Leblanc, Virginie et al. published new experimental results with the assistance of cas: 110-03-2

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.Electric Literature of C8H18O2

Leblanc, Virginie;Yokota, Mariko;Grandidier, Marie-Helene;Yoshida, Daisuke;Adriaens, Els;Cotovio, Jose;Kyoutani, Daiki;Alepee, Nathalie published 《SkinEthic HCE Eye Irritation Test: Similar performance demonstrated after long distance shipment and extended storage conditions》. The research results were published in《Toxicology In Vitro》 in 2019.Electric Literature of C8H18O2 The article conveys some information:

Assessment of ocular irritation risk is an international regulatory requirement in the safety evaluation of products. In response to this need, L’Oreal developed the SkinEthic Human Corneal Epithelium (HCE) Eye Irritation Test (EIT) that has been included in OECD Test Guideline 492. SkinEthic HCE EIT is able to correctly and reliably identify chems. not requiring classification vs. labeling for eye irritation or serious eye damage according to UN GHS. In an effort to promote its global use, the performance of the method was evaluated after long-distance shipment and compared to European shipment conditions. Results obtained by Cosmos Tech. Center (Japan) after extended tissues transit were compared to results obtained in L’Oreál (France). Thirty-nine out of 40 blinded chems., representing different functional chem. classes, were consistently classified in both laboratories The SkinEthic HCE EIT test method was also evaluated for its performance after extended storage of the tissues. The performance was in agreement with the values reported in OECD TG 492, with an overall accuracy of 87.1% (based on 119 chems.), sensitivity of 95.5% and specificity of 73.5%. The reliability and relevance of SkinEthic HCE EIT test method after long-distance shipment and extended storage remain in agreement with regulatory validation criteria. The experimental procedure involved many compounds, such as 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) .

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.Electric Literature of C8H18O2

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Learn more about cas: 110-03-2 | Toxicology In Vitro 2021

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.COA of Formula: C8H18O2

Alepee, Nathalie;Leblanc, Virginie;Grandidier, Marie-Helene;Teluob, Severine;Viricel, Anaelle;Adriaens, Els;Michaut, Valerie published 《SkinEthic HCE Time-to-Toxicity on solids: A test method for distinguishing chemicals inducing serious eye damage, eye irritation and not requiring classification and labeling》. The research results were published in《Toxicology In Vitro》 in 2021.COA of Formula: C8H18O2 The article conveys some information:

This study describes the development of a Time-to-Toxicity approach for solids (TTS) based on the SkinEthic HCE tissue construct, capable to distinguish chems. that do not require classification for serious eye damage/eye irritation (No Cat.) from chems. that require classification for eye irritation (Cat. 2), and serious eye damage (Cat. 1). Briefly, the time-to-toxicity of 69 solids was evaluated by exposing SkinEthic HCE tissue constructs to the test chem. for two different time periods (30-min, and 120-min). Based on the viability observed for the different exposure periods, a classification was assigned. The within laboratory reproducibility in terms of concordance in classifications (3 UN GHS categories), based on a set of 48 solids, was 93.7%. Furthermore, 73.6% Cat. 1 (N = 24), 55.6% Cat. 2 (N = 15) and 72.2% No Cat. (N = 30) were correctly identified with the SkinEthic HCE TTS test method. This study provides evidence that the SkinEthic HCE Time-to-Toxicity method (multiple exposure times) can distinguish Cat. 2 solids from Cat. 1 solids. This is an added value compared to the SkinEthic HCE EITS method (single exposure time) that can distinguish No Cat. chems. from chems. that do require classification and labeling for eye irritation/serious eye damage (Cat. 2/Cat. 1). And 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) was used in the research process.

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.COA of Formula: C8H18O2

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Cas: 110-03-2 | Gurkan-Alp, A. Selenpublished an article in 2012

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.HPLC of Formula: 110-03-2

Gurkan-Alp, A. Selen;Mumcuoglu, Mine;Andac, Cenk A.;Dayanc, Emre;Cetin-Atalay, Rengul;Buyukbingol, Erdem published 《Synthesis, anticancer activities and molecular modeling studies of novel indole retinoid derivatives》. The research results were published in《European Journal of Medicinal Chemistry》 in 2012.HPLC of Formula: 110-03-2 The article conveys some information:

In this study, novel (E)-3-(5-substituted-1H-indol-3-yl)-1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-2-en-1-one derivatives were synthesized and their anticancer effects were determined in vitro. Novel indole retinoid compounds have anti-proliferative capacity in liver, breast, and colon cancer cell lines. This anti-proliferative effect was further analyzed in breast cancer cell line panel by using the most potent compound The latter can inhibit proliferation at very low IC50 concentrations in all of the breast cancer cell lines. Here, we present some evidence on apoptotic termination of cancer cell proliferation which may be primarily driven by the inhibition of RXRα and, to a lesser extent, RXRγ. And 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) was used in the research process.

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.HPLC of Formula: 110-03-2

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Cas: 110-03-2 | Zhu, Fen et al. made new progress in 2019

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.Related Products of 110-03-2

Zhu, Fen;Song, Yaqin;Liu, Shaohui;Nie, Jun;He, Yong published 《Preparation of polymerizable thermal initiator and its application in photo-induced thermal frontal polymerization》 in 2019. The article was appeared in 《European Polymer Journal》. They have made some progress in their research.Related Products of 110-03-2 The article mentions the following:

Photo-induced frontal polymerization has been growing interesting in the recent decades. However, the conflict among the frontal starting temperature, the storage stability and the high leachability remain problems to be solved. A new polymerizable methacrylate functionalized aliphatic peroxide thermal initiator (named as IEM-HDHP) through modifying methacrylate group into the 2,5-dihydroperoxy-2,5-dimethylhexane (HDHP) was successfully prepared In the photo-induced frontal polymerization investigated, IEM-HDHP showed medium photo-induced frontal polymerization starting temperature, frontal velocity and best storage stability compared with two com. thermal initiators (benzoyl peroxide (BPO) and 1-(2-hydroperoxypropan-2-yl) benzene) (CHP). What’s more, the lowest amount of small mol. leachability makes it outstanding from the two competitors. At the same time, IEM-HDHP is the only one to lead to the sample stick with complete and smooth appearance in this work. The experimental procedure involved many compounds, such as 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) .

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.Related Products of 110-03-2

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ACS Applied Energy Materials | Cas: 110-03-2 was involved in experiment

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) was used in the synthesis of six- and seven-membered heterocyclic boron compounds containing intramolecular N-B bond.Name: 2,5-Dimethyl-2,5-hexanediol

Zhou, Binghua;Zhou, Ying;Lai, Lujie;Chen, Ziling;Li, Jiajia;Jiang, Yunliang;Liu, Jian;Wang, Zhipeng;Xue, Zhigang published 《Fabrication of Borate-Based Porous Polymer Electrolytes Containing Cyclic Carbonate for High-Performance Lithium Metal Batteries》 in 2021. The article was appeared in 《ACS Applied Energy Materials》. They have made some progress in their research.Name: 2,5-Dimethyl-2,5-hexanediol The article mentions the following:

A series of borate-based porous polymer electrolytes (B-PPEs) is prepared by incorporating the copolymers containing cyclic boroxine and cyclic carbonate groups into poly(vinylidene fluoride) (PVDF) through the phase inversion method. The dense and well-interconnected pores are obtained in the polymer matrix when the content of the copolymer reached 40 wt %. The ethylene-oxygen chain segments in the copolymer can facilitate the mobility of polymer chains and form the uniform distribution of pores in the B-PPEs. The B-PPEs show an enhanced ionic conductivity of 1.32 x 10-3 S cm-1 at 30 °C, which is due to the uniform well-interconnected pores in the polymer host. The cyclic carbonate units interact with the liquid electrolyte, which could improve the electrolyte uptake capacity of the polymer matrix. Benefited from the Lewis acid-base interactions between boron moieties and the anions of the lithium salt, the lithium-ion transference number of B-PPEs is also significantly improved. Compared to the pure PVDF-based electrolyte, the Li/B-PPEs/Li cell displays a very stable polarization voltage and the long-time cycling for 1000 h at a c.d. of 0.2 mA cm-2. Moreover, the Li/B-PPEs/LiFePO4 cells deliver a higher capacity of 143.0 mAh g-1 at 0.2 C and 86% capacity retention after 150 cycles. The B-PPEs could be a promising candidate for enhancing the safety and electrochem. properties of lithium metal batteries.2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) were involved in the experimental procedure.

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) was used in the synthesis of six- and seven-membered heterocyclic boron compounds containing intramolecular N-B bond.Name: 2,5-Dimethyl-2,5-hexanediol

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Cas: 110-03-2 was involved in experiment | Asian Journal of Pharmaceutical and Clinical Research 2019

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.COA of Formula: C8H18O2

Abd-Alla, Howaida I.;Taie, Hanan A. A.;Abd-Elmotaleb, Marwa M. published 《Comparative phytochemical and biological investigation of five Glycine max (L.) Merrill genotypes》 in 2019. The article was appeared in 《Asian Journal of Pharmaceutical and Clinical Research》. They have made some progress in their research.COA of Formula: C8H18O2 The article mentions the following:

Soybean (Glycine max L. Merrill) is the world′s most important consumed seed legume. The objectives of the present study were to determine the variability in phytochem. composition and biol. activities between five genotypes of G. maximum Lipoidal matters were determined using glucose (GLC). Amino acids were detected by the amino acid analyzer. The phytoconstituents present within each ethanol extract was investigated by gas chromatog.-mass spectrometry. The amount of total phenolics, flavonoids, and tannins was analyzed using a spectrophotometric technique, based on Folin-Ciocalteu reagent, aluminum chloride colorimetric assay, and the modified vanillin hydrochloric acid method, resp. Quercetin, catechin, and gallic acid were used as standard compounds, resp. Isoflavones content were detected by high-performance liquid chromatog. (HPLC)/photodiode array (PDA). The radical scavenging and antioxidant capacity of the genotypes using different in vitro anal. assays such as 2,2-di-Ph,1-picryl hydrazyl, 2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), reducing power, metal chelating, and ferric reducing anti-oxidant power. Bu hydroxyl toluene and trolox were used as the reference antioxidant radical scavenger compounds Antitumor activity was evaluated by detecting the viability of Ehrlich ascites carcinoma cells on four different concentrations (1-5 mg/mL). GLC anal. showed the high value of total unsaturated fatty acids and 16 amino acids including glutamic acid with the highest concentration The variation between genotypes according to their chem. composition of the aldehydes, esters, ketones, alcoholics, and carboxylic content were reported. HPLC/PDA referred to the presence of daidzein, genistein, and in all genotypes. The results confirm the higher value of phytoconstituents of the genotype Giza 35 and Giza 21 as well as their better bioactivity. The experimental procedure involved many compounds, such as 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) .

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.COA of Formula: C8H18O2

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Kojima, Hajime et al. published new experimental results with the assistance of cas: 110-03-2

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.Computed Properties of C8H18O2

Computed Properties of C8H18O2In 2013, Kojima, Hajime;Hayashi, Kazuhiko;Sakaguchi, Hitoshi;Omori, Takashi;Otoizumi, Takuya;Sozu, Takashi;Kuwahara, Hirofumi;Hayashi, Takumi;Sakaguchi, Mayumi;Toyoda, Akemi;Goto, Haruka;Watanabe, Shinichi;Ahiko, Kyoko;Nakamura, Tsuneaki;Morimoto, Takashi published 《Second-phase validation study of short time exposure test for assessment of eye irritation potency of chemicals》. 《Toxicology In Vitro》published the findings. The article contains the following contents:

A Short Time Exposure (STE) test is a cytotoxicity test that uses SIRC cells (rabbit corneal cell line) to assess eye irritation potency following a 5-min chem. exposure. This second-phase validation study assessed the predictive capacity of the STE test using 40 coded test substances at three laboratories A Validation Management Team (VMT) then evaluated the predictivity of the STE test for United Nation (UN) Globally Harmonized System (GHS) categories using 63 test substances including the results of the first-phase validation study. The STE test can assess not only the severe or corrosive ocular irritants (corresponding to the UN GHS Category 1) but also non-irritant (corresponding to UN GHS Non Category) from other toxicity classes, especially for limited types of test substances. The predictivity by STE test, however, was insufficient for identification of UN GHS categories (Category 1, Category 2, or Non Category). These results suggest that the STE test can be recommended as an initial step in a top-down approach to identification of severe irritants and test substances that require classification for eye irritation (UN GHS Category 1) as well as an initial step in a bottom-up approach to identification of test substances that do not require classification for eye irritation (UN GHS Non Category) from other toxicity classes, especially for limited types of test substances. The STE test is not considered adequate for the identification of mild or moderate irritants (i.e., UN GHS Categories 2A and 2B) and severe irritants (UN GHS Category 1).2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) were involved in the experimental procedure.

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.Computed Properties of C8H18O2

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Journal of Medicinal Chemistry | Cas: 110-03-2 was involved in experiment

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.Recommanded Product: 2,5-Dimethyl-2,5-hexanediol

Yamada, Shoya;Kawasaki, Mayu;Fujihara, Michiko;Watanabe, Masaki;Takamura, Yuta;Takioku, Maho;Nishioka, Hiromi;Takeuchi, Yasuo;Makishima, Makoto;Motoyama, Tomoharu;Ito, Sohei;Tokiwa, Hiroaki;Nakano, Shogo;Kakuta, Hiroki published 《Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening》 in 2019. The article was appeared in 《Journal of Medicinal Chemistry》. They have made some progress in their research.Recommanded Product: 2,5-Dimethyl-2,5-hexanediol The article mentions the following:

Ligands for retinoid X receptors (RXRs), “rexinoids”, are attracting interest as candidates for therapy of type 2 diabetes and Alzheimer’s and Parkinson’s diseases. However, current screening methods for rexinoids are slow and require special apparatus or facilities. Here, we created 7-hydroxy-2-oxo-6-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-2H-chromene-3-carboxylic acid (10, CU-6PMN) as a new fluorescent RXR agonist and developed a screening system of rexinoids using 10. Compound 10 was designed based on the fact that umbelliferone emits strong fluorescence in a hydrophilic environment, but the fluorescence intensity decreases in hydrophobic environments such as the interior of proteins. The developed assay using 10 enabled screening of rexinoids to be performed easily within a few hours by monitoring changes of fluorescence intensity with widely available fluorescence microplate readers, without the need for processes such as filtration. The experimental procedure involved many compounds, such as 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) .

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.Recommanded Product: 2,5-Dimethyl-2,5-hexanediol

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Cas: 110-03-2 was involved in experiment | Nature Communications 2021

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.Recommanded Product: 110-03-2

Recommanded Product: 110-03-2《Selective deoxygenative alkylation of alcohols via photocatalytic domino radical fragmentations》 was published in 2021. The authors were Guo, Hong-Mei;Wu, Xuesong, and the article was included in《Nature Communications》. The author mentioned the following in the article:

A one-pot strategy for deoxygenative Giese reaction of alcs. with electron-deficient alkenes, by using xanthate salts as alc.-activating groups for radical generation under visible-light photoredox conditions in the presence of triphenylphosphine were reported. The convenient generation of xanthate salts and high reactivity of sequential C-S/C-O bond homolytic cleavage enable efficient deoxygenation of primary, secondary and tertiary alcs. with diverse functionality and structure to generate the corresponding alkyl radicals, including Me radical. Moreover, chemoselective radical monodeoxygenation of diols was achieved via selective formation of xanthate salts.2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) were involved in the experimental procedure.

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.Recommanded Product: 110-03-2

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Application of cas: 110-03-2 | Wang, Jintao et al. published an article in 2017

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.Recommanded Product: 2,5-Dimethyl-2,5-hexanediol

Recommanded Product: 2,5-Dimethyl-2,5-hexanediol《Hydrogenation of alkynes to cis-alkenes with hydrazine in air》 was published in 2017. The authors were Wang, Jintao;Xiong, Jiukai;Li, Juanjuan;Wang, Jiali;Wang, Kerang;Li, Xiaoliu, and the article was included in《Youji Huaxue》. The author mentioned the following in the article:

In this paper, a simple approach of selectively hydrogenation of alkynes to cis-alkenes with NH2NH2·H2O as a transfer hydrogenation agent in the presence of air without any catalysts or metals was developed. Furthermore, the configuration of cis-alkene was confirmed by the 2D NOESY spectrum.2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) were involved in the experimental procedure.

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.Recommanded Product: 2,5-Dimethyl-2,5-hexanediol

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