Category: 111-87-5

Lv, Jing published the artcileRelationships between bacterial community and metabolites of sour meat at different temperature during the fermentation., Product Details of C8H18O, the main research area is Lactobacillus lactic amino acid fermentation temperature sour meat; Amino acid; Flavor; Microbial community; Sour meat fermentation; Temperature; Volatile organic compound.

This study was designed to explore the temperature effects on bacterial communities and metabolites, as well as their relationships during the fermentation of sour meat, a traditional fermented meat product in the ethnic minority regions of China. Results showed that reduction of pH and increase of lactic acid and free amino acid contents occurred (p < 0.05) as the fermentation temperature and time increased, and the tendency was more apparent at higher temperature During the fermentation, Lactobacillus gradually replaced other genera, and higher the temperature, more rapid was the process. Both the number and amount of volatile organic compounds increased at higher temperatures Hexanal, benzaldehyde, nonanal, (E,E)-2,4-decadienal, 1-octen-3-ol and octanal were identified as the key volatile organic compounds produced by Lactobacillus in sour meat as main contributors to odor as confirmed by variable importance in the projection anal. Redundancy anal. and Pearson correlation showed pos. correlation between Lactobacillus and desired product characteristics, such as higher content of lactic acid, free amino acids, volatile organic compounds, and lower pH and water activity values, which may represent a better quality and longer shelf life after fermentation at higher temperature Therefore fermentation at 20°C and 25°C are proposed as optimum temperatures for sour meat production International Journal of Food Microbiology published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Product Details of C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Niu, Feng published the artcileAlcohol amination over titania-supported ruthenium nanoparticles, Application In Synthesis of 111-87-5, the main research area is alc amination titania supported ruthenium nanoparticle.

Metal nanoparticles for heterogeneous catalytic reactions are often supported on porous materials. The catalytic performance of supported catalysts usually depends on the size of the metal nanoparticles and catalytic supports. Selective synthesis of valuable primary amines is an important target in the modern industry. In this work, the catalytic performance of TiO2 supported Ru nanoparticles with sizes from 1.4 to 9.9 nm was investigated in both direct gas-phase amination of 1-butanol and liquid-phase amination of 1-octanol into primary amines in the presence of ammonia. Our results suggest that ruthenium nanoparticle size is one of the most important parameters, which affects the catalytic performance of titania supported catalysts in the amination reactions. The selectivity to primary amines is much higher over smaller supported Ru nanoparticles than over larger ones, especially in the liquid-phase amination of 1-octanol. The 95% selectivity to octylamine is obtained over small supported Ru nanoparticles with a diameter of 1.4 nm even at 95% conversion, whereas for larger Ru nanoparticles, the octylamine selectivity drops as the 1-octanol conversion approached 80-90%. The drop of the selectivity to octylamine at higher conversion is due to the increase in the intrinsic rate of octylamine coupling over larger ruthenium nanoparticles. The support can also contribute to some extent to the rate of primary amine self-coupling, while its effect on the overall catalytic performance is not significant for the titania-supported catalysts.

Catalysis Science & Technology published new progress about Alcohols Role: PEP (Physical, Engineering or Chemical Process), PROC (Process). 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application In Synthesis of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Prajapati, Ritu published the artcileIsoliquiritigenin, a potent human monoamine oxidase inhibitor, modulates dopamine D1, D3, and vasopressin V1A receptors, Computed Properties of 111-87-5, the main research area is isoliquiritigenin human monoamine oxidase inhibitor dopamine vasopressin VA receptor.

Isoliquiritigenin (= 4,2′,4′-Trihydroxychalcone) (ILG) is a major constituent of the Glycyrrhizae Rhizoma that has significant neuroprotective functions. In the present study, we re-examined the potential of ILG to inhibit human monoamine oxidase (hMAO) in vitro and established its mechanism of inhibition through a kinetics study and mol. docking examination ILG showed competitive inhibition of hMAO-A and mixed inhibition of hMAO-B with IC50 values of 0.68 and 0.33μM, resp., which varied slightly from the reported IC50 values. Since ILG has been reported to reduce dopaminergic neurodegeneration and psychostimulant-induced toxicity (both of which are related to dopamine and vasopressin receptors), we investigated the binding affinity and modulatory functions of ILG on dopamine and vasopressin receptors. ILG was explored as an antagonist of the D1 receptor and an agonist of the D3 and V1A receptors with good potency. An in silico docking investigation revealed that ILG can interact with active site residues at target receptors with low binding energies. These activities of ILG on hMAO and brain receptors suggest the potential role of the compound to ameliorate dopaminergic deficits, depression, anxiety, and associated symptoms in Parkinson’s disease and other neuronal disorders.

Scientific Reports published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Computed Properties of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gonzalez-Alvarez, Rafael Jesus published the artcileA handling-free methodology for rapid determination of Cu species in seawater based on direct solid micro-samplers analysis by high-resolution continuum source graphite furnace atomic absorption spectrometry, Related Products of alcohols-buliding-blocks, the main research area is rapid copper species seawater solid microsampler; resolution continuum source graphite furnace atomic absorption spectrometry; Continuum source solid sampling graphite furnace atomic absorption spectrometry; Copper speciation; Direct determination; Seawater; Solvent bar.

A simple, sensible and advanced new methodol. for the determination of copper species in seawater was developed. The method consisted of two steps: first a separation/preconcentration of copper species by using liquid phase microextraction-based solvent bars followed by the direct anal. of these solid polymeric micro-samplers in an at. absorption spectrometer provided with a device for direct anal. For liquid microextraction, di-2-pyridylketone benzoylhydrazone (dPKBH) dissolved in octan-1-ol was selected as the extracting agent due to its ability to transport inorganic Cu species from seawater samples. The optimum chem. and phys. conditions for copper micro-extraction were sample pH 8, a dPKBH concentration of 0.010 mol L-1, a stirring speed of 800 rpm and an extraction time of 10 min. A graphite furnace temperature program was optimized to assure the complete elimination of the solvent bar matrix, and the atomization step took place at 2200°. The method exhibited a limit of detection of 0.026 μg L-1 of copper and a linear range up to 1.50 μg L-1, showing great repeatability and reproducibility (4.07% and 4.43%, resp.). Suitability of the method was confirmed by analyzing a certified reference material (CASS-4) under optimum conditions, being the first time ever that a direct solid anal.-based method was used for the determination of total dissolved copper concentration in seawater. Furthermore, the method was applied to the determination of the operationally defined transportable Cu fraction in seawater samples at natural conditions and the results were compared with theor. data provided by Visual MINTEQ 3.1 software. A math. model that permits to estimate total dissolved copper concentration was obtained, and the non-transportable copper fraction was calculated by difference.

Talanta published new progress about High-resolution continuum source graphite furnace atomic absorption spectroscopy. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ozyagci, Bensu published the artcileEsterification of 1-Octanol on Clinoptilolite-Supported TiO2 Catalysts, Safety of n-Octanol, the main research area is octanol clinoptilolite supported titanium oxide catalyst esterification.

In this study, a natural type of zeolite, Clinoptilolite (CLI), is used as a support for TiO2. First, TiO2-supported heterogeneous catalysts originated from the high temperature calcination of TiCl4 groups, which were thermally immobilized on clinoptilolite, were obtained. Powder-XRD and EDX analyzes showed that the oxide form of Ti-immobilized on dealuminated clinoptilolite were formed in the anatase phase, and the zeolite structure was preserved. As seen in TGA/DTA analyzes, this catalyst could be efficient and have high stability for many reactions. Second, the esterification reaction of 1-octanol with acetic acid is used as a reference reaction for this catalyst.

Silicon published new progress about Clinoptilolite-type zeolites Role: CAT (Catalyst Use), USES (Uses) (dealuminated). 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Safety of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tan, Sze Chieh published the artcileA metal-organic framework of type MIL-101(Cr) for emulsification-assisted micro-solid-phase extraction prior to UHPLC-MS/MS analysis of polar estrogens, Recommanded Product: n-Octanol, the main research area is polar estrogen UHPLC MS micro solid phase extraction review; Endocrine disrupting compounds; Environmental water; Hormones; Liquid chromatography-tandem mass spectrometry; Membrane-protected; Microextraction; Porous material; Sample preparation.

A seamless two-step extraction procedure integrating ultrasound-assisted emulsification microextraction (USAEME) and vortex-assisted micro-solid-phase extraction (μ-SPE) was developed. A highly porous metal-organic framework of type MIL-101(Cr) is used as the sorbent, and ultra-high-performance liquid chromatog. in combination with tandem mass spectrometry is used for detection. The steroid hormones estrone 17β-estradiol, estriol, and 17α-ethynylestradiol were extracted from water samples by using this method. These steroids are polar and do not pass through the polypropylene membrane that is conventionally used in μ-SPE. In the method presented here, 1-octanol is used in USAEME to extract and pre-concentrate the steroids. This facilitates the transfer to the MIL-101(Cr) phase retained by the membrane in the subsequent μ-SPE step. MIL-101(Cr) was characterized by various methods, and the parameters affecting the overall extraction efficiency were optimized. Under the most favorable conditions, the limits of detection are between 0.95 and 23 ng L-1. Good intra-day and inter-day precisions were obtained, with relative standard deviations of ≤ 9.9%. Enrichment factors are between 34 and 52. The method was applied to genuine environmental water samples in which estrone was detected. Relative recoveries ranged between 85.4% and 120.8%. [Figure not available: see fulltext.].

Microchimica Acta published new progress about Activated charcoal Role: TEM (Technical or Engineered Material Use), USES (Uses). 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Recommanded Product: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Demmelmayer, Paul published the artcileReactive extraction of lactic acid from sweet sorghum silage press juice, Name: n-Octanol, the main research area is sorghum silage lactic acid equilibrium juice.

Fermentation of residues or side streams can be used to produce valuable products, such as carboxylic acids. Reactive solvent extraction is widely studied as isolation method for lactic acid from fermentation broths. Here, we investigate the reactive extraction of lactic acid from sweet sorghum silage press juice using different extractants, modifiers, and diluents. Besides a high extraction efficiency, a low crud formation with this highly complex raw material is targeted. Depending on the solvent phase composition, an extraction efficiency of up to 41.1% was reached using DOA/ALIQ:1-octanol:n-nonane. The crud layer was highly influenced by the applied diluent and amounted to 2.6-42.3 vol% of the total mixture volume The back-extraction experiments showed, that up to 98.2% of lactic acid were recovered. Summarizing, the results show that reactive solvent extraction of lactic acid is applicable to highly complex process streams, and crud formation can be reduced by adjusting the solvent phase composition

Separation and Purification Technology published new progress about Carboxylic acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Name: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Czyrski, Andrzej published the artcileThe spectrophotometric determination of lipophilicity and dissociation constants of ciprofloxacin and levofloxacin, Application of n-Octanol, the main research area is ciprofloxacin levofloxacin spectrophotometry lipophilicity; Distribution; Lipophilicity; Partition coefficient; Partitioning.

Lipophilicity plays a significant role in the permeability of the drugs through cell membranes and impacts the drug activity in the human body. In this paper, the spectrophotometric method was used to determine the apparent partition coefficients of two amphoteric drugs: ciprofloxacin and levofloxacin. The apparent partition coefficient was determined with the classic shake-flask method with n-octanol according to OECD guidelines. The lipophilicity profiles in a wide range of pH were determined and described quant. with the quadratic function. Basing on the macro- and microdissocn. constants, the true partition coefficient for both drugs was calculated Both levofloxacin and ciprofloxacin were lipophilic. The neutral forms, i.e., zwitterionic and uncharged, dominate in the pH relevant to the one in the intestines, the place from which they are absorbed.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about Fluoroquinolones Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Na, Mihwa published the artcileSingle-Neuron Comparison of the Olfactory Receptor Response to Deuterated and Nondeuterated Odorants, Recommanded Product: n-Octanol, the main research area is deuterium odorant GPCR olfactory receptor sensory neuron olfaction; GPCR; Olfactory receptor; aldehyde; calcium imaging; deuterium; odorant receptor.

The mammalian olfactory receptors (ORs) constitute a large subfamily of the Class A G-protein coupled receptors (GPCRs). The mol. details of how these receptors convert odorant chem. information into neural signal are unknown, but are predicted by analogy to other GPCRs to involve stabilization of the activated form of the OR by the odorant. An alternative hypothesis maintains that the vibrational modes of an odorant’s bonds constitute the main determinant for OR activation, and that odorants containing deuterium in place of hydrogen should activate different sets of OR family members. Experiments using heterologously expressed ORs have failed to show different responses for deuterated odorants, but experiments in the sensory neuron environment have been lacking. We tested the response to deuterated and nondeuterated versions of p-cymene, 1-octanol, 1-undecanol, and octanal in dissociated mouse olfactory receptor neurons (ORNs) by calcium imaging. In all, we tested 23 812 cells, including a subset expressing recombinant mouse olfactory receptor 2 (Olfr2/OR-I7), and found that nearly all of the 1610 odorant-responding neurons were unable to distinguish the D- and H-odorants. These results support the conclusion that if mammals can perceive deuterated odorants differently, the difference arises from the receptor-independent steps of olfaction. Nevertheless, 0.81% of the responding ORNs responded differently to D- and H-odorants, and those in the octanal experiments responded selectively to H-octanal at concentrations from 3 to 100 μM. The few ORs responding differently to H and D may be hypersensitive to one of the several H/D physicochem. differences, such as the difference in H/D hydrophobicity.

ACS Chemical Neuroscience published new progress about G protein-coupled receptors Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Recommanded Product: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sharma, Kusha published the artcileEntrapment and release kinetics study of dyes from BSA microspheres forming a matrix and a reservoir system, HPLC of Formula: 111-87-5, the main research area is albumin microsphere dissolution encapsulation.

Two kinds of Bovine Serum Albumin (BSA)-loaded microspheres were prepared in water-organic bilayer systems using ultrasonic irradiation The first method included an aqueous solution of BSA and water-soluble dye together, mixed with dodecane, that upon sonication formed a matrix system where the dye is concentrated in the protein shell. The other system included an aqueous solution of BSA mixed with octanol-soluble dye that, upon sonication, formed a reservoir system in which the dye filled the inner volume of the microspheres. Each of these microspheres was prepared with two different dyes and their leaching profiles into pure solvents were studied using UV-vis spectrometry. Fast leaching was observed at the beginning for both systems, which leveled-off after a certain time. For the matrix system, an equilibrium state was obtained after 100-200 h, whereas for the reservoir system, leaching occurred much faster, within 1-3 h. Such systems can serve as models for drug delivery agents.

Journal of Materials Chemistry B: Materials for Biology and Medicine published new progress about Blood serum albumins Role: THU (Therapeutic Use), BIOL (Biological Study), USES (Uses). 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, HPLC of Formula: 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts