Category: 100-83-4

Ritmaleni; Hastutitama, A. N. A.; Persitamaia, I.; Restiwardani, T.; Eksakta, A.; Munandar, R. F.; Abdullah, M. S.; Purwanto, A. E.; Astuti, P.; Sardjiman published their research in Rasayan Journal of Chemistry in 2021. The article was titled 《Synthesis and antibacterial activity of dibenzylidene-cyclohexanone》.Safety of 3-Hydroxybenzaldehyde The article contains the following contents:

Dibenzylidene-cyclohexanones I (R = 3-O2NC6H4, 2-CH3OC6H4, 4-OH-3-CH3OC6H3, etc.) were synthesized by reacting aromatic aldehydes RCHO with cyclohexanone in the acidic condition through the carbonyl condensation reaction. The antibacterial activity was tested by using microdilution method against K. pneumonia, E. coli, S. aureus, B. subtilis and E. faecalis. The isolated products were obtained as pure curcumin analogs with moderate to high yield. The antibacterial assay showed that I (R = 3-OHC6H4) gave MIC and MBC at 50μg/mL in E. coli, S. aureus, and E. faecalis. Moreover, it showed that the percentage inhibition of B. subtilis was around 54% at a concentration of 25μg/mL. Among all the tested compounds, I (R = 3-OHC6H4) showed better activity against all those bacteria while none showed activity against K. pneumonia. A I (R = 2,5-CH3OC6H3) was obtained as the compound with the highest yield and I (R = 3-OHC6H4) was the most potent compound While I (R = 2-OH-3-C2H5OC6H3) was the most potent compound according to the docking study. In addition to this study using 3-Hydroxybenzaldehyde, there are many other studies that have used 3-Hydroxybenzaldehyde(cas: 100-83-4Safety of 3-Hydroxybenzaldehyde) was used in this study.

3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Safety of 3-Hydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Recommanded Product: 100-83-4In 2019 ,《SBA-15@Glycine-M (M= Ni and Cu): Two green, novel and efficient catalysts for the one-pot synthesis of 5-substituted tetrazole and polyhydroquinoline derivatives》 appeared in Solid State Sciences. The author of the article were Tamoradi, Taiebeh; Ghorbani-Choghamarani, Arash; Ghadermazi, Mohammad; Veisi, Hojat. The article conveys some information:

Two catalysts were prepared by the immobilization of Ni and Cu on ordered mesoporous silica (SBA-15) coated with glycine. The proposed catalysts were characterized by FT-IR, XRD, BET, TGA, EDX, and ICP-OES studies and were successfully applied in the synthesis of 5-substituted tetrazoles and polyhydroquinoline derivatives This designed protocol offered several advantages including the use of com. available and inexpensive materials, simple procedure, short reaction times, high yield, and easily separable and reusable catalyst. In addition to this study using 3-Hydroxybenzaldehyde, there are many other studies that have used 3-Hydroxybenzaldehyde(cas: 100-83-4Recommanded Product: 100-83-4) was used in this study.

3-Hydroxybenzaldehyde(cas: 100-83-4) is used as an ionophore, during the development of an highly selective and sensitive PVC membrane sensor, which can be used as a Tb3+ ion selective electrode.Recommanded Product: 100-83-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Product Details of 100-83-4In 2019 ,《Core-shell structured magnetic silica supported propylamine/molybdate complexes: an efficient and magnetically recoverable nanocatalyst》 was published in New Journal of Chemistry. The article was written by Neysi, Maryam; Zarnegaryan, Ali; Elhamifar, Dawood. The article contains the following contents:

In the present study, a novel core-shell structured magnetic silica supported propylamine/molybdate complex (Fe3O4@SiO2/Pr-N♂Mo[Mo5O18]) is prepared, characterized and applied as an effective and easily recoverable nanocatalyst. The chem. composition, crystalline structure, thermal stability, morphol. and particle size of this nanomaterial were studied using Fourier transform IR (FT-IR) spectroscopy, energy dispersive X-ray (EDX), transmission electron microscopy (TEM), powder X-ray diffraction (PXRD), SEM (SEM), thermal gravimetric (TG) and vibration sample magnetometer (VSM) analyses. This nanomaterial was used as an efficient and magnetically reusable catalyst for the synthesis of pyrano-pyrazole derivatives under moderate conditions and gave the corresponding products in high yield and selectivity. The results came from multiple reactions, including the reaction of 3-Hydroxybenzaldehyde(cas: 100-83-4Product Details of 100-83-4)

3-Hydroxybenzaldehyde(cas: 100-83-4) is used as an ionophore, during the development of an highly selective and sensitive PVC membrane sensor, which can be used as a Tb3+ ion selective electrode.Product Details of 100-83-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cadena-Cruz, Jose Eduardo; Guaman-Ortiz, Luis M.; Romero-Benavides, Juan Carlos; Bailon-Moscoso, Natalia; Murillo-Sotomayor, Kevin E.; Ortiz-Guaman, Nadia V.; Heredia-Moya, Jorge published their research in BMC Chemistry in 2021. The article was titled 《Synthesis of 4,4′-(arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ols) and evaluation of their antioxidant and anticancer activities》.SDS of cas: 100-83-4 The article contains the following contents:

The 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols) derivatives I (R = Ph, 3,4-dihydroxyphenyl, 2-nitrophenyl, etc.) were synthesized by a three-component reaction of 3-methyl-1-phenyl-5-pyrazolone with various benzaldehydes RCHO catalyzed by sodium acetate at room temperature The structures of all synthesized compounds were characterized by physicochem. properties and spectral means (IR and NMR) and evaluated for their radical scavenging activity by DPPH assay and tested in vitro on colorectal RKO carcinoma cells in order to determine their cytotoxic properties. All 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols) derivatives I were synthesized in high to excellent yield, and pure products were isolated by simple filtration. All compounds have good radical scavenging activity, and half of them are more active than ascorbic acid used as standard Several derivatives proved to be cytotoxic in the RKO cell line. In particular, compound I (R = 3,4-dihydroxyphenyl) proved to be a very potent scavenger with an IC50 of 6.2 ± 0.6μM and exhibited an IC50 of 9.9 ± 1.1μM against RKO cell. Autophagy proteins were activated as a survival mechanism, whereas the predominant pathway of death was p53-mediated apoptosis. The experimental process involved the reaction of 3-Hydroxybenzaldehyde(cas: 100-83-4SDS of cas: 100-83-4)

3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.SDS of cas: 100-83-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《A PANI-Fe3O4@ZnO nanocomposite: a magnetically separable and applicable catalyst for the synthesis of chromeno-pyrido[d]pyrimidine derivatives》 was published in RSC Advances in 2020. These research results belong to Chaghari-Farahani, Fatemeh; Abdolmohammadi, Shahrzad; Kia-Kojoori, Reza. Name: 3-Hydroxybenzaldehyde The article mentions the following:

Herein green, practical, PANI-Fe3O4@ZnO-nanocomposite-catalyzed cyclocondensation reactions involving 4-aminocoumarin, 1,3-dimethylbarbituric acid, and aromatic aldehydes in an aqueous medium at room temperature to synthesize 9,11-dimethyl-7-aryl-6H-chromeno[3′,4′:5,6]pyrido[2,3-d]pyrimidine-6,8,10(9H,11H)triones I (Ar = C6H5, 3-HOC6H4, 4-BrC6H4, etc.) is reported. This research aims to provide an applicable and high-yield protocol that follows the principles of green chem., with the use of water as an environmentally benign medium and the PANI-Fe3O4@ZnO nanocomposite as a magnetically recoverable catalyst. In the experimental materials used by the author, we found 3-Hydroxybenzaldehyde(cas: 100-83-4Name: 3-Hydroxybenzaldehyde)

3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Name: 3-Hydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Product Details of 100-83-4In 2019 ,《Covalent immobilization of Co complex on the surface of SBA-15: Green, novel and efficient catalyst for the oxidation of sulfides and synthesis of polyhydroquinoline derivatives in green condition》 was published in Polyhedron. The article was written by Ghorbani-Choghamarani, Arash; Mohammadi, Masoud; Tamoradi, Taiebeh; Ghadermazi, Mohammad. The article contains the following contents:

In this work, a green and novel catalyst was prepared through immobilization of cobalt complex on the surface of mesostructured SBA-15 and characterized by TGA, SEM, FT-IR, EDX, ICP, BET and X-ray mapping anal. methods. This mesostructural material was used as an efficient and green interphase catalyst for the oxidation reactions and synthesis of polyhydroquinoline derivatives All reactions were performed in short times and good yields. Moreover, the prepared catalyst could be used up to six runs without significant degradation in its catalytic activity or cobalt leaching. In the part of experimental materials, we found many familiar compounds, such as 3-Hydroxybenzaldehyde(cas: 100-83-4Product Details of 100-83-4)

3-Hydroxybenzaldehyde(cas: 100-83-4) is used as an ionophore, during the development of an highly selective and sensitive PVC membrane sensor, which can be used as a Tb3+ ion selective electrode.Product Details of 100-83-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Arabian Journal of Chemistry included an article by Maddila, S.; Abafe, O. A.; Bandaru, H. N.; Maddila, S. N.; Lavanya, P.; Seshadri, Nuthangi; Jonnalagadda, S. B.. Name: 3-Hydroxybenzaldehyde. The article was titled 《V-CaHAp as a recyclable catalyst for the green multicomponent synthesis of benzochromenes》. The information in the text is summarized as follows:

A simple and efficient one-pot method has been developed for the synthesis of benzochromenes I [R = 2-Cl, 4-CH3CH2, 2,5-(OCH3)2, etc.], using V-CaHAp as a heterogeneous catalyst by the condensation of aldehydes RC6H4CHO, β-naphthol and malononitrile in ethanol as solvent at room temperature for 20 min. The reaction, with this catalyst is carried out under mild reaction conditions with very good to excellent yields (89-98%). The material can be recycled very easily and reused for at least 6 runs without substantial loss in activity, which makes this methodol. environmentally benign. A feasible and cost-effective synthesis by using non-toxic materials and minimal catalyst, which is easy to handle has been achieved. In addition to this study using 3-Hydroxybenzaldehyde, there are many other studies that have used 3-Hydroxybenzaldehyde(cas: 100-83-4Name: 3-Hydroxybenzaldehyde) was used in this study.

3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Name: 3-Hydroxybenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

HPLC of Formula: 100-83-4In 2020 ,《New Copper Complex on Fe3O4 Nanoparticles as a Highly Efficient Reusable Nanocatalyst for Synthesis of Polyhydroquinolines in Water》 appeared in Catalysis Letters. The author of the article were Ashraf, Muhammad Aqeel; Liu, Zhenling; Peng, Wan-Xi; Gao, Caixia. The article conveys some information:

A simple, environmentally friendly and economical route for the preparation of a novel copper-Schiff-base organometallic complex on Fe3O4 nanoparticles (Fe3O4@Schiff-base-Cu) using an inexpensive and simple method and available materials is presented. This magnetic nanocatalyst was comprehensively characterized using Fourier transform IR spectroscopy (FT-IR), X-Ray Diffractometer (XRD), inductively coupled plasma at. emission spectroscopy (ICP), energy-dispersive X-ray spectroscopy (EDS), SEM (SEM), X-ray mapping, thermogravimetric anal. (TGA) and vibrating sample magnetometer (VSM) anal. In the second stage, the catalytic activity of this catalyst was studied in the synthesis of polyhydroquinoline derivatives I [R = Ph, 4-ClC6H4, 3,4-(HO)2C6H3, etc.] via Hantzsch reaction of aryl aldehydes RCHO, dimedone, Et acetoacetate and ammonium acetate in water as a green solvent. A simple preparation of the catalyst from the com. available materials, high catalytic activity, simple operation, short reaction times, high yields and use of green solvent can be regarded as advantages of this protocol. In addition, this nanocatalyst was easily recovered using external magnet and reused for several times without significant loss of its catalytic efficiency. Finally, the leaching, heterogeneity and stability of Fe3O4@Schiff-base-Cu were studied by hot filtration test and ICP technique. In addition to this study using 3-Hydroxybenzaldehyde, there are many other studies that have used 3-Hydroxybenzaldehyde(cas: 100-83-4HPLC of Formula: 100-83-4) was used in this study.

3-Hydroxybenzaldehyde(cas: 100-83-4) is used as an ionophore, during the development of an highly selective and sensitive PVC membrane sensor, which can be used as a Tb3+ ion selective electrode.HPLC of Formula: 100-83-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthetic Route of C7H6O2In 2021 ,《Design, synthesis and in silico screening of benzoxazole-thiazolidinone hybrids as potential inhibitors of SARS-CoV-2 proteases》 was published in RSC Advances. The article was written by Krishna Cheerala, Vijay Sai; Ghanta, Prasanth; Neelakantan, Sundaresan Chittor. The article contains the following contents:

Hybrid mols. in the recent years have gained significant importance in drug research as promising therapeutic agents. We report a novel combination of two such bioactive scaffolds (benzoxazole and 4-thiazolidinone B-T hybrids) as inhibitors of SARS-CoV-2. The study uses an in silico approach to identify the potential of B-T hybrids as possible inhibitors of the SARS-CoV-2 proteases. Mol. docking was employed to identify the interactions of B-T hybrids with the two proteases – 3CLp (the 3-chymotrypsin-like protease) and PLp (the papain-like protease). Docking results of the screened 81 hybrids indicated that BT10 and BT14 interacted with the catalytic dyad residue of 3CLp (Cys145) with the best binding energy. MD simulations revealed that BT10 formed stable interactions via 4 hydrogen bonds with the catalytic site residues of 3CLp. In the case of PLp, BT27 and MBT9 interacted with the catalytic triad residue of PLp (His272) with high binding energy. MD simulations demonstrated that the reference drug Tipranavir relocated to the thumb region of the protease whereas BT27 remained in the active site of PLp stabilized by 2 hydrogen bonds, while MBT9 relocated to the BL2 loop of the palm region. The MM-PBSA and interaction entropy (IE) anal. indicated that BT14 exhibited the best ΔG (of -6.83 kcal mol-1) with 3CLp, while BT27 exhibited the best ΔG (of -7.76 kcal mol-1) with PLp. A four-step synthetic procedure was employed to synthesize the B-T hybrids starting from ammonium thiocyanate. The short-listed compounds in the case of 3CLp were synthesized and characterized using IR, NMR, and HRMS spectroscopic techniques. The experimental process involved the reaction of 3-Hydroxybenzaldehyde(cas: 100-83-4Synthetic Route of C7H6O2)

3-Hydroxybenzaldehyde(cas: 100-83-4) is used as an ionophore, during the development of an highly selective and sensitive PVC membrane sensor, which can be used as a Tb3+ ion selective electrode.Synthetic Route of C7H6O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Current Organocatalysis included an article by Kasar, Sandeep B.; Thopate, Shankar R.. Category: alcohols-buliding-blocks. The article was titled 《Ultrasonically Assisted Efficient and Green Protocol for the Synthesis of 4H-isoxazol-5-ones using Itaconic Acid as a Homogeneous and Reusable Organocatalyst》. The information in the text is summarized as follows:

Itaconic acid was used as a green catalyst for the synthesis of 4H-isoxazol-5-ones derivatives under conventional as well as ultrasound irradiation technique. Ultrasound irradiation condition required less time for the completion of the reaction and also the yields were better. Ambient reaction conditions were used to carry out transformation for multicomponent reaction. Metal-free, mineral acid-free synthesis were key features of the present protocol. In the experiment, the researchers used many compounds, for example, 3-Hydroxybenzaldehyde(cas: 100-83-4Category: alcohols-buliding-blocks)

3-Hydroxybenzaldehyde(cas: 100-83-4) can be used as a reactant along with ethyl acetoacetate and thiourea in the synthesis of corresponding dihydropyrimidine-2-thione (monastrol), using Yb(OTf)3 as a catalyst by Biginelli cyclocondensation reaction.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts