Category: 111-29-5

Li, Yanrui published the artcileThermodynamic parameters and infinite dilution activity coefficients for organic solutes in deep eutectic solvent: Choline Chloride + 1,5-Pentanediol, HPLC of Formula: 111-29-5, the publication is Journal of Chemical Thermodynamics (2022), 106784, database is CAplus.

A series of thermodn. parameters related to choline chloride + 1,5-pentanediol deep eutectic solvent were studied through inverse gas chromatog. at 303.15-343.15 K. The infinite dilution activity coefficient (γ∞12) was used to predict the solute separation ability and the intermol. interaction strength of DES. The interaction between mols. was further described by partial molar excess properties (ΔH^E,∞₁,TΔS^E,∞₁, ΔG^E,∞₁). The value of γ∞12 was also used to compute the separation parameters for common separation problems benzene (1)/methanol (2), n-hexane (1)/benzene (2) and benzene (1)/thiophene (2). The miscibility of organic solutes and DES was evaluated using the Flory-Huggins interaction parameter, and the result showed alcs. were good solvents for the DES. Moreover, the Hildebrand solubility parameters (I₂) of the DES were calculated, and the result revealed that the value showed a downward trend with the increase of temperature

Journal of Chemical Thermodynamics published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, HPLC of Formula: 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Zhuangqing published the artcileSelective hydrogenolysis of tetrahydrofurfuryl alcohol to 1,5-pentanediol over PrO_x promoted Ni catalysts, SDS of cas: 111-29-5, the publication is Catalysis Today (2022), 79-87, database is CAplus.

Catalytic conversion of furfural and its derivatives to value-added C₅ mols. has attractive much attention in the field of biomass conversion. In this paper, the selective hydrogenolysis of tetrahydrofurfuryl alc. to 1,5-pentanediol has been studied over a series of PrO_x promoted Ni/Al₂O₃ catalysts. The catalytic performances and the promoting effects of PrO_x, as well as the role of Ni and PrO_x species have been discussed. The surface properties and structure of catalysts were examined by TEM, XRD, XPS, H₂-TPR, H₂-TPD, in-situ DRIFTS, etc. The presence of PrO_x species promotes the reaction rate and changes product selectivity significantly, and a 79.2% 1,5-pentanediol selectivity can be obtained at 88.4% conversion over the NiPr_1.2/Al₂O₃ catalyst. The synergistic effect between defect-rich PrO_x and the adjacent active Ni species has been confirmed to contribute to the superior catalytic performances. These results provide useful knowledge for the activation of cyclic ether bonds and the design of heterogeneous catalysts with lanthanide oxide supports.

Catalysis Today published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C9H6FNO, SDS of cas: 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Shuo published the artcileStructure-activity relationship study of dihydroartemisinin C-10 hemiacetal derivatives as Toll-like receptor 4 antagonists, Formula: C5H12O2, the publication is Bioorganic Chemistry (2021), 105107, database is CAplus and MEDLINE.

Dihydroartemisinin (DHA), a natural product isolated from the traditional Chinese herb Artemisia annua and one of the clin. frontline drugs against malarial infections, has recently been discovered as a Toll-like Receptor 4 (TLR4) antagonist. However, the TLR4 antagonistic activity of DHA is modest and it exhibits cellular toxicity. In this work, the structure-activity relationship (SAR) of DHA as TLR4 antagonist was explored. Since destroying the sesquiterpene endoperoxide scaffold substantially compromised the TLR4 antagonistic activity and mol. dynamics anal. showed that the C-10 hydroxyl group formed a hydrogen bond with E72 of myeloid differentiation factor 2 (MD2) to prevent it moving deeper into MD2, SAR of DHA was focused on the C-10 hemiacetal position. With extending the length of the linear alkane chain at C10 position, the TLR4 antagonistic activity of DHA analogs increased first and then decreased with the best TLR4 antagonism occurring at the length of the carbon chain of 3-4 carbons. In contrast, the cellular toxicity of DHA analogs was raised with the increasing length of the linear alkane chain. The TLR4 antagonistic activity of DHA derivatives with substituted halogen as the terminal functional group decreased with the decrease of electronegativity of the substituted halogen, which implies the electron-rich functional group at the end of the alkane chain appears preferred. Therefore, DHA derivative 2k with alkynyl as the end functional group, exhibited 14 times more potent TLR4 antagonistic activity than DHA. Moreover, 2k showed less cellular toxicity than DHA. Cellular signaling characterizations indicated that 2k inhibited LPS-induced TLR4 dimerization and endocytosis and suppressed LPS-induced NF-κB but not MAPKs activation, culminating in blocking LPS-induced TLR4 signaling downstream pro-inflammatory factors NO and IL-1β. Further, 2k was active in vivo; it significantly increased and prolonged morphine analgesia. Collectively, this study provides a structural guidance to reposition DHA derivatives as TLR4 antagonists.

Bioorganic Chemistry published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C12H20O6, Formula: C5H12O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ho, Angel published the artcileAcid-Catalyzed Intramolecular Ring-Opening Reactions of Cyclopropanated Oxabenzonorbornadienes with Carboxylic Acid Nucleophiles, Related Products of alcohols-buliding-blocks, the publication is Synthesis (2022), 54(5), 1422-1430, database is CAplus.

The present work demonstrates the ability of carboxylic acid tethered cyclopropanated oxabenzonorbornadienes (CPOBDs) to undergo ring-opening reactions in mild acidic conditions. The optimized reaction conditions involve the use of pTsOH in DCE at 90°C. Two regioisomers are formed but the reactions are highly regioselective towards type 3 ring-opened products. It was observed that substitution at the C5 and aryl positions of CPOBD significantly hinders the ring-opening reactions leading to decreased yields of ring-opened products, although high regioselectivity for the Type 3 ring-opened products is still maintained. Herein, the first examples of acid-catalyzed intramol. ring-opening reactions of CPOBD with carboxylic acid nucleophiles are reported.

Synthesis published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Xinsheng published the artcileCatalytic Conversion of Tetrahydrofurfuryl Alcohol over Stable Pt/MoS₂ Catalysts, Application In Synthesis of 111-29-5, the publication is Catalysis Letters (2021), 151(9), 2734-2747, database is CAplus.

MoS₂ supported noble metal catalysts were used for the catalytic conversion of terahydrofurfuryl alc. (THFA) to 1,5-pentanediol (1,5-PDO) and its derivate tetrahydropyrane (THP). Over the optimal 4%Pt/MoS₂-FR catalyst, 75.8% overall selectivity (35.4% to 1,5-PDO and 40.4% to THP) and 63.7% conversion of 5 wt% THFA solution were obtained after 8 h reaction at 250°C. The catalyst showed stable catalytic performance in five-cycle reactions, demonstrating the robustness of Pt/MoS₂ under the harsh hydrothermal and hydrogenation conditions. A variety of characterizations, including CO-DRIFTS, HRTEM, H₂-TPR, Raman spectroscopy and XPS revealed that typical behavior of strong metal-support interaction (SMSI) existed between Pt and MoS₂, largely caused by the coverage of MoS₂ over Pt and rarely reported previously. The Pt/MoS₂ had intact structure under the harsh conditions thanks to the SMSI and chem. stability of MoS₂. The acidity of Pt/MoS₂ was negligible, and the active sites for the reaction were attributed to Pt and the Mo sites interacting closely on the catalysts. The reaction pathway was proposed according to the product distributions and the results of conditional experiments

Catalysis Letters published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Application In Synthesis of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wolosz, Dominik published the artcileEnvironmentally Friendly Synthesis of Urea-Free Poly(carbonate-urethane) Elastomers, COA of Formula: C5H12O2, the publication is Macromolecules (Washington, DC, United States) (2022), 55(12), 4995-5008, database is CAplus.

This work presents an eco-friendly synthetic pathway toward non-isocyanate poly(carbonate-urethane)s (NIPCUs) obtained from carbon dioxide and its simple derivatives-organic carbonates. Bis(hydroxyalkyl carbamate)s synthesized from ethylene carbonate and appropriate α,ω-diamines were used as polyurethane hard segment precursors while oligocarbonate diols as soft segment ones. The structures and properties of the obtained NIPCUs were explored by means of ¹H NMR, ¹³C NMR, and FT-IR spectroscopies, MALDI-ToF mass spectrometry, DSC, and mech. testing. Based on spectroscopic data as well as model reactions, it was demonstrated that the formation of the urea bonds was suppressed due to the presence of carbonate moieties. The reaction of urea bonds with carbonate residues led to urethane group formation. In addition, the influence of the polyurethane structure on the mech. and thermal properties of the obtained polymers was studied. The obtained NIPCUs exhibited mech. properties comparable to conventional polyurethane elastomers (e.g., a tensile strength of 32 MPa and an elongation at break of 800%). The described synthetic route is an straightforward way toward the replacement of conventional polyurethanes with environmentally friendly ones.

Macromolecules (Washington, DC, United States) published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C7H13BrSi, COA of Formula: C5H12O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Huang, Jin published the artcileSimple Approach to Macrocyclic Carbonates with Fast Polymerization Rates and Their Polymer-to-Monomer Regeneration, HPLC of Formula: 111-29-5, the publication is Macromolecules (Washington, DC, United States) (2022), 55(2), 608-614, database is CAplus.

Designing polymeric materials for closed-loop material streams is the key to achieving a circular society. Here, a library of macrocyclic carbonates (MCs) was designed by a facile and direct one-pot, two-step synthesis approach without the use of a solvent at a 10 g scale. We demonstrate that anionic polymerization with tert-butoxide enables the ultrafast ring-opening polymerization (ROP) of MCs with high conversion (>97%) within seconds (3-10 s) at ambient temperature The polymerization rate depends on the odd or even number of methylene groups between the carbonate linkages in the MCs, and not the overall ring size, yielding an “odd-even” effect. This polymerization rate is related to the difference in mol. conformation of the MCs, as determined by X-ray crystallog. The polymers (polypenta-, hexa-, heptamethylene carbonate) were subsequently regenerated back to their original MCs at a high selectivity (95-99 mol %) and good yields (70-85%), hence taking a step toward closing the loop on these long alkyl chain polycarbonates.

Macromolecules (Washington, DC, United States) published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, HPLC of Formula: 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Halloran, Matthew W. published the artcileSmall molecule plasticizers for improved migration resistance: Investigation of branching and leaching behaviour in PVC blends, Synthetic Route of 111-29-5, the publication is Materials Today Communications (2021), 102874, database is CAplus.

The influence of branching on plasticizer effectiveness and migration behavior of heptyl-succinate plasticizers blended with poly(vinyl chloride) (PVC) was evaluated. An increase of branching led to a decrease in migration of the plasticizers into both hexanes and vegetable oil medias. Addnl., a quant. ¹H NMR method was used to identify plasticizer concentration in the leachates and compared to a gravimetric standard test method. Overall, the quant. ¹H NMR method proved to be a more direct method to assess leaching. In comparison to com. plasticizer di(2-ethylhexyl) phthalate (DEHP) and alternative plasticizer diheptyl succinate (DHPS), all of the branched species displayed superior migration resistance into hexanes (two to ten-fold). The glass transition temperatures and stress at break data indicated that the plasticizers comprised of up to three branches functioned as well as, or better than DEHP and DHPS. However, there was a decrease in plasticizer efficiency with compounds comprised of four or more branches.

Materials Today Communications published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Synthetic Route of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Albozahid, Muayad published the artcileEnhanced mechanical, crystallisation and thermal properties of graphene flake-filled polyurethane nanocomposites: the impact of thermal treatment on the resulting microphase-separated structure, Quality Control of 111-29-5, the publication is Journal of Polymer Research (2021), 28(8), 302, database is CAplus.

The present work investigates the combined effect of the addition of graphite nanoplatelets (xGNPs) to polyurethane copolymer (PUC) and thermal treatment was employed. The PUC reinforced by xGNP were synthesized by in-situ polymerization, which leads to an effective performance of the PUC/xGNP system. Meanwhile, X-ray diffraction and Raman spectroscopy tests displayed the inter-spacing planar quality of xGNP nanofillers. The thermal stability of PUC was seen to increase with addition of xGNP. Addnl., the dynamic storage modulus (E’) showed better performance after thermal treatment than in the untreated samples. However, a relationship between the microphase-separated morphol. of PUC induced by thermal treatment and the addition of xGNP has been observed Consequently, the crystallinity percentage increased after thermal treatment @ 80 C for 4 days, presuming a re-ordering of amorphous hard segments during the heating in a packed microphase conformation. On the other hand, better dispersion and interaction of xGNP can play a crucial role in enhancing the thermal and mech. properties, and thus a significant reinforcement for PUC. The tensile properties such as modulus and tensile strength showed significant enhancement with xGNP incorporation, while the elongation steeply dropped. On the contrary, a deterioration in modulus and tensile strength resulted from thermal treatment, likely due to the restacking of xGNP during segmental movement and thus increasing the amorphous phase rather than the crystalline phase. A modified Halpin-Tsai model was utilized to predict the mismatch between the empirical and theor. results. Consequently, the findings displayed the divergence of the nanocomposite modulus of PUC with greater amounts of xGNP nanofillers.

Journal of Polymer Research published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Quality Control of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Albozahid, Muayad published the artcileEffect of OMMT reinforcement on morphology and rheology properties of polyurethane copolymer nanocomposites, Related Products of alcohols-buliding-blocks, the publication is Journal of Elastomers & Plastics (2021), 53(8), 992-1014, database is CAplus.

The remarkable structural features of organic modified montmorillonite particles (OMMT) enable them to complete their important role in enhancing different properties of polyurethane copolymer with 75 weight% hard segments (PUC/75). Based on the melt intercalation approach, various amounts of OMMT were incorporated into PUC/75 solution followed by the injection molding process. It is essential to mention that the synthesized PUC/75 in this work relied on using 1,5-Pentanediol as a chain extender in order to produce a long-term and thermal-stable PUC successfully. The effect of incorporating various loading of OMMT on rheol. properties of neat PUC/75 and its nanocomposites was investigated. The structure of PUC/OMMT was studied using X-ray diffraction (XRD) and SEM. Addnl., differential scanning calorimetry (DSC) thermograms were utilized to investigate OMMT effect on the thermal transitions and crystallinity of resultant PUC nanocomposites. Interestingly, the dynamic rheol. anal. exhibited a remarkable increase in melt rheol. behavior with increasing OMMT loading compared to neat PUC/75. This could imply a good interaction between the functional group on the surface of OMMT and PUC/75 domains; particularly hard domains, herein the DSC results showed moderate improvement in melt temperature (T_m) of PUC/OMMT nanocomposite. However, a decline in crystalline temperature (T_c) was also seen due to aggregation of OMMT, especially at higher OMMT loading. While XRD results exhibited a slight shifting in crystalline peaks of PUC nanocomposites relative to neat PUC/75.

Journal of Elastomers & Plastics published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts