Category: 103694-68-4

Electric Literature of 103694-68-4, Adding some certain compound to certain chemical reactions, such as: 103694-68-4, name is 2,2-Dimethyl-3-(m-tolyl)propan-1-ol,molecular formula is C12H18O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 103694-68-4.

5% Rh/C (450mg, 15% w/w) was charged into a 5OmL autoclave vessel containing a mixture of 2,2-dimethyl-3-(3-methylplienyl)propan-l-ol (6g, 34mmol) in water (17mL). The mixture was vigorously stirred under an hydrogen atmosphere (lOBar) at 600C for 6h. The reaction mixture was filtered and the filtrate was extracted with MTBE (25mL), dried over magnesium sulphate and concentrated. The resulting crude product was distilled with a bulb-to-bulb distillation (2.5mBar, 900C) to give 2,2-dimethyl-3-(3- methylcyclohexyl)propan-l-ol (5.1g, gc purity > 99%; yield 82%).Odour: aldehydic, fatty /greasy, floral.Analytical data:1H NMR (400 MHz, CHLOROFORM-d) ppm: 0.51-0.88 (m, 2H), 0.79-0.87 (m, 9H), 0.95-1.76 (m, 10H), 1.87 (br. s., IH), 3.25 (s, 2H).13C NMR (101 MHz, CHLOROFORM-^ ppm: 22.90 (q, 1C), 24.30 (q, 1C), 24.31 (t, 1C), 26.53 (d, 1C), 32.90 (d, 1C), 33.58 (t, 1C), 34.83 (t, 1C), 35.48 (t, 1C), 35.68 (s, 1C), 44.95 (t, 1C), 46.26 (t, 1C), 72.32 (t, 1C). EPO MS: Major isomer: m/z (relative intensity) (no M+), 153 (34), 137 (3), 111 (11), 97 (100), 83 (29), 69 (20), 55 (74), 41 (23).Minor isomer m/z (relative intensity): (no M+), 153 (33), 137 (6), 111 (11), 97 (100), 83 (30), 69 (23), 55 (79), 41 (25).

According to the analysis of related databases, 103694-68-4, the application of this compound in the production field has become more and more popular.

Reference:
Patent; QUEST INTERNATIONAL SERVICES B.V.; WO2008/53148; (2008); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Adding a certain compound to certain chemical reactions, such as: 103694-68-4, 2,2-Dimethyl-3-(m-tolyl)propan-1-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: 2,2-Dimethyl-3-(m-tolyl)propan-1-ol, blongs to alcohols-buliding-blocks compound. name: 2,2-Dimethyl-3-(m-tolyl)propan-1-ol

EXAMPLE 6 Manufacture of 1-methoxy-2,2-dimethyl-3-(3-methylphenyl)-propane In a 250 ml three-necked flask flushed with argon, 4.5 g of 2,2-dimethyl-3-(3-methylphenyl)-propan-1-ol (according to Example 5) in 50 ml of dry tetrahydrofuran were boiled for 11/2 hours under reflux with 0.7 g of sodium hydride. 3.2 g of dimethyl sulfate in 30 ml of tetrahydrofuran were then added dropwise thereto and the mixture was boiled under reflux for a further hour. After leaving the reaction mixture to stand for 24 hours, it was extracted by shaking with 20 ml of 10% by weight sodium hydroxide solution. Finally, the organic phase was dried with potassium carbonate and subjected to fractional distillation. 3.6 g of end product were obtained at 52 C./0.12 mbar.

The synthetic route of 103694-68-4 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Consortium fur Elektrochemische Industrie GmbH; US4710316; (1987); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts