Category: 100-55-0

《Microwave-heated γ-Alumina Applied to the Reduction of Aldehydes to Alcoholsã€?was published in ChemCatChem in 2020. These research results belong to Dhokale, Bhausaheb; Susarrey-Arce, Arturo; Pekkari, Anna; Runemark, August; Moth-Poulsen, Kasper; Langhammer, Christoph; Haerelind, Hanna; Busch, Michael; Vandichel, Matthias; Sunden, Henrik. Recommanded Product: 3-Pyridinemethanol The article mentions the following:

The development of cheap and robust heterogeneous catalysts for the Meerwein-Ponndorf-Verley (MPV) reduction is desirable due to the difficulties in product isolation and catalyst recovery associated with the traditional use of homogeneous catalysts for MPV. Microwave heated γ-Al2O3 which can be used for the reduction of aldehydes RCHO (R = CH2C6H5, 2-furyl, 4-pyridyl, etc.) to alcs. RCH2OH has been described. The reaction is efficient and has a broad substrates scope. The products can be isolated by simple filtration, and the catalyst can be regenerated. With the use of microwave heating, the heating can be directed to the catalyst rather than to the whole reaction medium. Furthermore, DFT was used to study the reaction mechanism, and it was conclude that a dual-site mechanism is operative where the aldehyde and 2-propoxide are situated on two adjacent Al sites during the reduction Addnl., volcano plots were used to rationalize the reactivity of Al2O3 in comparison to other metal oxides. In addition to this study using 3-Pyridinemethanol, there are many other studies that have used 3-Pyridinemethanol(cas: 100-55-0Recommanded Product: 3-Pyridinemethanol) was used in this study.

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Recommanded Product: 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,ChemistrySelect included an article by Choudhary, Anu; Sharma, Nitika; Sharma, Chandan; Jamwal, Babita; Paul, Satya. Application In Synthesis of 3-Pyridinemethanol. The article was titled 《Synergistic Effect of Cr3+ on Layered Double Hydroxide Supported Cu0 Nanoparticles for the Oxidation of Alcohols and Hydrocarbonsã€? The information in the text is summarized as follows:

Chromium(III)-doped layered double hydroxide supported copper nanoparticles (Cr3+-Cu0/LDH) has been prepared as an efficient and reusable catalyst using simple and versatile synthetic method. Effect of doping of Cr3+ to the layered double hydroxide supported Cu0 nanoparticles was evaluated for the oxidation of alcs. e.g., I and hydrocarbons e.g., II by varying the amount of Cr3+ loading in the catalyst. The catalyst with Cu:Cr ratio = 1:1 afforded highest catalytic activity among the synthesized catalysts towards the oxidation using TBHP (tBuOOH) in aqueous medium. The high activity and selectivity was assigned to the synergistic electronic interaction between copper(0) nanoparticles and chromium(III) ions based on exptl. data and XPS results. Moreover, the high stability of Cu0 and Cr3+ in the catalyst was attributed to the strong metal-support interactions, which make the catalyst recyclable upto five runs. In the experiment, the researchers used 3-Pyridinemethanol(cas: 100-55-0Application In Synthesis of 3-Pyridinemethanol)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Application In Synthesis of 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Green Chemistry included an article by Sun, Kang-kang; Sun, Jia-lin; Lu, Guo-Ping; Cai, Chun. Reference of 3-Pyridinemethanol. The article was titled 《Enhanced catalytic activity of cobalt nanoparticles encapsulated with an N-doped porous carbon shell derived from hollow ZIF-8 for efficient synthesis of nitriles from primary alcohols in waterã€? The information in the text is summarized as follows:

A cobalt catalyst derived from a unique core-shell structure based on hollow ZIF-8 and ZIF-67 (ZIF-67@ZIF-8) is prepared, which exhibits excellent catalytic efficiency for the synthesis of nitriles from alcs. in water under mild conditions (1 atm O2, 50°C) owing to its large BET surface area, high pore volume, high basicity and hydrophilicity.3-Pyridinemethanol(cas: 100-55-0Reference of 3-Pyridinemethanol) was used in this study.

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Reference of 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2022,Fernandes, Raquel A.; Sampaio, Maria J.; Faria, Joaquim L.; Silva, Claudia G. published an article in Molecules. The title of the article was 《Synthesis of Vitamin B3 through a Heterogeneous Photocatalytic Approach Using Metal-Free Carbon Nitride-Based Catalystsã€?SDS of cas: 100-55-0 The author mentioned the following in the article:

Vitamin B3 (nicotinic acid, VB3) was synthesized through the photocatalytic oxidation of 3-pyridinemethanol (3PM) under visible-light-emitting diode (LED) irradiation using metal-free graphitic carbon nitride (GCN) – based materials. A bulk (GCN) material was prepared by a simple thermal treatment using dicyandiamide as the precursor. A post-thermal treatment under static air and nitrogen flow was employed to obtain the GCN-T and GCN-T-N materials, resp. The conditions adopted during the post-treatment revealed differences in the resulting materials’ morphol., electronic, and optical properties. The post-treated photocatalysts revealed an enhanced efficiency in the oxidation of 3PM into VB3, with the GCN-T-N photocatalyst being the best-performing material. The defective surface, reduced crystallinity, and superior photoabsorption of GCN-T-N account for this material’s improved performance in the production of VB3. Nevertheless, the presence of nitrogen vacancies in the carbon nitride structure and, consequently, the creation of mid-gap states also accounts to its highly oxidative ability. The immobilization of GCN-T-N in sodium alginate hydrogel was revealed as a promising strategy to produce VB3, avoiding the need for the photocatalyst separation step. Concerning the mechanism of synthesis of VB3 through the photocatalytic oxidation of 3PM, it was possible to identify the presence of 3-pyridinecarboxaldehyde (3PC) as the intermediary product. In the experiment, the researchers used 3-Pyridinemethanol(cas: 100-55-0SDS of cas: 100-55-0)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.SDS of cas: 100-55-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of �-BocNH-ABNO-catalyzed aerobic oxidation of alcohol at room temperature and atmospheric pressure�were Zhao, Yajing; Li, Yutong; Shen, Zhenlu; Hu, Xinquan; Hu, Baoxiang; Jin, Liqun; Sun, Nan; Li, Meichao. And the article was published in Tetrahedron Letters in 2019. Category: alcohols-buliding-blocks The author mentioned the following in the article:

A transition-metal-free catalytic system has been developed for selective transformation of alc., e.g., 1,2,3,4-tetrahydronaphthalen-1-ol to aldehydes or ketones, e.g., 1,2,3,4-tetrahydronaphthalen-1-one. The reactions were performed with 3-(tert-butoxycarbonylamino)-9-azabicyclo[3.3.1]nonane N-oxyl (3-BocNH-ABNO) as the catalyst, NaNO2 as the co-catalyst, mol. oxygen as the terminal oxidant, and AcOH as the solvent under room temperature This catalytic system exhibited broad functional group tolerance. A series of alc. substrates, including primary and secondary benzylic alcs., heteroaromatic analogs, primary and secondary aliphatic alcs., could be converted into their corresponding aldehydes and ketones in good conversions and selectivities. In the experiment, the researchers used 3-Pyridinemethanol(cas: 100-55-0Category: alcohols-buliding-blocks)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cmâˆ?1 (ν19b mode) does not overlap with any of the other bands.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Maji, Milan; Borthakur, Ishani; Guria, Saikat; Singha, Suman; Kundu, Sabuj published their research in Journal of Catalysis in 2021. The article was titled 《Direct access to 2-(N-alkylamino)pyrimidines via ruthenium catalyzed tandem multicomponent annulation/N-alkylation》.Recommanded Product: 100-55-0 The article contains the following contents:

A new cooperative ruthenium complex catalyzed tandem multicomponent synthesis of 2-(N-alkylamino)pyrimidines I [R = Ph, 4-MeOC6H4; R1 = 4-MeC6H4, 4-BrC6H4, 2-thienyl, etc.; R2 = H, Me; R3 = Ph, 4-FC6H4, cyclohexyl, etc.; R2R3 = (CH2)5] directly from guanidine salt and alcs. was developed. The reactions proceeded through the dehydrogenation of alcs., followed by C-C coupling and sequential C-N coupling with guanidine and primary alc., with the elimination of three equivalent of hydrogen gas. In this work, application of both the acceptorless dehydrogenative coupling (ADC) and borrowing hydrogen (BH) strategies were accomplished in a single reaction. This catalytic method tolerated a wide range of substrates. The viability of the current method was demonstrated by preparative scale synthesis of a few products. A plausible catalytic cycle was proposed based on various control experiments, mechanistic studies and DFT calculations Remarkably, 42 new 2-(N-alkylamino)pyrimidines were synthesized following this catalytic protocol. The experimental part of the paper was very detailed, including the reaction process of 3-Pyridinemethanol(cas: 100-55-0Recommanded Product: 100-55-0)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Recommanded Product: 100-55-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Dalton Transactions included an article by Wang, Danfeng; McBurney, Roy T.; Pernik, Indrek; Messerle, Barbara A.. Application of 100-55-0. The article was titled 《Controlling the selectivity and efficiency of the hydrogen borrowing reaction by switching between rhodium and iridium catalysts》. The information in the text is summarized as follows:

The catalytic alkylation of ketones with alcs. via the hydrogen borrowing methodol. (HB) has the potential to be a highly efficient approach for forming new carbon-carbon bonds. However, this transformation can result in more than one product being formed. The work reported here utilizes bidentate triazole-carbene ligated iridium and rhodium complexes as catalysts for the selective formation of alkylated ketone or alc. products. Switching from an iridium center to a rhodium center in the complex resulted in significant changes in product selectivity. Other factors – base, base loading, solvent and reaction temperature – were also investigated to tune the selectivity further. The optimized conditions were used to demonstrate the scope of the reaction across 17 ketones and 14 alcs. containing a variety of functional groups. A series of mechanistic investigations were performed to probe the reasons behind the product selectivity, including kinetic and deuterium studies. In the experimental materials used by the author, we found 3-Pyridinemethanol(cas: 100-55-0Application of 100-55-0)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Application of 100-55-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Coufourier, Sebastien; Ndiaye, Daouda; Gaillard, Quentin Gaignard; Bettoni, Leo; Joly, Nicolas; Mbaye, Mbaye Diagne; Poater, Albert; Gaillard, Sylvain; Renaud, Jean-Luc published their research in Tetrahedron in 2021. The article was titled 《Iron-catalyzed chemoselective hydride transfer reactions》.SDS of cas: 100-55-0 The article contains the following contents:

A diaminocyclopentadienone iron tricarbonyl complex has been applied in chemoselective hydrogen transfer reductions This bifunctional iron complex demonstrated a broad applicability in mild conditions in various reactions, such as reduction of aldehydes over ketones, reductive alkylation of various functionalized amines with functionalized aldehydes and reduction of α,β-unsaturated ketones into the corresponding saturated ketones. A broad range of functionalized substrates has been isolated in excellent yields with this practical procedure. The experimental process involved the reaction of 3-Pyridinemethanol(cas: 100-55-0SDS of cas: 100-55-0)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.SDS of cas: 100-55-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cetinkaya, Sidika; Yurdakal, Sedat published an article in 2021. The article was titled 《Partial photocatalytic oxidations of 3-pyridinemethanol and 3-picoline by TiO2 prepared in HCl, HNO3 and H2SO4 at different temperatures》, and you may find the article in Catalysis Today.COA of Formula: C6H7NO The information in the text is summarized as follows:

Home prepared TiO2 photocatalysts were prepared from TiCl4 precursor in the absence and presence of HCl (1-6 M), HNO3 (1 M) or H2SO4 (1 M) at room temperature (RT), 60 or 100°C. The TiO2 catalysts were characterized by XRD, BET, SEM and TGA techniques. TiO2 catalyst could not form at low temperature (up to 60°C) in the presence of H2SO4. Just rutile phase was obtained for all TiO2 samples prepared at RT and 60°C in HCl or HNO3. At 100°C mainly both brookite and rutile phases were obtained in the presence of HCl or HNO3, while mainly anatase phase appeared in the presence of H2SO4. Nanorod structured TiO2 was formed in the presence of 1 M HCl or HNO3 at RT and 60°C. The prepared TiO2 catalysts were used for partial oxidation of 3-pyridinemethanol to 3-pyridinemethanal and vitamin B3 in water under UVA irradiation Moreover, photocatalytic oxidation of 3-picoline, precursor of 3-pyridinemethanol, was also performed, but much lower product selectivity values were obtained with respect to 3-pyridinemethanol oxidation However, selective 3-picoline oxidation could be performed at pH 2 with low activity. Degussa P25 was used for comparison and almost all home prepared catalysts showed a higher selectivity, but they showed to be less active than Degussa P25. The high selectivity of the home prepared samples was not due to the type of TiO2 phase, but mainly to the hydrophilicity of the TiO2 surface which allowed desorption of valuable products instead of their over-oxidation After reading the article, we found that the author used 3-Pyridinemethanol(cas: 100-55-0COA of Formula: C6H7NO)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. COA of Formula: C6H7NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2022,Ranjbar, Sara; Khoshneviszadeh, Mehdi; Tavakkoli, Marjan; Miri, Ramin; Edraki, Najmeh; Firuzi, Omidreza published an article in Molecular Diversity. The title of the article was 《5-Oxo-hexahydroquinoline and 5-oxo-tetrahydrocyclopentapyridine derivatives as promising antiproliferative agents with potential apoptosis-inducing capacity》.Electric Literature of C6H7NO The author mentioned the following in the article:

In this study, a series of 49 5-oxo-hexahydroquinoline and 5-oxo-tetrahydrocyclopentapyridines I [R1 = 3-pyridylmethyl, 2-pyridylethyl, 3-pyridylpropyl, etc.; R2 = Ph, 2-furanyl, Bu, etc.; X = (CH2)n; n = 1, 2], containing different pyridine alkyl carboxylates at C3 and various aliphatic, aromatic, and heteroaromatic substitutions at the C4 position of the central core, were synthesized. The target compounds I were tested for antiproliferative effect against three human cancer cell lines including MOLT-4 (acute lymphoblastic leukemia), K562 (chronic myelogenous leukemia), and MCF-7 (breast adenocarcinoma) by MTT assay, and the effect of the most potent derivatives on cell cycle was evaluated by RNase/propidium iodide (PI) flow cytometric assay. Generally, 5-oxo-hexahydroquinoline derivatives I [R1 = 3-pyridylpropyl; R2 = Ph, 2-furanyl, Bu, etc.; n = 2] possessed superior antiproliferative activities compared to their 5-oxo-tetrahydrocyclopentapyridine counterparts I [R1 = 3-pyridylpropyl; R2 = Ph, 2-furanyl, Bu, etc.; n = 1]. 5-Oxo-hexahydroquinoline compounds bearing 2-pyridyl Pr carboxylates I [R1 = 2-pyridylpropyl; R2 = Ph, 2-furanyl, Bu, etc.; n = 2] and 3-pyridyl Pr carboxylates I [R1 = 3-pyridylpropyl; R2 = Ph, 2-furanyl, Bu, etc.; n = 2] were better antiproliferative agents than those bearing other pyridyl alkyl carboxylates. Five best compounds with IC50 values in the range of 9.5-22.9μM against MOLT-4 cells were selected for cell-cycle anal., which revealed that derivatives I [R1 = 2-pyridylpropyl; R2 = 2,3-dichlorophenyl; n = 2], I [R1 = 3-pyridylpropyl; R2 = 3-nitrophenyl, 2-nitrophenyl; n = 2] with substitutions at C4 position, may induce apoptosis in MOLT-4 cells. Mol. docking anal., which was employed to make some predictions on the interaction of the most active derivatives with the binding site of Bcl-2 and Bcl-xL proteins, suggested that the compounds may be well accommodated within the binding sites of these anti-apoptotic proteins via hydrogen-bonding and hydrophobic interactions. The findings of this study present 5-oxo-hexahydroquinolines I [R1 = 3-pyridylmethyl, 2-pyridylethyl, 3-pyridylpropyl, etc.; R2 = Ph, 2-furanyl,butyl, etc.; n = 2]. as antiproliferative agents with potential apoptosis-inducing ability in cancer cells.3-Pyridinemethanol(cas: 100-55-0Electric Literature of C6H7NO) was used in this study.

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Electric Literature of C6H7NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts