Category: 1195-59-1

Vezse, Panna; Benda, Bianka; Fekete, Andras; Golcs, Adam; Toth, Tunde; Huszthy, Peter published an article in 2022. The article was titled 《Covalently Immobilizable Tris(Pyridino)-Crown Ether for Separation of Amines Based on Their Degree of Substitution》, and you may find the article in Molecules.Application of 1195-59-1 The information in the text is summarized as follows:

A great number of biol. active compounds contain at least one amine function. Appropriate selectivity can only be accomplished in a few cases upon the substitution of these groups, thus functionalization of amines generally results in a mixture of them. The separation of these derivatives with very similar characteristics can only be performed on a preparative scale or by applying pre-optimized HPLC methods. A tris(pyridino)-crown ether was designed and synthesized for overcoming these limitations at a mol. level. It is demonstrated, that this selector mol. is able to distinguish protonated primary, secondary and tertiary amines by the formation of reversible complexes with different stabilities. This degree of substitution-specific mol. recognition of amines opens the door to develop separation processes primarily focusing on the purification of biol. active compounds in a nanomolar scale. The experimental process involved the reaction of 2,6-Pyridinedimethanol(cas: 1195-59-1Application of 1195-59-1)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Application of 1195-59-1

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In 2022,Sarkar, Nabin; Sahoo, Rajata Kumar; Patro, A. Ganesh; Nembenna, Sharanappa published an article in Polyhedron. The title of the article was 《Aluminum-catalyzed selective hydroboration of carbonyls and dehydrocoupling of alcohols, phenols, amines, thiol, selenol, silanols with HBpin》.HPLC of Formula: 1195-59-1 The author mentioned the following in the article:

A popular N,N’-chelated NacNac analog, i.e., conjugated bis-guanidinate (CBG) stabilized aluminum dihydride LAlH2 [1; L = ArNC(ArNH):NC:(NHAr)NAr, where Ar = 2,6-Et2-C6H3], demonstrates excellent catalytic hydroboration of a wide array of carbonyls with pinacolborane (HBpin) under neat conditions with good tolerance of reducible functional groups such as alkyl, alkene, halide, nitrile, nitro, ester, amide, and heteroaryl. In addition, we investigated complex 1 catalyzed cross-dehydrocoupling (CDC) of alcs., phenols, amines, thiol, selenol, and silanols with HBpin under mild reaction conditions. Furthermore, several control experiments have been performed to understand the mechanisms in hydroboration and CDC reactions. All corresponding catalytic intermediates have been identified and characterized by 1H and 13C{1H} NMR spectroscopic methods. In contrast to several reports on metal-catalyzed hydroboration of carbonyls, this is the second report for the mol. aluminum catalyzed CDC of organic substrates with HBpin. In the part of experimental materials, we found many familiar compounds, such as 2,6-Pyridinedimethanol(cas: 1195-59-1HPLC of Formula: 1195-59-1)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.HPLC of Formula: 1195-59-1

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Related Products of 1195-59-1In 2021 ,《A selective and sensitive near-infrared fluorescent probe for real-time detection of Cu(I)》 was published in RSC Advances. The article was written by Liu, Yiqing; Kang, Ting; He, Qian; Hu, Yuefu; Zuo, Zeping; Cao, Zhihua; Ke, Bowen; Zhang, Weiyi; Qi, Qingrong. The article contains the following contents:

The disruption of copper homeostasis (Cu+/Cu2+) may cause neurodegenerative disorders. Thus, the need for understanding the role of Cu+ in physiol. and pathol. processes prompted the development of improved methods of Cu+ anal. Herein, a new near-IR (NIR) fluorescent turn-on probe (NPCu) for the detection of Cu+ was developed based on a Cu+-mediated benzylic ether bond cleavage mechanism. The probe showed high selectivity and sensitivity toward Cu+, and was successfully applied for bioimaging of Cu+ in living cells. In the experiment, the researchers used many compounds, for example, 2,6-Pyridinedimethanol(cas: 1195-59-1Related Products of 1195-59-1)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Related Products of 1195-59-1

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《CaCl2-Promoted Dehydroxytrifluoromethylselenolation of Alcohols with [Me4N][SeCF3]》 was published in Organic Letters in 2020. These research results belong to Wu, Shuai; Jiang, Tian-Hao; Zhang, Cheng-Pan. Formula: C7H9NO2 The article mentions the following:

A direct trifluoromethylselenolation of alcs. with the readily accessible [Me4N][SeCF3] salt has been reported. The reaction is significantly promoted by CaCl2 and proceeds smoothly through unprecedented carbonoselenoate intermediates to form the corresponding alkyl trifluoromethyl selenoethers in good yields. This protocol is also applicable to the late-stage dehydroxytrifluoromethylselenolation of complex alcs. owing to its mildness, good compatibility, high efficiency, and broad functional group tolerance. The experimental part of the paper was very detailed, including the reaction process of 2,6-Pyridinedimethanol(cas: 1195-59-1Formula: C7H9NO2)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Formula: C7H9NO2

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《A novel sustainable metal organic framework as the ultimate aqueous phase sensor for natural hazards: detection of nitrobenzene and F- at the ppb level and rapid and selective adsorption of methylene blue》 was written by I., Mantasha; Shahid, M.; Saleh, Hatem A. M.; Qasem, Khalil M. A.; Ahmad, Musheer. Category: alcohols-buliding-blocks And the article was included in CrystEngComm in 2020. The article conveys some information:

Herein, a new cationic Cu(II)-based porous and water stable metal organic framework (MOF), [{Cu(bipy)1.5(H2pdm)}βoxO3βox]n (Cu-MOF-1) is designed using pyridine-2,6-dimethanol (H2pdm) and 4,4′-bipyridine (bipy) through slow evaporation process. The MOF is characterized by FTIR, PXRD, TGA, magnetic and single crystal XRD anal. The structural unit of Cu-MOF-1 consists of two Cu(II) ions bridged by bipy and supported by the H2pdm. This material exhibits excellent sensing ability for nitrobenzene (NB) and fluoride ion (F-) in 100% aqueous medium with ultra-low limit of detection (LOD) i.e., 0.093 and 1.203 ppb for NB and F-, resp. The detection of NACs is governed by PET and FRET mechanism while vapor pressure plays major role for NB detection showing highest fluorescent quenching of 96.4%. Moreover, the MOF revealed high water stability, significant recyclability and microporosity. The MOF was also employed for adsorption and separation of methylene blue from the mixture of three dyes (methylene blue, rhodamine-B and methyl orange). At equilibrium, the removal percentage of Cu-MOF-1 for MB is 98.23% and the mechanism of dye adsorption is also explored. Thus, the present MOF comes out as a sustainable multifunctional material for aqueous phase sensing of hazardous nitrobenzene and fluoride ions, as well as an excellent dye adsorbent. In addition to this study using 2,6-Pyridinedimethanol, there are many other studies that have used 2,6-Pyridinedimethanol(cas: 1195-59-1Category: alcohols-buliding-blocks) was used in this study.

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Category: alcohols-buliding-blocks

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The author of 《New Set of Multicomponent Crystals as Efficient Heterogeneous Catalysts for the Synthesis of Cyclic Carbonatesã€?were Kundu, Arunangshu; Saikia, Swagata; Majumder, Manoj; Sengupta, Oindrila; Bhattacharya, Biswajit; De, Gobinda Chandra; Ghosh, Sushobhan. And the article was published in ACS Omega in 2019. Product Details of 1195-59-1 The author mentioned the following in the article:

Three new multicomponent crystals of Zn(II), Mn(II) and Co(II) resp. were synthesized by the reaction of 2,6-bis(hydroxymethyl)pyridine, the resp. metal salts and sodium benzoate in 1:1:2 ratio. One component of these multicomponent crystals is the dicationic 2,6-bis(hydroxymethyl)pyridine metal complex and the other component is the dianionic tetrabenzoate complex of the same metal. The complexes were fully characterized by single crystal X-ray structure determination The X-ray structure of these compounds reveal the formation of 1D supramol. chain parallel to the crystallog. b axis via H-bonding interaction between the dicationic and the dianionic parts of the resp. compound The Mn(II) and Co(II) complexes show antiferromagnetic coupling between the two associated metal centers via H-bonding interaction pathway. All the three compounds were tested as heterogeneous catalystic systems for the successful conversion of epoxides to cyclic carbonates in solvent free condition under approx. 10 bar of pressure of CO2 and temperature ranging between 60 – 80 °C along with tetra-Bu ammonium bromide acting as cocatalyst. All the three compounds were found to have turnover number more than 1000 for the resp. epoxides except for the conversion of cyclohexene oxide to cyclohexene carbonate. In the experiment, the researchers used 2,6-Pyridinedimethanol(cas: 1195-59-1Product Details of 1195-59-1)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Product Details of 1195-59-1

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《Visible Light-Induced α-C(sp3)-H Acetalization of Saturated Heterocycles Catalyzed by a Dimeric Gold Complexã€?was published in Organic Letters in 2020. These research results belong to Si, Xiaojia; Zhang, Lumin; Wu, Zuozuo; Rudolph, Matthias; Asiri, Abdullah M.; Hashmi, A. Stephen K.. Formula: C7H9NO2 The article mentions the following:

Saturated heterocyclic acetals are useful fragments in organic synthesis and other fields. Herein, C(sp3)-H dehydrogenative cross-couplings of ethers, tetrahydrothiophene, and N-Boc-pyrrolidine were achieved under visible light irradiation by using 4-iodoanisole and an in situ-formed gold complex. The broad functional group compatibility and substrate scope indicate that our strategy is a promising way to synthesize acetal analogs. The method was successfully applied in late-stage modifications of bioactive mols. Gram scale syntheses and mechanistic studies are also presented. In the part of experimental materials, we found many familiar compounds, such as 2,6-Pyridinedimethanol(cas: 1195-59-1Formula: C7H9NO2)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Formula: C7H9NO2

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《Solvent-Free N-Alkylation and Dehydrogenative Coupling Catalyzed by a Highly Active Pincer-Nickel Complexã€?was written by Arora, Vinay; Dutta, Moumita; Das, Kanu; Das, Babulal; Srivastava, Hemant Kumar; Kumar, Akshai. Application of 1195-59-1 And the article was included in Organometallics in 2020. The article conveys some information:

The synthesis and characterization of a pincer-Ni complex (iPr2NNN)NiCl2(MeCN) is reported here. The authors demonstrated the utility of this pincer-Ni complex (0.02 mol % and 0.002 mol %) for the catalytic N-alkylation of amines using various alcs. Under solvent-free conditions, while the highest yield (âˆ?0%) was obtained for alkylation of 2-amino pyridine with naphthyl-1-methanol, excellent turnovers (34000 TONs) was observed for alkylation of 2-amino pyridine with 4-methoxy benzyl alc. To demonstrate the synthetic utility of these systems, high yield reactions (up to 98%) were probed for representative substrates with a higher loading of the pincer-Ni catalyst (4 mol %). DFT studies indicate that while β-hydride elimination is the RDS for alc. dehydrogenation, the N-alkylated product can be formed either via hydrogenation with a rate-determining σ-bond metathesis or by alcoholysis that has imine insertion as RDS. All the corresponding resting states were observed by HRMS(ESI) anal. The labeling experiments are also complementary to DFT studies and show evidence for the involvement of benzylic C-H bond in RDS with a kCHH/kCHD of âˆ?.5. This method was applied to accomplish efficient (2000 TONS) dehydrogenative coupling leading to various benzimidazoles. After reading the article, we found that the author used 2,6-Pyridinedimethanol(cas: 1195-59-1Application of 1195-59-1)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Application of 1195-59-1

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In 2018,Dey, Subal; Ahmed, Estak Md; Dey, Abhishek published 《Activation of Co(I) State in a Cobalt-Dithiolato Catalyst for Selective and Efficient CO2 Reduction to CO》.Inorganic Chemistry published the findings.Name: 2,6-Pyridinedimethanol The information in the text is summarized as follows:

Reduction of CO2 holds the key to solving 2 major challenges taunting the society-clean energy and clean environment. There is an urgent need for the development of efficient nonnoble metal-based catalysts that can reduce CO2 selectively and efficiently. Unfortunately, activation and reduction of CO2 can only be achieved by highly reduced metal centers jeopardizing the energy efficiency of the process. A CO dehydrogenase inspired Co complex bearing a dithiolato ligand can reduce CO2, in wet MeCN, to CO with ∼95% selectivity over a wide potential range and 1559 s-1 rate with a remarkably low overpotential of 70 mV. Unlike most of the transition metal-based systems that require reduction of the metal to its formal zerovalent state for CO2 reduction, this catalyst can reduce CO2 in its formal +1 state making it substantially more energy efficient than any system known to show similar reactivity. While covalent donation from 1 thiolate increases electron d. at the Co(I) center enabling it to activate CO2, protonation of the bound thiolate, in the presence of H2O as a proton source, plays a crucial role in lowering overpotential (thermodn.) and ensuring facile proton transfer to the bound CO2 ensuring facile (kinetics) reactivity. A very covalent Co(III)-C bond in a Co(III)-COOH intermediate is at the heart of selective protonation of the O atoms to result in CO as the exclusive product of the reduction In the experiment, the researchers used many compounds, for example, 2,6-Pyridinedimethanol(cas: 1195-59-1Name: 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Name: 2,6-Pyridinedimethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,ACS Catalysis included an article by Bains, Amreen K.; Kundu, Abhishek; Yadav, Sudha; Adhikari, Debashis. Computed Properties of C7H9NO2. The article was titled 《Borrowing Hydrogen-Mediated N-Alkylation Reactions by a Well-Defined Homogeneous Nickel Catalyst》. The information in the text is summarized as follows:

We report herein a well-defined and bench-stable azo-phenolate ligand-coordinated nickel catalyst which can efficiently execute N-alkylation of a variety of anilines by alc. We demonstrate that the redox-active azo ligand can store hydrogen generated during alc. oxidation and redelivers the same to an in-situ-generated imine bond to result in N-alkylation of amines. The reaction has wide scope, and a large array of alcs. can directly couple to a variety of anilines. Mechanistic studies including deuterium labeling to the substrate establishes the borrowing hydrogen method from alcs. and pinpoints the crucial role of the redox-active azo moiety present on the ligand backbone. Isolation of the ketyl intermediate in its trapped form with a radical quencher and higher kH/kD for the alc. oxidation step suggest altogether a hydrogen-atom transfer (HAT) to the reduced azo backbone to pave alc. oxidation as opposed to the conventional metal-ligand bifunctional mechanism. This example clearly demonstrates that an inexpensive base metal catalyst can accomplish an important coupling reaction with the help of a redox-active ligand backbone. The results came from multiple reactions, including the reaction of 2,6-Pyridinedimethanol(cas: 1195-59-1Computed Properties of C7H9NO2)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Computed Properties of C7H9NO2

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