Category: 111-46-6

Effect of polar groups of polystyrenes on the self-assembly of breath figure arrays was written by Zhou, Di;Wu, Bai-Heng;Yang, Wen-Wu;Li, Xiao;Zhu, Liang-Wei;Xu, Zhi-Kang;Wan, Ling-Shu. And the article was included in Journal of Polymer Science (Hoboken, NJ, United States) in 2022.Recommanded Product: 2,2′-Oxybis(ethan-1-ol) This article mentions the following:

The breath figure (BF) process has been widely used to prepare patterned porous films. The mechanism remains to be further elucidated, especially how polymer architectures affect the stability of water droplets and the pore structure. Polystyrenes (PS) was functionalized with a series of polar groups both in chain middle and chain end, which was synthesized by using difunctional atom transfer radical polymerization (ATRP) initiators with the combination of nucleophilic substitution of the end bromine. It is found that PS with polar groups, which help to reduce interfacial tension, tends to form regular patterns at low concentration and to generate multilayered pores. The coalescence resistance measurement was performed to characterize the stabilization of water droplets from polymers by precipitation The results show opposite trend with the results of the BF process, indicating a minor role played by polymer precipitation on microdroplets stabilization. We reveal that addition of only an oxyethyl group in the chain middle of PS contributes to the formation of ordered patterns. This study helps to shed light on the impact of polymer architectures on the self-assembly behavior in the BF process. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Recommanded Product: 2,2′-Oxybis(ethan-1-ol)).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 2,2′-Oxybis(ethan-1-ol)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Preparation of Natural Rubber Composites with High Silica Contents Using a Wet Mixing Process was written by Phumnok, Ekaroek;Khongprom, Parinya;Ratanawilai, Sukritthira. And the article was included in ACS Omega in 2022.Application of 111-46-6 This article mentions the following:

A wet mixing process is proposed for filled rubber composites with a high silica loading to overcome the drawbacks of high energy consumption and workplace contamination of the conventional dry mixing process. Ball milling was adopted for preparing the silica dispersion because it has a simple structure, is easy to operate, and is a low-cost process that can be easily scaled up for industrial production The response surface methodol. was used to optimize the making of the silica dispersion. The optimum conditions for a well-dispersed silica suspension with the smallest silica particle size of 4.9 mm were an about 22% silica content and 62 h of ball milling. The effects of dry and wet mixing methods on the properties of silica-filled rubber composites were investigated in a broad range of silica levels from low to high loadings. The mixing method choice had little impact on the properties of rubber composites with low silica loadings. The silica-filled rubber demonstrated in this study, however, shows superior characteristics over the rubber composite prepared with conventional dry mixing, particularly with high silica loadings. When compared to silica-filled natural rubbers prepared by dry mixing (dry silica rubber, DSR), the wet mixing (for WSR) produced smaller silica aggregates with better dispersion. Due to the shorter heat history, the WSR exhibits superior curing characteristics such as a longer scorch time (2.2-3.3 min for WSR and 1.0-2.1 min for DSR) and curing time (4.1-4.5 min for WSR and 2.2-3.1 min for DSR). Addnl., the WSR has superior mech. properties (hardness, modulus, tensile strength, and especially the elongation at break (420-680% for WSR and 360-620% DSR)) over the DSR. The rolling resistance of WSR is lower than that of DSR. However, the reversed trend on the wet skid resistance is observed In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Application of 111-46-6).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application of 111-46-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of lathyrane diterpenoid nitrogen-containing heterocyclic derivatives and evaluation of their anti-inflammatory activities was written by Wang, Wang;Xiong, Liangliang;Li, Yutong;Song, Zhuorui;Sun, Dejuan;Li, Hua;Chen, Lixia. And the article was included in Bioorganic & Medicinal Chemistry in 2022.Reference of 111-46-6 This article mentions the following:

As our ongoing work on lathyrane diterpenoid derivatization, three series of lathyrane diterpenoid derivatives were designed and synthesized based combination principles, including pyrazole, thiazole and furoxan moieties I [R = Et, phenyl; R¹ = Me, Cl, F, etc], II [R² = Me, Ph, cyclohexyl, etc.] and III [R³ = Bu, butyne, 1,4-dimethylbenzene, etc.] . Biol. evaluation indicated that compound III [R³ = ethoxyethane] exhibited excellently inhibitory activity on LPS-induced NO production in RAW264.7 cells (IC₅₀ = 0.38 ± 0.18 μM). The preliminary structure-activity relationships (SARs) suggested that phenylsulfonyl substituted furoxan moiety had the strongest ability to improve anti-inflammatory activity of lathyrane diterpenoids. Furthermore, compound III [R³ = ethoxyethane] significantly reduced the level of ROS. Its mol. mechanism was related to inhibiting the transcriptional activation of Nrf₂/HO-1 pathway. Based on these considerations, III [R³ = ethoxyethane] might be a promising anti-inflammatory agent, which is noteworthy for further exploration. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Reference of 111-46-6).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Reference of 111-46-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Design, synthesis and human carbonic anhydrase I, II, IX and XII inhibitory properties of 1,3-thiazole sulfonamides was written by Erigur, Esra Caner;Altug, Cevher;Angeli, Andrea;Supuran, Claudiu T.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2022.Synthetic Route of C4H10O3 This article mentions the following:

A series of novel 1,3-thiazole sulfonamides I [R = i-Pr, n-Bu, HOCH₂CH₂, Ph(CH₂)₄, etc.] has been designed, synthesized and studied their carbonic anhydrase (CA) inhibitory properties. The inhibition property of four human CA isoforms was investigated: hCA I, II, IX, and XII using the standard drug acetazolamide (AAZ) for comparison. The compounds I showed a wide range of inhibition potency towards the cytosolic enzyme hCA I. Nevertheless, the compounds I (R = n-Pr, i-Pr, HOCH₂CHMe, HOCHMeCH₂, MeOCH₂CH₂) have shown higher inhibition potential as compared to acetazolamide (KI = 250 nM). The abundant human cytosolic isoform, hCA II, was strongly inhibited by the most compounds in low nanomolar range (KI < 12.1 nM). On the other hand, almost all novel synthesized compounds have shown weaker inhibition potential as compared to acetazolamide against the tumor membrane- associated isoform hCA IX. Finally, the second tumor membrane-associated isoform, hCA XII, showed a wide range of potency that spanned from 9.3 to 729.6 nM. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Synthetic Route of C4H10O3).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Synthetic Route of C4H10O3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Humic substances measurement in sludge dissolved organic matter: A critical assessment of current methods was written by Xiao, Keke;Horn, Harald;Abbt-Braun, Gudrun. And the article was included in Chemosphere in 2022.Product Details of 111-46-6 This article mentions the following:

The role of humic substances (HS) during sludge treatment has been the focus in recent years. Quantification of HS in sludge dissolved organic matter (DOM) and the chem. and structural characterization of HS data are the prerequisite for understanding their role during different sludge treatment processes. Currently, a number of published articles inadequately acknowledge fundamental principles of anal. methods both in terms of exptl. approach and data anal. Therefore, a more comprehensive and detailed description of the exptl. methods and the data anal. are needed. In this study, the current used methods for HS quantification in DOM of sludge had been tested for different calibration and sludge DOM samples. The results indicated that the current methods showed overestimated and contradictory results for HS quantification in sludge DOM. To be specific, using the modified Lowry method, different values were obtained depending on the humic acids used for calibration, and false neg. results were observed for some sludge samples. By using the relative amount of HS (based on dissolved organic carbon (DOC)) to total sludge DOM (based on DOC), variations among the results of different anal. methods for the same sample were high. According to the calculated Bray-Curtis dissimilarity indexes, the results for HS quantification obtained by three-dimensional excitation emission matrix (3D-EEM), either with spectra anal. methods by peak picking, fluorescence region integration (both region volume and area integration), or PARAllel FACtor anal. showed higher degrees of dissimilarity to those quantified by size exclusion liquid chromatog. or XAD-8 method. The selection of fluorescence regions for HS seemed to be the determining factor for overestimation obtained by the 3D-EEM technique. In future work, strategies, like a consistent terminol. of HS, the use of an internal standard sample, and the related standardized operation for HS quantification in sludge DOM need to be established. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Product Details of 111-46-6).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Product Details of 111-46-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Isolation and identification of Lactobacillus and yeast species and their effect on the quality of fermented rice cakes was written by He, Li;Chen, Yanhua;Zhang, Haitian;Wang, Hui;Chen, Shujuan;Liu, Shuliang;Liu, Aiping;Li, Qin;Ao, Xiaolin;Liu, Yaowen. And the article was included in Innovative Food Science & Emerging Technologies in 2022.Related Products of 111-46-6 This article mentions the following:

In this study, microbes were isolated from the rice slurry of a fermented rice cake to obtain lactic acid bacteria and yeast species. These species were identified using microbial physiol. and gene sequence analyses. As the growth of the lactic acid bacterial strain R-2b and the yeast J-3a strains were found to be the best, a composite starter comprising these microbes was used for the preparation of fermented rice cakes. Based on single factor and orthogonal experiments, when the proportion of Lactobacillus plantarum, Saccharomyces cerevisiae, and Candida humilis was 1:3:6, the optimal fermentation conditions were addition of sugar and starter amounts of 20% and 6%, resp., a fermentation temperature of 32°C, and fermentation time of 8 h. The fermented rice cake with this optimum ratio had the most abundant volatile components and qualified physicochem. and microbial indexes. Addnl., the overall quality was better than that of com. available products. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Related Products of 111-46-6).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Related Products of 111-46-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

COSMO Study on the Heptane-Toluene-DMF/DEG-KSCN Liquid-Liquid Equilibrium System was written by Fernanda Bonfim de Souza, Beatriz;Lenhare, Stephanie;Cristaldo Heck, Stenio;Zuber, Andre;Beneti, Stephani Caroline;Zanette, Andreia Fatima;Filho, Lucio Cardozo. And the article was included in Industrial & Engineering Chemistry Research in 2022.Reference of 111-46-6 This article mentions the following:

The class of aromatic hydrocarbons is one of the most important in the petrochem. industry. As they are in a multicomponent mixture with aliphatics, separation represents a huge challenge given the proximity of their b.ps., and liquid-liquid extraction represents a good alternative to conventional separation processes. In this paper, liquid-liquid equilibrium data of a heptane-toluene-dimethylformamide (DMF)-diethylene glycol (DEG) system in the presence and absence of potassium thiocyanate salt were obtained and used to study solvation of ions in the DMF-DEG polar mixture solvent, using COnductor-like Screening MOdel (COSMO) modeling. It was verified that the solvation complexes failed to describe the system equilibrium despite the otherwise expected. COSMO-RS (realistic solvents) calculations of the unsolvated ions presented better approximation with exptl. data compared to COSMO-SAC (segment activity coefficient) ones. The best simulation obtained with nonsolvated ions occurred probably due to π electron interactions with ion charge and hydrogen bond with the solvent. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Reference of 111-46-6).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Reference of 111-46-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tuning magnetic heating efficiency of colloidal dispersions of iron oxide nano-clusters by varying the surfactant concentration during solvothermal synthesis was written by Ranoo, Surojit;Lahiri, B. B.;Damodaran, Shima P.;Philip, John. And the article was included in Journal of Molecular Liquids in 2022.Application of 111-46-6 This article mentions the following:

Magnetic fluid hyperthermia (MFH) is being actively sought as a supplementary cancer therapy, where enhancing the MFH efficiency is essential for reducing dosage and field exposure. Owing to the superior magnetic properties, magnetic nano-clusters (MNCs) are being developed as MFH agents, where the role of synthesis routes, colloidal stability and magneto-structural properties on MFH efficiency requires further attention. In this article, we report the tuning of MFH efficiency of water and diethylene glycol-based magnetic nanofluids containing iron-oxide MNCs of sizes ∼ 125 to 539 nm, obtained by varying the surfactant concentration Magnetite MNCs are prepared via solvothermal route, where the primary nano-crystallite (MNP) size is varied from 7.4 ± 0.7 to 25.0 ± 0.8 nm by reducing the sodium citrate (surfactant) concentration from 29 to 0.29 mg/mL. With decreasing surfactant concentration, the amount of sodium citrate absorbed on the surface of the freshly formed nano-seeds reduces, which lowers the electrostatic stabilization in polar media and favors the growth of larger MNPs that results in comparatively larger MNCs. Transmission electron microscopy and at. force microscopy based studies indicate the monodisperse spherical morphol. of the MNCs, consisting of several primary nano-crystallites. Room temperature isothermal magnetization measurements indicate high saturation magnetization and superparamagnetic nature of the MNCs, which are beneficial for MFH applications. Magneto-calorimetry experiments are performed for the accurate estimation of the MFH efficiency of the colloidal dispersions of the MNCs. Exptl. findings indicate that the heating efficiency increases from 15.24 ±1.22 to 193.8 ± 5.2 W/gFe (i.e., an enhancement of ∼ 12.7 times), at a field exposure condition of 33.1 kA/m and 126 kHz, when the primary nano-crystallite size is increased by ∼ 3.4 times by reducing the surfactant concentration It is observed that the heating efficiency decreases linearly with the logarithm of surfactant concentration in all the cases, which is attributed to the variations in primary nano-crystallite sizes and the resultant magnetic losses. Magneto-calorimetric experiments, using MNCs immobilized in high viscosity agar matrix, indicate insignificant contributions from the whole-scale Brownian relaxation, and the heating efficiency is found to be solely dependent on the magnetic losses of the primary nano-crystallites. With increasing primary nano-crystallite size, augmentation of heating efficiency is due to the increase in magnetization and dynamic coercivity, which is confirmed from theor. calculations using the high frequency hysteresis loops and sweeping rate modified Stoner Wohlfarth model. The obtained results indicate the possibility of tuning hyperthermia efficiency of MNCs by varying the surfactant concentration, which is beneficial for designing colloidally stable dispersions of MNCs with improved MFH efficiency. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Application of 111-46-6).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application of 111-46-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Self-healing modified liquefied lignocellulosic cross-linked bio-based polymer for controlled-release urea was written by Tian, Hongyu;Zhang, Lina;Sun, Xiao;Cui, Jing;Dong, Jingjing;Wu, Liang;Wang, Yanfeng;Wang, Lingli;Zhang, Min;Liu, Zhiguang;Lu, Panfang. And the article was included in Industrial Crops and Products in 2022.Computed Properties of C4H10O3 This article mentions the following:

Alkali-hydrolyzed lignocellulose was liquefied into polyols by acid-catalyzed dissolution, and then cross-linked with castor oil to prepare bio-based cross-linked polyurethane. Then, bis (2-hydroxyethyl) disulfide (SS) with self-healing function was used to reduce foaming in the curing process of polyurethane coating. Afterwards, disulfide bond modified crosslinked bio-based polyurethane coating (BCSPU) was applied to controlled-release urea (CRU). The results of excitation-emission matrixes indicated that SS made the coating smoother and denser and preventing the release of non-film-forming substances. Crosslinking modification technol. significantly extended the controlled release longevity of CRU by 77.3%, and the self-healing modification further prolonged the nitrogen release longevity by 61.5%. In addition, modified coating materials were non-toxic to wheat seeds and easily biodegradable in the soil. Crosslinking, self-healing modified controlled-release urea has enormous application potential in sustainable agriculture. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Computed Properties of C4H10O3).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Computed Properties of C4H10O3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Thiol-Yne click chemistry of acetylene-enabled macrocyclization was written by Lu, Shiwei;Wang, Zipeng;Zhu, Shifa. And the article was included in Nature Communications in 2022.Recommanded Product: 2,2′-Oxybis(ethan-1-ol) This article mentions the following:

Herein reported a photocatalyzed thiol-yne click reaction to forge diverse sulfur-containing macrocycles (up to 3,5-membered ring) and linear C2-linked 1,2-(S-S/S-P/S-N) functionalized mols., starting from the simplest alkyne, acetylene. Preliminary mechanistic experiments supported a visible light-mediated radical-polar crossover dihydrothiolation process. This operationally straightforward reaction was also amenable to the synthesis of organometallic complexes, bis-sulfoxide ligand and a pleuromutilin antibiotic drug Tiamulin, which provided a practical route to synthesize highly valued compounds from the feedstock acetylene gas. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Recommanded Product: 2,2′-Oxybis(ethan-1-ol)).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: 2,2′-Oxybis(ethan-1-ol)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts