Category: 1195-59-1

In 2022,Yeung, Jason; Becker, Matthias; Stephan, Douglas W. published an article in Dalton Transactions. The title of the article was 《Towards macrocyclic frustrated Lewis pairs》.Safety of 2,6-Pyridinedimethanol The author mentioned the following in the article:

Macrocycles with and without B-N bonds were prepared from reaction of C6F5BH2·SMe2 or MesBH2 with the 2,6-pyridinedimethanol derivatives Both classes of macrocycle reacted with B(C6F5)3 but were unreactive to small mols. These observations provide insights for the subsequent design of macrocyclic FLPs for multi-electron reactions. After reading the article, we found that the author used 2,6-Pyridinedimethanol(cas: 1195-59-1Safety of 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Safety of 2,6-Pyridinedimethanol

Referemce:
Alcohol – Wikipedia,
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Category: alcohols-buliding-blocksIn 2019 ,《O-H and (CO)N-H bond weakening by coordination to Fe(II)》 appeared in Dalton Transactions. The author of the article were Resa, Sandra; Millan, Alba; Fuentes, Noelia; Crovetto, Luis; Luisa Marcos, M.; Lezama, Luis; Choquesillo-Lazarte, Duane; Blanco, Victor; Campana, Araceli G.; Cardenas, Diego J.; Cuerva, Juan M.. The article conveys some information:

New N,N’-dimethyl-N,N’-bis(2-pyridylmethyl)-ethane-1,2-diamine derivatives bearing covalently linked OH and (CO)NH groups were synthesized. The coordination of those pendant hydroxyl/amide groups to a Fe(II) metal center is demonstrated both in solution, even in the presence of chloride as the counterion, and in solid state, by x-ray diffraction crystal structures. As a result of this coordination, the exptl. bond dissociation free energies (BDFE) of O-H and (CO)N-H bonds are remarkably diminished down to 76.0 and 80.5 kcal mol-1, resp., which is also in agreement with DFT-based theor. calculations These BDFE values are in the range of commonly used hydrogen-atom donor reagents. The strategy presented here allows an unequivocal evaluation of the influence of metal coordination in X-H bond weakening in organic solvents which could be easily extended to other metal centers. The experimental process involved the reaction of 2,6-Pyridinedimethanol(cas: 1195-59-1Category: alcohols-buliding-blocks)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.Category: alcohols-buliding-blocks

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Alcohol – Wikipedia,
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《Effect of the distant substituent on the slow magnetic relaxation of the mononuclear Co(II) complex with pincer-type ligands》 was published in Dalton Transactions in 2020. These research results belong to Rajnak, Cyril; Titis, Jan; Moncol’, Jan; Boca, Roman. Name: 2,6-Pyridinedimethanol The article mentions the following:

A hexacoordinated complex [Co(pydm)2](mdnbz)2 from the family of pincer complexes was prepared and structurally characterized. The complex behaves as an S = 3/2 spin system with a considerable zero-field splitting parameter D/hc ~+50 cm-1. The a.c. susceptibility measurements show a slow magnetic relaxation with three relaxation channels: at the low-frequency (LF), intermediate-frequency (IF) and high-frequency (HF) domains. At T = 2.0 K and an external field BDC = 0.25 T, the relaxation times of the individual modes are τ(LF) = 282 ms, τ(IF) = 3.1 ms, and τ(HF) = 0.16 ms, and the mole fractions of the slowly relaxing species are x(LF) = 0.19, x(IF) = 0.45, and x(HF) = 0.37. A comparison with the analogous complex [Co(pydm)2](dnbz)2 possessing a demethylated counteranion and identical metal cation shows that even small modifications in the composition of SIMs are no longer underestimated for the slow magnetic relaxation. In addition to this study using 2,6-Pyridinedimethanol, there are many other studies that have used 2,6-Pyridinedimethanol(cas: 1195-59-1Name: 2,6-Pyridinedimethanol) was used in this study.

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Name: 2,6-Pyridinedimethanol

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Quality Control of 2,6-PyridinedimethanolIn 2020 ,《Manganese Complex of a Rigidified 15-Membered Macrocycle: A Comprehensive Study》 appeared in Inorganic Chemistry. The author of the article were Pota, Kristof; Molnar, Eniko; Kalman, Ferenc Krisztian; Freire, David M.; Tircso, Gyula; Green, Kayla N.. The article conveys some information:

Owing to the increasing importance of manganese(II) complexes in the field of magnetic resonance imaging (MRI), large efforts were devoted to find an appropriate ligand for Mn(II) ion encapsulation by providing balance between the seemingly contradictory requirements (i.e., thermodn. stability and kinetic inertness vs. low ligand denticity enabling water mol.(s) to be coordinated in its metal center). Among these ligands, a large number of pyridine or pyridol based open-chain and macrocyclic chelators were studied so far. As a next step in the development of these chelators, 15-pyN3O2Ph and its transition metal complexes were synthesized and characterized using established methods. The 15-pyN3O2Ph ligand incorporates both pyridine and ortho-phenylene units to decrease ligand flexibility. The thermodn. properties, protonation and stability constants, were determined using pH-potentiometry; the solid-state structures of two protonation states of the free ligand and its manganese complex were obtained by single crystal x-ray diffractometry. The results show a seven-coordinate metal center with two water mols. in the first coordination sphere. The longitudinal relaxivity of [Mn(15-pyN3O2Ph)]2+ is 5.16 mM-1s-1 at 0.49 T (298 K). Furthermore, the r2p value of 11.72 mM-1s-1 (0.49 T), which is doubled at 1.41 T field, suggests that design of this Mn(II) complex does achieve some characteristics required for contrast imaging. In addition, 17O NMR measurements were performed to access the microscopic parameters governing this key feature (e.g., water exchange rate). Finally, manganese complexes of ligands with analogous polyaza macrocyclic scaffold were studied as low mol. weight Mn(CAT) mimics. Here, the authors report the H2O2 disproportionation study of [Mn(15-pyN3O2Ph)]2+ to demonstrate the versatility of this ligand scaffold as well. The highly rigidified 15-pyN3O2Ph ligand and its Mn(II) complex was synthesized and characterized using pH potentiometry, 1H relaxometry, and x-ray diffractometry. As a result of the aromatic structural moieties, the longitudinal and transverse relaxivities turned out to be outstanding (5.16 and 11.72 mM-1s-1) compared to other lower mol. weight MRI contrast agents. Also, this seven-coordinate complex can act as an effective H2O2 disproportionation catalyst, similar to MnCAT mimics. The experimental part of the paper was very detailed, including the reaction process of 2,6-Pyridinedimethanol(cas: 1195-59-1Quality Control of 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.Quality Control of 2,6-Pyridinedimethanol

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Alcohol – Wikipedia,
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In 2018,Brethome, Flavien M.; Williams, Neil J.; Seipp, Charles A.; Kidder, Michelle K.; Custelcean, Radu published 《Direct air capture of CO2 via aqueous-phase absorption and crystalline-phase release using concentrated solar power》.Nature Energy published the findings.Recommanded Product: 2,6-Pyridinedimethanol The information in the text is summarized as follows:

Using neg. emissions technologies for the net removal of greenhouse gases from the atm. could provide a pathway to limit global temperature rises. Direct air capture of carbon dioxide offers the prospect of permanently lowering the atm. CO2 concentration, providing that economical and energy-efficient technologies can be developed and deployed on a large scale. Here, we report an approach to direct air capture, at the laboratory scale, using mostly off-the-shelf materials and equipment. First, CO2 absorption is achieved with readily available and environmentally friendly aqueous amino acid solutions (glycine and sarcosine) using a household humidifier. The CO2-loaded solutions are then reacted with a simple guanidine compound, which crystallizes as a very insoluble carbonate salt and regenerates the amino acid sorbent. Finally, effective CO2 release and near-quant. regeneration of the guanidine compound are achieved by relatively mild heating of the carbonate crystals using concentrated solar power. In the experiment, the researchers used many compounds, for example, 2,6-Pyridinedimethanol(cas: 1195-59-1Recommanded Product: 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Recommanded Product: 2,6-Pyridinedimethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2018,Inorganic Chemistry included an article by Shimoda, Tomoe; Morishima, Takeshi; Kodama, Koichi; Hirose, Takuji; Polyansky, Dmitry E.; Manbeck, Gerald F.; Muckerman, James T.; Fujita, Etsuko. Recommanded Product: 2,6-Pyridinedimethanol. The article was titled 《Photocatalytic CO2 Reduction by Trigonal-Bipyramidal Cobalt(II) Polypyridyl Complexes: The Nature of Cobalt(I) and Cobalt(0) Complexes upon Their Reactions with CO2, CO, or Proton》. The information in the text is summarized as follows:

The cobalt complexes CoIIL1(PF6)2 (1; L1 = 2,6-bis[2-(2,2′-bipyridin-6′-yl)ethyl]pyridine) and CoIIL2(PF6)2 (2; L2 = 2,6-bis[2-(4-methoxy-2,2′-bipyridin-6′-yl)ethyl]pyridine) were synthesized and used for photocatalytic CO2 reduction in acetonitrile. X-ray structures of complexes 1 and 2 reveal distorted trigonal-bipyramidal geometries with all nitrogen atoms of the ligand coordinated to the Co(II) center, in contrast to the common six-coordinate cobalt complexes with pentadentate polypyridine ligands, where a monodentate solvent completes the coordination sphere. Under electrochem. conditions, the catalytic current for CO2 reduction was observed near the Co(I/0) redox couple for both complexes 1 and 2 at E1/2 = -1.77 and -1.85 V vs. Ag/AgNO3 (or -1.86 and -1.94 V vs Fc+/0), resp. Under photochem. conditions with 2 as the catalyst, [Ru(bpy)3]2+ as a photosensitizer, tri-p-tolylamine (TTA) as a reversible quencher, and triethylamine (TEA) as a sacrificial electron donor, CO and H2 were produced under visible-light irradiation, despite the endergonic reduction of Co(I) to Co(0) by the photogenerated [Ru(bpy)3]+. However, bulk electrolysis in a wet CH3CN solution resulted in the generation of formate as the major product, indicating the facile production of Co(0) and [Co-H]n+ (n = 1 and 0) under electrochem. conditions. The one-electron-reduced complex 2 reacts with CO to produce [Co0L2(CO)] with νCO = 1894 cm-1 together with [CoIIL2]2+ through a disproportionation reaction in acetonitrile, based on the spectroscopic and electrochem. data. Electrochem. and time-resolved UV-vis spectroscopy indicate a slow CO binding rate with the [CoIL2]+ species, consistent with d. functional theory calculations with CoL1 complexes, which predict a large structural change from trigonal-bipyramidal to distorted tetragonal geometry. The reduction of CO2 is much slower than the photochem. formation of [Ru(bpy)3]+ because of the large structural changes, spin flipping in the cobalt catalytic intermediates, and an uphill reaction for the reduction to Co(0) by the photoproduced [Ru(bpy)3]+. In the experimental materials used by the author, we found 2,6-Pyridinedimethanol(cas: 1195-59-1Recommanded Product: 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Recommanded Product: 2,6-Pyridinedimethanol

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《Magneto-structural studies of an unusual [MnIIIMnIIGdIII(OR)4]4- partial cubane from 2,2′-bis-p-tBu-calix[4]arene》 was written by Coletta, Marco; Sanz, Sergio; Cutler, Daniel J.; Teat, Simon J.; Gagnon, Kevin J.; Singh, Mukesh K.; Brechin, Euan K.; Dalgarno, Scott J.. Recommanded Product: 1195-59-1 And the article was included in Dalton Transactions in 2020. The article conveys some information:

Reaction of 2,2′-bis-p-tBu-calix[4]arene (H8L) with MnCl2·4H2O, GdCl3·6H2O and 2,6-pyridinedimethanol (H2pdm) affords [MnIIIMnIIGdIII(H3L)(pdmH)(pdm)(MeOH)2(dmf)]·3MeCN·dmf (3·3MeCN·dmf) upon vapor diffusion of MeCN into the basic dmf/MeOH mother liquor. 3 Crystallizes in the tetragonal space group P41212 with the asym. unit comprising the entire cluster. The highly unusual core contains a triangular arrangement of MnIIIMnIIGdIII ions housed within a [MnIIIMnIIGdIII(OR)4]4- partial cubane. Magnetic susceptibility and magnetization data reveal best fit parameters JMn(II)-Mn(III) = +0.415 cm-1, JMn(III)-Gd(III) = +0.221 cm-1, JMn(II)-Gd(III) = -0.258 cm-1 and DMn(III) = -4.139 cm-1. Theor. derived magnetic exchange interactions, anisotropy parameters, and magneto-structural correlations for 3 are in excellent agreement with the exptl. data. In the experiment, the researchers used 2,6-Pyridinedimethanol(cas: 1195-59-1Recommanded Product: 1195-59-1)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Recommanded Product: 1195-59-1

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Application In Synthesis of 2,6-PyridinedimethanolIn 2021 ,《A Universal Chemical Method for Rational Design of Protein-Based Nanoreactors》 appeared in ChemBioChem. The author of the article were Reddy, Mullapudi Mohan; Bathla, Punita; Sandanaraj, Britto S.. The article conveys some information:

Self-assembly of a monomeric protease to form a multi-subunit protein complex “”proteasome”” enables targeted protein degradation in living cells. Naturally occurring proteasomes serve as an inspiration and blueprint for the design of artificial protein-based nanoreactors. Here we disclose a general chem. strategy for the design of proteasome-like nanoreactors. Micelle-assisted protein labeling (MAPLab) technol. along with the N-terminal bioconjugation strategy is utilized for the synthesis of a well-defined monodisperse self-assembling semi-synthetic protease. The designed protein is programmed to self-assemble into a proteasome-like nanostructure which preserves the functional properties of native protease. In the experiment, the researchers used 2,6-Pyridinedimethanol(cas: 1195-59-1Application In Synthesis of 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.Application In Synthesis of 2,6-Pyridinedimethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Chemistry of Materials included an article by Das, Gobinda; Nagaraja, Sharadhi; Sridurai, Vimala; Shinde, Digambar B.; Addicoat, Matthew; Prakasam, Thirumurugan; Gandara, Felipe; Ravaux, Florent; Sharma, Sudhir Kumar; Nair, Geetha G.; Lai, Zhiping; Jagannathan, Ramesh; Olson, Mark A.; Trabolsi, Ali. Application In Synthesis of 2,6-Pyridinedimethanol. The article was titled 《Redox-Triggered Buoyancy and Size Modulation of a Dynamic Covalent Gel》. The information in the text is summarized as follows:

The development of stimuli-responsive materials capable of transducing external stimuli into mech. and phys. changes has always been an intriguing challenge and an inspiration for scientists. Several stimuli-responsive gels have been developed and applied to biomimetic actuators or artificial muscles. Redox-active actuators in which the mech. motion is driven chem. or electrochem. have attracted much interest, and their actuation mechanism is based on the change in electrostatic repulsion and the loss or gain of counterions to balance newly formed charges. Actuation can also be promoted by changing the hydration state of the material, leading to the release/adsorption of water mols. from the network, inducing a direct shrinking/swelling of the material, resp. A cationic crystalline dynamic covalent gel was obtained via the formation of imine bonds between 2,6-diformyl pyridine and triamino guanidinium chloride. The gel exhibits a reversible contraction/expansion behavior in response to base (oxidation, -H+, -e-) and acid (reduction +H+, +e-), resp. The oxidation induces a color change and contraction of the gel with a concomitant increase in its strength. As synthesized, the cationic gel is denser than water and sinks when placed in water. Upon oxidation, the radical cationic gel expels water mols., rendering it less dense than water and the gel is propelled to the surface without any loss of its structural integrity. These results demonstrate that a careful choice of amine and aldehyde linkers can give rise to imine-linked materials capable of tolerating and resisting extreme acidic and basic conditions while performing work. In the experiment, the researchers used many compounds, for example, 2,6-Pyridinedimethanol(cas: 1195-59-1Application In Synthesis of 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Application In Synthesis of 2,6-Pyridinedimethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Dalton Transactions included an article by Wang, Hui-Sheng; Long, Qiao-Qiao; Hu, Zhao-Bo; Yue, Lin; Yang, Feng-Jun; Yin, Cheng-Ling; Pan, Zhi-Quan; Zhang, Yi-Quan; Song, You. Category: alcohols-buliding-blocks. The article was titled 《Synthesis, crystal structures and magnetic properties of a series of chair-like heterometallic [Fe4Ln2] (Ln = GdIII, DyIII, HoIII, and ErIII) complexes with mixed organic ligands》. The information in the text is summarized as follows:

Four chair-like hexanuclear Fe-Ln complexes containing mixed organic ligands, namely, [Fe4Ln2{(py)2CO2}4(pdm)2(NO3)2(H2O)2Cl4]·xCH3CN·yH2O (Ln = GdIII (1, x = 1, y = 0), DyIII (2, x = 1, y = 1), HoIII (3, x = 0, y = 2), and ErIII (4, x = 1, y = 3); (py)2CO2H2 = the gem-diol form of di-2-pyridyl ketone and pdmH2 = 2,6-pyridinedimethanol) were obtained by employing di-2-pyridyl ketone and 2,6-pyridinedimethanol reacting with FeCl3 and Ln(NO3)3 in MeCN. The structures of 1-4 are similar to each other except for the number of lattice solvent mols. Four FeIII and two LnIII in these complexes comprise a chair-like core with the body constructed by four FeIII ions and the end constructed by two LnIII ions. Among the four compounds, 2 shows field-induced single mol. magnet behavior as revealed by a.c. magnetic susceptibility studies, with the effective energy barrier and the pre-exponential factor of 22.07 K and 8.44 × 10-7 s, resp. Ab initio calculations indicated that, among 2_Dy, 3_Ho and 4_Er fragments, the energy gap between the lowest two spin-orbit states for 2_Dy is the largest, while the tunneling gap for 2 is the smallest. These might be the reasons for complex 2 exhibiting SMM behavior. Addnl., the orientations of the magnetic anisotropy of DyIII in 2 were obtained by electrostatic calculations and ab initio calculations, both indicating that the directions of the main magnetic axis of Dy1 ions are almost aligned along Dy1-O5 (O5 from the pdm2- ligand). In the experimental materials used by the author, we found 2,6-Pyridinedimethanol(cas: 1195-59-1Category: alcohols-buliding-blocks)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts