Category: 111-29-5

Yu, Xiaowang published the artcilePolycondensation in confined nanopores toward the selective formation of narrowly dispersed linear polyesters, Related Products of alcohols-buliding-blocks, the publication is Polymer Chemistry (2022), 13(28), 4136-4143, database is CAplus.

The synthesis of linear polymers with both ends conserved is severely impeded due to the inevitable macrocyclization in step-growth polymerization (SGP). Indeed, macrocyclic polymers are considered as the ultimate destination of polycondensations for AB or A₂ + B₂ monomer combinations. Here, we present a new strategy to limit the macrocyclization process towards the selective formation of linear polyesters in the polycondensations of ω-hydroxyaliph. acid and the combinations of dicarboxylic acids and diols. By embedding the catalyst (sulfonic acid) in dendritic mesoporous silica nanoparticles (DMSNs), the polyesterifications were ushered to exclusively take place in the confined nanopores of DMSNs. The distribution of the α,ω-ends in different positions in the bundle of polyesters limited the end-to-end cyclization, leading to the selective chain extension especially in the high mol. weight region. NMR, GPC and MALDI-TOF results show that while the polyesters obtained in homogeneous polycondensation or with a nonporous heterogeneous catalyst were mainly with cyclic structures, the selective formation of linear polyesters was found in the confined nanopores of DMSNs. This finding contradicts the general sense that confined geometries are in favor of macrocyclization and provides a new understanding to manipulate the polymerization process towards the control of cyclic and linear topologies.

Polymer Chemistry published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C6H13NO2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Leong, Shi Xuan published the artcileNoninvasive and Point-of-Care Surface-Enhanced Raman Scattering (SERS)-Based Breathalyzer for Mass Screening of Coronavirus Disease 2019 (COVID-19) under 5 min, Synthetic Route of 111-29-5, the publication is ACS Nano (2022), 16(2), 2629-2639, database is CAplus and MEDLINE.

Population-wide surveillance of COVID-19 requires tests to be quick and accurate to minimize community transmissions. The detection of breath volatile organic compounds presents a promising option for COVID-19 surveillance but is currently limited by bulky instrumentation and inflexible anal. protocol. Here, we design a hand-held surface-enhanced Raman scattering-based breathalyzer to identify COVID-19 infected individuals in under 5 min, achieving >95% sensitivity and specificity across 501 participants regardless of their displayed symptoms. Our SERS-based breathalyzer harnesses key variations in vibrational fingerprints arising from interactions between breath metabolites and multiple mol. receptors to establish a robust partial least-squares discriminant anal. model for high throughput classifications. Crucially, spectral regions influencing classification show strong corroboration with reported potential COVID-19 breath biomarkers, both through experiment and in silico. Our strategy strives to spur the development of next-generation, noninvasive human breath diagnostic toolkits tailored for mass screening purposes.

ACS Nano published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Synthetic Route of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lu, Xiaojia published the artcileReductive Catalytic Depolymerization of Semi-industrial Wood-Based Lignin, SDS of cas: 111-29-5, the publication is Industrial & Engineering Chemistry Research (2021), 60(47), 16827-16838, database is CAplus and MEDLINE.

The current work studies the reductive catalytic depolymerization (RCD) of lignin from a novel semi-industrial process. The aim was to obtain aromatic mono-, di-, tri-, and tetramers for further valorization. The substrate and products were characterized by multiple anal. methods, including high pressure size-exclusion chromatog. (HPSEC), gas chromatog.-mass spectrometry, GC-flame ionization detector (FID), GC-FID/thermal conductivity detector (TCD), and NMR. The RCD was studied by exploring the influence of different parameters, such as lignin solubility, reaction time, hydrogen pressure, reaction temperature, pH, type and loading of the catalyst, as well as type and composition of the organic/aqueous solvent. The results show that an elevated temperature, a redox catalyst, and a hydrogen atm. are essential for the depolymerization and stability of the products, while the reaction medium also plays an important role. The highest obtained mono- to tetramers yield was 98% and mono- to dimers yield over 85% in the liquid phase products. The reaction mechanisms influenced the structure of the aliphatic chain in the monomers, but left the phenolic structure along with the methoxy groups largely unaltered. The current work contributes to the development and debottlenecking of the novel and sustainable overall process, which utilizes efficiently all the fractions of wood, in line with the principles of green engineering and chem.

Industrial & Engineering Chemistry Research published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, SDS of cas: 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Bai, Ping published the artcileDesign, Synthesis, and Evaluation of Thienodiazepine Derivatives as Positron Emission Tomography Imaging Probes for Bromodomain and Extra-Terminal Domain Family Proteins, Recommanded Product: Pentane-1,5-diol, the publication is Journal of Medicinal Chemistry (2021), 64(19), 14745-14756, database is CAplus and MEDLINE.

To better understand the role of bromodomain and extra-terminal domain (BET) proteins in epigenetic mechanisms, we developed a series of thienodiazepine-based derivatives and identified two compounds, 3a and 6a, as potent BET inhibitors. Further in vivo pharmacokinetic studies and anal. of in vitro metabolic stability of 6a revealed excellent brain penetration and reasonable metabolic stability. Compounds 3a and 6a were radiolabeled with fluorine-18 in two steps and utilized in positron emission tomog. (PET) imaging studies in mice. Preliminary PET imaging results demonstrated that [¹⁸F]3a and [¹⁸F]6a have good brain uptake (with maximum SUV = 1.7 and 2, resp.) and binding specificity in mice brains. These results show that [¹⁸F]6a is a potential PET radiotracer that could be applied to imaging BET proteins in the brain. Further optimization and improvement of the metabolic stability of [¹⁸F]6a are still needed in order to create optimal PET imaging probes of BET family members.

Journal of Medicinal Chemistry published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Recommanded Product: Pentane-1,5-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wongrakpanich, Amaraporn published the artcilePhyllanthus emblica extract-loaded transfersomes for hair follicle targeting: phytoconstituents, characterization, and hair growth promotion, COA of Formula: C5H12O2, the publication is Journal of Oleo Science (2022), 71(7), 1085-1096, database is CAplus and MEDLINE.

Phyllanthus emblica Linn. (PE) has been used to promote hair growth for decades. In this study, dried PE fruit powder was extracted, tested for biol. activities, and loaded into transfersomes for hair follicle targeting. Before lyophilization, PE fruit powder was extracted using 2 solvent systems, water and 30% ethanol. The PE 30% ethanolic extract had higher antioxidant activity and total phenolic content than the PE aqueous extract However, the cytotoxicity of the PE 30% ethanolic extract was higher than that of PE aqueous extract As a result, the PE aqueous extract was analyzed using ultra-performance liquid chromatog. and found that the major component of the PE aqueous extract was gallic acid. Afterward, the PE aqueous extract was tested for its potential to activate the expression of genes involved in hair growth promotion in human keratinocytes. At a non-toxic concentration (10 μg/mL), this extract promoted various growth factors comparable to 1% minoxidil. PE-loaded transfersomes were prepared to deliver the PE aqueous extract to the hair follicle. The particle size and polydispersity index of PE-loaded transfersomes were 228 nm and 0.25, resp. After 3 mo of storage, the particle size at 4°C and 30°C was 218 nm and 241 nm, resp., which was comparable to its initial size. However, at 40°C, the particle size dramatically increased (315 nm). The fluorescent agent, rhodamine B, was used to evaluate the potential of transfersomes to target hair follicles. Rhodamine B transfersomes had better penetration and accumulation in hair follicles than rhodamine B solution To conclude, the PE aqueous extract, mainly composed of gallic acid, can activate hair growth gene expression. The extract can be loaded into hair follicles targeting transfersomes. Thus, PE-loaded transfersomes are a promising delivery system for hair follicle targeting to promote hair growth.

Journal of Oleo Science published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H6N2O2, COA of Formula: C5H12O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ziegler, Felix published the artcileConfinement Effects for Efficient Macrocyclization Reactions with Supported Cationic Molybdenum Imido Alkylidene N-Heterocyclic Carbene Complexes, Synthetic Route of 111-29-5, the publication is ACS Catalysis (2021), 11(18), 11570-11578, database is CAplus.

For entropic reasons, the synthesis of macrocycles via olefin ring-closing metathesis (RCM) is impeded by competing acyclic diene metathesis (ADMET) oligomerization. With cationic molybdenum imido alkylidene N-heterocyclic carbene (NHC) complexes confined in tailored ordered mesoporous silica, RCM can be run with macrocyclization selectivities up to 98% and high substrate concentrations up to 0.1 M. Mol. dynamics simulations show that the high conversions are a direct result of the proximity between the surface-bound catalyst, proven by extended X-ray absorption spectroscopy, and the surface-located substrates. Back-diffusion of the macrocycles decreases with decreasing pore diameter of the silica and is responsible for the high macrocyclization efficiency. Also, Z-selectivity increases with decreasing pore diameter and increasing Tolman electronic parameter of the NHC. Running reactions at different concentrations allows for identifying the optimum substrate concentration for each material and substrate combination.

ACS Catalysis published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C8H17Br, Synthetic Route of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Upare, Pravin P. published the artcileA Bimetallic Ru₃Sn₇ Nanoalloy on ZnO Catalyst for Selective Conversion of Biomass-Derived Furfural into 1,2-Pentanediol, Related Products of alcohols-buliding-blocks, the publication is ACS Sustainable Chemistry & Engineering (2021), 9(51), 17242-17253, database is CAplus.

Chemoselective hydrogenolysis of biomass-derived feedstocks into chems. is one of the most challenging transformations for upgrading biomass over noble-metal-based heterogeneous catalysts. Here, we demonstrate the use of an efficient Ru₃Sn₇ alloy-supported ZnO catalyst (Ru-Sn/ZnO) to convert biomass-derived furfural (FF) by selective formation of 1,2-pentanediol (1,2-PDO). We found that 1,2-PDO can be produced with a very high yield (>84%) while limiting the competitive formation of 1,5-PDO (yield of âˆ?2%) and other side hydrogenation reactions during FF hydrogenolysis. The new catalyst showed excellent catalytic performance and catalyst reusability when tested for up to five consecutive cycles without any significant deactivation. The remarkable performance of Ru-Sn/ZnO for selective formation of 1,2-PDO from FF was attributed to the combined effect of Ru₃Sn₇ alloy phases together with tin oxide species on a basic ZnO support. All the tested catalysts were thoroughly characterized through different characterization techniques to confirm the synergy of the active sites in the Ru-Sn/ZnO combination and its effectiveness for selective formation of 1,2-PDO. In addition, a possible reaction mechanism is proposed based on d. functional theory calculations and their correlation with exptl. results.

ACS Sustainable Chemistry & Engineering published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C4H6N2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ali, Barkat published the artcileImpact of Soy-Cow’s mixed milk enzyme modified cheese on bread aroma, Synthetic Route of 111-29-5, the publication is LWT–Food Science and Technology (2022), 112793, database is CAplus.

The effect of spray-dried Soy-Cow’s mixed milk enzyme modified (SC-EM) cheese on wheat dough properties and bread aroma was evaluated at either 0.1, 0.5, 1.0, 1.5 or 2.0% (weight/weight). Significant accumulation of amino acids and peptides of dough were noted as SC-EM cheese levels increased. After baking a total of 118 volatile compounds (VCs) were identified in breads having aldehydes, alcs., esters and acids in major proportions. Higher contents of Maillard product 3-hydroxy-2-butanone, 2-methyl-1-propanol, phenylethyl alc., undecane, L-limonene, 2-pentyl furan and lipid oxidation compounds hexanoic acid Et ester, octanoic acid Et ester, decanoic acid Et ester, butanoic acid, hexanoic acid and octanoic acid were observed Isoamyl alc., lactic acid Et ester, Et sorbate and sorbic acid were the newly identified VCs. These results revealed that SC-EM cheese could be used as improver in dough and contribution to bread aroma. Thus, SC-EM cheese has been proposed to be included in fortified bakery products.

LWT–Food Science and Technology published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Synthetic Route of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Soeta, Takahiro published the artcileN-Heterocyclic Carbene-Catalyzed Chemoselective Monoacylation of 1,n-Linear Diols, Application In Synthesis of 111-29-5, the publication is Organic Letters (2021), 23(21), 8138-8142, database is CAplus and MEDLINE.

This paper discusses the N-heterocyclic carbene (NHC)-catalyzed redox monoacylation of 1,n-linear diols using α-benzoyloxyaldehydes. The reactions afforded monoacylated diols in moderate to good selectivities and chem. yields. Authors original NHC bearing a pyridine moiety plays an important role in achieving good chemoselectivities. A wide range of 1,n-linear diols were successfully applied to this reaction.

Organic Letters published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C12H16O3, Application In Synthesis of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Agrawal, Aparna published the artcileFabrication and Characterization of Re-Entrant Honeycomb Polyurethane Aerogels, Name: Pentane-1,5-diol, the publication is ACS Applied Polymer Materials (2022), 4(5), 3791-3801, database is CAplus.

In this work, polyurethane aerogels are fabricated in re-entrant honeycomb forms to achieve auxeticity and much higher flexibility than corresponding aerogel monoliths. For this purpose, a set of re-entrant honeycomb-shaped hollow molds is first printed from high-impact polystyrene (HIPS) using a fused filament fabrication technique and subsequently filled with polyurethane sol synthesized from an aliphatic triisocyanate and a diol selected from among butanediol, pentanediol, hexanediol, or octanediol. A sol-gel transition process yields the gel in a re-entrant honeycomb shape, which is isolated by dissolving the HIPS mold and supercritically dried using carbon dioxide. The effects of diol chain length on the properties of aerogels, such as bulk d., pore size, and tensile properties are investigated. The auxetic aerogels show different deformation behavior and much higher elongation at break than dog bone-shaped aerogel monoliths. Such unique properties of auxetic structures can extend applications of aerogels as acoustic absorbers and smart bandages that require high porosity, tunable pore structures, and high flexibility.

ACS Applied Polymer Materials published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Name: Pentane-1,5-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts