100-83-4 Archives - Page 6 of 10 - Alcohols-buliding-blocks

Ramesh, Rathinam’s team published research in Polycyclic Aromatic Compounds in 2020 | CAS: 100-83-4

3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.HPLC of Formula: 100-83-4

《Innovative Green Synthesis of 4-Aryl-Pyrazolo[5,6]Pyrano[2,3-d]Pyrimidines under Catalyst-Free Conditions》 was published in Polycyclic Aromatic Compounds in 2020. These research results belong to Ramesh, Rathinam; Tamilselvi, Velmurugan; Vadivel, Pullar; Lalitha, Appaswami. HPLC of Formula: 100-83-4 The article mentions the following:

A clean, cost-effective and practical approach was described for the synthesis of 4-aryl-pyrazolo[5,6]pyrano[2,3-d]pyrimidines I [R = Ph, 4-MeOC6H4, 2,4-Cl2C6H3, etc.; X = O, S] by four-component condensation of Et acetoacetate, hydrazine hydrate, aromatic aldehydes and barbituric/thiobarbituric acid in catalyst-free aqueous ethanol system. The reactions were assisted by water, there by leading to the development of ‘water chem.’ provided the products in good yields in shorter reaction times. Environmental benignity, neutral reaction conditions, wide range of functional group tolerance, facile exptl. and work-up procedures were the prominent features of this greener protocol. The experimental process involved the reaction of 3-Hydroxybenzaldehyde(cas: 100-83-4HPLC of Formula: 100-83-4)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ramesh, Rathinam’s team published research in Polycyclic Aromatic Compounds in 2020 | CAS: 100-83-4

3-Hydroxybenzaldehyde(cas: 100-83-4) is used as an ionophore, during the development of an highly selective and sensitive PVC membrane sensor, which can be used as a Tb3+ ion selective electrode.Formula: C7H6O2

Formula: C7H6O2In 2020 ,《An Organocatalytic Newer Synthetic Strategy Toward the Access of Polyfunctionalized 4H-Pyrans via Multicomponent Reactions》 appeared in Polycyclic Aromatic Compounds. The author of the article were Ramesh, Rathinam; Jayamathi, Jayaraj; Karthika, Chinnagoundar; Malecki, Jan Grzegorz; Lalitha, Appaswami. The article conveys some information:

An energy efficient, facile, and environmentally benign synthetic method to obtain pharmaceutically fortunate, diverse 4H-pyrans from frequently accessible aryl aldehydes, malononitrile, and dissimilar 1,3-diketoesters is described. The reactions took place smoothly at ambient temperature using 2-aminopyridine as a low-cost organocatalyst. The present domino strategy furnishes, the desired products in high yields with shorter reaction times. The structures of the o-nitro substituted skeletons were unambiguously confirmed by mono-crystal XRD. The results came from multiple reactions, including the reaction of 3-Hydroxybenzaldehyde(cas: 100-83-4Formula: C7H6O2)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Esmaeili, Rozhin’s team published research in Journal of Molecular Structure in 2020 | CAS: 100-83-4

Recommanded Product: 3-HydroxybenzaldehydeIn 2020 ,《A highly efficient one-pot multicomponent synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones catalyzed by strontium pyroarsenate nano-plates》 was published in Journal of Molecular Structure. The article was written by Esmaeili, Rozhin; Kafi-Ahmadi, Leila; Khademinia, Shahin. The article contains the following contents:

The present work described the one-pot multicomponent synthesis of heterocyclic 3,4-dihydropyrimidin-2-(1H)-ones I [R1 = H, 2-Cl, 4-OH, etc.; R2 = OMe, OEt; X = O] and thiones II [X = S] (DHPMs) under via Biginelli reaction of benzaldehydes, alkyl acetates, urea/thiourea under solvent-free conditions by Sr2As2O7 nanocatalyst. Sr2As2O7 nanocatalyst was synthesized by solvothermal reactions at stoichiometric molar ratio. The characterizations of the as-prepared nanomaterials were performed by X-ray powder diffraction (XRPD) and fourier-transform IR (FTIR) techniques. According to Rietveld anal. data, it was found that reaction time had a considerable effect on crystal phase change from monoclinic to tetragonal crystal system. Field emission scanning electron microscope (FESEM) images showed that the morphol. of the obtained materials was changed by increasing the reaction time, from 24 to 120 h, from long-length rods to multigonal plates. Langmuir-Hinshelwood kinetic model revealed that the reactions followed a pseudo-first order kinetic model.3-Hydroxybenzaldehyde(cas: 100-83-4Recommanded Product: 3-Hydroxybenzaldehyde) was used in this study.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Safari, Sahand’s team published research in Journal of Heterocyclic Chemistry in 2020 | CAS: 100-83-4

《Synthesis, biological evaluation and molecular docking study of dihydropyrimidine derivatives as potential anticancer agents》 was published in Journal of Heterocyclic Chemistry in 2020. These research results belong to Safari, Sahand; Ghavimi, Reza; Razzaghi-Asl, Nima; Sepehri, Saghi. Application of 100-83-4 The article mentions the following:

A series of dihydropyrimidine analogs I (R = H, 3-Cl, 2-OH, 4-NO2, etc.; R1 = Et, Ph; X = O, S) was prepared via one-pot Biginelli three-component condensation reaction. Subsequently, they were screened for in vitro anticancer effect. These analogs revealed good cytotoxic activity against three human cancer cell lines including MCF-7, HepG-2, and A549. Among these analogs, compounds I (R = H, R1 = Ph, X = S (A); R = 4-NO2, R1 = Ph, X = S (B)) were the most potent against three cell lines. Cell viability assays indicated that I (R = H, R1 = Ph, X = O; R = 2-OH, R1 = Ph, X = O) had lower cytotoxicity. In vitro cytotoxicity study on all synthesized compounds demonstrated that introduction of electron withdrawing substituents on C4 position of Ph ring of dihydropyrimidine contributed to the antiproliferative potency. Moreover, in silico mol. docking results stipulated a sign of good correlation between exptl. activity and calculated binding affinity. It proved (A) and (B) as the strongest compounds Binding modes of analogs proposed the involvement of hydrophobic interactions and hydrogen bonds with Eg5 active site. Structure activity relationship studies indicated that incorporating electron withdrawing substituents on C4 position of Ph ring of dihydropyrimidine are important for this biol. activity. After reading the article, we found that the author used 3-Hydroxybenzaldehyde(cas: 100-83-4Application of 100-83-4)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yaseen, Anaheed A.’s team published research in Polymers (Basel, Switzerland) in 2021 | CAS: 100-83-4

Yaseen, Anaheed A.; Al-Tikrity, Emaad T. B.; Yousif, Emad; Ahmed, Dina S.; Kariuki, Benson M.; El-Hiti, Gamal A. published their research in Polymers (Basel, Switzerland) in 2021. The article was titled 《Effect of Ultraviolet Irradiation on Polystyrene Containing Cephalexin Schiff Bases》.Reference of 3-Hydroxybenzaldehyde The article contains the following contents:

Synthesis and application of new UV photostabilizers for polystyrene and this research was focused on four cephalexin Schiff bases I [Ar = 3-OHC6H4, 4-BrC6H4, 4-OMeC6H4, 4-NMe2C6H4]. The reaction of cephalexin and 3-hydroxybenzaldehyde, 4-dimethylaminobenzaldehyde, 4-methoxybenzaldehyde, and 4-bromobanzaldehyde under acidic condition afforded the corresponding Schiff bases I in high yields. The Schiff bases were characterized and their surfaces were examined The Schiff bases were mixed with polystyrene to form homogenous blends and their effectiveness as photostabilizers was explored using different methods. The methods included monitoring the changes in the IR spectra, weight loss, depression in mol. weight, and surface morphol. on irradiation In the presence of the Schiff bases, the formation of carbonyl group fragments, weight loss, and decrease in mol. weight of polystyrene were lower when compared with pure polystyrene. In addition, undesirable changes in the surface such as the appearance of dark spots, cracks, and roughness were minimal for irradiated polystyrene containing cephalexin Schiff bases. Mechanisms by which cephalexin Schiff bases stabilize polystyrene against photodegradation was also suggested. The experimental part of the paper was very detailed, including the reaction process of 3-Hydroxybenzaldehyde(cas: 100-83-4Reference of 3-Hydroxybenzaldehyde)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ebrahimi, Mitra’s team published research in Journal of Heterocyclic Chemistry in 2020 | CAS: 100-83-4

《Ultrasonic accelerated efficient synthesis of aminobenzochromenes using Ag2Cr2O7 nanoparticles as a reusable heterogeneous catalyst》 was published in Journal of Heterocyclic Chemistry in 2020. These research results belong to Ebrahimi, Mitra; Abdolmohammadi, Shahrzad; Kia-Kojoori, Reza. Recommanded Product: 3-Hydroxybenzaldehyde The article mentions the following:

Ag2Cr2O7 nanoparticles were found to be an exceedingly effective catalyst for the mild and green synthesis of aminobenzochromenes I (R = H, 4-Br, 3-Cl, 4-CN, 3-OH, 3-NO2) and II. The reaction was performed under ultrasonic irradiation as an innocuous tool and in water as a green solvent at room temperature This method encompasses several sustainable and economic benefits. In the experiment, the researchers used 3-Hydroxybenzaldehyde(cas: 100-83-4Recommanded Product: 3-Hydroxybenzaldehyde)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ghafuri, Hossein’s team published research in Applied Organometallic Chemistry in 2020 | CAS: 100-83-4

《Copper-immobilized ionic liquid as an alternative to organic solvents in the one-pot synthesis of bioactive dihydropyrano[2,3-c]pyrazole derivatives》 was published in Applied Organometallic Chemistry in 2020. These research results belong to Ghafuri, Hossein; Kazemnezhad Leili, Maede; Esmaili Zand, Hamid Reza. Category: alcohols-buliding-blocks The article mentions the following:

In this study, a novel Cu-immobilized ionic liquid (IL) I · 3Cu(OAc)3- 3(H2O)was designed, characterized, and employed as both promoter and solvent in the synthesis of some dihydropyrano[2,3-c]pyrazoles II (R = C6H5, 2,4-(Cl)2C6H3, (CH2)2CH3, etc.; R1 = H, 4-O2NC6H4). The synthesized ionic liquid I · 3Cu(OAc)3- 3(H2O) was characterized by 1H NMR, 13C NMR, FTIR, ICP and EDX anal. and showed high catalytic activity to proceed the synthesis of bioactive dihydropyrano[2,3-c]pyrazole derivatives II. This method has the advantage of using the IL as a green medium for the synthesis of the products in high to excellent yields within short reaction times.3-Hydroxybenzaldehyde(cas: 100-83-4Category: alcohols-buliding-blocks) was used in this study.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Fischer, Klaus’s team published research in Journal of Chromatographic Science in 2021 | CAS: 100-83-4

Formula: C7H6O2In 2021 ,《RP-HPLC analysis of phenolic lignin monomers with DAD and coulometric array detection》 was published in Journal of Chromatographic Science. The article was written by Fischer, Klaus; Hoeffler, Susanne. The article contains the following contents:

An high performance liquid chromatog. (HPLC) method, applying diode array (DAD) and coulometric array detection simultaneously, was developed to determine monomeric phenolic compounds in lignin hydrolyzates. To allow for addnl. mass spectrometric detection, a formic acid gradient was designed as an alternative to the non-volatile phosphate buffer gradient. Within a total run time of 28 min, 10 out of 14 analytes were baseline separated by the formic acid gradient, and 8 compounds were completely resolved by the phosphate gradient. The dependence of the coulometric detection on cell potential, potential step width, eluent pH and eluent composition was comprehensively tested. Detection limits ≤20μg/L were achieved by DAD detection for nine analytes and by coulometric array detection for all analytes, demonstrating the superior sensitivity of electrochem. detection. DAD offered better linearity and reproducibility. Inter-day precision of peak heights spanned from 0.26 to 2.00% (formic acid gradient) and from 0.75 to 2.85% (phosphate buffer gradient) operating the DAD detector, but it exceeded 10% for several compounds applying the coulometric array detector. The simultaneous operation of both detectors offered an enhanced certainty of substance identification. The appropriateness of the method was confirmed by the anal. of various hydrolyzates of lignin-containing materials. The results came from multiple reactions, including the reaction of 3-Hydroxybenzaldehyde(cas: 100-83-4Formula: C7H6O2)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Harry, Nissy Ann’s team published research in Journal of Heterocyclic Chemistry in 2020 | CAS: 100-83-4

《A novel catalyst-free mechanochemical protocol for the synthesis of 2,3-dihydro-1H-perimidines》 was published in Journal of Heterocyclic Chemistry in 2020. These research results belong to Harry, Nissy Ann; Radhika, Sankaran; Neetha, Mohan; Anilkumar, Gopinathan. Computed Properties of C7H6O2 The article mentions the following:

A catalyst-free, and green grinding assisted method for the synthesis of 2,3-dihydro-1H-perimidines I [R = Et, Ph, 2-pyridyl, etc.] was developed. 1,8-Diaminonaphthalene and aldehydes were grounded using mortar and pestle for 5 min affording the product in moderate to excellent yields. The methodol. minimized the use of conventional workup and column chromatog. techniques. In the part of experimental materials, we found many familiar compounds, such as 3-Hydroxybenzaldehyde(cas: 100-83-4Computed Properties of C7H6O2)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nikoorazm, Mohsen’s team published research in Applied Organometallic Chemistry in 2020 | CAS: 100-83-4

《Copper and nickel immobilized on cytosine@MCM-41: as highly efficient, reusable and organic-inorganic hybrid nanocatalysts for the homoselective synthesis of tetrazoles and pyranopyrazoles》 was published in Applied Organometallic Chemistry in 2020. These research results belong to Nikoorazm, Mohsen; Tahmasbi, Bahman; Gholami, Shahab; Moradi, Parisa. Safety of 3-Hydroxybenzaldehyde The article mentions the following:

In this work, a green approach was reported for efficient synthesis of biol. active tetrazole and pyranopyrazole derivatives in the presence of Cu-Cytosine@MCM-41 and Ni-Cytosine@MCM-41 (copper (II) and nickel (II) catalyst on the modified MCM-41 using cytosine). The synthesis of tetrazoles and pyranopyrazoles in the presence of these catalysts was performed in green solvents such as water or poly (ethylene glycol) (PEG). All products were obtained in high TOF (turnover frequency) numbers in the presence of these catalysts, which indicate the high efficiency of these catalysts in the synthesis of tetrazole and pyranopyrazole derivatives The prepared catalysts were characterized by various techniques such as BET, TGA, XRD, FT-IR, SEM, EDS, WDX, TEM, and AAS. Mesoporous structure of these catalysts was confirmed by nitrogen adsorption-desorption isotherms. These catalysts can be recovered and reused for several runs without significant change in their catalytic activity or metal capacity. The recovered catalysts have been characterized by XRD, SEM, EDS, WDX, FT-IR and AAS techniques, by which their heterogeneous nature has been confirmed. In addition to this study using 3-Hydroxybenzaldehyde, there are many other studies that have used 3-Hydroxybenzaldehyde(cas: 100-83-4Safety of 3-Hydroxybenzaldehyde) was used in this study.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts