Category: 110-99-6

Wu, Yancong published the artcileZinc(II) and manganese(II) complexes with 1,3-bis(1-allylbenzimidazol-2-yl)-2-oxapropane: synthesis, crystal structures, antioxidant activities and DNA-binding properties, Computed Properties of 110-99-6, the main research area is zinc manganese allylbenzimidazolyloxapropane complex preparation crystal structure antioxidant; DNA interaction zinc manganese allylbenzimidazolyloxapropane complex.

Two new zinc(II) and manganese(II) complexes with the ligand 1,3-bis(1-allylbenzimidazol-2-yl)-2-oxopropane (aobb), with composition [Zn(aobb)2](pic)2·DMF·CH3OH and [Mn(aobb)(DMF)2(H2O)](pic)2 (pic = picrate; DMF = N,N-dimethylformamide), were synthesized and characterized by elemental anal., elec. conductivities, x-ray single-crystal diffraction, IR, and UV-visible spectra. Single-crystal x-ray revealed that Zn(II) and Mn(II) centers are both located in the six-coordinate distorted octahedral geometry. The DNA-binding modes of the ligand and the complexes were studied by electronic absorption titration, competitive binding with ethidium bromide and viscosity measurements. The exptl. evidence indicated the ligand and complexes interact with calf thymus DNA through intercalation. The binding strength follows the order >>aobb. Addnl., displays potential superoxide dismutase activity in vitro studies.

Journal of Coordination Chemistry published new progress about Antioxidants. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Computed Properties of 110-99-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hu, Han published the artcileDesign of 2,5-furandicarboxylic based polyesters degraded in different environmental conditions: Comprehensive experimental and theoretical study, Recommanded Product: 2,2′-Oxydiacetic acid, the main research area is furandicarboxylic acid polyester seawater biodegradability mol dynamic simulation; Catalytic mechanism; Degradable polyesters; Enzymatic degradation; Hydrolytic reaction; MD simulation.

Nowadays, the promotion and application of aliphatic-aromatic copolyesters, such as poly (butylene adipate-co-terephthalate) (PBAT), are growing into a general trend. Although the structures of diacids exerted substantial impacts on degradation behavior, the underlying mechanisms have rarely been studied. In this work, 2,5-Furandicarboxylic acid was combined with succinic acid (PBSF), adipic acid (PBAF) and diglycolic acid (PBDF) to prepare three kinds of copolyesters. They showed unique degradation behaviors in buffer, enzyme environment and artificial seawater. These characteristics are closely related to the structural compositions of diacids. PBAFs displayed impressive biodegradability when catalyzed by Candida antarctica lipase B (CALB), while the more hydrophilic PBDFs exhibited faster hydrolysis in both buffer and artificial seawater. PBSFs, with hydrophobic and short segments, obtained a relatively slower rate of hydrolysis and enzymic degradation The reactivity sites and hydrolytic pathway were revealed by the combination of DFT calculation and Fukui function anal. MD simulations, QM/MM optimizations and theozyme calculations showed that PBAF-CALB was prone to form a pre-reaction state, leading to the reduced energy barrier in the acylation process. This work revealed the effects of different structural features of diacids on polymer degradation and paved a way to design target biodegradable polymers in different degradation conditions.

Journal of Hazardous Materials published new progress about Biodegradability. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Recommanded Product: 2,2′-Oxydiacetic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Bing-Ben published the artcileLuminescent tetra-nuclear lanthanide-titanium-organic compound obtained by the mixed-ligand, Formula: C4H6O5, the main research area is nuclear lanthanide titanium organic compound mixed ligand luminescence.

A new heterometallic lanthanide-titanium-organic compound: [Eu2Ti2(dip)6(dig)2(H3O)2]·solvent (1, dip = diphenylglycolic acid, dig = diglycolic acid) has been synthesized under solvothermal conditions. Compound 1 contains a tetra-nuclear {Eu2Ti2} unit with the mixed ligands of dip and dig. Compound 1 displays intense red luminescence. Furthermore, the IR, PXRD, UV-vis and TGA spectra were also studied.

Chinese Journal of Structural Chemistry published new progress about Crystal structure. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Formula: C4H6O5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Huang, Xiaoping published the artcileSynthesis, characterization and SOD activity of bisbenzimidazole-based copper(II) complexes, Name: 2,2′-Oxydiacetic acid, the main research area is copper benzimidazole complex preparation crystal structure DFT; cyclic voltammetry SOD mimic activity copper benzimidazole complex.

Three bisbenzimidazole-copper(II) coordination complexes, [Cu(MIDB)(NO3)(CH3OH)](NO3) (1), [Cu(MIDB)(H2O)2](NO3)2 (2), and [Cu(ODB)2](ClO4)2 (3) (MIDB =N-Me bis(benzimidazol-2-ylmethyl) amine; ODB = bis(2-benzimidazolylmethyl) ether), were synthesized and characterized. The component ions in their crystals are linked by N-H…O, O-H… O, C-H…π and π…π interactions into three-dimensional networks which are quant. manifested by the Hirshfeld surface anal. Their frontier MO compositions and natural charge population were conducted theor. at the DFT/(UB3LYP)/6-31G+(d, p) level for the copper coordination units, indicating that the HOMO and LUMO orbitals are mainly contributed by the benzimidazole groups and the coordination bonds are stabilized by the delocalized stabilization energy between the lone-pair bonding orbitals from N and/or O atoms and the lone-pair anti bond orbitals of the copper center. The cyclic voltammetry showed irreversible one-electron redox reactions for the three complexes in DMF solutions SOD activity of 1 (IC50=1.34μM) was slightly better than that of 3 (IC50=1.36μM) by using the NBT method.

Journal of Molecular Structure published new progress about Crystal structure. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Name: 2,2′-Oxydiacetic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Yingjie published the artcileLanthanoid Heteroleptic Complexes with Cucurbit[5]uril and Dicarboxylate Ligands: From Discrete Structures to One-Dimensional and Two-Dimensional Polymers, Computed Properties of 110-99-6, the main research area is cucurbituril dicarboxylate lanthanoid discrete polymer preparation crystal mol structure; electronic structure cucurbituril diglycolate glutarate lanthanoid complex.

Lanthanoid heteroleptic complexes with cucurbit[5]uril {Q[5]} and two dicarboxylate ligands, e.g., diglycolic acid (H2DGC) and glutaric acid (H2GT), have been investigated with six new compounds featuring a tetrametallic and dimetallic discrete structures, a one-dimensional (1D) polymer, and three two-dimensional (2D) polymers with a unique honeycomb-type topol. being synthesized and structurally characterized. [La4(Q[5])3(DGC)2(NO3)2(H2O)12][La(DGC)(H2O)6]·7NO3·nH2O (1) has a tetrametallic structure constructed with three bis-bidentate Q[5] ligands linking two [La(DGC)(H2O)2]+ species in the middle and two [La(H2O)4(NO3)]2+ species at both ends. [Ce2(Q[5])(DGC)(NO3)(H2O)10]·3NO3·4H2O (2) has a dimetallic structure built up with a bis-bidentate Q[5] ligand linking [Ce(DGC)(H2O)3(NO3)] and [Ce(H2O)7]3+ on each side of the Q[5] portals. [Ce3(Q[5])3(DGC)2(H2O)9][Ce(DGC)(H2O)6]2·7NO3·nH2O (3) has a 1D polymeric structure built up with bis-bidentate Q[5] ligands in-turn linking one [Ce(H2O)6]3+ and two [Ce(DGC)(H2O)6]1+ cationic species. [Ln2(Q[5])2(GT)(H2O)6]·4NO3·nH2O [Ln = La (4), Ce (5) and Nd (6)] have similar 2D polymeric structures built up with two types of 9-fold coordinated Ln polyhedra linked by Q[5] via bis-bidentate carbonyl groups on both sides forming 1D chains which are further connected by bridging GT2- ligands to form 2D polymers with a unique honeycomb-type topol. Their vibrational modes and electronic structures have also been investigated.

Inorganic Chemistry published new progress about Crystal structure. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Computed Properties of 110-99-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Brager, Dominique M. published the artcilePb-Oxo Interactions in Uranyl Hybrid Materials: A Combined Experimental and Computational Analysis of Bonding and Spectroscopic Properties, Recommanded Product: 2,2′-Oxydiacetic acid, the main research area is solvothermal preparation lead uranyl terpyridine phenanthroline dicarboxylate tricarboxylate complex; crystal structure lead uranyl terpyridine phenanthroline dicarboxylate tricarboxylate complex; mol structure lead uranyl terpyridine phenanthroline dicarboxylate tricarboxylate complex; luminescence lead oxo uranyl terpyridine phenanthroline dicarboxylate tricarboxylate complex.

Reported are the syntheses and characterization of six new heterometallic UO22+/Pb2+ compounds The compounds are [UO2Pb(C4H4O5)2(H2O)].H2O (1), [UO2Pb(C15H11N3)(C9H6O6)(NO3)] (2), [UO2Pb(C15H11N3)(C9H6O6)(NO3)] (3), [UO2Pb2(C7H5NO4)2(NO3)2(H2O)2] (4), [UO2Pb(C8H6N4)(C10H2O8)].2H2O (5), and [UO2Pb(C15H11N3)(C10H10O4)4] (6). These materials feature rare instances of M-oxo interactions, which influence the bonding properties of the uranyl cation. The spectroscopic effects of these interactions were measured using luminescence and Raman spectroscopy. Computational d. functional theory-based natural bonding orbital and quantum theory of atoms in mols. methods indicate interactions arise predominantly through charge transfer between cationic units via the electron-donating uranyl O spx lone pair orbitals and electron-accepting Pb2+ p orbitals. The interaction strength varies as a function of Pb-oxo interaction distance and angle with energy values ranging from 0.47 kcal/mol in the longer contacts to 21.94 kcal/mol in the shorter contacts. Uranyl units with stronger interactions at the oxo display an asym. bond weakening and a loss of covalent character in the U=O bonds interacting closely with the Pb2+ ion. Luminescence quenching is observed in cases in which strong Pb-oxo interactions are present and is accompanied by red shifting of the uranyl sym. Raman stretch. Changes to inner sphere uranyl bonding manifest as a weakening of the U=O bond as a result of interaction with the Pb2+ ion. Comprehensive evaluation of the effects of metal ions on uranyl spectra supports modeling efforts probing uranyl bonding and may inform applications such as forensic signatures.

Inorganic Chemistry published new progress about Crystal structure. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Recommanded Product: 2,2′-Oxydiacetic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tuskaev, Vladislav A. published the artcileNovel titanium(IV) diolate complexes with additional O-donor as precatalyst for the synthesis of ultrahigh molecular weight polyethylene with reduced entanglement density: Influence of polymerization conditions and its implications on mechanical properties, Safety of 2,2′-Oxydiacetic acid, the main research area is titanium diolate complex precatalyst UHMWPE polymerization.

New alkoxo-titanium(IV) complexes with diolate ligand containing addnl. donor oxygen atom have been synthesized from readily available and scalable precursors. The structure of complex 4 was established by X-ray diffraction. Titanium atom adopts a distorted tetrahedral geometry formed by six oxygen atoms of ligands. The resulting complexes 3-4 are moderately or highly active in ethylene polymerization in the presence of {EtnAlCl3-n + Bu2Mg} binary cocatalysts. The influence of the nature of the solvent, the organoaluminum cocatalyst and the polymerization temperature on the activity of catalytic systems, and the properties of the resulting polymers were studied. The obtained polymers are linear polyethylene of ultrahigh mol. weight (up to 5.8·106 g mol-1) with a broad mol. weight distribution. The polymers are suitable for the modern methods of polymer processing-the solventless solid-state formation of super high-strength (breaking strength up to 2.8 GPa) and high-modulus (elastic modulus up to 140 GPa) oriented films and film tapes. The possibility of scaling up the synthesis of ultrahigh mol. weight polyethylene (UHMWPE) without a significant drop in the productivity of the catalytic system and polymer properties is shown. UHMWPE samples have been investigated by small-angle X-ray scattering (SAXS) methods to study the structural changes induced by solid-state drawing of nascent reactor powders.

Applied Organometallic Chemistry published new progress about Breaking strength. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Safety of 2,2′-Oxydiacetic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Oh-e, Masahito published the artcileInteractions Between Hydrated Cerium(III) Cations and Carboxylates in an Aqueous Solution: Anomalously Strong Complex Formation with Diglycolate, Suggesting a Chelate Effect, Safety of 2,2′-Oxydiacetic acid, the main research area is hydrated cerium cation carboxylate aqueous solution; anomalously strong complex diglycolate chelate.

Interactions between hydrated Ce3+ and various carboxylates are of fundamental interest. Anomalously strong interactions with Ce3+ occur when diglycolic acid (DGA) is added into a Ce3+ aqueous solution, unlike various other carboxylic acids. Herein, the complex-formation constants of Ce3+ with these acids are evaluated via absorption and emission spectra. Hydrated Ce3+ emits fluorescence with unity quantum yield; however, addition of various carboxylates statically quenches the fluorescence when Ce3+-carboxylate complexes form because the fluorescence lifetime is constant irresp. of the carboxylate concentration In the observed static quenching, the complex-formation constants obtained from the absorption and emission spectra (Kabs and Kem) agree well. The binding of Ce3+ by the conjugate Lewis bases, i.e., carboxylates, is approx. inversely proportional to the pH. Adding DGA into the system also statically quenches the fluorescence, but far more efficiently, even in a much weaker solution We rigorously deduce Kabs and Kem of Ce3+ with DGA without any approximation using comparable concentrations Careful fittings provide equivalent Kem and Kabs values, and by varying the pH and ionic strength, we confirm that this equivalence is an inherent property of the Ce3+-DGA system. The Lewis acid-base theory cannot explain why DGA binds to Ce3+ ~1000 times more strongly than the other carboxylates. This anomalously strong binding may be due to a chelate effect caused by the DGA’s central oxygen atom, which forms a five-membered ring with the conjugate Lewis bases of DGA; double chelate rings can also form, while bis-deprotonated DGA binds to Ce3+, facilitated by the central oxygen. Therefore, DGA enables efficient quenching through the chelate effect when it binds to Ce3+.

ACS Omega published new progress about Absorption spectra. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Safety of 2,2′-Oxydiacetic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Eckstrum, Kirsten published the artcileUtilization of a model hepatotoxic compound, diglycolic acid, to evaluate liver Organ-Chip performance and in vitro to in vivo concordance, COA of Formula: C4H6O5, the main research area is hepatotoxicity diglycolic acid liver organ chip performance; Diglycolic acid; Hepatocytes; In vivo concordance; Liver-chip; Microphysiological systems; Toxicity.

Microphysiol. systems (MPS) are emerging as potentially predictive models for drug safety and toxicity assessment. To assess the utility of these systems, the Food and Drug Administration partnered with Emulate to evaluate the Human Liver Organ-Chip in a regulatory setting. Diglycolic acid (DGA), a known hepatotoxin, was evaluated in the Liver-Chip and compared to a multi-well plate format to assess the Liver-Chip’s capabilities, limitations, overall performance, and concordance with other in vivo and in vitro studies. Cryopreserved primary human hepatocytes were exposed to DGA from 1 to 20 mM in Liver-Chips or traditional multi-well plates. We found that 10 mM or 20 mM of DGA was severely cytotoxic in both platforms, while 5 mM was mildly cytotoxic in Liver-Chips. Addnl., some hepatocyte functions were reduced with 5 mM DGA in Liver-Chips and 1 mM in well plates. Individual well effects were greater or occurred sooner than in the Liver-Chips. Examination of the performance of the Liver-Chip showed that variability was low for biochem. endpoints, but higher for imaging endpoints. Sensitivity and specificity were high. Only 3-4 Liver-Chips were necessary to detect an effect depending on the endpoint and effect size. The specifics of the experiment are found herein.

Food and Chemical Toxicology published new progress about Albumins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, COA of Formula: C4H6O5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Guerrero, Isabel published the artcileNoncovalently Linked Metallacarboranes on Functionalized Magnetic Nanoparticles as Highly Efficient, Robust, and Reusable Photocatalysts in Aqueous Medium, Related Products of alcohols-buliding-blocks, the main research area is noncovalently linked metallacarborane functionalized magnetic nanoparticle photooxidation heterogeneous catalysis; photocatalyst; heterogeneous catalysis; metallacarboranes; nanoparticles; photooxidation; surface functionalization.

A successful homogeneous photoredox catalyst has been fruitfully heterogenized on magnetic nanoparticles (MNPs) coated with a silica layer, keeping intact its homogeneous catalytic properties but gaining others due to the easy magnetic separation and recyclability. The amine-terminated magnetic silica nanoparticles linked noncovalently to H[3,3′-Co(1,2-C2B9H11)2]- (H[1]), termed MSNPs-NH2@H[1], are highly stable and do not produce any leakage of the photoredox catalyst H[1] in water. The magnetite MNPs were coated with SiO2 to provide colloidal stability and silanol groups to be tethered to amine-containing units. These were the MSNPs-NH2 on which was anchored, in water, the cobaltabis(dicarbollide) complex H[1] to obtain MSNPs-NH2@H[1]. Both MSNPs-NH2 and MSNPs-NH2@H[1] were evaluated to study the morphol., characterization, and colloidal stability of the MNPs produced. The heterogeneous MSNP-NH2@H[1] system was studied for the photooxidation of alcs., such as 1-phenylethanol, 1-hexanol, 1,6-hexanediol, or cyclohexanol among others, using catalyst loads of 0.1 and 0.01 mol %. Surfactants were introduced to prevent the aggregation of MNPs, and cetyl tri-Me ammonium chloride was chosen as a surfactant. This provided adequate stability, without hampering quick magnetic separation The results proved that the catalysis could be speeded up if aggregation was prevented. The recyclability of the catalytic system was demonstrated by performing 12 runs of the MSNPs-NH2@H[1] system, each one without loss of selectivity and yield. The cobaltabis(dicarbollide) catalyst supported on silica-coated magnetite nanoparticles has proven to be a robust, efficient, and easily reusable system for the photooxidation of alcs. in water, resulting in a green and sustainable heterogeneous catalytic system.

ACS Applied Materials & Interfaces published new progress about Carboranes Role: NUU (Other Use, Unclassified), PRP (Properties), USES (Uses). 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts