Category: 111-29-5

Quattrosoldi, Silvia published the artcileBio-based and one-day compostable poly(diethylene 2,5-furanoate) for sustainable flexible food packaging: Effect of ether-oxygen atom insertion on the final properties, Quality Control of 111-29-5, the publication is Chemosphere (2022), 291(Part_2), 132996, database is CAplus and MEDLINE.

In the present work, the effect of ether oxygen atom introduction in a furan ring-containing polymer has been evaluated. Solvent-free polycondensation process permitted the preparation of high mol. weight poly(diethylene 2,5-furandicarboxylate) (PDEF), by reacting the di-Me ester of 2,5-furandicarboxylic acid with diethylene glycol. After mol. and thermal characterization, PDEF mech. response and gas barrier properties to O₂ and CO₂, measured at different temperatures and humidity, were studied and compared with those of poly(butylene 2,5-furandicarboxylate) (PBF) and poly(pentamethylene 2,5-furanoate) (PPeF) previously determined Both PDEF and PPeF films were amorphous, differently from PBF one. As concerns mech. response, PDEF is more flexible than PBF but stiffer than PPeF. Moreover, PDEF is the most thermally stable (temperature of maximum degradation rate being 418 for PDEF, 407 for PBF and 414°C for PPeF) and hydrophilic (water contact angle being 74° for PDEF, 90° for PBF and 93° for PPeF), with gas barrier performances very similar to those of PPeF (O₂ and CO₂ transmission rate being 0.0022 and 0.0018 for PDEF and, 0.0016 and 0.0014 cm³ cm/m² d atm for PPeF). Lab scale composting experiments indicated that PDEF and PPeF were compostable, the former degrading faster, in just one day. The results obtained are explained on the basis of the high electronegativity of ether oxygen atom with respect to the carbon one, and the consequent increase of dipoles along the macromol.

Chemosphere published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Quality Control of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Forni, Jose A. published the artcileCarbonylative Hydroacylation of Styrenes with Alkyl Halides by Multiphoton Tandem Photoredox Catalysis in Flow, Name: Pentane-1,5-diol, the publication is ACS Catalysis (2022), 12(16), 10018-10027, database is CAplus.

The photocatalytic carbonylative hydroacylation of styrenes (R¹)R²C=CH₂ (R¹ = H, Ph, Me, Et; R² = Ph, naphthalen-2-yl, pyridin-2-yl, thiophen-2-yl, etc.) with inactivated alkyl halides RX (R = Cyclohexyl, cyclopentyl, n-Bu, i-Pr, etc.; X = Br, I) was reported. This protocol unifies the visible-light multiphoton catalytic cycle of [Ir(ppy)₂(dtb-bpy)]⁺ with flow chem. to engage energy-demanding alkyl bromides and iodides at moderate pressures of carbon monoxide. The mild and practical methodol. was employed to prepare a diverse array of 43 unsym. dialkyl ketones RC(O)CH₂CH(R¹)R² from primary, secondary, and tertiary inactivated alkyl halides. The application of flow chem. technol. to achieve spatially resolved chemoselectivity and broad functional group tolerance for the mild generation of functionalized C(sp³)-rich ketone products was demonstrated.

ACS Catalysis published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Name: Pentane-1,5-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Jeong, Jaeyoung published the artcileSelective Synthesis of Bisdimethylamine Derivatives from Diols and an Aqueous Solution of Dimethylamine through Iridium-Catalyzed Borrowing Hydrogen Pathway, Quality Control of 111-29-5, the publication is ChemCatChem (2022), 14(3), e202101499, database is CAplus.

A new system was developed for the selective synthesis of bisdimethylamine derivatives using a diol and dimethylamine as starting materials and an iridium complex bearing an N-heterocyclic carbene ligand as catalyst. The starting materials were easily available, less toxic, inexpensive and easy to handle. The reaction proceeded efficiently through a borrowing hydrogen pathway under aqueous conditions, without any addnl. organic solvent, to afford various bisdimethylamine derivatives in good to excellent yields.

ChemCatChem published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Quality Control of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lewandowska, Aneta published the artcileThiol-ene ionogels based on polymerizable imidazolium ionic liquids, Computed Properties of 111-29-5, the publication is Polymer Chemistry (2022), 13(21), 3154-3170, database is CAplus.

In this work, we report the synthesis of polymerizable ionic liquids (PILs) and the synthesis of ionogels by thiol-ene photopolymerization A series of gemini imidazolium-based bis(trifluoromethylsulfonyl)imide polymerizable ionic liquids with ene functional groups, reactive in thiol-ene polymerization, were synthesized. The obtained polymerizable ionic liquids differ by (i) type of reactive group: vinyl, allyl, (ii) length of hydrocarbon chain spacer (from C2 to C12) between two imidazole rings in cations in the vinyl series of PILs (divinyl-PIL), and (iii) type of substituent (-H or -CH₃) at C(2) position at the imidazole ring in diallyl-PILs. Then ionogel systems on the basis of the prepared PILs used as ene, 1,3,5-trimethylolpropane trimethacrylate (TMPTM), difunctional aliphatic polyester urethane acrylate (DAPU), and tris(3-mercaptobutyloxethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione (TMTT) were synthesized in 70 wt% of ionic liquid 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (EMImNTf₂). The mech. properties (tensile strength), ionic conductivity (electrochem. impedance spectroscopy), and thermal properties (differential scanning calorimetry, thermogravimetric anal.) of the prepared ionogels as well as the course of photopolymerization by the photo-DSC method were studied. The resulting ionogels are fully transparent, highly flexible, with no leakage (also at an elevated temperature 80 °C and during mech. testing), all thanks to the presence of PILs in the polymer matrix of ionogels. Interestingly, DSC studies have shown that the ionic liquid EMImNTf₂ does not crystallize in the synthesized ionogels in a broad range of temperatures (-170 – 30 °). The PIL structure influences the polymerization kinetics as well as properties of ionogels. All synthesized ionogels are stable in the temperature range 304 °C-325 °C, and ionogels with allyl-PILs have higher thermal stability than ionogels with vinyl-PILs. The strength (for the ionogels with PILs C2-C6) and Young′s modulus of the obtained ionogels increase with the length of the hydrocarbon chain of the spacer in vinyl-PILs but elongation and ionic conductivity decrease. However, the conductivity of ionogels is greater than 1 mS cm^-1, which allows the use of the obtained materials, e.g., in electrochem. capacitors.

Polymer Chemistry published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Computed Properties of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Haibin published the artcileColloidal self-assembly based all-metal metasurface absorbers to achieve broadband, polarization-independent light absorption at UV-Vis frequencies, HPLC of Formula: 111-29-5, the publication is Applied Surface Science (2022), 152624, database is CAplus.

Here, we demonstrate a straightforward colloidal self-assembly strategy to fabricate metasurface absorbers (MAs) with efficient broadband light absorption from UV to visible (Vis) spectral range. In this study, high-index faceted colloidal Au nanocrystals (NCs), i.e., Au icosidodecahedron with active surface plasmonic modes, are innovatively designed as the meta-atoms, while a facile electrostatic self-assembly progress is implemented to arrange these meta-atoms onto a gold reflecting film, resulting in MAs with all-metal structures. Optical characterizations show that the well-designed MAs with a 28-32% surface coverage of Au meta-atoms exhibit an average light absorption above 94% within the wavelengths ranging from 200 to 600 nm. Moreover, the particular absorption behaviors of the designed MAs are inherently polarization-independent for a broad range of incident angles (0-45°) owing to the ultrathin structure and topol. symmetry of the devices. It has been inferred that the pos. localized surface plasmon and gap plasmon resonances excited from the adjacent Au meta-atoms and gold film are critical for self-assembled MAs with excellent absorbing performances. Overall, this work provide an alternative and simple pathway for the construction of scalable and practical UV-Vis MAs, which may facilitate the high-frequency optical applications of thermophotovoltaics, photoelec. devices and photochem. systems.

Applied Surface Science published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C20H32B2O4, HPLC of Formula: 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Martins, Marcia S. published the artcileOccurrence of Allergens in Cosmetics for Sensitive Skin, Quality Control of 111-29-5, the publication is Cosmetics (2022), 9(2), 32, database is CAplus.

Sensitive skin is characterized by symptoms such as stinging and tingling in response to stimuli that usually do not cause unpleasant sensations. Epidemiol. studies show that individuals with sensitive skin are more prone to developing skin allergies, although the link between both conditions is unknown. Aiming to evaluate the presence of allergens in facial-skin products for sensitive skin, a pool of 88 cosmetic products from international brands marketed in pharmacies and parapharmacies was analyzed. A list of allergens identified in product labels was compiled and grouped according to their function. Fragrances were the most common allergens, followed by skin-conditioning agents, surfactants, and preservatives. Fragrances presenting the highest use percentages were linalool, benzyl alc., geraniol, and citronellol. Overall, the majority of cosmetic formulations were absent of fragrance allergens, being present only in 7% of products. Other allergens were found in most products (95%). This finding should be interpreted with caution, since many of these compounds are rare sensitizers and studies demonstrating their risk for individuals with sensitive skin are lacking. With this study, useful information for health professionals is provided to support their advice and to help consumers choosing cosmetic products.

Cosmetics published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Quality Control of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Manker, Lorenz P. published the artcileSustainable polyesters via direct functionalization of lignocellulosic sugars, Recommanded Product: Pentane-1,5-diol, the publication is Nature Chemistry, database is CAplus and MEDLINE.

The development of sustainable plastics from abundant renewable feedstocks was limited by the complexity and efficiency of their production, as well as their lack of competitive material properties. Here the authors demonstrate the direct transformation of the hemicellulosic fraction of nonedible biomass into a tricyclic diester plastic precursor at 83% yield (95% from com. xylose) during integrated plant fractionation with glyoxylic acid. Melt polycondensation of the resulting diester with a range of aliphatic diols led to amorphous polyesters (M_n = 30-60 kDa) with high glass transition temperatures (72-100°), tough mech. properties (ultimate tensile strengths of 63-77 MPa, tensile moduli of 2,000-2,500 MPa and elongations at break of 50-80%) and strong gas barriers (oxygen transmission rates (100 μm) of 11-24 cc m^-2 day^-1 bar^-1 and H₂O vapor transmission rates (100 μm) of 25-36 g m^-2 day^-1) that could be processed by injection molding, thermoforming, twin-screw extrusion and 3-dimensional printing. Although standardized biodegradation studies still need to be performed, the inherently degradable nature of facilitated their chem. recycling via methanolysis at 64°, and eventual depolymerization in room-temperature H₂O. [graphic not available: see fulltext].

Nature Chemistry published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Recommanded Product: Pentane-1,5-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chen, Tsun-Ren published the artcileIridium/graphene nanostructured catalyst for the N-alkylation of amines to synthesize nitrogen-containing derivatives and heterocyclic compounds in a green process, Formula: C5H12O2, the publication is RSC Advances (2022), 12(8), 4760-4770, database is CAplus and MEDLINE.

A facile iridium/graphene-catalyzed methodol. providing an efficient synthetic route for C-N bond formation is reported. This catalyst can directly promote the formation of C-N bonds, without pre-activation steps, and without solvents, alkalis and other additives. This protocol provides a direct N-alkylation of amines using a variety of primary and secondary alcs. with good selectivity and excellent yields. Charmingly, the use of diols resulted in intermol. cyclization of amines, and such products are privileged structures in biol. active compounds Two examples illustrate the advantages of this catalyst in organic synthesis: the tandem catalysis to synthesize hydroxyzine, and the intermol. cyclization to synthesize cyclizine. Water is the only byproduct, which makes this catalytic process sustainable and environmentally friendly.

RSC Advances published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Formula: C5H12O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Banoun, Camille published the artcileIntermolecular C-O Bond Formation with Alkoxyl Radicals: Photoredox-Catalyzed α-Alkoxylation of Carbonyl Compounds, Recommanded Product: Pentane-1,5-diol, the publication is Organic Letters (2021), 23(22), 8926-8930, database is CAplus and MEDLINE.

Due to the high reactivity of alkoxyl (RO·) radicals and their propensity to easily undergo β-scission or Hydrogen Atom Transfer (HAT) reactions, intermol. alkoxylations involving RO· radicals are barely described. Authors report herein for the first time the efficient intermol. trapping of alkoxyl radicals by silyl enol ethers. This photoredox-mediated protocol enables the introduction of both structurally simple and more complex alkoxy groups into a wide range of ketones and amides.

Organic Letters published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Recommanded Product: Pentane-1,5-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Klein, Victoria G. published the artcileAmide-to-Ester Substitution as a Strategy for Optimizing PROTAC Permeability and Cellular Activity, Application of Pentane-1,5-diol, the publication is Journal of Medicinal Chemistry (2021), 64(24), 18082-18101, database is CAplus and MEDLINE.

Criteria for predicting the druglike properties of “beyond Rule of 5” Proteolysis Targeting Chimeras (PROTAC) degraders are underdeveloped. PROTAC components are often combined via amide couplings due to their reliability. Amides, however, can give rise to poor absorption, distribution, metabolism, and excretion (ADME) properties. We hypothesized that a bioisosteric amide-to-ester substitution could lead to improvements in both physicochem. properties and bioactivity. Using model compounds, bearing either amides or esters, we identify parameters for optimal lipophilicity and permeability. We applied these learnings to design a set of novel amide-to-ester-substituted, VHL-based BET degraders with the goal to increase permeability. Our ester PROTACs retained intracellular stability, were overall more potent degraders than their amide counterparts, and showed an earlier onset of the hook effect. These enhancements were driven by greater cell permeability rather than improvements in ternary complex formation. This largely unexplored amide-to-ester substitution provides a simple strategy to enhance PROTAC permeability and bioactivity and may prove beneficial to other beyond Ro5 mols.

Journal of Medicinal Chemistry published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Application of Pentane-1,5-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts