Category: 1454-85-9

Reference of 1454-85-9 , The common heterocyclic compound, 1454-85-9, name is Heptadecan-1-ol, molecular formula is C17H36O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

In a 100 ml, 3 port reaction vessel equipped with a mechanical stirrer, mantle, thermowatch, short-column condenser, cow receiver, thermometers, and a nitrogen blanket, 27.68 grams of hydrophobe group containing compound and 4.34 grams of p-toluenesulfonic acid monohydrate were added. The reactants were heated to about 80° C. and 25 grams of the trithiocarbonate compound was added. A partial vacuum to 60 mmHg mercury was applied and the temperature was increased to about 110° C. for a period of five hours to produce the product shown above.

The synthetic route of 1454-85-9 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Lai, John Ta-Yuan; Hsu, Shui-Jen Raymond; Tamareselvy, Krishnan; US2006/39939; (2006); A1;,
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Reference of 1454-85-9, Adding some certain compound to certain chemical reactions, such as: 1454-85-9, name is Heptadecan-1-ol,molecular formula is C17H36O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1454-85-9.

General procedure: To a cooled (0 C) solution of alcohol(1.0 mmol) in anhydrous dichloromethane (5 ml), triethylamine (2.0 mmol),methoxyacetyl chloride (1.5 mmol) and dimethylaminopyridine (0.1 mmol)were added. The reaction mixture was stirred for 12?16 h at rt. The reactionmass was diluted with water and extracted with dichloromethane. The organiclayer was washed with 1 N HCl, saturated sodium bicarbonate, brine and driedover anhydrous sodium sulphate. The solvent was evaporated and purificationwas carried out by flash column chromatography.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 1454-85-9, Heptadecan-1-ol, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Gadekar, Pradip K.; Hoermann, Maryann; Corbo, Faith; Sharma, Rajiv; Sarveswari; Roychowdhury, Abhijit; Tetrahedron Letters; vol. 55; 2; (2014); p. 503 – 506;,
Alcohol – Wikipedia,
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Related Products of 1454-85-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1454-85-9, name is Heptadecan-1-ol. This compound has unique chemical properties. The synthetic route is as follows.

General procedure: Compound 1 (590mg, 1.0mmol), which was prepared from protoporphyrin IX (PPIX) under acid esterification conditions,17 was dissolved in HBr/acetic acid (25percent, 30mL) under nitrogen atmosphere and the mixture was stirred for 2h. All volatile solvents were evaporated under vacuum to yield dimethyl 3,3?-(7,12-bis(1-bromoethyl)-3,8,13,17-tetramethylporphyrin-2,18-diyl)dipropionate (2) as a green colored liquid. The resulting liquid was directly dissolved in dichloromethane (50mL), and 1-tridecanol (2.2mmol, 441mg) and Cs2CO3 (2.2mmol, 304mg) were added to the dichloromethane solution. The reaction mixture was again stirred under nitrogen atmosphere for 2h and filtered. The resulting filtrate was concentrated under the reduced pressure and the residue was purified by preparative TLC on silica gel with CH2Cl2/MeOH (20:1) to give compound 3a (218mg, 23percent yield) as a dark violet crystal. Rf=0.8 (CH2Cl2/MeOH 20:1); 1H NMR (400MHz, CDCl3, TMS) delta 10.63 (s, 1H), 10.61 (s, 1H), 10.11 (s, 1H), 10.08 (s, 1H), 6.09 (m, 2H), 4.41?4.45 (m, 4H), 3.73 (s, 3H), 3.71 (s, 3H), 3.70 (s, 3H), 3.69 (s, 3H), 3.68 (s, 3H) 3.67 (s, 3H), 3.65 (m, 4H), 3.28?3.32 (m, 4H), 2.25?2.27 (d, J=7.0Hz, 6H), 1.09?1.80 (m, 42H), 0.84 (t, J=12.9Hz, 6H); 13C NMR (75MHz, CDCl3, TMS) delta 173.7 (2C; C=O), 140.6, 140.4, 138.4, 138.2, 137.2, 136.8, 136.5 (16C; C pyrrole), 98.8, 98.6, 96.8, 96.1, 73.3 (2C, OCH) 69.6 (2C, OCH2), 51.74 (2C; CO2CH3), 37.0 (2C, CH3CH), 31.9 (2C; CH2COOMe), 30.3, 29.5, 29.3, 26.4, 25.5, (24C; ?CH2?), 22.6 (2C; CH2CH2COO), 21.9, 14.1 (2C, CH3C pyrrole), 11.7ppm (2C; CH3C pyrrole); IR (NaCl disc) 3311, 2924, 2853, 1739, 1435, 1100cm?1; MS (ESI, positive): m/z (percent): 991; HRMS (ESI, positive) m/z Calcd for C62H94N4O6 [M+H]+; 991.7252, found: 991.7252.

According to the analysis of related databases, 1454-85-9, the application of this compound in the production field has become more and more popular.

Reference:
Article; Tachikawa, Shoji; El-Zaria, Mohamed E.; Inomata, Ryu; Sato, Shinichi; Nakamura, Hiroyuki; Bioorganic and Medicinal Chemistry; vol. 22; 17; (2014); p. 4745 – 4751;,
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Electric Literature of 1454-85-9, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.1454-85-9, name is Heptadecan-1-ol, molecular formula is C17H36O, molecular weight is 256.4672, as common compound, the synthetic route is as follows.

General procedure: The D1-OCn (n =15-21) were prepared as reported previously.22,23 The alkyl alcohol (1mmol) with triethylamine (2mmol) was added to isobutenyl binaphthyl di(acid chloride) (0.5mmol) in THF, and stirred at 60 °C for 1 day. After the evaporation of the solvent, the product was purified by silica gel column chromatography with CHCl3 as an eluent.

The chemical industry reduces the impact on the environment during synthesis 1454-85-9, I believe this compound will play a more active role in future production and life.

Reference:
Article; Kikkawa, Yoshihiro; Ishitsuka, Manami; Omori, Kazuhiro; Kashiwada, Ayumi; Tsuzuki, Seiji; Hiratani, Kazuhisa; Bulletin of the Chemical Society of Japan; vol. 88; 6; (2015); p. 834 – 842;,
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Reference of 1454-85-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1454-85-9, name is Heptadecan-1-ol. This compound has unique chemical properties. The synthetic route is as follows.

To an ice-cold solution of heptadecanol (2.0 g, 7.8 mmole) in methylenechloride (20 rut) and TEA (3 rat, 20 rumole) was added the abovesuspension of acid chloride (9.3 mmole) in nethylene chloride (20 mL). After stirring for 10 ninutes at ice bath tenperature, the ice?bath was removed and stirring continued at room temperature for 4 h. The reaction mixture was then washed with water (2 x 8 mL) followed bybrine (10 mL), dried over anhydrous sodium sulfate, filtered and concentrated. The crude residue was purified by column chromatography using 5percent methanol in methylene chloride to give the pure required compound 17 (1.1 g, 27percent) as a off white solid, m.p.llo?112¡ã C. ?H NHR (CDC13) 5 0.87 (t, d, .1=7.2 Hz, 3H), 1.24 (m, 28H), 1.40?1.51 (m, 4H),1.60?1.79 (m, 2H), 2.55 (s,3H), 2.75 (m, 3H), 2.85?3.06 (m, 4H),3.60?3.85 (m,3H), 4.03(t, d, J=7.2 Hz, 2H), 4.88 (m,1H), 4.94(m,lH); ESMS:507 (H+H)

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1454-85-9, Heptadecan-1-ol.

Reference:
Patent; LIXTE BIOTECHNOLOGY, INC.; KOVACH, John, S.; JOHNSON, Francis; SAMUDRALA, Ramakrishna; GUPTA, Ramesh, C.; WO2015/73802; (2015); A1;,
Alcohol – Wikipedia,
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Electric Literature of 1454-85-9, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 1454-85-9, name is Heptadecan-1-ol. A new synthetic method of this compound is introduced below.

General procedure: Alcohol (1.0 eq.) and sodium hydride (60percent in mineral oil, 2.8 eq.) were introduced in dimethoxyethane (10 mL). The solution was refluxed up to the end of H2 emission. Then, a solution of (2,2-dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate (1.4 eq.) in ethane-1,2-diol was added and the mixture was refluxed for 48 h. After cooling to room temperature, the solution was poured into water. The organic layer was extracted with diethyl ether and dried over Na2SO4. The solvents were removed under vacuum and the desired product was obtained after a purification by flash chromatography in chloroform. The advancement of the purification was followed by TLC in chloroform/acetone (90:10).

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1454-85-9, its application will become more common.

Reference:
Article; Pinault, Michelle; Guimaraes, Cyrille; Couthon, Helene; Thibonnet, Jerome; Fontaine, Delphine; Chantome, Aurelie; Chevalier, Stephan; Besson, Pierre; Jaffres, Paul-Alain; Vandier, Christophe; Marine Drugs; vol. 16; 4; (2018);,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts