6Safety of 3-Aminopropan-1-ol)

3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.Safety of 3-Aminopropan-1-ol

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SDS of cas: 156-87-6In 2020 ,《Experimental Study of Some Thermodynamic Properties of Binary Mixtures Containing 3-Amino-1-propanol, 2-Aminoethanol, and 1-Butanol at Temperatures of 293.15-333.15 K to Model the Excess Molar Volumes Using the PFP Theory》 was published in Journal of Chemical & Engineering Data. The article was written by Kermanpour, Fakhri; Kheyrabadi, Zahra Gharagozlo. The article contains the following contents:

D., ρ, and viscosity, η, of pure components of 2-aminoethanol, 1-butanol, and 3-amino-1-propanol, along with the binary mixtures of {x12-aminoethanol + x21-butanol}, {x13-amino-1-propanol + x21-butanol}, and {x13-amino-1-propanol + x22-aminoethanol}, were determined over the whole composition range and in the temperatures of 293.15-333.15 at ambient pressure p = 86 kPa. The exptl. values of d. and viscosity have been used to calculate the excess molar volume, VmE, partial molar volumes, V̅1 and V̅2, excess partial molar volumes, V̅1E and V̅2E, thermal expansion coefficient, α, excess thermal expansion coefficient, αE, and viscosity deviation, Δη, of binary mixtures The results show that excess molar volumes of the mixtures are neg. in the whole composition range and increase with increasing temperature Viscosity deviations, Δη, of two former mixtures are neg. over the entire composition range and decrease with increasing temperature, while the Δη values of the later mixture are pos. over the entire composition range and decrease with the increasing temperature The excess properties were correlated by the Redlich-Kister equation, and their fitting parameters and standard deviations were determined The excess molar volumes were also correlated by applying the Prigogine-Flory-Patterson (PFP) model, and their interaction parameters, χ12, were obtained. In the experiment, the researchers used 3-Aminopropan-1-ol(cas: 156-87-6SDS of cas: 156-87-6)

3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.SDS of cas: 156-87-6

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HPLC of Formula: 156-87-6In 2022 ,《Structure-Activity Correlation Analyses of MEA + 3A1P/MAE Isomers with a Coordinative Effect Study》 was published in Industrial & Engineering Chemistry Research. The article was written by Shi, Huancong; Cheng, Xiaofang; Peng, Jiacheng; Feng, Hongliang; Yang, Xuan; Quan, Luoqiu; Jiang, Linhua; Tontiwachwuthikul, Paitoon. The article contains the following contents:

The “”coordinative effect””, which enhances absorption and desorption performance of single RR’NH at once, was verified repeatedly within MEA + BEA, MEA + DEA, and MEA + BEA + AMP. This work studied the “”coordinative effect”” within specific MEA + 3-amino-1-propanol 3A1P(RNH2) and MEA + 2-(methylamine)ethanol MAE(RR’NH). The amine 3A1P and MAE were isomers with the same formula but different mol. structures. Both CO2 absorption and desorption tests were conducted in bi-solvents MEA + 3A1P and MEA + MAE sep., with the help of CO2 absorption-desorption parameters. Exptl. results demonstrated that the “”coordinative effect”” existed within MEA + 3A1P and MEA + MAE. Both CO2 absorption/desorption performances of MEA + 3A1P/MAE were superior to those of 3A1P/MAE single amine simultaneously. The coordinative effect reached an optimum ratio for amine blends at 0.2-0.3 + 2 mol/L of MEA + 3A1P and 0.3 + 2 mol/L of MEA + MAE. Based on scientific anal., carbamate stability is the dominant factor contributing to strong or negligible coordinative effects of MEA + AMP and 3A1P. The synthesized MEA + RR’NH will be blended with other R3N/AMP to generate tri-solvents with a large concentration and cyclic capacities for industrial applications. In the experiment, the researchers used many compounds, for example, 3-Aminopropan-1-ol(cas: 156-87-6HPLC of Formula: 156-87-6)

3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.HPLC of Formula: 156-87-6

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《Design and synthesis of novel pyrrolo[2,3-b]pyridine derivatives targeting V600EBRAF》 was published in Bioorganic & Medicinal Chemistry in 2020. These research results belong to Abdel-Maksoud, Mohammed S.; Ali, Eslam M. H.; Ammar, Usama M.; Mersal, Karim I.; Yoo, Kyung Ho; Oh, Chang-Hyun. Reference of 3-Aminopropan-1-ol The article mentions the following:

Several pyrrolo[2,3-b]pyridine-based B-RAF inhibitors are well known and some of them are currently FDA approved as anticancer agents. Based on the structure of these FDA approved V600EB-RAF inhibitors, two series of pyrrolo[2,3-b]pyridine scaffold were designed and synthesized in attempt to develop new potent V600EB-RAF inhibitors. The 38 synthesized compounds were biol. evaluated for their V600EB-RAF inhibitory effect at single dose (10 μM). Compounds with high percent inhibition were tested to determine their IC50 over V600EB-RAF. Compounds 34e and 35 showed the highest inhibitory effect with IC50 values of 0.085 μM and 0.080 μM, resp. Headed for excessive biol. evaluation, the synthesized derivatives were tested over sixty diverse human cancer cell lines. Only compound 35(I) emerged as a potent cytotoxic agent against different panel of human cancer cell lines. In the experimental materials used by the author, we found 3-Aminopropan-1-ol(cas: 156-87-6Reference of 3-Aminopropan-1-ol)

3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. Amine, any member of a family of nitrogen-containing organic compounds that is derived, either in principle or in practice, from ammonia (NH3). Naturally occurring amines include the alkaloids, which are present in certain plants; the catecholamine neurotransmitters (i.e., dopamine, epinephrine, and norepinephrine); and a local chemical mediator, histamine, that occurs in most animal tissues.Reference of 3-Aminopropan-1-ol

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In 2019,Industrial & Engineering Chemistry Research included an article by Meng, Xiangzhan; Zhang, Yongqiang; Li, Zengxi; Wang, Hui; Zhang, Suojiang. Application of 156-87-6. The article was titled 《Selective Oxidation of Amino Alcohols to Amino Acids over Au Supported on Monoclinic ZrO2: Dominant Active Sites and Kinetic Study》. The information in the text is summarized as follows:

Au supported on monoclinic ZrO2 (Au/m-ZrO2) prepared by deposition-precipitation method showed excellent catalytic performance in the aerobic oxidation of amino alcs. to amino acids, i.e., glycine, alanine, serine, β-alanine, and 2-aminobutyric acid. The Au particle size and valence distribution of the gold species were adjusted by calcination temperature, as demonstrated by XRD, TEM, UV-vis DRS, XPS, and H2-TPR, which significantly influenced the catalytic activity but not the selectivity of amino acids. Metallic gold atoms on the surface were shown to be the active sites by the correlation between reaction rate per mol of metallic Au and Au particle size. The kinetics of oxidation of monoethanolamine (MEA) was studied in detail, and the results indicated that MEA oxidation is a first-order reaction with an activation energy of 52.8 kJ·mol-1. After reading the article, we found that the author used 3-Aminopropan-1-ol(cas: 156-87-6Application of 156-87-6)

3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. Halogenation, in which one or more hydrogen atoms of an amine is replaced by a halogen atom, occurs with chlorine, bromine, and iodine, as well as with some other reagents, notably hypochlorous acid (HClO). With primary amines the reaction proceeds in two stages, producing N-chloro- and N,N-dichloro-amines, RNHCl and RNCl2, respectively. With tertiary amines, an alkyl group may be displaced by a halogen.Application of 156-87-6

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The author of 《Heavy atom labeling enables silanol defect visualization in silicalite-1 crystals》 were Li, Teng; Krumeich, Frank; Ihli, Johannes; Ma, Zhiqiang; Ishikawa, Takashi; Pinar, Ana B.; van Bokhoven, Jeroen A.. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Safety of 3-Aminopropan-1-ol The author mentioned the following in the article:

Using heavy-atom labeling in conjunction with electron microscopy, the authors here visualize the distribution of point defects, i.e. internal silanol groups, in silicalite-1 zeolites at the single crystal level. In addition to this study using 3-Aminopropan-1-ol, there are many other studies that have used 3-Aminopropan-1-ol(cas: 156-87-6Safety of 3-Aminopropan-1-ol) was used in this study.

3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.Safety of 3-Aminopropan-1-ol

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《Fluorescence assay for the determination of D-panthenol based on novel ring-fused 2-pyridone derivative》 was written by Kasprzyk, Wiktor; Swiergosz, Tomasz; Koper, Filip. HPLC of Formula: 156-87-6 And the article was included in International Journal of Molecular Sciences in 2020. The article conveys some information:

Herein, a novel fluorescent method for the determination of D-panthenol (DP) level in solutions with no sep. hydrolysis step has been revealed based on the utilization of citric acid (CA) as a derivatizing agent. Consequently, the essential parameters of the derivatization process were established, resulting in the development of sensitive, repeatable, and accurate determination of panthenol. The method was approved, and its usefulness in characterizing the concentration of DP in pharmaceutical formulations and selectivity in the determination of DP were validated. The chem. structure of the new fluorophore formulating in the reaction in DP with CA, i.e., 6-oxo-3,4-dihydro-2H,6H-pyrido[2,1-b][1,3]oxazine-8-carboxylic acid (ODPC), was elucidated using detailed NMR experiments: one-dimensional (1H, 13C) as well as two-dimensional NMR spectra (1H-1H COSY, 1H-13C HSQC, 1H-13C HMBC, 1H-15N HSQC, 1H-15N HMBC). In addition to this study using 3-Aminopropan-1-ol, there are many other studies that have used 3-Aminopropan-1-ol(cas: 156-87-6HPLC of Formula: 156-87-6) was used in this study.

3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. Amines characteristically form salts with acids; a hydrogen ion, H+, adds to the nitrogen. With the strong mineral acids (e.g., H2SO4, HNO3, and HCl), the reaction is vigorous. Salt formation is instantly reversed by strong bases such as NaOH. Neutral electrophiles (compounds attracted to regions of negative charge) also react with amines; alkyl halides (R′X) and analogous alkylating agents are important examples of electrophilic reagents.HPLC of Formula: 156-87-6

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