Category: 124-76-5

Gyorgy, Zsuzsanna published the artcileDifferentiating Thymus vulgaris chemotypes with ISSR molecular markers, HPLC of Formula: 124-76-5, the main research area is ISSR mol marker thymus vulgaris chemotype genetic diversity.

Common thyme (Thymus vulgaris L.) is a Mediterranean evergreen shrub of the Lamiaceae that shows chem. polymorphism in its natural populations. In Mediterranean habitats six basic chemotypes have been described according to the main component in its essential oil: thymol, carvacrol, linalool, geraniol, α-terpineol, thuyanol-4, of which the thymol chemotype is widely used in cultivation and as a spice. In this study ten selected clones were analyzed in terms of chem. composition of the volatile oil and genetic fingerprint. The study question was whether individual chemotypes can be distinguished by mol. markers. Chem. composition was analyzed by GC-MS, and for assessing the genetic polymorphism ISSR marker system was chosen as it is reliable and easy to use even in case of less studied species. The studied T. vulgaris clones represented five different chemotypes and could be distinguished using 12 ISSR primers. Clones belonging to the thymol chemotype showed the most distinct separation The study shows the potential of using mol. markers in breeding and selection of T. vulgaris, being able to differentiate different chemotypes.

Biochemical Systematics and Ecology published new progress about Animal breeding. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, HPLC of Formula: 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lin, Shifan published the artcileStudy on the Effect of Mentha x piperita L. Essential Oil on Electroencephalography upon Stimulation with Different Visual Effects, Category: alcohols-buliding-blocks, the main research area is Mentha piperita essential oil electroencephalog stimulation visual effect; colour; electroencephalograph; inhalation; peppermint essential oil.

Essential oils have long been used to fight infections and treat various diseases. Peppermint (Mentha x piperita L.) is an herbal medicine that has been widely used in daily life since ancient times, and it has a wide range of applications in food, cosmetics, and medicine. Mint oil is refreshing because of its cool and comfortable smell; therefore, it is often used in ethnopharmacol. studies. The present study investigated the effects of peppermint essential oil in electroencephalog. activity response to various visual stimuli. The electroencephalog. changes of participants during peppermint essential oil inhalation under white, red, and blue color stimulations were recorded. A rapid Fourier transform anal. was used to examine the electroencephalograph power spectra of the various microstates induced by inhaling the oils. Peppermint essential oil had various effects on the brain when subjected to different visual stimuli. Alpha waves increased in the prefrontal area in the white-sniffing group, which facilitated learning and thinking. In the blue-sniffing group, the changes were less pronounced than those in the red group, and the increased alpha wave activity in the occipital area was more controlled, indicating that the participants’ visual function increased in this state. Based on EEG investigations, this is the first study to indicate that vision influences the effects of peppermint essential oils. Hence, the results of this study support the use of essential oils in a broader context to serve as a resource for future studies on the effects of different types of essential oils.

Molecules published new progress about Ayurveda. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ugbabe, Grace E. published the artcileChemo-microscopy of the leaves and GC-MS analyses of oils from different parts of Lantana camara linn grown in Nigeria, Application of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Lantana camara linn chemomicroscopy GCMS analyses.

Chemo-microscopic anal. of Lantana camara Linn revealed the presence of lignin, starch, cellulose, oxalate crystals, tannin, oils, proteins and absence of mucilage in the leaves while the flowers showed the presence of all tested metabolites except mucilage and lignin. The GC-MS anal. of volatile oils of different parts (leaves, flowers, fruits) obtained by hydro-distillation was carried out. The total components detected in the oil of the leaf were 48, the flower oil had 49, and the fruit oil had 14 compounds, the major components common in the parts studied were: eucalyptol, beta-caryophyllene and alpha-caryophyllene. The components with the highest percentage compositions in the leaves were: gamma-terpinene (10.24%), eucalyptol (9.36%), alpha-pinene (5.82%), beta-caryophyllene (5.13%). In the flowers the components that had the highest composition were: eucalyptol (7.65%), trans-nerolidol (7.17%), beta-caryophyllene (6.95%), sabinene (6.29%), 14-hexadecatetraenyl acetate (5.82%), alpha-caryophyllene (5.81%) and in the fruits the components that had the highest composition were: phytol (23.04%), octadec-9-enoic acid (15.50%), beta-caryophyllene (13.57%), sabinene (9.66%), nhexadecanoic acid (9.51%), alpha-caryophyllene (6.97%) and trans-nerolidol (6.93%). The chemo-microscopic and GC-MS characterization of Lantana camara can be used for identification and quality control of the L. camara as a crude drug. Volatile oil constituents found in the different parts of the plant find applications in flavorings, fragrances or perfumery, cough suppressant, manufacture of cosmetic products, manufacture of detergents, soaps, emulsifying agent, manufacture of synthetic vitamin E and vitamin K1 as well as antiinflammatory, anti-bacterial and anti-fungal agents and manufacture of aerosol product and insecticides.

European Journal of Biomedical and Pharmaceutical Sciences published new progress about Aerosols. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Application of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Guo, Weihong published the artcileMajor constituents of cannabis vape oil liquid, vapor and aerosol in California vape oil cartridge samples, Computed Properties of 124-76-5, the main research area is cannabis vape oil liquid vapor aerosol major constituent GCMS; EVALI (e-cigarette or vaping product use-associated lung injury); GC-MS; aerosol; delta-9 tetrahydrocannabinol; nontarget; toxin; vape oil; vapor.

During the E-cigarette or Vaping product use Associated Lung Injury (EVALI) outbreak of August 2019 to Feb. 2020, the California Department of Public Health, Food and Drug Laboratory Branch received numerous cannabis vape oil cartridge investigation samples from throughout the state. Many of these products were directly linked to patients; others were collected as part of investigations. We determined the major ingredients and additives in twelve unused cannabis vape oil cartridge samples obtained before (n = 2) and during the EVALI outbreak (n = 10) in California from Sept. 2018 to Dec. 2019. We tested for major constituents in vape oil liquid, vape oil vapor, and vape oil aerosol phases. A nontargeted Gas Chromatog. Mass Spectrometry direct injection screening method was developed for vape oils, a headspace heating module used for vape oil vapors and a solid-phase microextraction (SPME) vaping rig for aerosols generated by vaping. We have identified more than 100 terpenes and natural extracts, 19 cannabinoids, and other potential toxic additives such as Vitamin E Acetate, Polyethylene Glycols, and Medium Chain Triglycerides. We determined more terpenes and minor cannabinoids can be produced via vaporizing and aerosolizing the vape oil. Delta9-THC and potential toxic additives were found at lower levels in the vapor and aerosol than in the vape liquid

Frontiers in Chemistry (Lausanne, Switzerland) published new progress about Aerosols. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Computed Properties of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, Zhirui published the artcileNetwork pharmacology-based dissection of the underlying mechanisms of dyspnoea induced by zedoary turmeric oil, Formula: C10H18O, the main research area is network pharmacol dyspnoea zedoary turmeric oil; binding affinity; dyspnoea; haemoglobin; network pharmacology; zedoary turmeric oil.

Zedoary turmeric oil (ZTO) has been widely used in clinic. However, the unpleasant induced dyspnoea inevitably impedes its clin. application. Thus, it is urgent to elucidate the mechanism underlying the ZTO-induced dyspnoea. In this study, network pharmacol. was firstly performed to search the clue of ZTO-induced dyspnoea. The key target genes of ZTO-induced dyspnoea were analyzed using GO enrichment anal. and KEGG pathway anal. GO anal. suggested that haem binding could be a key mol. function involved in ZTO-induced dyspnoea. Hence, the Hb (Hb) was focused for its oxygen-carrying capacity with haem as its critical component binding to the oxygen. UV-visible absorption spectrum indicated that the ZTO injection (ZTOI) perturbed the Soret band of Hb, suggesting an interaction between ZTO and Hb. GC-MS anal. revealed that β-elemene, germacrone, curdione and furanodiene were main components of ZTOI. Mol. docking was used to illustrate the high affinity between representative sesquiterpenes and Hb, which was finally confirmed by surface plasmon resonance, suggesting their potential roles in dyspnoea by ZTO. Following a network pharmacol.-driven strategy, our study revealed an intervened Hb-based mechanism underlying the ZTO-induced dyspnoea, providing a reference for elucidating mechanism underlying adverse drug reactions of herbal medicines in clinic.

Basic & Clinical Pharmacology & Toxicology published new progress about Affinity. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Formula: C10H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Safaeian Laein, Sara published the artcileEvaluation of antibacterial and antioxidant activities of essential oil of lime (Citrus aurantifolia) pomace powder, Computed Properties of 124-76-5, the main research area is Citrus aurantifolia pomace essential oil antioxidant antibacterial activity.

This study aimed to determine the chem. compounds, antioxidant and antimicrobial activities of Essential Oil (EO) derived from lime pomace. Gas chromatog./mass spectrometry (GC-MS) was used to determine the major components of the obtained EO. The antioxidant activities of this EO were determined by radical scavenging activity (DPPH) and the Ferric Reducing Antioxidant Power (FRAP) test. For antimicrobial activity, the disk diffusion method was used and the Min. Inhibitory Concentrations (MIC) and the Min. Bactericidal Concentration (MBC) were studied against common foodborne pathogens including; Staphylococcus aureus, Bacillus cereus, Listeria monocytogenes, Escherichia coli, Salmonella typhimurium, and Pseudomonas aeruginosa. The result showed that the Gram-pos. bacteria were more susceptible than gram-neg. bacteria. The result shows that lime pomace powder with IC50 83.061 mg/mL has a high antioxidant capacity and also, the chem. anal. of the EO showed that the EO contained a complex mixture of several components and the main constituents were D-limonene (28.86%), a- terpinene (15.65%) and D-terpinene (12.72%) resp.

Iranian Journal of Chemistry & Chemical Engineering published new progress about Analysis. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Computed Properties of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yu, Hang published the artcileExtraction of Cinnamomum camphora chvar. Borneol essential oil using neutral cellulase assisted-steam distillation: optimization of extraction, and analysis of chemical constituents, Product Details of C10H18O, the main research area is Cinnamomum camphora borneol essential oil.

In this study, neutral cellulase assisted-steam distillation (NCSD) was first developed to extract BEO, followed by optimizing NCSD through single-factor test (SFT) and response surface methodol. (RSM). The processing conditions of NCSD were optimized as follows: addition of neutral cellulase (0.36 FPU/g of fresh leaves), duration of enzymolysis (5.39 h), temperature (51.47°C), and pH (6.15). The predicted yield of BEO using NCSD was 1.03% within 95% confidence intervals of the actual yield of BEO (1.03 ± 0.03%), which was 58% higher than the yield of BEO using conventional steam distillation (SD) without neutral cellulase pre-treatment (0.65 ± 0.04%). Moreover, chem. constituents of BEO using NCSD and SD were evaluated and compared. Results show that 62 volatile compounds were identified, and majority of functional compounds in the BEO using NCSD and SD were detected simultaneously, e.g. borneol, β-pinene, and β-cadinene. A significantly higher proportion of compounds with relatively lower mol. weight (MW) ranging from 130 to 150 and higher MW ranging from 205 to 225 were detected in the BEO using NCSD, which may contribute to a stronger flavoring impact and influence the overall flavor profile of the BEO. Therefore, significance of this study is to develop the NCSD as a more effective method than the SD for extracting the BEO from Cinnamomum camphora chvar. Borneol fresh leaves without compromising its quality and remaining the majority of chem. consitutents unchanged.

Industrial Crops and Products published new progress about Cell wall. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Product Details of C10H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Purcaro, Giorgia published the artcileBreath metabolome of mice infected with Pseudomonas aeruginosa, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is metabolome breath volatile organic compound Pseudomonas infection; Breath; Comprehensive gas chromatography-time-of-flight mass spectrometer (GC×GC ToF MS); Pseudomonas aeruginosa; Volatile organic compounds (VOCs).

The measurement of specific volatile organic compounds in breath has been proposed as a potential diagnostic for a variety of diseases. The most well-studied bacterial lung infection in the breath field is that caused by Pseudomonas aeruginosa. To determine a discriminatory core of mols. in the “”breath-print”” of mice during a lung infection with four strains of P. aeruginosa (PAO1, PA14, PAK, PA7). Furthermore, we attempted to extrapolate a strain-specific “”breath-print”” signature to investigate the possibility of recapitulating the genetic phylogenetic groups (Stewart et al. Pathog Dis 71(1), 20-25, 2014. https://doi.org/10.1111/2049-632X.12107). Breath was collected into a Tedlar bag and shortly after drawn into a thermal desorption tube. The latter was then analyzed into a comprehensive multidimensional gas chromatog. coupled with a time-of-flight mass spectrometer. Random forest algorithm was used for selecting the most discriminatory features and creating a prediction model. Three hundred and one mols. were significantly different between animals infected with P. aeruginosa, and those given a sham infection (PBS) or inoculated with UV-killed P. aeruginosa. Of those, nine metabolites could be used to discriminate between the three groups with an accuracy of 81%. Hierarchical clustering showed that the signature from breath was due to a specific response to live bacteria instead of a generic infection response. Furthermore, we identified ten addnl. volatile metabolites that could differentiate mice infected with different strains of P. aeruginosa. A phylogram generated from the ten metabolites showed that PAO1 and PA7 were the most distinct group, while PAK and PA14 were interspersed between the former two groups. To the best of our knowledge, this is the first study to report on a core murine breath print, as well as, strain level differences between the compounds in breath. We provide identifications (by running com. available anal. standards) to five breath compounds that are predictive of P. aeruginosa infection.

Metabolomics published new progress about Algorithm. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Singh, Nagender published the artcileNovel Chitosan-Gelatin microcapsules containing rosemary essential oil for the preparation of bioactive and protective linen, HPLC of Formula: 124-76-5, the main research area is chitosan gelatin linen fabric microcapsule rosemary essential oil.

Biomols. present in natural materials have always remained a prime choice for the development of safe, protective, and wellness-related textile products. In this study, functional microcapsules were prepared using the chitosan-gelatin complex as a shell material and rosemary essential oil as a core material. The prepared microcapsules were utilized for the development of multifunctional linen fabric. The oil release mechanism of microcapsules was studied using the Korsmeyer-Peppas model. The obtained microcapsules and finished linen fabrics were characterized using SEM-EDX anal. and ATR-FTIR anal. The durability of functionalities against repeated launderings was also studied. The microcapsules with an encapsulation efficiency of more than 70% were used to impart durable mosquito-repellency (more than 90%) against Anopheles mosquitoes, antibacterial properties against E. coli (> 93%) and S. aureus (> 95%) bacteria, significant (> 91%) antioxidant activity and a pleasant aroma. The chem. constituents of rosemary oil were also found to be responsible for imparting multifunctional properties. The novel combination of biopolymers and essential oil was explored for the development of multifunctional textiles.

Industrial Crops and Products published new progress about Anopheles. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, HPLC of Formula: 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wei, Chaozhi published the artcileThe characteristics of patulin detoxification by Lactobacillus plantarum 13M5, Safety of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is lactobacillus plantarum patulin characteristic detoxification; Degradation; Lactic acid bacteria; Lactobacillus plantarum; Patulin; Toxicity.

Patulin (PAT) is a widespread mycotoxin that harms the health of both humans and animals. In this study, among the 17 tested Lactobacillus plantarum strains, L. plantarum 13M5, isolated from traditional Chinese fermented foods, showed the highest PAT degradation rate of up to 43.8% (PAT 5 mg/L). Evaluation of the living and dead 13M5 cells revealed that only the living cells had the ability to remove PAT and degrade it into E-ascladiol. A cell-based assay revealed that L. plantarum 13M5 administration alleviated PAT-induced injuries in Caco-2 cells, including cytotoxicity, oxidative stress, and tight junction disruption. Our results suggest that L. plantarum 13M5 has the potential to reduce PAT toxicity and can thus be used as a probiotic supplement to reduce or eliminate the toxicity of PAT ingested from diet.

Food and Chemical Toxicology published new progress about Apoptosis. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Safety of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts