Category: 126456-43-7

Safety of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-olIn 2019 ,《Preparation of 1,3-Thiazolidine-2-thiones by Using Potassium Ethylxanthate as a Carbon Disulfide Surrogate》 was published in Synlett. The article was written by Lu, Zheng; Yang, Yong-Qing; Xiong, Weixiang. The article contains the following contents:

A simple procedure is presented for preparing 1,3-thiazolidine-2-thiones, e.g., I by using potassium ethylxanthate and the corresponding β-amino alcs. as the starting materials in the presence of ethanol. The experimental part of the paper was very detailed, including the reaction process of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Safety of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol)

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime.Typically the presence of an amine functional group is deduced by a combination of techniques, including mass spectrometry as well as NMR and IR spectroscopies. 1H NMR signals for amines disappear upon treatment of the sample with D2O. In their infrared spectrum primary amines exhibit two N-H bands, whereas secondary amines exhibit only one.Safety of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol

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The author of 《Synthesis of Chiral Triazole-Based Halogen Bond Donors》 were Kaasik, Mikk; Kaabel, Sandra; Kriis, Kadri; Jarving, Ivar; Kanger, Tonis. And the article was published in Synthesis in 2019. Application In Synthesis of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol The author mentioned the following in the article:

The simple click chem. was applied for the straightforward synthesis of enantiomerically pure mono- and bidentate as well as multifunctional iodotriazole-based halogen bond donors I [R1 = (R,R)-2-acylaminocyclohexyl, acyl = MeCO, t-BuCO, PhCO, R2 = Ph; R1 = (1S,2R)-2-hydroxyindenyl, L-menthyl; R2 = 3,5-(F3C)2C6H3; etc.] and II. The methodol. is characterized by a wide variability due to easy access to chiral azides. In addition to this study using (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol, there are many other studies that have used (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Application In Synthesis of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol) was used in this study.

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Hydrogen peroxide (H2O2) and peroxy acids generally add an oxygen atom to the nitrogen of amines. With primary amines, this step is normally followed by further oxidation, leading to nitroso compounds, RNO, or nitro compounds, RNO2. Secondary amines are converted to hydroxylamines, R2NOH, and tertiary amines to amine oxides, R3NO.Application In Synthesis of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol

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《Indan-f-amphox: an efficient PNN ligand for iridium-catalyzed asymmetric hydrogenation of β-aryl β-ketoestersã€?was published in Youji Huaxue in 2020. These research results belong to Gu, Guoxian; Hu, Yang; Liu, Shaodong; Dong, Xiuqin; Zhang, Xumu. SDS of cas: 126456-43-7 The article mentions the following:

A new chiral tridentate PNN ligand, indan-f-amphox (a sister ligand of f-amphox), was synthesized and applied in iridium-catalyzed asym. hydrogenation of β-aryl β-ketoesters. A wide range of β-aryl β-ketoesters are reduced using an Ir (III)-indan-f-amphox catalyst with excellent enantioselectivities and reactivities (up to 99% ee, TON=10000). In addition to this study using (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol, there are many other studies that have used (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7SDS of cas: 126456-43-7) was used in this study.

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.SDS of cas: 126456-43-7

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《Thiocarbonyl Surrogate via Combination of Sulfur and Chloroform for Thiocarbamide and Oxazolidinethione Constructionã€?was written by Tan, Wei; Wei, Jianpeng; Jiang, Xuefeng. Name: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-olThis research focused onthiourea preparation; amine chloroform sulfur coupling; oxazolidinethione preparation; aminoalc chloroform sulfur coupling. The article conveys some information:

An efficient and practical thiocarbonyl surrogate via combination of sulfur and chloroform has been developed. A variety of thiocarbamides and oxazolidinethiones have been established, including chiral thiourea catalysts and chiral oxazolidinethione auxiliaries with high selectivity. Meanwhile, pesticides Diafenthiuron (an acaricide), ANTU (a rodenticide), and Chloromethiuron (an insecticide) were practically synthesized through this method in gram scale. Dicholorocarbene, as the key intermediate, was further confirmed via a carbene-trapping control experiment After reading the article, we found that the author used (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Name: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol)

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Acylation is one of the most important reactions of primary and secondary amines; a hydrogen atom is replaced by an acyl group (a group derived from an acid, such as RCOOH or RSO3H, by removal of ―OH, such as RC(=O)â€? RS(O)2â€? and so on). Reagents may be acid chlorides (RCOC1, RSO2C1), anhydrides ((RCO)2O), or even esters (RCOORâ€?; the products are amides of the corresponding acids.Name: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol

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In 2022,Mansawat, Woraluk; Yukhet, Phanomsak; Bhanthumnavin, Worawan; Reiser, Oliver; Vilaivan, Tirayut published an article in Synlett. The title of the article was 《Kinetic Resolution of dl-Hydrobenzoins Catalyzed by Copper(II) Complexes of C2-Symmetric Thiophene-Derived Ligandsã€?SDS of cas: 126456-43-7 The author mentioned the following in the article:

C2-Sym. chiral amino alc. ligands with a central thiophene moiety were shown to be effective in combination with CuCl2 for the asym. acylation of dl-hydrobenzoins. In contrast to previously developed chiral ligands, readily available acetyl chloride and acetic anhydride can be used as reagents, in addition to benzoyl chloride, giving rise to the corresponding monoacylated products in up to 99% ee ( S= 532). The experimental process involved the reaction of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7SDS of cas: 126456-43-7)

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Acylation is one of the most important reactions of primary and secondary amines; a hydrogen atom is replaced by an acyl group (a group derived from an acid, such as RCOOH or RSO3H, by removal of ―OH, such as RC(=O)â€? RS(O)2â€? and so on). Reagents may be acid chlorides (RCOC1, RSO2C1), anhydrides ((RCO)2O), or even esters (RCOORâ€?; the products are amides of the corresponding acids.SDS of cas: 126456-43-7

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2018,Yang, Xing; Cao, Ze-Hun; Zhou, Yang; Cheng, Feng; Lin, Zi-Wei; Ou, Zhi; Yuan, Ye; Huang, Yi-Yong published 《Petasis-Type gem-Difluoroallylation Reactions Assisted by the Neighboring Hydroxyl Group in Aminesã€?Organic Letters published the findings.Related Products of 126456-43-7 The information in the text is summarized as follows:

A three-component Petasis-type gem-difluoroallylation reaction of using pinacol gem-difluoroallylboronates, aldehydes or isatin, and β-amino alcs. enabled by the neighboring hydroxyl group in amine is reported, affording various racemic and chiral gem-difluorohomoallylamine derivatives with good to excellent results. Based on the control experiment and stereochem. of the product, a proposed reaction pathway is illustrated to clarify the origin of regio- and stereoselectivity under protic solvent conditions.(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Related Products of 126456-43-7) was used in this study.

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Amines characteristically form salts with acids; a hydrogen ion, H+, adds to the nitrogen. With the strong mineral acids (e.g., H2SO4, HNO3, and HCl), the reaction is vigorous. Salt formation is instantly reversed by strong bases such as NaOH. Neutral electrophiles (compounds attracted to regions of negative charge) also react with amines; alkyl halides (R′X) and analogous alkylating agents are important examples of electrophilic reagents.Related Products of 126456-43-7

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《Titanium complexes containing tridentate [ONO] type Schiff base ligands for the cycloaddition reaction of CO2 to propylene oxideã€?was written by Byun, Young Min; Lee, Ji Min; Ryu, Ji Yeon; Go, Min Jeong; Na, Kyung Su; Kim, Youngjo; Lee, Junseong. Recommanded Product: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-olThis research focused ontitanium hydroxyindanylaminopentenone complex preparation cycloaddition catalyst; crystal structure titanium hydroxyindanylaminopentenone. The article conveys some information:

New titanium complexes, TiLCl2(THF) and TiL2, containing the tridentate chiral Schiff-base ligand, L, prepared from the condensation reaction of 2,4-pentadione and (1R,2S)-(-)-1-aminoindanol, were synthesized and characterized by various anal. methods including X-ray crystallog. Ligand L acted as a dianionic tridentate ligand and, owing to a chiral center in the aminoindanol part, imparted chirality to its titanium complexes. The newly synthesized titanium complexes and previously reported analogous Ti complexes were used as catalysts in the cycloaddition of CO2 to propylene oxide as the first representatives of titanium complexes with tridentate Schiff base ligands to have been used for this purpose. These complexes provided high selectivity toward cyclic propylene carbonate (>99%) and showed considerable activities with TOF values up to 131 h-1 in comparison with the previously reported catalyst systems. After reading the article, we found that the author used (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Recommanded Product: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol)

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Recommanded Product: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol

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In 2018,Fujiki, Katsumasa; Tanaka, Katsunori published 《Bis[ N , N ‘-(2-indanolyl)]-1,5-diazacyclooctane as Unique Metal Ligand: Self-Assembly of Palladium Nanoparticles and Catalytic Reactivity on C-C Bond Formationã€?Synthesis published the findings.Application of 126456-43-7 The information in the text is summarized as follows:

A previously unreported 1,5-diazacyclooctane-palladium(II) complex was synthesized using bis[ N, N’-(2-indanolyl)]-1,5-diazacyclooctane, which was readily prepared via a novel [4+4] homocyclization of the unsaturated imine intermediate generated from acrolein and 1-amino-2-indanol. Interestingly, the 1,5-diazacyclooctane-palladium(II) complex self-assembled to form palladium nanoparticles. This approach readily provided palladium nanoparticles simply by heating a mixture of palladium(II) acetate and bis[ N, N’-(2-indanolyl)]-1,4-diazacyclooctane in dichloroethane at mild temperatures The 1,5-diazacyclooctane-derivative-palladium nanoparticles were successfully deployed in synthetic applications as a heterogeneous catalyst, facilitating Suzuki coupling and a challenging C-C bond formation via C(sp 3)-H activation under low catalyst loading conditions.(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Application of 126456-43-7) was used in this study.

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.Application of 126456-43-7

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In 2018,Meng, Fei-Fan; Xie, Jia-Hao; Xu, Yun-He; Loh, Teck-Peng published 《Catalytically asymmetric synthesis of 1,3-bis(silyl)propenes via copper-catalyzed double proto-silylations of polar enynesã€?ACS Catalysis published the findings.Name: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol The information in the text is summarized as follows:

A copper-catalyzed (CuCl2/bpy) double proto-silylations of electron-deficient conjugated enynes RCH:CHCCX (X = CO2Me, CN, COCH2CH2Ph) with silylboronate PhMe2SiBpin to synthesize functional bis(silyl)propenes (E)-RCH(SiMe2Ph)CH:C(SiMe2Ph)CH2X (3; R = aryl, alkyl, thienyl) was developed. Under mild reaction conditions, the silylboronate PhMe2Si-Bpin reacts with the enynes via cascade proto-silylations and yields the corresponding Z-specific bis(silyl)propene products in up to 98% yield and 95% ee. In addition, the use instead of bipyridines chiral enantiopure substituted and annelated 2-pyridyloxazoles resulted in enantioselective synthesis of the compounds (3) was also achieved. In the experiment, the researchers used (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Name: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol)

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Milder oxidation, using reagents such as NaOCl, can remove four hydrogen atoms from primary amines of the type RCH2NH2 to form nitriles (R―C≡N), and oxidation with reagents such as MnO2 can remove two hydrogen atoms from secondary amines (R2CH―NHRâ€? to form imines (R2C=NRâ€?. Tertiary amines can be oxidized to enamines (R2C=CHNR2) by a variety of reagents.Name: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol

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Morack, Tobias; Onneken, Carina; Nakakohara, Hiroshi; Mueck-Lichtenfeld, Christian; Gilmour, Ryan published their research in ACS Catalysis in 2021. The article was titled 《Enantiodivergent Prenylation via Deconjugative Isomerizationã€?Name: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol The article contains the following contents:

A light-enabled deconjugative isomerization of activated alkenes containing an aryl ketone antenna, e.g., (E)-2,4-dimethyl-1-phenylpent-2-en-1-one is disclosed through sequential geometric isomerization/hydrogen atom transfer (HAT)/protonation. Detailed mechanistic analyses have guided the development of an enantioselective variant of this atom economical process (up to 99% and 95:5 e.r.). Importantly, the chiral pool quasi-enantiomers quinine and quinidine serve as effective catalysts, thereby rendering this addition to the chiral drug discovery module portfolio enantiodivergent. In addition to this study using (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol, there are many other studies that have used (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Name: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol) was used in this study.

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Amines have a free lone pair with which they can coordinate to metal centers. Amine–metal bonds are weaker because amines are incapable of backbonding, but they are still important for sensing applications.While stronger than hydrogen bonds, amine–metal bonds are still weaker than both covalent and ionic bonds.Name: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol

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