Category: 119-47-1

Xu, Min;Wu, Ruixia;Liang, Yuan;Fu, Ke;Zhou, You;Li, Xiaoli;Wu, Lei;Wang, Zhang published 《Protective effect and mechanism of Qishiwei Zhenzhu pills on cerebral ischemia-reperfusion injury via blood-brain barrier and metabonomics》. The research results were published in《Biomedicine & Pharmacotherapy》 in 2020.Quality Control of 2,2-Methylenebis(6-tert-butyl-p-cresol) The article conveys some information:

Stroke is an acute cerebrovascular disease caused by the sudden rupture of cerebral blood vessels or vascular obstruction from brain tissue damage or dysfunction, thereby preventing blood flow into the brain. Cerebral ischemia-reperfusion injury (CI/RI), a common syndrome of ischemic stroke, is a complex pathol. process whose physiol. mechanism is still unclear. Qishiwei Zhenzhu pills (QSW), a famous Tibetan medicine preparation, has the effect of tranquilizing by heavy settling, dredging channels and activating collaterals, harmonizing Qi and blood, restoring consciousness, and inducing resuscitation. Here, we investigated the protective effect of QSW on CI/RI in rats and its potential mechanism. First, the volatile and liposol. components in QSW were determined using gas chromatog.-mass spectrometry (GC-MS). After 24 h of CI/RI, the neuroprotective effect was determined by evaluating the neurol. function, cerebral infarction, histopathol., and blood-brain barrier (BBB) function. Immunofluorescence, real-time quant. PCR (RT-qPCR), and western blot (WB) were used to detect the expression of matrix metalloproteinase 9 (MMP-9), claudin-5, and occludin. Finally, GC-MS metabonomics was used to identify different metabolites and analyze metabolic pathways. The results showed that 88 volatile components and 63 liposol. components were detected in QSW. Following the exptl. stroke operation, it was observed that rats administered QSW pretreatment had improved neurol. function, reduced infarct volume (P < 0.01), increased Nissl bodies (P < 0.05), improved histopathol., and reduced BBB disruption. Immunofluorescence, RT-qPCR, and WB results showed that MMP-9 level in the brain tissue of the QSW pretreatment group had a decreasing trend and the expression of claudin-5 and occludin had a tendency to increase. Eleven metabolites related to lipid metabolism, fatty acid metabolism, and energy metabolism, were identified via GC-MS metabonomics. Our study shows that QSW preconditioning has a neuroprotective effect on CI/RI; however, its mechanism requires further study.2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) were involved in the experimental procedure.

Quality Control of 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Recommanded Product: 2,2-Methylenebis(6-tert-butyl-p-cresol)In 2022, Dai, Chenbo;Yang, Libin;Wang, Jun;Li, Dezhen;Zhang, Yalei;Zhou, Xuefei published 《Enhancing anaerobic digestion of pharmaceutical industries wastewater with the composite addition of zero valent iron (ZVI) and granular activated carbon (GAC)》. 《Bioresource Technology》published the findings. The article contains the following contents:

Anaerobic digestion of pharmaceutical wastewater is challenged by its contained toxic compounds which limits the stability and efficiency of methane production and organic degradation In this study, zero valent iron (ZVI) and granular activated carbon (GAC) were added with different strategies to improve anaerobic digestion of pharmaceutical wastewater. The results confirmed synergy effects of ZVI + GAC for both COD removal (increased by 13.4%) and methane production (increased by 11.0%). Furthermore, ZVI + GAC improved the removal of pharmaceutical intermediates, in particular, the residues (%) of dehydroepiandrosterone (DHEA) and 2,2′-methylenebis(6-tert-butyl-4-methylphenol) were only 30.48 ± 6.53 and 39.92 ± 4.50, and effectively reduced biotoxicity. The promoted results were attributed to the establishment of direct interspecies electron transfer (DIET). Microbial community anal. revealed that ZVI + GAC decreased species evenness and richness in bacterial whereas increased in archaeal. The relative abundance of acetotrophic methanogens decreased but hydrogenotrophic and methylotrophic methanogens increased, which broadening the pathway of methane production The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Recommanded Product: 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Smith, Paul C.;Huf, Joel P.;Williams, Christopher A. published 《Rocket Propellant Comparison: Conventional Planetary Mixing and Resonant Acoustic Mixing》 in 2022. The article was appeared in 《Propellants, Explosives, Pyrotechnics》. They have made some progress in their research.Related Products of 119-47-1 The article mentions the following:

A standard HTPB/AP/Al composite rocket propellant formulation was prepared with a conventional vertical planetary action mixer and resonant acoustic mixer (RAM). Ingredients and process conditions were standardised as much as possible to facilitate a direct comparison of the two process regimes. Cured propellant specimens were characterised for sensitiveness, ballistic properties and mech. properties at 3 temperatures (-54°C, 25°C and 74°C). No significant differences were noted for sensitiveness between the planetary and RAM mixes. A slightly lower burn rate at 1000 psi (6.89 MPa) was noted for the RAM mixes. Maximum stress results at 25°C were similar but significant differences in maximum strain and modulus were recorded. Maximum strain for the 1 Pt, 2 Gal and RAM were 7.4%, 9.1% and 17.6%, resp. Modulus results were 26.0 MPa, 19.3 MPa and 11.1 MPa, resp. Similar improvements in strain capability for the RAM propellant were recorded at -54°C and 74°C, with increases of 66% and 117%, resp. A greater strain capability results from stronger interfacial adhesion between the solid fill and the binder, which is in turn generally a result of improved wetting of solid particles. This result, therefore, indicates more thorough mixing in the case of the RAM process but this requires confirmation through a more direct examination of the underlying mechanism. And 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) was used in the research process.

Related Products of 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Qiao, Juanjuan;Lu, Gengyu;Wu, Gang;Liu, Hui;Wang, Wanli;Zhang, Tianmao;Xie, Guoyong;Qin, Minjian published 《Influence of different pretreatments and drying methods on the chemical compositions and bioactivities of Smilacis Glabrae Rhizoma》. The research results were published in《Chinese Medicine (London, United Kingdom)》 in 2022.Formula: C23H32O2 The article conveys some information:

The processing of medicinal plant materials is one of the important factors influencing the components and biol. activities of TCMs. Smilax glabra Roxb. is an herbal vine widely distributed in China, and its dried rhizome (Smilacis Glabrae Rhizoma, SGR) is often used in traditional medicines and functional foods. The processing methods of fresh cutting for SGR slices have been included in ancient Chinese herbal works, some local standards of TCMs, and the current Chinese Pharmacopoeia. Nevertheless, to date, the scientific basis for the processing of fresh medicinal materials for SGR slices has not been revealed. To optimize the processing method for preparing SGR slices from the fresh rhizomes, the chem. compositions of the un-pretreated and pretreated (boiling, steaming) samples before and after drying (sun-drying, shade-drying, oven-drying), and the contents of astilbin isomers in dried SGR were analyzed by UHPLC-Q-TOF-MS/MS and UHPLC-DAD methods, resp. Then, the antioxidant, anti-inflammatory, xanthine oxidase and α-glucosidase inhibitory activities of the prepared SGR slices were investigated by biol. assays. A total of fifty-two compounds were identified from the un-pretreated and pretreated samples and a total of forty-nine compounds were identified from the subsequently dried samples. After pretreated by boiling and steaming, the contents of neoastilbin, neoisoastilbin, and isoastilbin in the prepared samples all increased. As a quality marker of SGR, the content of astilbin was unchanged or decreased slightly compared with that in the un-pretreated samples. During the drying process, the contents of the four astilbin stereoisomers in the un-pretreated samples increased significantly, while those in the pretreated samples had a slight increase or decrease. The effects of different processing methods were sorted according to the bioactivities of the prepared SGR. As a result, SGR slices prepared with no pretreatment followed by a sun-drying process have a higher astilbin content, better bioactivities and more energy savings, representing the optimum processing method for SGR slices. This study reveals the scientific basis for the processing of fresh medicinal materials for SGR slices. The results provide scientific information for the quality control of SGR and its rational applications in herbal medicines and functional foods. And 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) was used in the research process.

Formula: C23H32O22,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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COA of Formula: C23H32O2In 2021, Tang, Shuqin;Chen, Yukun;Song, Guixian;Liu, Xiaotu;Shi, Yumeng;Xie, Qitong;Chen, Da published 《A Cocktail of Industrial Chemicals in Lipstick and Nail Polish: Profiles and Health Implications》. 《Environmental Science & Technology Letters》published the findings. The article contains the following contents:

Beauty products contain various industrial chems. to increase their functionality and appearance. The frequent use of beauty products may increase human exposure to industrial chems., but to date, their chem. components remain poorly characterized. Our work characterized the chem. components in lipstick and nail polish by screening for a total of 231 chems. from seven categories, including organophosphate esters (OPEs), phthalate esters (PAEs), non-PAE plasticizers, bisphenol analogs, parabens, UV stabilizers, and antioxidants. Their total concentrations ranged from 38.9 to 3810 μg/g (median of 193 μg/g) and from 18.6 to 1910 μg/g (307 μg/g) in lipstick (n = 34) and nail polish (n = 15), resp. The chem. compositions differed between lipstick and nail polish, but non-PAE plasticizers generally dominated over other groups of chems. A number of emerging plasticizers, OPEs, and UV stabilizers have rarely been reported in personal care products or environmental samples but were found at very high levels in beauty products, raising concern about their environmental release and human exposure risk. Although the employment of a hazard quotient approach suggested low health risks for exposure to industrial chems. from the use of beauty products, potential mixture effects from the chem. cocktail and occupational exposure to beauty products should not be overlooked. To complete the study, the researchers used 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

COA of Formula: C23H32O22,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Qin, Junhao;Zeng, Shuqing;Wang, Xi;Lin, Chuxia published 《Generation of micro(nano)plastics and migration of plastic additives from Poly(vinyl chloride) in water under radiation-free ambient conditions》. The research results were published in《Chemosphere》 in 2022.Application In Synthesis of 2,2-Methylenebis(6-tert-butyl-p-cresol) The article conveys some information:

A batch experiment was conducted to observe the liberation of micro- and nano-sized plastic particles and plastic additive-originated organic compounds from poly(vinyl chloride) under radiation-free ambient conditions. The weathering of PVC films in deionized water resulted in isolated pockets of surface erosion. Addnl. OH from Fenton reaction enhanced PVC degradation and caused cavity erosion. The detachment of plastic fragments from the PVC film surfaces was driven by autocatalyzed oxidative degradation Over 90% of micro-sized plastic particles were <60 μm in length. The detached plastic fragments underwent intensified weathering, which involved strong dehydrochlorination and oxidative degradation Further fragmentation of micro-sized particles into nano-sized particles was driven by oxidative degradation with complete dehydrochlorination being achieved following formation of nanoplastics. 20 organic compounds released from the PVC films into the solutions were identified. And some of them can be clearly linked to common plastic additives. In the presence of addnl. OH, the coarser nanoplastic particles (>500 nm) tended to be rapidly disintegrated into finer plastic particles (<500 nm), while the finest fraction of nanoplastics (<100 nm) could be completely decomposed and disappeared from the filtrates. The micro(nano)plastics generated from the PVC weathering were highly irregular in shape. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Application In Synthesis of 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Quality Control of 2,2-Methylenebis(6-tert-butyl-p-cresol)《Experimental investigation on the oxidation of printing ink wastewater under hydrothermal flames》 was published in 2021. The authors were Zhang, Fengming;Li, Yufeng;Liang, Zhaojian;Wu, Tong;Huang, Yingfei, and the article was included in《Journal of Environmental Chemical Engineering》. The author mentioned the following in the article:

Printing ink wastewater has a strong color and contains high salinity and high concentrations of complex organic compounds, posting a severe threat to the ecol. environment and human health. In this work, supercritical water oxidation of printing ink wastewater is performed within a transpiring wall reactor (TWR) to avoid corrosion and salt plugging issues. The high concentration of organic matter in printing ink wastewater is used to form hydrothermal flames for enhanced degradation Flame temperatures, gaseous and aqueous products characteristics, as well as the anti-corrosion and salt plugging performance of the reactor, are obtained. A remarkable temperature fluctuation due to the multi-component systems indicates the instability of hydrothermal flame. The salt recovery rate of 94.56% and the integrity of the porous tube inner wall indicate that TWR has a good performance in terms of anti-corrosion and salt plugging. Under typical conditions, the removal rates for COD, total nitrogen, and color are 99.52%, 70.07%, and 97.89%, resp. Alkanes, nitrogenous compounds, benzodiazepines, and heterocyclic compounds in the aqueous products, and CO, H₂, NH₃, and CH₄ in the gaseous products are the main intermediate products of printing ink wastewater under hydrothermal flames. Ammonia nitrogen, as the main intermediate product, inhibits the complete oxidation of nitrogenous organic compounds Addnl., higher KNO₃ concentrations promote the complete oxidation of nitrogenous organic compounds, while higher NaOH concentrations can increase the pH value and slightly facilitate degradation In addition, higher feed flow rates prevent deposition and adhesion of additives that occur at high concentrations And 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) was used in the research process.

Quality Control of 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Name: 2,2-Methylenebis(6-tert-butyl-p-cresol)《Effects of Lactobacillus plantarum and Saccharomyces cerevisiae co-fermentation on the structure and flavor of wheat noodles》 was published in 2022. The authors were Ge, Zhenzhen;Wang, Weijing;Xu, Mingyue;Gao, Shanshan;Zhao, Yuxiang;Wei, Xiaopeng;Zhao, Guangyuan;Zong, Wei, and the article was included in《Journal of the Science of Food and Agriculture》. The author mentioned the following in the article:

Although traditional fermented noodles possess high eating quality, it is difficult to realize large-scale industrialization as a result of the complexity of spontaneous fermentation In present study, com. Lactobacillus plantarum and Saccharomyces cerevisiae were applied in the preparation of fermented noodles. The changes in the structural characteristics and aroma components of noodles after fermentation were investigated via SEM (SEM), Fourier transform IR spectroscopy (FTIR), low-field magenetic resonance imaging, electronic nose, and simultaneous distillation and extraction/gas chromatog.-mass spectrometry (GC-MS) anal. SEM images revealed that co-fermentation of the L. plantarum and S. cerevisiae for 10-40 min enhanced the continuity of the gluten network and promoted the formation of pores. FTIR spectra anal. showed that the co-fermentation increased significantly (P < 0.05) the proportion of α-helixes of noodles gluten protein, enhancing the orderliness of the mol. structure of protein. After fermentation for 10-40 min, the signal d. of hydrogen protons increased from the surface to the core, indicating that the water in the noodles migrated inward during a short fermentation process. The results of multivariate statistical anal. demonstrated that the main aroma differences between unfermented and fermented noodles were mainly in hydrocarbons, aromatic compounds and inorganic sulfides. GC-MS anal. indicated that the main volatile compounds detected were 2, 4-di-tert-butylphenol, bis (2-ethylhexyl) adipate, Bu acetate, di-Bu phthalate, dioctyl terephthalate, bis (2-ethylhexyl) phthalate, pentanol and 2-pentylfuran, etc. Co-fermentation with L. plantarum and S. cerevisiae improved the structure of gluten network and imparted more desirable volatile components to wheat noodles. 2022 Society of Chem. Industry. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Name: 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Scharinger, Fabian;Palvolgyi, Adam Mark;Weisz, Melanie;Weil, Matthias;Stanetty, Christian;Schnuerch, Michael;Bica-Schroder, Katharina published 《Sterically Demanding Flexible Phosphoric Acids for Constructing Efficient and Multi-Purpose Asymmetric Organocatalysts》. The research results were published in《Angewandte Chemie, International Edition》 in 2022.SDS of cas: 119-47-1 The article conveys some information:

A novel approach for various asym. transformations of cyclic enones, e.g., 2-cyclohepten-1-one has been described. The combination of readily accessible chiral diamines and sterically demanding flexible phosphoric acids resulted in a simple and highly tunable catalyst framework. The careful optimization of the catalyst components led to the identification of a particularly powerful and multi-purpose organocatalyst, which was successfully applied for asym. epoxidations, aziridinations, aza-Michael-initiated cyclizations, as well as for a novel Robinson-like Michael-initiated ring closure/aldol cyclization. High catalytic activities and excellent stereocontrol were observed for all four reaction types, indicating the excellent versatility of the catalytic system. Furthermore, a simple change in the diamine’s configuration provided easy access to both product antipodes in all cases. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

SDS of cas: 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Name: 2,2-Methylenebis(6-tert-butyl-p-cresol)《Effects of Lactobacillus plantarum and Saccharomyces cerevisiae co-fermentation on the structure and flavor of wheat noodles》 was published in 2022. The authors were Ge, Zhenzhen;Wang, Weijing;Xu, Mingyue;Gao, Shanshan;Zhao, Yuxiang;Wei, Xiaopeng;Zhao, Guangyuan;Zong, Wei, and the article was included in《Journal of the Science of Food and Agriculture》. The author mentioned the following in the article:

Although traditional fermented noodles possess high eating quality, it is difficult to realize large-scale industrialization as a result of the complexity of spontaneous fermentation In present study, com. Lactobacillus plantarum and Saccharomyces cerevisiae were applied in the preparation of fermented noodles. The changes in the structural characteristics and aroma components of noodles after fermentation were investigated via SEM (SEM), Fourier transform IR spectroscopy (FTIR), low-field magenetic resonance imaging, electronic nose, and simultaneous distillation and extraction/gas chromatog.-mass spectrometry (GC-MS) anal. SEM images revealed that co-fermentation of the L. plantarum and S. cerevisiae for 10-40 min enhanced the continuity of the gluten network and promoted the formation of pores. FTIR spectra anal. showed that the co-fermentation increased significantly (P < 0.05) the proportion of α-helixes of noodles gluten protein, enhancing the orderliness of the mol. structure of protein. After fermentation for 10-40 min, the signal d. of hydrogen protons increased from the surface to the core, indicating that the water in the noodles migrated inward during a short fermentation process. The results of multivariate statistical anal. demonstrated that the main aroma differences between unfermented and fermented noodles were mainly in hydrocarbons, aromatic compounds and inorganic sulfides. GC-MS anal. indicated that the main volatile compounds detected were 2, 4-di-tert-butylphenol, bis (2-ethylhexyl) adipate, Bu acetate, di-Bu phthalate, dioctyl terephthalate, bis (2-ethylhexyl) phthalate, pentanol and 2-pentylfuran, etc. Co-fermentation with L. plantarum and S. cerevisiae improved the structure of gluten network and imparted more desirable volatile components to wheat noodles. 2022 Society of Chem. Industry. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Name: 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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