Category: 10602-04-7

Traeger, Hanna; Ghielmetti, Alyssa; Sagara, Yoshimitsu; Schrettl, Stephen; Weder, Christoph published the artcile< Supramolecular Rings as Building Blocks for Stimuli-Responsive Materials>, Computed Properties of 10602-04-7, the main research area is stimuli responsive material supramol ring; benzothiadiazole; chromogenic; fluorescence; luminescence; naphthalene diimide; quenching; stimuli-responsive polymers.

Stimuli-responsive polymers are of great interest due to their ability to translate changing environmental conditions into responses in defined materials. One possibility to impart such behavior is the incorporation of optically active mols. into a polymer host. Here, we describe how sensor mols. that consist of a π-extended benzothiadiazole emitter and a naphthalene diimide quencher can be exploited in this context. The two optically active entities were connected via different spacers and, thanks to attractive intramol. interactions between them, the new sensor mols. assembled into cyclic structures in which the fluorescence was quenched by up to 43% when compared to solutions of the individual dyes. Detailed spectroscopic investigations of the sensor mols. in solution show that the extent of donor/acceptor interactions is influenced by various factors, including solvent polarity and ion concentration The new sensor mol. was covalently incorporated into a polyurethane; the investigation of the optical characteristics in both the solid and solvent-swollen states indicates that a stimulus-induced formation of associated dye pairs is possible in polymeric materials. Indeed, a solvatochromic quenching effect similar to the behavior in solution was observed for solvent-swollen polymer samples, leading to an effective change of the green emission color of the dye to a yellow color.

Gels published new progress about Differential scanning calorimetry. 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Computed Properties of 10602-04-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mukhopadhyay, Arindam; Bernard, Brianna; Liu, Kaixuan; Paulino, Victor; Liu, Chuan; Donley, Carrie; Olivier, Jean-Hubert published the artcile< Molecular Strategies to Modulate the Electrochemical Properties of P-Type Si(111) Surfaces Covalently Functionalized with Ferrocene and Naphthalene Diimide>, Name: (4-Ethynylphenyl)methanol, the main research area is electrochem silicon covalently functionalized ferrocene naphthalene diimide.

The surface coverage and mol. composition of redox-active mols. anchored on conductive surfaces regulate the kinetic and thermodn. parameters of charge transfer reactions, providing a means to tune the electrochem. properties of hybrid materials. Herein, anchoring strategies and structural properties of redox-active probes, derived from ferrocene (Fc) and naphthalene diimide (NDI), regulate the electrochem. properties of functionalized p-doped Si(111) surfaces. Covalent functionalization of H-terminated Si(111) surfaces with Fc and NDI affords redox-active hybrid interfaces characterized through microscopy, spectroscopy, and voltammetry methods. Mol. design and synthetic grafting strategies modulate the electrochem. properties of the Fc-functionalized Si surfaces with a much higher (∼25 times) surface coverage (1.25 × mol. cm-2) for 1-step photografting compared to divergent synthetic routes. The thermal grafting of an alkadiyne followed by click reaction with ferrocenyl-azide leads to one of the highest surface coverages ( 9.97 × 10-10 mol cm-2) of organo-Fe reported and a significant anodic shift of the half-potential (>350 mV) compared to photografting methods. Similar experiments with NDI units exhibited electrochem. properties that diverge from those recorded for NDI in solution The results presented herein offer access to novel redox-active Si interfaces that evidence tunable electrochem. properties of potential interest for microelectronics applications.

Journal of Physical Chemistry B published new progress about Chemically modified electrodes. 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Name: (4-Ethynylphenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hou, Zhong-Wei; Li, Laiqiang; Wang, Lei published the artcile< Regio- and stereoselective electrochemical selenoalkylation of alkynes with 1,3-dicarbonyl compounds and diselenides>, Synthetic Route of 10602-04-7, the main research area is selenated alkene preparation regioselective diastereoselective; aryl alkyne dicarbonyl compound diselenide selenoalkylation electrochem.

A regio- and stereoselective electrochem. approach for the seleno(monofluoro)alkylation of alkynes with 1,3-dicarbonyl compounds and diselenides has been developed. The electrosynthesis method utilizes C-H substrates as radical precursors and the source of carbon atoms, avoiding dependence on pre-functionalized substrates. A series of selenated alkenes, e.g., I, were prepared with satisfactory outcomes under noble metal-free and oxidizing reagent-free conditions.

Organic Chemistry Frontiers published new progress about 1,3-Dicarbonyl compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Synthetic Route of 10602-04-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Garlatti, Laura; Huet, Raphael; Alvarez, Karine published the artcile< Efficient access to 3'-deoxy-3'-(4-substituted-1,2,3-triazol-1-yl)-thymidine derivatives via ligand-promoted CuAAC>, Computed Properties of 10602-04-7, the main research area is click alkyne azide triazole cycloaddition catalyst preparation nucleoside.

Herein we describe an efficient and rapid access to 3′-deoxy-3′-(4-substituted-1,2,3-triazol-1-yl)-thymidine derivatives, e.g. I, using 1,3-dipolar cycloaddition reaction catalyzed by copper(I). Innovative conditions allow us to generate target compounds in a one-pot reaction mixing 3′-azido-3′-deoxythymidine, alkyne, copper sulfate pentahydrate, sodium ascorbate and tris(benzyltriazolylmethyl)amine in a water:tert-butanol solvent mixture Rapid treatment of the reaction and subsequent flash purification chromatog. afforded pure compounds in an overall yield of 71-100%. All eleven synthesized compounds were identified on the basis of their spectral data anal. (1H, 13C, 2D NMR and high-resolution mass spectra).

Tetrahedron published new progress about 1,3-Dipolar cycloaddition reaction. 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Computed Properties of 10602-04-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Su, Lebin; Xie, Shimin; Dong, Jianyu; Liu, Feng; Yin, Shuang-Feng; Zhou, Yongbo published the artcile< Copper-Catalyzed Nitrogen Atom Transfer to Isoquinolines via C-N Triple Bond Cleavage and Three-Component Cyclization>, Name: (4-Ethynylphenyl)methanol, the main research area is bromoaryl ketone alkyne acetonitrile copper catalyst three component cyclization; isoquinoline preparation.

A copper(I)-catalyzed tandem reaction of 2-bromoaryl ketones, terminal alkynes, and CH3CN was developed, which combines N atom transfer and three-component [3 + 2 + 1] cyclization, and efficiently produces densely functionalized isoquinolines in a facile, highly selective, and general manner. In the reaction, the formation of aromatic C-N bonds along with the complete C-N triple bond cleavage was first realized; Cu(III)-acetylide species might serve as the intermediates, which allow highly selective 6-endo-dig cyclization.

Organic Letters published new progress about Alkynes, aryl Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Name: (4-Ethynylphenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chalupnik, Paulina; Vialko, Alina; Pickering, Darryl S.; Hinkkanen, Markus; Donbosco, Stephanie; Moeller, Thor C.; Jensen, Anders A.; Nielsen, Birgitte; Bay, Yasmin; Kristensen, Anders S.; Johansen, Tommy N.; Latka, Kamil; Bajda, Marek; Szymanska, Ewa published the artcile< Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype>, COA of Formula: C9H8O, the main research area is quinoxalinedione preparation glutamate receptor antagonist; glutamate receptors; kainate receptors; subunit selectivity.

In search of selective ligands for the GluK3 kainate receptor subtype, a series of I [R = 3-Me Ph, 4-Me Ph, 4-Et Ph, etc] analogs was synthesized and pharmacol. characterized at selected recombinant ionotropic glutamate receptors. Among them, compound I [R = imidazo[1,2-b]pyridazin-3-ylmethyl] was found to be a competitive GluK3 antagonist with submicromolar affinity and unprecedented high binding selectivity, showing a 400-fold preference for GluK3 over other homomeric receptors GluK1, GluK2, GluK5 and GluA2. Furthermore, in functional assays performed for selected metabotropic glutamate receptor subtypes, I [R = imidazo[1,2-b]pyridazin-3-ylmethyl] did not show agonist or antagonist activity. The mol. determinants underlying the observed affinity profile of I [R = imidazo[1,2-b]pyridazin-3-ylmethyl] were analyzed using mol. docking and mol. dynamics simulations performed for individual GluK1 and GluK3 ligand-binding domains.

International Journal of Molecular Sciences published new progress about Kainate receptors Role: BSU (Biological Study, Unclassified), BIOL (Biological Study) (GluK3). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, COA of Formula: C9H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Saito, Tatsuya; Takojima, Kaoru; Oyama, Takafumi; Hatanaka, Shintaro; Konno, Takashi; Yamamoto, Takuya; Tajima, Kenji; Isono, Takuya; Satoh, Toshifumi published the artcile< Trimethyl Glycine as an Environmentally Benign and Biocompatible Organocatalyst for Ring-Opening Polymerization of Cyclic Carbonate>, Application of C9H8O, the main research area is trimethyl glycine environmentally benign biocompatible organocatalyst.

Tri-Me glycine (TMG), a natural product found in plants as well as in humans, was demonstrated to be an efficient catalyst for the ring-opening polymerization (ROP) of cyclic carbonate, enabling the environmentally benign synthesis of aliphatic polycarbonate (APC). The ROP of trimethylene carbonate (TMC) using TMG proceeded under the bulk condition at 70 °C to give poly(trimethylene carbonate), possessing controlled mol. weight (∼4000) and low dispersity (∼1.22). The results of a matrix-assisted laser desorption/ionization time-of-flight mass spectral anal. and a chain extension experiment confirmed the controlled/living nature of the present ROP system, where side reactions, such as inter- and intramol. transesterifications, were minimized during the polymerization The screening of TMG analogs as a catalyst for ROP revealed that the combination of the carboxylate and quaternary ammonium moieties in TMG is an essential structural requirement. The Fourier transform IR analyses of TMC and alc. initiator in the presence/absence of TMG confirmed the biactivation property of the TMG. End-functionalized APCs were obtained using alc. initiators bearing clickable functionalities, such as azido and ethynyl groups. Furthermore, we demonstrated the synthesis of APC-diol and -triol, which can be used as prepolymers for APC-based polyurethane.

ACS Sustainable Chemistry & Engineering published new progress about Polycarbonates, aliphatic Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Application of C9H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Murugesan, Kathiravan; Alshammari, Ahmad S.; Sohail, Manzar; Beller, Matthias; Jagadeesh, Rajenahally V. published the artcile< Monodisperse nickel-nanoparticles for stereo- and chemoselective hydrogenation of alkynes to alkenes>, SDS of cas: 10602-04-7, the main research area is alkene preparation diastereoselective chemoselective green chem; alkyne hydrogenation monodisperse nickel nanocatalyst.

The use of monosaccharides for the preparation of novel nickel nanoparticles (NP), which constitute selective hydrogenation catalysts has been reported. For example, immobilization of fructose and Ni(OAc)2 on silica and subsequent pyrolysis under inert atm. produced graphitic shells encapsulated Ni-NP with uniform size and distribution. Interestingly, fructose acts as structure controlling compound to generate specific graphitic layers and the formation of monodisperse NP. These nanoparticles enable the hydrogenation of a series of functionalized and structurally diverse aromatic, heterocyclic and aliphatic alkynes R1CCR2 (R1 = 1-hydroxyoct-8-yl, Ph, cyclohexyl, benzothiophen-3-yl, etc.; R2 = H, Et, Ph, 1,3-dioxo-1,3-dihydro-2-benzofuran-5-yl, etc.) to the corresponding alkenes R1CH=CHR2 with excellent stereo- (98-100% Z-alkene formation) and chemoselectivity.

Journal of Catalysis published new progress about Alkenes Role: SPN (Synthetic Preparation), PREP (Preparation). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, SDS of cas: 10602-04-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liao, Yangzhen; Ran, Yu; Liu, Guijun; Liu, Peijun; Liu, Xiaozu published the artcile< Transition-metal-free radical relay cyclization of vinyl azides with 1,4-dihydropyridines involving a 1,5-hydrogen-atom transfer: access to α-tetralone scaffolds>, COA of Formula: C9H8O, the main research area is tetralone scaffold preparation green chem diastereoselective; vinyl azide dihydropyridine radical hydrogen transfer cyclization.

The remote C(sp3)-H functionalization enabled by a radical-mediated 1,5-hydrogen-atom transfer (HAT) process using 1,4-dihydropyridines I (R = cyclohexyl, 3-phenyl-2-methylpropyl, 1-cyclohexylethyl, etc.; R1 = C(O)OEt, CN) and vinyl azides R2C(=CH2)N3 (R2 = 2-chlorophenyl, 1-naphthyl, benzofuran-2-yl, etc.) as precursors has been described. In this study, 1,4-dihydropyridines I can function as 1,2-diradical synthons through sequential homolytic cleavage of an ipso-C-C bond and a β-C(sp3)-H bond. This reaction offers facile access to a diverse range of α-tetralones e.g., II with excellent stereoselectivity. The utility of the present method is further highlighted by its application to rapid assembly of the tetracyclic scaffold present in furanosteroids as well as the synthesis of aromatic amines.

Organic Chemistry Frontiers published new progress about Alkyl azides Role: RCT (Reactant), RGT (Reagent), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, COA of Formula: C9H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Xuan; Jiang, Min; Zhu, Xiaolong; Song, Xiuyan; Deng, Qirong; Lv, Jian; Yang, Daoshan published the artcile< A desulphurization strategy for Sonogashira couplings by visible light/copper catalysis>, Name: (4-Ethynylphenyl)methanol, the main research area is alkyne sulfonium salt desulfurization Sonogashira coupling copper catalyst.

Herein, a new copper-based catalyst, [(binap)(tpy)Cu]Cl I applied in the visible-light promoted Sonogashira coupling reactions has been developed. This mild protocol results in various substituted alkynes RCCH (R = Ph, 2-naphthyl, 2-thienyl, etc.) from simple sulfonium salts II (R1 = Ph, 1-naphthyl, 2H-1,3-benzodioxol-5-yl, etc.) which can be easily prepared from com. available and inexpensive substrates. This study will broaden the still limited strategies of copper photocatalysts in organic transformations.

Organic Chemistry Frontiers published new progress about Alkynes, aryl Role: RCT (Reactant), RACT (Reactant or Reagent). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Name: (4-Ethynylphenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts