Category: 107-75-5

Adding a certain compound to certain chemical reactions, such as: 107-75-5, 7-Hydroxy-3,7-dimethyloctanal, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Quality Control of 7-Hydroxy-3,7-dimethyloctanal, blongs to alcohols-buliding-blocks compound. Quality Control of 7-Hydroxy-3,7-dimethyloctanal

General procedure: Amine (0.1 mmol) in MeOH (2 mL) was treated with an equimolaramount of aldehyde in MeOH (1 mL), held at 20C for 12 h, and evaporated. PMR and 13C NMR spectra of imines (+)-12 and(+)-(13) agreed with the literature [21] for (-)-(12) and (-)-(13). The yields of imines (+)- and (-)-(12) were 98 and 97%,respectively; of (+)- and (-)-(13), 96%.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,107-75-5, 7-Hydroxy-3,7-dimethyloctanal, and friends who are interested can also refer to it.

Reference:
Article; Zakharenko; Mozhaitsev; Suslov; Korchagina; Volcho; Salakhutdinov; Lavrik; Chemistry of Natural Compounds; vol. 54; 4; (2018); p. 672 – 676; Khim. Prir. Soedin.; 4; (2018); p. 569 – 572,4;,
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Reference of 107-75-5, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 107-75-5 as follows.

General procedure: A solution of amine 14 in methanol (4 mL) was addedunder stirring to the corresponding aldehyde. After 3 hours NaBH4 was added to reaction mixture and stirred for an additional 1.5 hours, then the reaction mixture was treated with8 ml of saturated NaCl solution and allowed to stand for 30 minutes. The product was extracted with ether (6×10 ml).Isolation of amines 15a-d from the reaction mixture wasaccomplished by precipitation from solution in ether in theform of hydrochloric salts by adding to a solution of ethylacetatesaturated with hydrogen chloride. The precipitatewas filtered off, washed with ether and treated with saturatedsodium bicarbonate solution. The product was extractedfrom the aqueous solution with ether.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,107-75-5, its application will become more common.

Reference:
Article; Ponomarev, Konstantin; Morozova, Ekaterina; Pavlova, Alla; Suslov, Evgeniy; Korchagina, Dina; Nefedov, Andrej; Tolstikova, Tat’yana; Volcho, Konstantin; Salakhutdinov, Nariman; Medicinal Chemistry; vol. 13; 8; (2017); p. 773 – 779;,
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Adding a certain compound to certain chemical reactions, such as: 107-75-5, 7-Hydroxy-3,7-dimethyloctanal, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 107-75-5, blongs to alcohols-buliding-blocks compound. Recommanded Product: 107-75-5

Compounds 46: 7-hyroxycitronellal (140 mu, 0.75 mmol), Cu(OTf)2 (2.2 mg, 2.5 mol %), ethanethiol (108 mu, 1.5 mmol) and 1,3,5- trimethoxybenzene (42 mg, 0.25 mmol) were reacted according to method B. The mixture was stirred for 2 h at rt. After the addition of Et3SiH (116 mu, 0.75 mmol) the reaction was stirred for 1 h at room temperature. The residual material was purified by column chromatography (silica gel 40-60, hexane / ethyl acetate 80:20) affording compound 46 (64 mg, 79% yield) as a thick oil. Characterization data of compound 46: lH NMR (CDCl3/400 MHz): delta 6.13 (s, 2H), 3.80 (s, 3H), 6.79 (s, 6H), 2.60 – 2.48 (m, 2H), 1.49 – 1.24 (m, 9H), 1.21 (s, 6H), 0.93 (d, J = 6.2, Hz, 3H); 13C NMR (CDCl3/100 MHz): 6 159.0, 158.7, 112.3, 90.6, 71.1, 55.7, 55.3, 44.4, 37.3, 36.6, 32.9, 29.3, 29.2, 21.6, 20.1, 19.7; HRMS (ESI): m/z calcd for Ci9H3204 [M+H]+ 325.2373 found 325.2363.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,107-75-5, its application will become more common.

Reference:
Patent; B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY; PAPPO, Doron; PARNES, Regev; (87 pag.)WO2016/132355; (2016); A1;,
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The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 107-75-5, name is 7-Hydroxy-3,7-dimethyloctanal. This compound has unique chemical properties. The synthetic route is as follows. 107-75-5

General procedure: Aldehyde (2 equiv) was added to a mixture of N-acyl phthalimide (1 equiv), potassium phthalimide (20 mg, 0.11 mmol, 0.2 equiv), NaI (16 mg, 0.11 mmol, 0.2 equiv), 4 A MS (100 mg), MeCN (0.53 mL), and EtOAc (0.53 mL) at room temperature with stirring. After 24 h, the mixture was diluted in Et2O, and sequentially washed with satd aq NH4Cl (1¡Á), 1 M aq NaOH (3¡Á), and brine (1¡Á). The organic phase was dried (MgSO4) and concentrated. The crude material was purified by normal phase flash chromatography using a mixture of hexanes/EtOAc eluent.

Statistics shows that 107-75-5 is playing an increasingly important role. we look forward to future research findings about 7-Hydroxy-3,7-dimethyloctanal.

Reference:
Article; Enright, Robert N.; Grinde, Jeffrey L.; Wurtz, Lincoln I.; Paeth, Matthew S.; Wittman, Tekoa R.; Cliff, Emily R.; Sankari, Yessra T.; Henningsen, Lucas T.; Tan, Chuchen; Scanlon, Joseph D.; Willoughby, Patrick H.; Tetrahedron; vol. 72; 41; (2016); p. 6397 – 6408;,
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107-75-5, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 107-75-5, name is 7-Hydroxy-3,7-dimethyloctanal. A new synthetic method of this compound is introduced below.

Compound 33: 7-hyroxycitronellal (140 mu, 0.75 mmol), Cu(OTf)2 (2.2 mg, 2.5 mol ethanethiol (108 mu, 1.5 mmol) and 1,3,5- trimethoxybenzene (42 mg, 0.25 mmol) were reacted according to method A. The mixture was stirred for 2 h at room temperature. The residual material was purified by column chromatography (silica gel 40-60, hexane / ethyl acetate 80:20) affording compound 33 (68 mg, 71% yield) as a thick oil. Characterization data of compound 33: lH NMR (CDCl3/400 MHz): delta 6.12 (s, 1H), 6.09 (s, 1H), 4.54 – 4.46 (m, 1H), 3.80 (s, 3H), 3.78 (s, 6H), 2.51 – 2.32 (m, 3H), 1.96 – 1.84 (m, 1H), 1.56 – 1.47 (m, 1H), 1.40 – 1.32 (m, 4H), 1.24 – 1.19 (m, 5H), 1.17 (s, 3H), 1.15 (s, 3H), 0.82 (t, J = 4.5 Hz, 3H); 13C NMR (CDCl3/100 MHz): delta 160.2, 159.8, 158.2, 112.4, 111.4, 91.7, 90.3, 71.0, 55.9, 55.7, 55.2, 44.2, 41.3, 38.1, 37.1, 31.4, 29.1, 26.3, 21.6, 20.0, 19.4, 15.0; HRMS (ESI): m/z calcd for C2iH3604S [M+Na]+ 407.2227 found 407.2218.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,107-75-5, 7-Hydroxy-3,7-dimethyloctanal, and friends who are interested can also refer to it.

Reference:
Patent; B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY; PAPPO, Doron; PARNES, Regev; (87 pag.)WO2016/132355; (2016); A1;,
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107-75-5, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 107-75-5, name is 7-Hydroxy-3,7-dimethyloctanal. A new synthetic method of this compound is introduced below.

General procedure: Under an atmosphere of argon, the carboxyalkyl triphenyl phosphonium bromide (2.0 equiv) is dissolved in anhydrous THF (0.6 M) The suspension is cooled to 0 C and KOt-Bu (powder or 1 M in THF; 4.0 equiv) is added dropwise. After 30 min of stirring at room temperature, a solution of the aldehyde (1.0 equiv) in anhydrous THF (2 M) is added dropwise at 0 C. The reaction is stirred at room temperature and after the aldehyde is consumed, the mixture is quenched with 1 M aq. HCl solution (20 mL), extracted with Et2O (3 30 mL) and washed with H2O (2 60 mL). The combined organic layers are washed with brine, dried over anhydrous Na2SO4, filtered and the solvent is removed under reduced pressure. The residue is purified on silica gel to yield the title compound.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,107-75-5, 7-Hydroxy-3,7-dimethyloctanal, and friends who are interested can also refer to it.

Reference:
Article; Rode, Katharina; Palomba, Martina; Ortgies, Stefan; Rieger, Rene; Breder, Alexander; Synthesis; vol. 50; 19; (2018); p. 3875 – 3885;,
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107-75-5, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 107-75-5, name is 7-Hydroxy-3,7-dimethyloctanal, molecular formula is C10H20O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

The experimental methods consisted of two steps: the synthesis step, and the characterization. The synthesis step was begun by weighing of raw materials that were hydroxycitronellal and methyl anthranilate. The aurantiol synthesis was carriedout at a temperature of about 90¡À5C with modification of time for 15 min, 30 min, 1 h, 2 h, 3 h,and 4 hours.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 107-75-5, 7-Hydroxy-3,7-dimethyloctanal, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Irawan, Candra; Indryati, Suci; Lestari, Endang Sri; Hidaningrum, Arinzani; Supriyono; Oriental Journal of Chemistry; vol. 34; 1; (2018); p. 394 – 400;,
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