Category: 111-29-5

On May 1, 2020, Behera, Rakesh R.; Ghosh, Rahul; Panda, Surajit; Khamari, Subrat; Bagh, Bidraha published an article.Name: Pentane-1,5-diol The title of the article was Hydrosilylation of Esters Catalyzed by Bisphosphine Manganese(I) Complex: Selective Transformation of Esters to Alcohols. And the article contained the following:

A tricarbonylruthenium Xantphos complex I was prepared and characterized by X-ray crystallog.; in the presence of I, esters underwent chemoselective hydrosilylation with phenylsilane under neat conditions (followed by workup with base) to yield esters. Aryl, alkyl, and alkenyl mono- and dicarboxylates and lactones underwent chemoselective reduction to alcs. and diols; ketoesters underwent reduction to diols. Poly(1,6-hexanediol adipate) underwent hydrosilylation to 1,6-hexanediol. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Name: Pentane-1,5-diol

The Article related to alc diol preparation, xantphos manganese complex preparation chemoselective hydrosilylation catalyst crystal structure, manganese catalyst chemoselective hydrosilylation ester and other aspects.Name: Pentane-1,5-diol

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On October 31, 2021, Van de Voorde, Babs; Benmeridja, Lara; Giol, Elena Diana; Van der Meeren, Louis; Van Damme, Lana; Liu, Zhen; Toncheva, Antoniya; Raquez, Jean-Marie; Van den Brande, Niko; Skirtach, Andre; Declercq, Heidi; Dubruel, Peter; Van Vlierberghe, Sandra published an article.Recommanded Product: Pentane-1,5-diol The title of the article was Potential of poly(alkylene terephthalate)s to control endothelial cell adhesion and viability. And the article contained the following:

Poly(ethylene terephthalate) (PET) is known for its various useful characteristics, including its applicability in cardiovascular applications, more precisely as synthetic bypass grafts for large diameter (≥ 6 mm) blood vessels. Although it is widely used, PET is not an optimal material as it is not interactive with endothelial cells, which is required for bypasses to form a complete endothelium. Therefore, in this study, poly(alkylene terephthalate)s (PATs) have been studied. They were synthesized via a single-step solution polycondensation reaction, which requires mild reaction conditions and avoids the use of a catalyst or additives like heat stabilizers. A homologous series was realized in which the alkyl chain length varied from 5 to 12 methylene groups (n = 5-12). Molar masses up to 28,000 g/mol were obtained, while various odd-even trends were observed with modulated differential scanning calorimetry (mDSC) and rapid heat-cool calorimetry (RHC) to access the thermal properties within the homologous series. The synthesized PATs have been subjected to in vitro cell viability assays using Human Umbilical Vein Endothelial Cells (HUVECs) and Human Dermal Microvascular Endothelial Cells (HDMECs). The results showed that HUVECs adhere and proliferate most pronounced onto PAT(n = 9) surfaces, which could be attributed to the surface roughness and morphol. as determined by at. force microscopy (AFM) (i.e. Rq = 204.7 nm). HDMECs were investigated in the context of small diameter vessels and showed superior adhesion and proliferation after seeding onto PAT(n = 6) substrates. These preliminary results already pave the way towards the use of PAT materials as substrates to support endothelial cell adhesion and growth. Indeed, as superior endothelial cell interactivity compared to PET was observed, time-consuming and costly surface modifications of PET grafts could be avoided by exploiting this novel material class. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Recommanded Product: Pentane-1,5-diol

The Article related to polyalkylene terephthalate endothelial cell adhesion viability, endothelial cell adhesion, poly(alkylene terephthalate), solution polycondensation, synthetic bypass graft and other aspects.Recommanded Product: Pentane-1,5-diol

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On January 31, 2022, Corazza, Monica; Schenetti, Cecilia; Schettini, Natale; Zedde, Pierantonia; Borghi, Alessandro published an article.Quality Control of Pentane-1,5-diol The title of the article was Pentylene glycol: An emerging cosmetic allergen?. And the article contained the following:

A review. In this report patch tests with pentylene glycol (PTG) and propylene glycol (PG) at the same concentrations were performed in 15 healthy subjects with no reactions. Pentylene glycol is a preservative, solvent, and humectant that might be used increasingly in cosmetic products. It is considered to be both a weak irritant and a weak allergen. In our patient no cross reactions were observed, confirming what has been observed in the literature. Further studies are strongly needed define the real allergenic potential of this mol., which is used frequently in cosmetics that are formulated for sensitive and atopic skin. Finally, the occurrence of cross reactivity between different glycols should be deeply investigated, perhaps using higher patch-test concentrations and later readings. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Quality Control of Pentane-1,5-diol

The Article related to review pentylene glycol cosmetic allergen irritant patch test, 1,5-pentanediol, cas no 5343-92-0, allergic contact dermatitis, case report, cosmetic cream, glycols, pentylene glycol and other aspects.Quality Control of Pentane-1,5-diol

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On January 15, 2021, Cen, Xuecong; Liu, Yu; Chen, Bo; Liu, Dehua; Chen, Zhen published an article.Category: alcohols-buliding-blocks The title of the article was Metabolic engineering of Escherichia coli for de novo production of 1,5-pentanediol from glucose. And the article contained the following:

1,5-Pentanediol (1,5-PDO) is an important C5 building block for the synthesis of different value-added polyurethanes and polyesters. However, no natural metabolic pathway exists for the biosynthesis of 1,5-PDO. Herein we designed and constructed a promising nonnatural pathway for de novo production of 1,5-PDO from cheap carbohydrates. This biosynthesis route expands natural lysine pathways and employs two artificial metabolic modules to sequentially convert lysine into 5-hydroxyvalerate (5-HV) and 1,5-PDO via 5-hydroxyvaleryl-CoA. Theor., the 5-hydroxyvaleryl-CoA-based pathway is more energy-efficient than a recently published carboxylic acid reductase-based pathway for 1,5-PDO production By combining strategies of systematic enzyme screening, pathway balancing, and transporter engineering, we successfully constructed a minimally engineered Escherichia coli strain capable of producing 3.19 g/L of 5-HV and 0.35 g/L of 1,5-PDO in a medium containing 20 g/L of glucose and 5 g/L lysine. Introducing the synthetic modules into a lysine producer and enhancing NADPH supply enabled the strain to accumulate 1.04 g/L of 5-HV and 0.12 g/L of 1,5-PDO using glucose as the main carbon source. This work lays the basis for the development of a biol. route for 1,5-PDO production from renewable bioresources. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Category: alcohols-buliding-blocks

The Article related to metabolic engineering escherichia pentanediol glucose anaerobic fermentation, 1,5-pentanediol, escherichia coli, enzyme screening, lysine, metabolic engineering, nonnatural pathway and other aspects.Category: alcohols-buliding-blocks

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Alcohol – Wikipedia,
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Vieira, Vanessa; Calhelha, Ricardo C.; Barros, Lillian; Coutinho, Joao A. P.; Ferreira, Isabel C. F. R.; Ferreira, Olga published an article in 2020, the title of the article was Insights on the extraction performance of alkanediols and glycerol: using Juglans regia L. leaves as a source of bioactive compounds.Recommanded Product: 111-29-5 And the article contains the following content:

Glycerol and alkanediols are being studied as alternative solvents to extract phytochems. from plant material, often as hydrogen bond donors in deep eutectic solvents (DESs). Many of those alcs. are liquid at room temperature, yet studies of their use as extraction solvents are scarce. In this work, glycerol and a series of alkanediols (1,2-ethanediol, 1,2-propanediol, 1,3-propanediol, 1,3-butanediol, 1,2-pentanediol, 1,5-pentanediol, and 1,2-hexanediol) were studied for the extraction of phenolic compounds from Juglans regia L. leaves, a rich source of this class of bioactive compounds The extraction yield was quantified, and the bioactivity of both extracts and pure solvents was evaluated by measuring the anti-inflammatory and cytotoxic activities. The solvents showing the best combined results were 1,2 and 1,3-propanediol, as their extracts presented a high amount of phenolic compounds, close to the results of ethanol, and similar cytotoxicity against cervical carcinoma cells, with no impact on non-tumor porcine liver cells in the studied concentration range. On the other hand, none of the extracts (and solvents) presented anti-inflammatory activity. Overall, the results obtained in this work contribute to the study of alternative solvents that could potentially be used also as formulation media, highlighting the importance of walnut leaves as a source of bioactive compounds The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Recommanded Product: 111-29-5

The Article related to juglans leaf phenolic compound extraction alkanediols glycerol hplc, juglans regia l., alkanediols, anti-inflammatory activity, cytotoxicity, glycerol, phenolic compounds, solvents and other aspects.Recommanded Product: 111-29-5

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Alcohol – Wikipedia,
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Wongrakpanich, Amaraporn; Leanpolchareanchai, Jiraporn; Morakul, Boontida; Parichatikanond, Warisara; Teeranachaideekul, Veerawat published an article in 2022, the title of the article was Phyllanthus emblica extract-loaded transfersomes for hair follicle targeting: phytoconstituents, characterization, and hair growth promotion.Product Details of 111-29-5 And the article contains the following content:

Phyllanthus emblica Linn. (PE) has been used to promote hair growth for decades. In this study, dried PE fruit powder was extracted, tested for biol. activities, and loaded into transfersomes for hair follicle targeting. Before lyophilization, PE fruit powder was extracted using 2 solvent systems, water and 30% ethanol. The PE 30% ethanolic extract had higher antioxidant activity and total phenolic content than the PE aqueous extract However, the cytotoxicity of the PE 30% ethanolic extract was higher than that of PE aqueous extract As a result, the PE aqueous extract was analyzed using ultra-performance liquid chromatog. and found that the major component of the PE aqueous extract was gallic acid. Afterward, the PE aqueous extract was tested for its potential to activate the expression of genes involved in hair growth promotion in human keratinocytes. At a non-toxic concentration (10 μg/mL), this extract promoted various growth factors comparable to 1% minoxidil. PE-loaded transfersomes were prepared to deliver the PE aqueous extract to the hair follicle. The particle size and polydispersity index of PE-loaded transfersomes were 228 nm and 0.25, resp. After 3 mo of storage, the particle size at 4°C and 30°C was 218 nm and 241 nm, resp., which was comparable to its initial size. However, at 40°C, the particle size dramatically increased (315 nm). The fluorescent agent, rhodamine B, was used to evaluate the potential of transfersomes to target hair follicles. Rhodamine B transfersomes had better penetration and accumulation in hair follicles than rhodamine B solution To conclude, the PE aqueous extract, mainly composed of gallic acid, can activate hair growth gene expression. The extract can be loaded into hair follicles targeting transfersomes. Thus, PE-loaded transfersomes are a promising delivery system for hair follicle targeting to promote hair growth. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Product Details of 111-29-5

The Article related to phyllanthus emblica extract transfersome hair follicle phytoconstituent growth promotion, phyllanthus emblica , follicle targeting, hair growth promoter, stability, transfersomes and other aspects.Product Details of 111-29-5

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On August 30, 2020, Abid, Mehwish; Naveed, Muhammad; Azeem, Iqra; Faisal, Amir; Faizan Nazar, Muhammad; Yameen, Basit published an article.Computed Properties of 111-29-5 The title of the article was Colon specific enzyme responsive oligoester crosslinked dextran nanoparticles for controlled release of 5-fluorouracil. And the article contained the following:

Targeting bioactives selectively to diseased sites is one of the most challenging aspects of cancer therapy. Herein, fabrication of colonic enzyme-responsive dextran based oligoester crosslinked nanoparticles is reported for the controlled release of 5-fluorouracil (5-FU) – an anticancer drug. The 5-FU drug loaded nanoparticles (DNPs, size ∼237 ± 25 nm, ζ-potential -17.0 ± 3 mV) were developed by the in-situ crosslinking of dextran with a bifunctional telechelic oligoester followed by the phys. drug encapsulation via nanopptn. Drug encapsulation efficiency and drug loading capacity of DNPs were found to be ∼76% (±0.1) and ∼8% (±0.1), resp. The DNPs were demonstrated to release the encapsulated drug selectively in the presence of dextranase enzyme. The in vitro release kinetics assay revealed that the DNPs released about 75% (±4) of the entrapped drug within 12 h of incubation with dextranase enzyme. No drug was released in a control experiment where DNPs were exposed to pH conditions encountered in the stomach and small intestine. Moreover, the treatment of HCT116 colon cancer cell line with the developed DNPs highlighted its biocompatibility as well as dextranase triggered cytotoxicity. The developed system offers an avenue to reduce the non-specific cytotoxicity of the encapsulated 5-FU, and a colon specific delivery of the encapsulated drug in response to the dextranase enzyme. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Computed Properties of 111-29-5

The Article related to colon responsive oligoester crosslinked dextran nanoparticle fluorouracil, 5-fluorouracil, crosslinked dextran nanoparticles, dextranase responsive delivery system, telechelic oligoester and other aspects.Computed Properties of 111-29-5

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Alcohol – Wikipedia,
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On November 9, 2020, Lee, Yih Hong; Shi, Wenxiong; Yang, Yijie; Kao, Ya-Chuan; Lee, Hiang Kwee; Chu, Rongrong; Pang, Yee Ling; Lay, Chee Leng; Li, Shuzhou; Ling, Xing Yi published an article.Related Products of 111-29-5 The title of the article was Modulating Orientational Order to Organize Polyhedral Nanoparticles into Plastic Crystals and Uniform Metacrystals. And the article contained the following:

In nanoparticle self-assembly, the current lack of strategy to modulate orientational order creates challenges in isolating large-area plastic crystals. Here, we achieve two orientationally distinct supercrystals using one nanoparticle shape, including plastic crystals and uniform metacrystals. Our approach integrates multi-faceted Archimedean polyhedra with mol.-level surface polymeric interactions to tune nanoparticle orientational order during self-assembly. Experiments and simulations show that coiled surface polymer chains limit interparticle interactions, creating various geometrical configurations among Archimedean polyhedra to form plastic crystals. In contrast, brush-like polymer chains enable mol. interdigitation between neighboring particles, favoring consistent particle configurations and result in uniform metacrystals. Our strategy enhances supercrystal diversity for polyhedra comprising multiple nondegenerate facets. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Related Products of 111-29-5

The Article related to silver orientational order polyhedral nanoparticle plastic crystal, nanoparticle self-assembly, nanoscale surface chemistry, orientational order, plastic crystals, uniform metacrystals and other aspects.Related Products of 111-29-5

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On July 31, 2021, Karsai, Syrus; Weiss, Christel; Luetgerath, Constantin; Ott, Isabel; Faulhaber, Jorg published an article.Electric Literature of 111-29-5 The title of the article was Comparison of novel aluminium lactate versus aluminium chloride-based antiperspirant in excessive axillary perspiration: First prospective cohort study. And the article contained the following:

Aluminum chloride-based antiperspirants are an effective topical therapeutic option for mild to moderate states of excessive perspiration. Its use is primarily limited by the occurrence of skin irritation, especially in sensitive skin types. The objective of this study was to compare the antiperspirant efficacy and tolerability of a novel antiperspirant with 12.5% aluminum lactate, and a 12.5% aluminum chloride-based antiperspirant. This cohort study was conducted as a two-sided self-assessment comparison between both preparations in healthy volunteers to generate selfcare-related data. Almost half of the participants stated that aluminum chloride was more efficacious than aluminum lactate; 22% stated aluminum lactate was more efficacious than aluminum chloride; 28% observed no difference in the efficacy of both preparations (p = 0.04). However, 88% described greater tolerability with aluminum lactate (p < 0.0001). In this study, aluminum lactate showed significantly greater tolerability than aluminum chloride, although the latter tended to show slightly greater efficacy. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Electric Literature of 111-29-5

The Article related to aluminum lactate chloride antiperspirant axillary perspiration human, aluminium chloride, aluminium lactate, antiperspirant, clinical efficacy, cohort study, excessive perspiration, tolerability and other aspects.Electric Literature of 111-29-5

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On August 9, 2021, Sun, Han; Xie, Xiaoxin; Huang, Qiu; Wang, Zhaoxu; Chen, Kejun; Li, Xiaolei; Gao, Jian; Li, Yutao; Li, Hong; Qiu, Jieshan; Zhou, Weidong published an article.Category: alcohols-buliding-blocks The title of the article was Fluorinated Poly-oxalate Electrolytes Stabilizing both Anode and Cathode Interfaces for All-Solid-State Li/NMC811 Batteries. And the article contained the following:

The relatively narrow electrochem. steady window and low ionic conductivity are two critical challenges for Li+-conducting solid polymer electrolytes (SPE). Here, a family of poly-oxalate(POE) structures were prepared as SPE; among them, POEs composed from diols with an odd number of carbons show higher ionic conductivity than those composed from diols with an even number of carbons, and the POE composed from propanediol (C5-POE) has the highest Li+ conductivity The HOMO (HOMO) electrons of POE were found located on the terminal units. When using trifluoroacetate as the terminating unit (POE-F), not only does the HOMO become more neg., but also the HOMO electrons shift to the middle oxalate units, improving the antioxidative capability. Furthermore, the interfacial compatibility across the Li-metal/POE-F is also improved by the generation of a LiF-based solid-electrolyte-interlayer(SEI). With the trifluoroacetate-terminated C5-POE (C5-POE-F) as the electrolyte and Li+-conducting binder in the cathode, the all-solid-state Li/LiNi0.8Mn0.1Co0.1O2(NMC811) cells showed significantly improved stability than the counterpart with poly-ether, providing a promising candidate for the forthcoming all-solid-state high-voltage Li-metal batteries. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Category: alcohols-buliding-blocks

The Article related to lithium nmc811 transesterification polycondensation process elec thermal morphol property, all-solid-state batteries, eutectic phenomenon, high-voltage cells, interfaces, polymer electrolytes and other aspects.Category: alcohols-buliding-blocks

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Alcohol – Wikipedia,
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