Category: 1139-46-4

Raus, Vladimir published the artcileATRP of POSS Monomers Revisited: Toward High-Molecular Weight Methacrylate-POSS (Co)Polymers, Related Products of alcohols-buliding-blocks, the publication is Macromolecules (Washington, DC, United States) (2014), 47(21), 7311-7320, database is CAplus.

For the first time, ATRP was successfully employed for homopolymerization of a com. methacrylate-functionalized polyhedral oligomeric silsesquioxane (POSS) monomer, iBuPOSSMA, to high mol. weights It was found that iBuPOSSMA has a low ceiling temperature (T_c); therefore, low temperatures and/or high initial monomer concentrations need to be used in order to avoid low ds.p. that had been observed previously. The values of T_c, as well as of the polymerization enthalpy ΔH_p and entropy ΔS_p were determined to be 130° (at [M]₀ = 1 M), -41 kJ mol^-1, and -101 J mol^-1 K^-1, resp. Under optimized conditions, poly(iBuPOSSMA) homopolymers having low dispersity and high M_n, ranging from 23 000 to 460 000, were obtained in a well-controlled ATRP process. Moreover, various block copolymers having high-M_n poly(iBuPOSSMA) blocks were prepared by copolymerization of iBuPOSSMA with Me methacrylate and styrene.

Macromolecules (Washington, DC, United States) published new progress about 1139-46-4. 1139-46-4 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Phenol, name is 4-(2,4,4-Trimethylpentan-2-yl)benzene-1,2-diol, and the molecular formula is C14H22O2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Barr, Rita published the artcileElectron donation to the plasma membrane redox system of cultured carrot cells stimulates proton release, Synthetic Route of 1139-46-4, the publication is Biochimica et Biophysica Acta, Bioenergetics (1990), 1017(1), 91-5, database is CAplus and MEDLINE.

Membrane-permeable electron donors, duroquinol, diphenylcarbazide, pyrocatechol, and tert-octylcatechol, promoted both reduction of an impermeant electron acceptor and proton transport with cultured carrot cells. These cells were preloaded with electron donors for 15, 30, 45, and 60 min. Aliquots of cells were removed at various times, washed free of excess electron donors and assayed for their effect on transplasma membrane redox with impermeable hexacyanoferrate (HCF III) as the electron acceptor and for simultaneous H⁺ excretion in the presence of hexacyanoferrate. All four electron donors stimulated HCF III reduction and associated H⁺ excretion. Below a rate of hexacyanoferrate reduction of 6 μmol/g dry weight per min, the ratios of H⁺/e^– were between 0.3 and 1 with low concentrations (0.1 mM) of the added electron donors. When hexacyanoferrate reduction exceeded 6 μmol/g dry weight per min, H⁺ release began to cascade to give ratios of 1 to 3, suggesting activation of an H⁺-ATPase or a proton transporter. This behavior by cultured carrot cells indicates that a certain threshold of proton concentration in a limited membrane domain must be reached in order for the proton channel to be opened.

Biochimica et Biophysica Acta, Bioenergetics published new progress about 1139-46-4. 1139-46-4 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Phenol, name is 4-(2,4,4-Trimethylpentan-2-yl)benzene-1,2-diol, and the molecular formula is C14H22O2, Synthetic Route of 1139-46-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Crane, F. L. published the artcileStimulation of photosynthesis by carbonyl compounds and chelators, Application In Synthesis of 1139-46-4, the publication is Biochemical and Biophysical Research Communications (1977), 74(4), 1362-8, database is CAplus and MEDLINE.

A number of carbonyl compounds including HCO3-, ethylene carbonate, dimethyl carbonate, propylene carbonate, bis(pentamethylene)urea, and glycidol, and several chelators were tested for their effect on photosynthetic reactions in isolated spinach chloroplasts. Carbonyl compounds inhibited the DCMU-insensitive silicomolybdate reduction by photosystem II but stimulated the O evolution associated with ferricyanide reduction in the presence of DBMIB and the H2O �methylviologen reaction. Many chelators behaved in the same manner except 1,10-phenanthroline which showed the opposite effect. The carbonyl compounds did not uncouple because they stimulated the proton gradients associated with noncyclic photophosphorylation, whereas some chelators, such as bathocuproine or bathophenanthroline inhibited the proton gradients 100%. Electron transport in the presence of ADP and inorganic phosphate showed a stimulation of rates beyond that obtained in presence of an uncoupler. The data are discussed in terms of inhibition of cyclic electron flow around photosystem II which leads to increased electron transport rates toward photosystem I.

Biochemical and Biophysical Research Communications published new progress about 1139-46-4. 1139-46-4 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Phenol, name is 4-(2,4,4-Trimethylpentan-2-yl)benzene-1,2-diol, and the molecular formula is C14H22O2, Application In Synthesis of 1139-46-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Thorsteinson, Nels published the artcileIn silico identification of anthropogenic chemicals as ligands of zebrafish sex hormone binding globulin, Quality Control of 1139-46-4, the publication is Toxicology and Applied Pharmacology (2009), 234(1), 47-57, database is CAplus and MEDLINE.

Anthropogenic compounds with the capacity to interact with the steroid-binding site of sex hormone binding globulin (SHBG) pose health risks to humans and other vertebrates including fish. Building on studies of human SHBG, the authors have applied in silico drug discovery methods to identify potential binders for SHBG in zebrafish (Danio rerio) as a model aquatic organism. Computational methods, including; homol. modeling, mol. dynamics simulations, virtual screening, and 3D QSAR anal., successfully identified 6 non-steroidal substances from the ZINC chem. database that bind to zebrafish SHBG (zfSHBG) with low-micromolar to nanomolar affinities, as determined by a competitive ligand-binding assay. The authors also screened 80,000 com. substances listed by the European Chems. Bureau and Environment Canada, and 6 non-steroidal hits from this in silico screen were tested exptl. for zfSHBG binding. All 6 of these compounds displaced the [³H]5α-dihydrotestosterone used as labeled ligand in the zfSHBG screening assay when tested at a 33 μM concentration, and 3 of them (hexestrol, 4-tert-octylcatechol, and dihydrobenzo(a)pyren-7(8H)-one) bind to zfSHBG in the micromolar range. The study demonstrates the feasibility of large-scale in silico screening of anthropogenic compounds that may disrupt or highjack functionally important protein:ligand interactions. Such studies could increase the awareness of hazards posed by existing com. chems. at relatively low cost.

Toxicology and Applied Pharmacology published new progress about 1139-46-4. 1139-46-4 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Phenol, name is 4-(2,4,4-Trimethylpentan-2-yl)benzene-1,2-diol, and the molecular formula is C18H17N5O3, Quality Control of 1139-46-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts