Category: 124-76-5

Guo, Weihong published the artcileMajor constituents of cannabis vape oil liquid, vapor and aerosol in California vape oil cartridge samples, Computed Properties of 124-76-5, the main research area is cannabis vape oil liquid vapor aerosol major constituent GCMS; EVALI (e-cigarette or vaping product use-associated lung injury); GC-MS; aerosol; delta-9 tetrahydrocannabinol; nontarget; toxin; vape oil; vapor.

During the E-cigarette or Vaping product use Associated Lung Injury (EVALI) outbreak of August 2019 to Feb. 2020, the California Department of Public Health, Food and Drug Laboratory Branch received numerous cannabis vape oil cartridge investigation samples from throughout the state. Many of these products were directly linked to patients; others were collected as part of investigations. We determined the major ingredients and additives in twelve unused cannabis vape oil cartridge samples obtained before (n = 2) and during the EVALI outbreak (n = 10) in California from Sept. 2018 to Dec. 2019. We tested for major constituents in vape oil liquid, vape oil vapor, and vape oil aerosol phases. A nontargeted Gas Chromatog. Mass Spectrometry direct injection screening method was developed for vape oils, a headspace heating module used for vape oil vapors and a solid-phase microextraction (SPME) vaping rig for aerosols generated by vaping. We have identified more than 100 terpenes and natural extracts, 19 cannabinoids, and other potential toxic additives such as Vitamin E Acetate, Polyethylene Glycols, and Medium Chain Triglycerides. We determined more terpenes and minor cannabinoids can be produced via vaporizing and aerosolizing the vape oil. Delta9-THC and potential toxic additives were found at lower levels in the vapor and aerosol than in the vape liquid

Frontiers in Chemistry (Lausanne, Switzerland) published new progress about Aerosols. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Computed Properties of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yu, Hang published the artcileExtraction of Cinnamomum camphora chvar. Borneol essential oil using neutral cellulase assisted-steam distillation: optimization of extraction, and analysis of chemical constituents, Product Details of C10H18O, the main research area is Cinnamomum camphora borneol essential oil.

In this study, neutral cellulase assisted-steam distillation (NCSD) was first developed to extract BEO, followed by optimizing NCSD through single-factor test (SFT) and response surface methodol. (RSM). The processing conditions of NCSD were optimized as follows: addition of neutral cellulase (0.36 FPU/g of fresh leaves), duration of enzymolysis (5.39 h), temperature (51.47°C), and pH (6.15). The predicted yield of BEO using NCSD was 1.03% within 95% confidence intervals of the actual yield of BEO (1.03 ± 0.03%), which was 58% higher than the yield of BEO using conventional steam distillation (SD) without neutral cellulase pre-treatment (0.65 ± 0.04%). Moreover, chem. constituents of BEO using NCSD and SD were evaluated and compared. Results show that 62 volatile compounds were identified, and majority of functional compounds in the BEO using NCSD and SD were detected simultaneously, e.g. borneol, β-pinene, and β-cadinene. A significantly higher proportion of compounds with relatively lower mol. weight (MW) ranging from 130 to 150 and higher MW ranging from 205 to 225 were detected in the BEO using NCSD, which may contribute to a stronger flavoring impact and influence the overall flavor profile of the BEO. Therefore, significance of this study is to develop the NCSD as a more effective method than the SD for extracting the BEO from Cinnamomum camphora chvar. Borneol fresh leaves without compromising its quality and remaining the majority of chem. consitutents unchanged.

Industrial Crops and Products published new progress about Cell wall. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Product Details of C10H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wei, Chaozhi published the artcileThe characteristics of patulin detoxification by Lactobacillus plantarum 13M5, Safety of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is lactobacillus plantarum patulin characteristic detoxification; Degradation; Lactic acid bacteria; Lactobacillus plantarum; Patulin; Toxicity.

Patulin (PAT) is a widespread mycotoxin that harms the health of both humans and animals. In this study, among the 17 tested Lactobacillus plantarum strains, L. plantarum 13M5, isolated from traditional Chinese fermented foods, showed the highest PAT degradation rate of up to 43.8% (PAT 5 mg/L). Evaluation of the living and dead 13M5 cells revealed that only the living cells had the ability to remove PAT and degrade it into E-ascladiol. A cell-based assay revealed that L. plantarum 13M5 administration alleviated PAT-induced injuries in Caco-2 cells, including cytotoxicity, oxidative stress, and tight junction disruption. Our results suggest that L. plantarum 13M5 has the potential to reduce PAT toxicity and can thus be used as a probiotic supplement to reduce or eliminate the toxicity of PAT ingested from diet.

Food and Chemical Toxicology published new progress about Apoptosis. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Safety of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

van Vuuren, S. published the artcileIndigenous South African essential oils as potential antimicrobials to treat foot odour (bromodosis), Quality Control of 124-76-5, the main research area is foot odor therapy essential oil antimicrobial.

Foot odor, known as bromodosis, is produced as a result of a combination of exocrine secretions and bacterial growth on the feet. Several com. essential oils have demonstrated promise in inhibiting the growth of odor-causing bacteria as a novel strategy to offer relief from this dermatol. problem. South Africa harbours an abundance of diverse indigenous flora which has shown favorable antimicrobial properties. As such, the potential application of natural products against bromodosis-causing Brevibacterium species with the aim of finding cosmetically appealing and promising African sourced essential oils capable of masking foot malodour was the focus of this study. The antimicrobial activity of 41 oils were investigated using the microdilution assay where the min. inhibitory concentrations (MICs) were reported against Brevibacillus agri (ATCC 51663), Brevibacillus epidermidis (DSM 20660) and Brevibacillus linens (DSM 20425). Ninety-five percent of the oils tested displayed noteworthy activity (MIC ≤ 1.00 mg/mL) against B. agri with S. africana-caerulea demonstrating the highest activity (0.03 mg/mL) overall. Thirty-one essential oils displayed noteworthy activity (MIC ≤ 1.00 mg/mL) against B. epidermidis. Two essential oils (Plectranthus grandidentatus and Salvia africana-lutea) displayed noteworthy activity (MIC = 1.00 mg/mL) against B. linens. The major constituents for each oil was determined using gas chromatog. coupled to mass spectrometry and limonene appears to be the most frequent essential oil constituent (23 of the oils). The olfactory properties of the essentials oils displaying noteworthy activity were further considered. These findings presenting interesting anti-bromodosis activity hold great potential, as not only do the selected oils have antimicrobial activity, but the pleasant aroma of these aromatic botanicals can further mask and control foot odor.

South African Journal of Botany published new progress about Agathosma. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Quality Control of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Purcaro, Giorgia published the artcileBreath metabolome of mice infected with Pseudomonas aeruginosa, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is metabolome breath volatile organic compound Pseudomonas infection; Breath; Comprehensive gas chromatography-time-of-flight mass spectrometer (GC×GC ToF MS); Pseudomonas aeruginosa; Volatile organic compounds (VOCs).

The measurement of specific volatile organic compounds in breath has been proposed as a potential diagnostic for a variety of diseases. The most well-studied bacterial lung infection in the breath field is that caused by Pseudomonas aeruginosa. To determine a discriminatory core of mols. in the “”breath-print”” of mice during a lung infection with four strains of P. aeruginosa (PAO1, PA14, PAK, PA7). Furthermore, we attempted to extrapolate a strain-specific “”breath-print”” signature to investigate the possibility of recapitulating the genetic phylogenetic groups (Stewart et al. Pathog Dis 71(1), 20-25, 2014. https://doi.org/10.1111/2049-632X.12107). Breath was collected into a Tedlar bag and shortly after drawn into a thermal desorption tube. The latter was then analyzed into a comprehensive multidimensional gas chromatog. coupled with a time-of-flight mass spectrometer. Random forest algorithm was used for selecting the most discriminatory features and creating a prediction model. Three hundred and one mols. were significantly different between animals infected with P. aeruginosa, and those given a sham infection (PBS) or inoculated with UV-killed P. aeruginosa. Of those, nine metabolites could be used to discriminate between the three groups with an accuracy of 81%. Hierarchical clustering showed that the signature from breath was due to a specific response to live bacteria instead of a generic infection response. Furthermore, we identified ten addnl. volatile metabolites that could differentiate mice infected with different strains of P. aeruginosa. A phylogram generated from the ten metabolites showed that PAO1 and PA7 were the most distinct group, while PAK and PA14 were interspersed between the former two groups. To the best of our knowledge, this is the first study to report on a core murine breath print, as well as, strain level differences between the compounds in breath. We provide identifications (by running com. available anal. standards) to five breath compounds that are predictive of P. aeruginosa infection.

Metabolomics published new progress about Algorithm. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Singh, Nagender published the artcileNovel Chitosan-Gelatin microcapsules containing rosemary essential oil for the preparation of bioactive and protective linen, HPLC of Formula: 124-76-5, the main research area is chitosan gelatin linen fabric microcapsule rosemary essential oil.

Biomols. present in natural materials have always remained a prime choice for the development of safe, protective, and wellness-related textile products. In this study, functional microcapsules were prepared using the chitosan-gelatin complex as a shell material and rosemary essential oil as a core material. The prepared microcapsules were utilized for the development of multifunctional linen fabric. The oil release mechanism of microcapsules was studied using the Korsmeyer-Peppas model. The obtained microcapsules and finished linen fabrics were characterized using SEM-EDX anal. and ATR-FTIR anal. The durability of functionalities against repeated launderings was also studied. The microcapsules with an encapsulation efficiency of more than 70% were used to impart durable mosquito-repellency (more than 90%) against Anopheles mosquitoes, antibacterial properties against E. coli (> 93%) and S. aureus (> 95%) bacteria, significant (> 91%) antioxidant activity and a pleasant aroma. The chem. constituents of rosemary oil were also found to be responsible for imparting multifunctional properties. The novel combination of biopolymers and essential oil was explored for the development of multifunctional textiles.

Industrial Crops and Products published new progress about Anopheles. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, HPLC of Formula: 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hayashi, Hiroyuki published the artcileInsight into the Mechanism of the Acylation of Alcohols with Acid Anhydrides Catalyzed by Phosphoric Acid Derivatives, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is alc acylation carboxylic acid anhydride phosphoric acid derivative catalysis.

Insight into the mechanism of a safe, simple, and inexpensive phosphoric acid (H3PO4)-catalyzed acylation of alcs. with acid anhydrides is described. The corresponding in situ-generated diacylated mixed anhydrides, unlike traditionally proposed monoacylated mixed anhydrides, are proposed as the active species. In particular, the diacylated mixed anhydrides act as efficient catalytic acyl transfer reagents rather than as Bronsted acid catalysts simply activating acid anhydrides. Remarkably, highly efficient phosphoric acid (1-3 mol %)-catalyzed acylation of alcs. with acid anhydrides was achieved and a 23 g scale synthesis of an ester was demonstrated. Also, phosphoric acid catalyst was effective for synthetically useful esterification from carboxylic acids, alcs., and acid anhydride. Moreover, with regard to recent developments in chiral 1,1′-bi-2-naphthol (BINOL)-derived phosphoric acid diester catalysts toward asym. kinetic resolution of alcs. by acylation, some phosphate diesters were examined As a result, a 31P NMR study and a kinetics study strongly supported not only the acid-base cooperative mechanism as previously proposed by other researchers but also the mixed anhydride mechanism as presently proposed by us.

Journal of Organic Chemistry published new progress about Acylation. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ezzarrouqy, Kamal published the artcileStudy of the energetic, exergetic, and thermal balances of a solar distillation unit in comparison with a conventional system during the distillation of rosemary leaves, Quality Control of 124-76-5, the main research area is energetic exergetic thermal balance solar distillation rosemary leaf; Butane gas; Energy; Exergy; Rosemary; Solar distillation system; Steam line.

The solar energy produced by Scheffler parabola (10 m2) is not fully exploited by the solar distillation system of aromatic and medicinal plants. In this work, the optical losses in the primary and secondary reflectors, and the thermal losses at each part of this system (solar still, steam line, condenser) were determined A thermal energetic and exergetic anal. were also performed for a solar distillation system of rosemary leaves. For average intensity radiation of 849.1W/m2 and 6 Kg of rosemary leaves during 4 h of distillation, exergy and optical efficiencies of the system achieved up to 26.62% and 50.97%, resp. The thermal efficiency of the solar still, steam line, and condenser is about 94.80%, 94.30%, and 87.76%, resp. The essential oil yield per unit of consumed energy and the total efficiency of the solar distillation system, taking into account the heat losses in the solar still, steam line, and condenser, as well as the optical losses in the two reflectors, is 6.18 mL/ kWh and 40.00%, resp. The efficiency can be as high as 42.42% if the steam line is insulated. Moreover, the comparison between the solar steam distillation and conventional steam distillation shows that solar distillation is much more efficient since it gives better results and especially it avoids the emission of 12.10 kg of CO2 during extraction

Environmental Science and Pollution Research published new progress about Condensers. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Quality Control of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yu, Meina published the artcileSteric group-based polymer dispersed liquid crystal composite films with high contrast ratio, low driving voltage and small hysteresis, Product Details of C10H18O, the main research area is liquid crystal composite film voltage small hysteresis.

The unique phase-separated microstructure has endowed polymer dispersed liquid crystals (PDLCs) with outstanding electro-optical performances. However, their applications are hampered by the high driving voltage and low contrast ratio. Attempts to optimize the materials have been made in order to reduce the driving voltage without sacrificing the contrast ratio and other features. Herein, acrylate monomers with different steric end groups were introduced to fabricate PDLCs and their effects on the electro-optical properties and microstructure were investigated. Bipolar droplet configuration was observed in all samples implying tangential anchoring conditions. It was found that the steric end group could affect the morphol. of polymer matrix and the electro-optical properties. By carefully adjusting the steric group and doping concentration, the contrast ratio could be enhanced and the driving voltage could be reduced. Besides, hysteresis could also be decreased. The research offers more choices for the construction of PDLCs from material perspective, promoting their potential applications.

Journal of Molecular Liquids published new progress about Composites. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Product Details of C10H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Junka, Adam published the artcilePotential of Biocellulose Carrier Impregnated with Essential Oils to Fight Against Biofilms Formed on Hydroxyapatite, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Staphylococcus Pseudomonas essential oil d cadinene cellulose hydroxyapatite biofilm.

In this research, bacterial cellulose (BC), one of the most promising biopolymers of the recent years, was saturated with thyme, eucalyptus and clove essential oils (EOs) and applied against staphylococcal and pseudomonal biofilms formed on hydroxyapatite (HA). BC dressings were thoroughly analyzed with regard to their phys. properties. Moreover, the exact composition and ability of particular EO mols. to adhere to HA was assessed. Addnl., cytotoxicity of oil-containing, cellulose-based dressings towards osteoblasts and fibroblasts as well as their impact on reactive oxygen species (ROS) production by macrophages was assessed. The results revealed the high ability of BC dressings to absorb and subsequently release EOs from within their microstructure; the highest number of compounds able to adhere to HA was found in the thyme EO. The eucalyptus EO displayed low, while thyme and clove EOs displayed high cytotoxicity towards fibroblast and osteoblast cell lines. The clove EO displayed the highest eradication ability toward staphylococcal, while the thyme EO against pseudomonal biofilm. Taken together, the results obtained indicate the suitability of EO-saturated BC dressings to eradicate pseudomonal and staphylococcal biofilm on HA surface and moreover, to not trigger reactive oxygen species production by immune system effector cells. However, due to cytotoxic effects of thyme and clove EOs towards cell lines in vitro, the eucalyptus EO-saturated BC dressing is of highest potential to be further applied.

Scientific Reports published new progress about Antagonism. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts