Category: 124-76-5

Hou, Kexin published the artcileAqueous enzymatic pretreatment ionic liquid-lithium salt based microwave-assisted extraction of essential oil and procyanidins from pinecones of Pinus koraiensis, COA of Formula: C10H18O, the main research area is ionic liquid lithium Pinus essential oil procyanidin enzymic pretreatment.

In this study, in order to simultaneously extract procyanidins and essential oil from pinecones of Pinus koraiensis, aqueous enzymic pretreatment ionic liquid-lithium salt based microwave-assisted extraction (AEILLME) with a modified hydrodistillation concatenated Soxhlet extraction apparatus was proposed. 1-Butyl-3-methylimidazolium bromide solution was selected as extraction solvent, while LiCl and mixture of cellulase and pectinase (1:1, weight/weight) as additives by single factor experiment Other parameters that affect the yield of target components were investigated and optimized by Plackett-Burman design and Box-Behnken design. The obtained optimal conditions were: microwave irradiation power 581.49 W, microwave irradiation time 15.95 min and liquid-solid ratio 11.91 mL/g. Under the optimized conditions, the predicted yields of oligomeric procyanidins, polymeric procyanidins and essential oil were 13.02, 32.19 and 7.76 mg/g, resp. Anal. of chem. constituents in the essential oil was performed on gas chromatog.-mass spectrometry and there was no significant difference on the components of essential oil obtained by proposed method and traditional methods. Ionic liquids were successfully recycled and reused, which could lower the process cost and being beneficial to industrial production This study provides an approach with good prospects for the application in extracting active components from natural plant material.

Journal of Cleaner Production published new progress about Essential oils Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, COA of Formula: C10H18O.

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bisht, M. published the artcileEffect of natural drying methods on flavour profile of camphor rich Ocimum americanum L. from North India, Safety of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Ocimum essential oil natural drying method camphor flavor India.

In the present study, fresh aerial parts of Ocimum americanum L. were collected from Ramnagar, India and sun and shade drying was applied until constant weights The fresh and dried plant materials were hydrodistd. by Clevenger apparatus and the extracted oils were analyzed by GC and GC/MS. One-way ANOVA and correlation were performed to evaluate the difference and correlation between drying treatments using SPSS 16.0. The major compounds of the fresh oil were camphor (33.41%), maillol (11.96%), β-selinene (8.34%), α- selinene (6.92%), β-gurjunene (5.43%) and (E)-caryophyllene (5.07%). In the dried samples, significant increase (p < 0.05) in the percentage of camphor and maillol was observed while the percentage of (E)-cayophyllene, β-gurjunene, β-selinene and α-selinene significantly (p < 0.05) decreased during drying process. Drying caused loss of fourteen constituents with appearance of four compounds The oil yield was the highest under sun drying condition. Asian Journal of Chemistry published new progress about Essential oils Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Safety of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Trendafilova, Antoaneta published the artcileEssential Oil Composition of Five Thymus Species from Bulgaria, Quality Control of 124-76-5, the main research area is Thymus essential oil composition Bulgaria; PCA and CA; Sect. Hyphodromi; Thymus species; chemotypes; essential oils.

In this study, the essential oil composition of five Thymus species, belonging to Sect. Hyphodromi (A. Kerner) Halacsy – Thymus atticus Celak., T. leucotrichus Halacsy, T. striatus Vahl, T. zygioides Griseb. and T. perinicus (Velen.) Jalas. was studied by GC/MS/FID. T. atticus, T. leucotrichus, and T. striatus were characterized by high amounts of sesquiterpenoids (57.7, 78.9 and 79.7%, resp.) with β-caryophyllene and caryophyllene oxide as the main constituents. Aromatic compounds (61.2%) were the most abundant group in T. zygioides essential oil, with thymol (51.2%) as the principal component. The essential oil from the endemic species T. perinicus contained almost equal amounts of monoterpenoids (37.8%) and aromatic compounds (36.0%) with borneol (17.9%) and thymol (20.9%) as the major components. The obtained results revealed the existence of new chemotypes of T. atticus (caryophyllene oxide/β-caryophyllene), T. leucotrichus (β-caryophyllene/elemol/germacrene D) and T. striatus (β-caryophyllene/germacrene D/caryophyllene oxide). The essential oil content of endemic T. perinicus is reported for the first time. Principal component anal. (PCA) and cluster anal. (CA) were used to investigate the variations in the essential oils of different Thymus species from Sect. Hyphodromi (A. Kerner) Halacsy.

Chemistry & Biodiversity published new progress about Essential oils Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Quality Control of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wu, Xiang published the artcileMetabolomics revealing the response of rice (Oryza sativa L.) exposed to polystyrene microplastics, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Oryza polystyrene microplastics metabolomics; Metabolites disturbance; Microplastics; Polystyrene; Rice.

Large amounts of microplastics accumulate in the agricultural soil. Herein, a laboratory exposure and field trials were carried out to investigate the response of rice (Oryza sativa L. II You. 900) to stress induced by polystyrene microplastics (PS-MPs) using a metabolomic approach. After laboratory exposure for 21 days, the decreases in shoot biomass of rice exposed to low, medium and high doses of PS-MPs were 13.1% (CV = 4.1%), 18.8% (CV = 3.7%), and 40.3% (CV = 9.2%), resp., while the antioxidant enzymes showed an inverted upper-U shape when exposed to PS-MPs. A total of 24 samples from three exposure dose levels were included in the metabolic anal. The metabolites of 12 amino acids, 16 saccharides, 26 organic acids and 17 others (lipids and polyols) in leaves decreased after the exposure to both 50 mg L-1 and 250 mg L-1 PS-MPs doses with hydroponically-cultured. The inhibition of perturbed biol. pathway causes the biosynthesis of amino acids, nucleic acids, fatty acids and some secondary metabolites decreased which indicate that the energy expenditure exceeded the substance accumulation. After 142 days of cultivation in farmland, the results with a maximum of 25.9% lower biomass in the crops exposed with PS-MPs. As such, the presence of PS-MPs may affect rice production by altering the metabolic systems of rice. Long-term exposure of PS-MPs to rice might be a potential risk to rice safety and quality.

Environmental Pollution (Oxford, United Kingdom) published new progress about Amines, compounds Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Luan, Chunning published the artcileEffect of two-step fermentation with lactic acid bacteria and Saccharomyces cerevisiae on key chemical properties, molecular structure and flavor characteristics of horseradish sauce, Name: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is horseradish sauce lactic acid bacteria Saccharomyces cerevisiae flavor.

To enhance the quality or, in other words, increase the variety of horseradish sauce, two-step fermentation using lactic acid bacteria (LAB) and Saccharomyces cerevisiae is proposed for the production of the sauce. Total phenolics, acids and amino acid nitrogen contents were determined and used to assess the fermentation efficiency, while antioxidant activities, profiles of amino acids and volatile flavor compounds was used to indicate the quality of the sauce. Mol. structure determination as well as electronic tongue and sensory analyses were also conducted. Adding S. cerevisiae after 48 h of LAB fermentation resulted in higher fermentation efficiency. The sauce was noted to be fermented more fully, with increased content of amino acids by 23.10% compared with unfermented samples; its DPPH radical scavenging ability and reducing power increased by 26.26% and 33.33%, resp. The contents of alcs., esters and acids increased in the sauce. The electronic tongue and sensory evaluation showed that the sauce had good sensory quality.

LWT–Food Science and Technology published new progress about Acids Role: BUU (Biological Use, Unclassified), BIOL (Biological Study), USES (Uses). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Name: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Waris, Muhammad Irfan published the artcileMolecular and in vitro biochemical assessment of chemosensory protein 10 from brown planthopper Nilaparvata lugens at acidic pH, Computed Properties of 124-76-5, the main research area is mol in vitro biochem assessment chemosensory protein; Nilaparvata lugens acidic pH.

Chemosensory proteins (CSPs) are important mol. components of the insect olfactory system, which are involved in capturing, binding, and transporting hydrophobic odor mols. across the sensillum in sensillar lymph in regulating insect behavior. This protein family (CSPs) is also involved in many other systems that are not linked to olfactory receptors in olfactory sensilla. The brown planthopper (BPH) is a monophagous pest of rice that causes damage by sucking phloem sap and transmitting a number of diseases caused by viruses. In this study, fluorescence competitive binding assay and fluorescence quenching assay at acidic pH were performed as well as homol. modeling to describe the binding affinity of NlugCSP10. Fluorescence competitive binding assay (FCBA) demonstrated that NlugCSP10 bound strongly to nonadecane, farnesene, and 2-tridecanone at acidic pH. The results of FCBA indicated that NlugCSP10 bound different ligands at the physiol. pH (5.0) of the bulk sensillum lymph. Fluorescence quenching assay demonstrated that NlugCSP10 generated a stable complex with 2-tridecanone, while two ligands nonadecane and farnesene collided due to mol. collisions. The interaction of selected ligands with the modeled structure of NlugCSP10 was also analyzed, which found the key amino acids (Gln23, Gln24, Gln25, Asn27, Met33, Ser34, Ile35, Tyr36, Asn42, Met43, Val45, Asn46, Asn93, Arg96, Ala97, Lys99, and Ala100) in NlugCSP10 that were involved in binding of volatile compounds The present study contributes to the binding profile of NlugCSP10 that promotes the development of behaviorally active ligands based on BPH olfactory system.

Journal of Integrative Agriculture published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study) (Ala97). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Computed Properties of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Brown, Alistair K. published the artcileValidated quantitative cannabis profiling for Canadian regulatory compliance – Cannabinoids, aflatoxins, and terpenes, Application In Synthesis of 124-76-5, the main research area is cannabinoid aflatoxin terpene determination LC MS cannabis; Aflatoxins; Cannabis; Chromatography; Mass spectrometry; Quantitative method; Terpenes.

In response to the Canadian federal government’s Cannabis Tracking and Licensing System compliance standards, a quant. method was created for cannabis anal., and validated using Eurachem V.2 (2014) guidelines. Cannabinol, cannabidiol, cannabigerol, cannabichromene, cannabidiolic acid, cannabigerolic acid, Δ-9-tetrahydrocannabinol, and Δ-9-tetrahydrocannabinolic acid A were all analyzed by scheduled multiple reaction monitoring (MRM) via LC-MS/MS and isotope dilution In addition, aflatoxins B1, B2, G1, and G2 were also analyzed by scheduled MRM via LC-MS/MS and matrix matched calibration curves to achieve the reporting limits (≤2μg kg-1) set out by the European Pharmacopoeia. The LODs/LOQs were 0.50/1.7, 2.0/6.7, 0.59/2.0, and 0.53/1.8μg kg-1, for B1, B2, G1, and G2 resp. Thirty one terpenes were analyzed by selected reaction monitoring via GC-MS/MS and isotope dilution using β-myrcene-d6 as a surrogate. All quant. analyses can be accomplished using less than 1 g of material, with minimal solvent and consumable use, on low resolution instruments in less than 30 min of instrument time. Of important note is this method’s power of selectivity, working ranges, and lack of need for extraction consumables such as SPE or QuEChERS, thereby minimising anal. costs and time.

Analytica Chimica Acta published new progress about Cannabinoids Role: ANT (Analyte), ANST (Analytical Study). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Application In Synthesis of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Xiao-Tong published the artcileEffects of xingnaojing injection on adenosinergic transmission and orexin signaling in lateral hypothalamus of ethanol-induced coma rats, Synthetic Route of 124-76-5, the main research area is coma xingnaojing injection adenosinergic transmission orexin lateral hypothalamus.

Acute alc. exposure induces unconscious condition such as coma whose main phys. manifestation is the loss of righting reflex (LORR). Xingnaojing Injection (XNJI), which came from Chinese classic formula An Gong Niu Huang Pill, is widely used for consciousness disorders in China, such as coma. Although XNJI efficiently shortened the duration of LORR induced by acute ethanol, it remains unknown how XNJI acts on ethanol-induced coma (EIC). We performed experiments to examine the effects of XNJI on orexin and adenosine (AD) signaling in the lateral hypothalamic area (LHA) in EIC rats. Results showed that XNJI reduced the duration of LORR, which implied that XNJI promotes recovery form coma. Microdialysis data indicated that acute ethanol significantly increased AD release in the LHA but had no effect on orexin A levels. The qPCR results displayed a significant reduction in the Orexin-1 receptors (OX1R) expression with a concomitant increase in the A1 receptor (A1R) and equilibrative nucleoside transporter type 1 (ENT1) expression in EIC rats. In contrast, XNJI reduced the extracellular AD levels but orexin A levels remained unaffected. XNJI also counteracted the downregulation of the OX1R expression and upregulation of A1R and ENT1 expression caused by EIC. Based on these results, we suggest that XNJI promotes arousal by inhibiting adenosine neurotransmission via reducing AD level and the expression of A1R and ENT1.

BioMed Research International published new progress about Blumea balsamifera. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Synthetic Route of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Al-Wahaibi, Lamya H. Naser published the artcileComparative study on the essential oils of Artemisia judaica and A. herba-alba from Saudi Arabia, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Artemisia Aspergillus Syncephalastrum Bacillis Pseudomonas essential oils Saudi Arabia.

The volatile chem. constituents derived from two Asteraceae species (Artemisia judaica and A. herba-alba) were analyzed and compared for the first time using gas chromatog. techniques (GC-MS, GC-FID, Co-GC, LRI determination, database and literature searches) on two different stationary phase columns (polar and nonpolar). This anal. led to the identification of a total of 110 and 81 components from whole plant (stems, leaves and flowers) oils of A. judaica and A. herba-alba resp. The major classes of compounds in both plants included oxygenated monoterpenes, sesquiterpenes and hydrocarbons. The prominent components in the oil of A. judaica were β-eudesmol, hexadecanoic acid, spathulenol, eudesma-4 (15),7-dien-1-β-ol, carvacrol and thymol which account for 67.3% of the total essential oils composition (96.7%). While the main oil constituents from A. herba-alba were piperitone, (E)-ethylcinnamate, (Z)-ethylcinnamate, thymol, isophrone which account for 78.0% of the total oil composition (99.6%). Comparison showed similar composition in thymol and spathulenol while in others major constituents, have opposite values. To the best of our knowledge, both plant species (A. judaica and A. herba-alba) from Saudi Arabia were considered for the first time in this study. In addition, the oils of these plants were screened for their bio-activities and were found to possess significant anti-microbial activities.

Arabian Journal of Chemistry published new progress about Antimicrobial agents. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Delong published the artcileGuaiacol as a natural melanin biosynthesis inhibitor to control northern corn leaf blight, Application In Synthesis of 124-76-5, the main research area is guaiacol natural melanin essential oil corn leaf blight; DHN melanin biosynthesis inhibitor; guaiacol; northern corn leaf blight; plant essential oil compounds.

BACKGROUND : The natural 1,8-dihydroxynaphthalene (DHN) melanin biosynthesis inhibitors (MBIs) are one of the promising approaches to the integrated management of plant diseases but have received scarce attention until now. Herein, to explore the natural DHN MBIs used in the control of northern corn leaf blight (NCLB), a library of 53 essential oil compounds was used to screen the MBIs against Exserohilum turcicum, the causal pathogen of NCLB, using tricyclazole as a reference compound RESULTS : The results of morphol. change in the colony, thermogravimetric anal., UV-visible spectroscopy, and transmission electron microscopy confirmed that guaiacol could effectively inhibit the melanin production at 50 μg/mL under in vitro conditions. The in vitro bioassay results indicated that this inhibition effect was concentration-dependent and the min. inhibition concentration of guaiacol was 50 μg/mL. The in vivo exptl. results demonstrated that guaiacol significantly inhibited appressorium formation and penetration on corn leaf sheaths at the concentration of 500 μg/mL. The pot experiment results revealed that there were no differences between guaiacol (500 μg/mL) and tricyclazole (100 μg/mL) in control efficacy. The enzymic assay suggested that guaiacol might exert the activity through inhibiting DHN polymerization to form melanins, which was distinct from tricyclazole. CONCLUSIONS : Taken together, this study screened out guaiacol as a natural MBI from 53 essential oil compounds and verified its effectiveness in the control of NCLB at 500 μg/mL. Above all, this research opened an avenue for exploring natural DHN MBIs in the integrated management of plant diseases. 2022 Society of Chem. Industry.

Pest Management Science published new progress about Color. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Application In Synthesis of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts