Author: tianli

Nanocomplexes of Photolabile Polyelectrolyte and Upconversion Nanoparticles for Near-Infrared Light-Triggered Payload Release was written by Xiang, Jun;Ge, Feijie;Yu, Bing;Yan, Qiang;Shi, Feng;Zhao, Yue. And the article was included in ACS Applied Materials & Interfaces in 2018.Related Products of 60463-12-9 This article mentions the following:

A new approach to encapsulating charged cargo mols. into a nanovector and subsequently using near-IR (NIR) light to trigger the release is demonstrated. NIR light-responsive nanovector was prepared through electrostatic interaction-driven complexation between neg. charged silica-coated upconversion nanoparticles (UCNP@silica, 87 nm hydrodynamic diameter, polydispersity index ∼0.05) and a pos. charged UV-labile polyelectrolyte bearing pendants of poly(ethylene glycol) and o-nitrobenzyl side groups; whereas charged fluorescein (FLU) was loaded through a co-complexation process. By controlling the amount of polyelectrolyte, UCNP@silica can be covered by the polymer, whereas remaining dispersed in aqueous solution Under 980 nm laser excitation, UV light emitted by UCNP is absorbed by photolytic side groups within polyelectrolyte, which results in cleavage of o-nitrobenzyl groups and formation of carboxylic acid groups. Such NIR light-induced partial reversal of pos. charge to neg. charge on the polyelectrolyte layer disrupts the equilibrium among UCNP@silica, polyelectrolyte, and FLU and, consequently, leads to release of FLU mols. In the experiment, the researchers used many compounds, for example, 3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9Related Products of 60463-12-9).

3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Related Products of 60463-12-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Effect of carbon fiber and gamma irradiation on acrylonitrile butadiene styrene/high density polyethylene composites was written by Elnaggar, Mona Y.;Fathy, E. S.;Hassan, Medhat M.. And the article was included in Polymer Science, Series B: Polymer Chemistry in 2017.Formula: C16H26O7 This article mentions the following:

In this study, the effect of carbon fiber and gamma irradiation on acrylonitrile butadiene styrene (ABS)/high d. polyethylene matrix was investigated. The ternary composites with short carbon fiber of concentrations 15, 30, and 45 wt % were irradiated with doses of 100 and 300 kGy. In order to characterize the phys. and morphol. properties of all reinforced composites, wide X-ray diffraction, differential scanning calorimetry, thermo gravimetric anal., and SEM were performed. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Formula: C16H26O7).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Formula: C16H26O7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mono- and Dinuclear Coinage Metal Complexes Supported by an Imino-Pyridine-NHC Ligand: Structural and Photophysical Studies was written by Simler, Thomas;Moebius, Karen;Mueller, Kerstin;Feuerstein, Thomas J.;Gamer, Michael T.;Lebedkin, Sergei;Kappes, Manfred M.;Roesky, Peter W.. And the article was included in Organometallics in 2019.SDS of cas: 49669-14-9 This article mentions the following:

A new imino-pyridine-NHC (NHC = N-heterocyclic carbene) hybrid ligand was accessed through a multistep synthesis, and its coordination chem. was examined among coinage metals. Mononuclear copper, silver, and gold complexes as well as dinuclear homo- and heterometallic complexes were isolated and fully characterized by spectroscopic methods as well as x-ray crystallog. A comparative study of the structural and photophys. properties of the complexes was performed to get more insight into structure-property relationships. The photoluminescence (PL) properties were investigated in the solid state at temperatures between 20 and 295 K, and systematically compared with those of related complexes bearing a bipyridine-NHC ligand and previously reported by our group. The PL properties can be finely “tuned” depending on the coordinated metals, and the weak emission of the complexes can be traced back to the structural flexibility of the imino-pyridine-NHC framework. In the experiment, the researchers used many compounds, for example, 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9SDS of cas: 49669-14-9).

2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.SDS of cas: 49669-14-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Effects of dietary chenodeoxycholic acid supplementation in a low fishmeal diet on growth performance, lipid metabolism, autophagy and intestinal health of Pacific white shrimp, Litopenaeus vannamei was written by Li, Xiaoyue;Yao, Xinzhou;Zhang, Xinchen;Dong, Xiaohui;Chi, Shuyan;Tan, Beiping;Zhang, Shuang;Xie, Shiwei. And the article was included in Fish & Shellfish Immunology in 2022.Category: alcohols-buliding-blocks This article mentions the following:

An 8-wk feeding trial was conducted to evaluate the effects of chenodeoxycholic acid (CDCA) on growth performance, body composition, lipid metabolism, and intestinal health of juvenile white shrimp, Litopenaeus vannamei fed a low fishmeal diet. Four practical diets were formulated: HFM (25% fishmeal), LFM (15% fishmeal), LB1 (LFM + 0.04% CDCA), LB2 (LFM + 0.08% CDCA). Each diet was assigned to four tanks with forty shrimp (initial weight 0.33 ± 0.03 g) per tank. The results indicated that the growth performance of shrimp were similar between the four groups; the crude lipid content of shrimp fed the LB2 diet was significantly lower than those fed the HFM diet (P < 0.05). The lipase activity content in hepatopancreatic were significantly higher in the two CDCA supplemented groups than that in LFM group; the contents of total cholesterol, low-d. lipoprotein cholesterol, high-d. lipoprotein cholesterol in hemolymph were significantly lower in LFM group, LB1 group and LB2 group than that in HFM group (P < 0.05). The shrimp fed LB1 diet was significantly decreased the intestinal expression levels of tube than those fed in HFM diet; the intestinal gene expression of imd and toll were significantly lower in LB2 group than those in HFM group (P < 0.05). The results of hepatopancreas gene expression suggest that shrimp fed the LFM diet showed significantly upregulated expression levels of sterol regulatory element-binding protein (srebp), acetyl-CoA carboxylase (acc), and carnitine palmitoyltransferase 1 (cpt-1) than those fed the HFM diet; shrimp fed the LB1 diet showed significantly upregulated expression levels of srebp, acc, and AMP-activated protein kinase (ampk) than those fed the HFM diet; shrimp fed the LB2 diet had higher expression levels of srebp, acc, and cpt-1 than those fed the HFM diet (P < 0.05). In the hepatopancreas, the shrimp fed the LFM diet shown significantly up-regulated the expression levels of beclin1 compared to those fed HFM diet; the expression levels of autophagy-related protein13 (atg3), autophagy-related protein 12 (atg12) of in shrimp fed the LB1 diet were significantly higher than those fed the HFM diet; and the expression levels of autophagy-related protein13 (atg13), beclin1, atg3, atg12, autophagy-related protein 9 (atg9) of shrimp fed LB2 diet were significantly higher than those fed the HFM diet (P < 0.05). The atg3 in intestine of shrimp fed the LB2 diet were significantly higher than those fed the HFM diet (P < 0.05). Intestinal mucous fold were damaged, hepatic tubules were disorganized and B cells appeared to be swollen in LFM group. The fold height and width of shrimp fed the diets supplemented with CDCA increased significantly than those fed the LFM diet (P < 0.05), the hepatic tubules were neatly arranged, and R cells increased. In conclusion, supplementary CDCA in a low fishmeal diet promoted lipid metabolism, enhanced autophagy of shrimp, also improved the health of the intestine and hepatopancreas. In the experiment, the researchers used many compounds, for example, Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6Category: alcohols-buliding-blocks).

Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of functionalized helical BN-benzo[c]phenanthrenes was written by Abengozar, Alberto;Garcia-Garcia, Patricia;Sucunza, David;Perez-Redondo, Adrian;Vaquero, Juan J.. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2018.Application In Synthesis of (2-Bromo-5-chlorophenyl)methanol This article mentions the following:

A novel parent BN-benzo[c]phenanthrene, with helical chirality and remarkable structural features, has been easily obtained in three steps with a global yield of 55%. Moreover, Cl-substituted derivatives have been prepared and these have served as useful starting materials for the development of palladium-catalyzed cross-coupling reactions. In the experiment, the researchers used many compounds, for example, (2-Bromo-5-chlorophenyl)methanol (cas: 60666-70-8Application In Synthesis of (2-Bromo-5-chlorophenyl)methanol).

(2-Bromo-5-chlorophenyl)methanol (cas: 60666-70-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application In Synthesis of (2-Bromo-5-chlorophenyl)methanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Minimizing the interfacial resistance for a solid-state lithium battery running at room temperature was written by Wang, Qianchen;Ding, Xiangyu;Li, Jingbo;Jin, Haibo;Gao, Hongcai. And the article was included in Chemical Engineering Journal (Amsterdam, Netherlands) in 2022.Synthetic Route of C16H26O7 This article mentions the following:

A ceramic solid electrolyte of Li_1.5Al_0.5Ge_1.5(PO₄)₃ (LAGP) with high ionic conductivity (4.28 x 10^-4 S cm^-1 at 30 °C) and low activation energy (0.25 eV) is prepared by a three-step method, and the interfacial properties of the ceramic solid electrolyte are further modified by an in-situ polymerization strategy with the formation of a gel-polymer electrolyte with the thickness of 8.85 μm on the surface of LAGP. The presence of the gel-polymer electrolyte on the surface of LAGP inhibits the side reactions and the growth of lithium dendrites, as evidenced by the stable cycling of the lithium sym. cells with the modified LAGP solid electrolyte for 1000 h at 25 °C. In addition, the high ionic conductivity and the stable interface of the modified LAGP solid electrolyte enable the solid-state lithium battery with a LiFePO₄ cathode, exhibiting superior electrochem. performances which can run stably at 25 °C with initial discharge specific capacity of 159.8 mAh g^-1 at 0.1C. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Synthetic Route of C16H26O7).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Synthetic Route of C16H26O7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

para-Selective C-H Borylation of Aromatic Quaternary Ammonium and Phosphonium Salts was written by Lu, Shuo;Zheng, Tianyu;Ma, Jiawei;Deng, Zhangming;Qin, Shengmeng;Chen, Yu;Liang, Yong. And the article was included in Angewandte Chemie, International Edition in 2022.Name: 2-(Trifluoromethyl)phenethyl alcohol This article mentions the following:

Aromatic ammonium and phosphonium salts are important synthetic intermediates and multifunctional materials, but para-selective functionalization of the aromatic salts remains a challenge. Here authors developed ionic ligand based newly designed “biphenyl-phenanthroline” skeleton and realize the Ir-catalyzed para-selective C-H borylation of seven types of aromatic quaternary ammonium and phosphonium salts. Gram-scale transformation, late-stage elaboration for drug mol., and diversification of borylated products demonstrate the potential utility of this reaction. The mechanistic studies and computational anal. elucidate the origin of para-selectivity. In the experiment, the researchers used many compounds, for example, 2-(Trifluoromethyl)phenethyl alcohol (cas: 94022-96-5Name: 2-(Trifluoromethyl)phenethyl alcohol).

2-(Trifluoromethyl)phenethyl alcohol (cas: 94022-96-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Name: 2-(Trifluoromethyl)phenethyl alcohol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A Synthetic Approach to Dimetalated Arenes Using Flow Microreactors and the Switchable Application to Chemoselective Cross-Coupling Reactions was written by Ashikari, Yosuke;Kawaguchi, Tomoko;Mandai, Kyoko;Aizawa, Yoko;Nagaki, Aiichiro. And the article was included in Journal of the American Chemical Society in 2020.Name: 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane This article mentions the following:

In spite of their potential utility, the chem. of dimetallated arenes is still in its infancy because it is extremely difficult to synthesize them. Herein is reported a method of synthesizing arenes bearing a boryl group and a metallic substituent such as boryl, silyl, stannyl or zincyl group, based on generation and reactions of aryllithiums bearing a trialkyl borate moiety in a integrated flow microreactor. The bimetallic arenes showed a remarkable chemoselectivity in palladium-catalyzed cross-coupling reactions. The selectivity was switched by selection of the metal species constituting the dimetallated arenes together with appropriate catalysts. In the experiment, the researchers used many compounds, for example, 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4Name: 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane).

2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Name: 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cobalt-Catalyzed 1,1-Diboration of Terminal Alkynes: Scope, Mechanism, and Synthetic Applications was written by Krautwald, Simon;Bezdek, Mate J.;Chirik, Paul J.. And the article was included in Journal of the American Chemical Society in 2017.Name: 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine This article mentions the following:

A Co-catalyzed method for the 1,1-diboration of terminal alkynes with bis(pinacolato)diboron (B₂Pin₂) is described. The reaction proceeds efficiently at 23° with excellent 1,1-selectivity and broad functional group tolerance. With the unsym. diboron reagent PinB-BDan (Dan = naphthalene-1,8-diaminato), stereoselective 1,1-diboration provided products with two B substituents that exhibit differential reactivity. One example prepared by diboration of 1-octyne was crystallized, and its stereochem. established by x-ray crystallog. The utility and versatility of the 1,1-diborylalkene products was demonstrated in a number of synthetic applications, including a concise synthesis of the epilepsy medication tiagabine. A synthesis of 1,1,1-triborylalkanes was accomplished through Co-catalyzed hydroboration of 1,1-diborylalkenes with HBPin. D-labeling and stoichiometric experiments support a mechanism involving selective insertion of an alkynylboronate to a Co-B bond of a Co boryl complex to form a vinylcobalt intermediate. The latter was isolated and characterized by NMR spectroscopy and x-ray crystallog. A competition experiment established that the reaction involves formation of free alkynylboronate and the two boryl substituents are not necessarily derived from the same diboron source. In the experiment, the researchers used many compounds, for example, 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6Name: 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine).

2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Name: 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mechanochemical, Water-Assisted Asymmetric Transfer Hydrogenation of Ketones Using Ruthenium Catalyst was written by Kolcsar, Vanessza Judit;Szollosi, Gyorgy. And the article was included in ChemCatChem in 2022.Application In Synthesis of (R)-1-(3-Chlorophenyl)ethanol This article mentions the following:

The aim of this study was to develop a green system for the asym. transfer hydrogenation of ketones RC(O)R¹ (R = Ph, 2,6-difluorophenyl, 4-methoxyphenyl, phenylethyl, etc.; R¹ = Me) applying chiral Ru catalyst I in aqueous media and mechanochem. energy transmission. Using a ball mill, the milling parameters were optimized in the transfer hydrogenation of acetophenone followed by reduction of various substituted derivatives The scope of the method was extended to carbo- II (R² = H, 5-OMe, 7-Br, 6-CF₃, etc.; n = 1, 2, 3) and heterocyclic ketones III (R³ = H, 6-Cl, 8-Br; X = O, S, NH, N-BOC). The scale-up of the developed system was successful, and the optically enriched alcs. (R)-RC(OH)R¹, IV, V could be obtained in high yields. The developed mechanochem. system provides TOFs up to 168 h^-1. The present study is the first in which mechanochem. activated enantioselective transfer hydrogenations were carried out, thus, may be a useful guide for the practical synthesis of optically pure chiral secondary alcs. In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9Application In Synthesis of (R)-1-(3-Chlorophenyl)ethanol).

(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application In Synthesis of (R)-1-(3-Chlorophenyl)ethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts