Author: tianli

Occupational methacrylate and acrylate allergy – cross-reactions and possible screening allergens was written by Aalto-Korte, Kristiina;Henriks-Eckerman, Maj-Len;Kuuliala, Outi;Jolanki, Riitta. And the article was included in Contact Dermatitis in 2010.Computed Properties of C10H14O5 This article mentions the following:

Background: Acrylic resin monomers, especially acrylates and methacrylates, are important occupational allergens. Aims: To analyze patterns of concomitant patch test reactions to acrylic monomers in relation to exposure, and to suggest possible screening allergens. Patients/methods: We reviewed the patch test files for the years 1994-2009 at the Finnish Institute of Occupational Health for allergic reactions to acrylic monomers, and analyzed the clin. records of sensitized patients. Results: In a group of 66 patients allergic to an acrylic monomer, the most commonly pos. allergens were three methacrylates, namely ethyleneglycol dimethacrylate (EGDMA), 2-hydroxyethyl methacrylate (2-HEMA) and 2-hydroxypropyl methacrylate (2-HPMA), and an acrylate, namely diethyleneglycol diacrylate (DEGDA). The patterns of concomitant reactions imply that exposure to methacrylates may induce cross-reactivity to acrylates, whereas exposure to acrylates usually does not lead to cross-allergy to methacrylates. Screening for triethyleneglycol diacrylate (TREGDA) in the baseline series was found to be useful, as 3 of 8 patients with diagnosed occupational acrylate allergy might have been missed without the screening. Conclusions: A short screening series of four allergens, EGDMA, DEGDA, 2-HPMA and pentaerythritol triacrylate (PETA), would have screened 93% of our 66 patients: each of the remaining 5 patients reacted to different acrylic monomer(s). In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Computed Properties of C10H14O5).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Computed Properties of C10H14O5

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Untargeted metabolomics allows to discriminate raw camel milk, heated camel milk, and camel milk powder was written by Li, Rongrong;Wang, Shuang;Zhang, Jiawei;Miao, Jing;Chen, Gangliang;Dong, Jing;Wu, Linying;Yue, Haitao;Yang, Jie. And the article was included in International Dairy Journal in 2022.Formula: C4H10O4 This article mentions the following:

The metabolomic profiles of raw camel milk (RCM), heated camel milk (HCM) and camel milk powder (CMP) were analyzed by ultra-high-performance liquid chromatog. coupled with quadrupole time of flight mass spectrometer (UHPLC-Q-TOF/MS). One hundred and nineteen significantly changed metabolites with variable importance for the projection (VIP) > 1 (t-test p < 0.05) from the pos. mode were selected and identified in RCM, HCM and CMP. These metabolites included saccharides, glycosylamines, adenosines, and phospholipid. Among the saccharides, the content of D-lactose was the highest and slightly increased after thermal treatment. Dipeptides, including His-Pro and Lys-Trp, were significantly increased in HCM and CMP. As for glycosylamines, the content of N-acetylneuraminic acid was the highest. The amounts of larixinic acid increased dramatically in HCM and CMP (p < 0.001), which may improve the flavor of camel milk. In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6Formula: C4H10O4).

(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Formula: C4H10O4

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Metal-ligand stability constants of complexes of -hydroxyacetophenones with manganese and magnesium was written by Kamat, P. V.;Datar, M. G.. And the article was included in Journal of the Indian Chemical Society in 1970.Formula: C9H10O3 This article mentions the following:

Metal-ligand stability constants of complexes of substituted o-hydroxyaceto phenones with bivalent Mg and Mn were determined potentiometrically, at 30° a nd at an ionic strength of μ ∼ 0.1 M NaClO4, in non-aqueous media, 75 % dioxane-25% water (volume/volume). The nature and effect of substituents on the stability of the complexes is discussed. In the experiment, the researchers used many compounds, for example, 2′,6′-Dihydroxy-4′-methylacetophenone (cas: 1634-34-0Formula: C9H10O3).

2′,6′-Dihydroxy-4′-methylacetophenone (cas: 1634-34-0) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Formula: C9H10O3

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Nanoemulsion of Myrtus communis essential oil and evaluation of its larvicidal activity against Anopheles stephensi was written by Firooziyan, Samira;Osanloo, Mahmoud;Basseri, Hamid Reza;Moosa-Kazemi, Seyed Hasan;Mohammadzadeh Hajipirloo, Habib;Amani, Amir;Sedaghat, Mohammad Mehdi. And the article was included in Arabian Journal of Chemistry in 2022.Related Products of 499-75-2 This article mentions the following:

Excessive use of chem. insecticides has caused environmental pollution and vector resistance. Herbal essential oils with larvicidal properties are good alternatives to synthetic insecticides. In this study, larvicide properties of Myrtus communis essential oil and its nanoemulsion against Anopheles stephensi were investigated. Components of Myrtus communis essential oil were identified by GC-MS. Nanoemulsion of essential oil was made with Tween 80, Span 20, and water. Dynamic light scattering (DLS) and transmission electron microscopy (TEM) determined particle size and morphol. of nanoemulsions. The larvicide activity compared with bulk essential oil. A total of 107 M. communis essential oil compounds were discovered. The morphol. of a selected nanoemulsion was spherical. LC50 and LC90 of M. communis essential oil were calculated as 26.1 and 46.2 μg/mL, resp. The larvicide activity of nanoemulsion increased by 40% compared to the bulk essential oil. The nanoemulsion′s larvicide activity (100%) lasted up to 3 days, while the essential oil had larvicide properties only for up to 24 h. Myrtus communis essential oil was found to be an effective larvicide and classified as an active larvicide. The residual efficacy of the nanoformulation of M. communis significantly increased compared with the bulk essential oil. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Related Products of 499-75-2).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Related Products of 499-75-2

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Synthesis and Characterization of an Antibacterial Hydrogel Containing Covalently Bound Vancomycin was written by Lakes, Andrew L.;Peyyala, Rebecca;Ebersole, Jeffrey L.;Puleo, David. A.;Hilt, J. Zach;Dziubla, Thomas D.. And the article was included in Biomacromolecules in 2014.Name: Diethyleneglycoldiacrylate This article mentions the following:

The release of freely loaded small mols. from biomaterials often exhibits an initial burst, inhibiting the ability of these materials to match drug release with the biomaterial’s degradation period. In terms of antibiotic release systems, the remaining vehicle may become a substrate for colonization by bacterial biofilms once the payload is depleted, which can become life threatening. Secondary surgeries are typically performed to remove these empty depots as a means of preventing this type of infection. To maintain the effectiveness of a locally delivered antibiotic without the drawback of a second surgery, we propose a hydrogel drug delivery system in which the drug release rate of vancomycin and degradation rate of the hydrogel are linked via covalent incorporation of vancomycin in the hydrogel backbone. This was achieved through coupling PEG based monomer with vancomycin to create poly(β-amino ester) chem. and verified through drug release and matrix degradation studies. Antibiotic release and material degradation were tunable via hydrophobic/hydrophilic content of the hydrogel matrix and extended up to 3 wk in PBS sink conditions. Covalent addition of vancomycin to the hydrogel polymer backbone was verified through mass spectroscopy and HPLC peak addition, as well as radiotracing of collected HPLC fractions. Bioactivity of released vancomycin was also confirmed alongside the resulting antimicrobial activity of the reacted vancomycin releasate. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Name: Diethyleneglycoldiacrylate).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Name: Diethyleneglycoldiacrylate

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Novel thioether Schiff base transition metal complexes: Design, synthesis, characterization, molecular docking, computational, biological and catalytic studies was written by Singh, Anmol;Gogoi, Himadri Priya;Barman, Pranjit;Guha, Ankur Kanti. And the article was included in Applied Organometallic Chemistry in 2022.Category: alcohols-buliding-blocks This article mentions the following:

A series of novel copper(II), nickel(II), zinc(II) and cobalt(II) Schiff base metal complexes were synthesized by the reaction of 2-(benzylthio)aniline with pyrrole-2-carboxaldehyde and characterized by FT-IR, UV-visible, elemental analyses, ¹H-NMR, magnetic susceptibility and ESI-MS. The Schiff base ligand posed as an NS-bidentate ligand, confirming the synthesis of metal complexes with the suggested structure, according to the spectrum anal. data. All the complexes acquire square planar geometry. Furthermore, the DFT method was utilized to conduct computational analyses of metal complexes. The spectroscopic (UV-Vis and fluorescence) techniques were employed to probe the binding nature of calf thymus-DNA binding to metal complexes. The metal complexes interact with DNA through intercalative mode, according to the spectroscopic titration data. The antioxidant properties of metal complexes were evaluated using their reducing ability and free radical scavenging activity of DPPH. The antioxidant property is high in isolated complexes. The in vitro anti-inflammatory efficacy of all complexes has also been studied. All the metal complexes exhibited effective anti-inflammatory activity and can be used as synthetic drugs. The synthesized copper(II) complex exhibits excellent catalytic activities for the transformation reaction of alc. to aldehyde in the presence of hydrogen peroxide. The interaction of metal complexes with active sites of the B-DNA (1-BNA) and 6-COX (COX 2) was studied using docking studies. In the experiment, the researchers used many compounds, for example, (4-Chlorophenyl)methanol (cas: 873-76-7Category: alcohols-buliding-blocks).

(4-Chlorophenyl)methanol (cas: 873-76-7) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Category: alcohols-buliding-blocks

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Cobalt-catalyzed alkoxycarbonylation of ethers: Direct synthesis of α-oxy esters from phenols and alcohols was written by Wang, Le-Cheng;Xu, Jian-Xing;Wu, Xiao-Feng. And the article was included in Journal of Catalysis in 2022.Formula: C10H20O This article mentions the following:

A cobalt-catalyzed direct alkoxycarbonylation of ethers (such as THF, 1,4-dioxane, ethoxyethane, etc.) has been accomplished. This new catalytic system allows the use of ethers, important building blocks in organic synthesis, as the carbonylation substrates. A variety of phenols and alcs. ROH was transformed to the corresponding α-oxy ester derivatives ROC(O)R¹ (R¹ = oxolan-2-yl, 1,4-dioxan-2-yl, 1-ethoxyethyl, etc.; R = Ph, naphthalen-2-yl, pyridin-3-yl, adamantan-1-yl, etc.) in high yields with excellent functional group tolerance. In addition, several pharmaceutical and bioactive mol. related compounds were also suitable substrates for this carbonylation process, and the target products were obtained in good yields. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Formula: C10H20O).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Formula: C10H20O

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A nutritional strategy to promote gilthead seabream performance under low temperatures was written by Teodosio, Rita;Aragao, Claudia;Colen, Rita;Carrilho, Raquel;Dias, Jorge;Engrola, Sofia. And the article was included in Aquaculture in 2021.COA of Formula: C18H32CaN2O10 This article mentions the following:

Gilthead seabream (Sparus aurata) is vulnerable to low water temperature, which may occur in the Southern Europe and Mediterranean region during Winter. Fish are poikilothermic animals, therefore feed intake, digestion, metabolism and ultimately growth are affected by water temperature This study aimed to evaluate growth performance, feed utilization, nutrient apparent digestibility, and nitrogen losses to the environment in gilthead seabream juveniles reared under low temperature (∼13 °C). Three isolipid and isoenergetic diets were formulated: a diet similar to a com. feed (COM) that contained 44% crude protein and 27.5% fishmeal, and two exptl. diets with a lower protein content of 42% (ECO and ECOSup). In both ECO diets fishmeal inclusion was reduced (10% in ECO and 7.5% in ECOSup diet) and 15% poultry meal was included. Addnl., the ECOSup diet was supplemented with a mix of feed additives intended to promote fish growth performance and feed intake. The ECO diets presented lower production costs than the COM diet, while incorporating more sustainable ingredients. Gilthead seabream juveniles (±154.5 g initial body weight) were randomly assigned to triplicate tanks and fed the diets for 84 days. Fish fed the ECOSup diet attained a similar final body weight than fish fed the COM diet, significantly higher than fish fed the ECO diet. ECOSup fed fish presented significantly higher hepatosomatic index than COM fed fish, most likely due to higher hepatic glycogen reserves. The viscerosomatic index of ECOSup fed fish were significantly lower compared to COM fed fish, which is a pos. achievement from a consumer′s point of view. ECOSup diet exhibited similar nutrient digestibility than the COM diet. Moreover, feeding fish with the ECO diets resulted in lower faecal nitrogen losses when compared to COM fed fish. The results suggest that feeding gilthead seabream with an eco-friendly diet with a mix of feed additives such as the ECOSup diet, promoted growth and minimised nitrogen losses to the environment. Nutritional strategies that ultimately promote feed intake and diet utilization are valuable tools that may help conditioning fish to sustain growth even under low temperatures In the experiment, the researchers used many compounds, for example, Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6COA of Formula: C18H32CaN2O10).

Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.COA of Formula: C18H32CaN2O10

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Catalytic activity of SBA-15 supported CuO for selective oxidation of veratryl alcohol to veratraldehyde was written by Dhinagaran, G.;Harichandran, G.;Suvaitha, S. Prashanna;Venkatachalam, K.. And the article was included in Molecular Catalysis in 2022.SDS of cas: 57-55-6 This article mentions the following:

Selective oxidation of veratryl alc. (VAlc) to veratraldehyde (VAld) under mild conditions using heterogeneous catalysts is advantageous for industrial applications. In the present study, newly developed SBA-15 supported copper oxide catalyst designated as CuO(5,10,15 weight%)/SBA-15 was examined for the selective oxidation of VAlc to VAld using tert-Bu hydroperoxide (TBHP) as an oxidant between 40 and 100°C. CuO(10 weight%)/SBA-15 showed high conversion (82.5%) compared to others by forming VAld with 100% selectivity. We examined its selective oxidising power using a substrate possessing both the primary and secondary alc. functions, namely propylene glycol (PG). In this substrate, only the secondary alc. group was oxidized to hydroxyacetone (HA). It suggests preferential adsorption of the primary alc. group of PG on the catalyst surface close to the adsorbed TBHP, thus leaving only the secondary alc. group positionally favorable for oxidation In addition, the catalyst effectively oxidized 2-butanol to 2-butanone. So, the catalyst is verified active against both primary and secondary alcs., but when both of them are present on the adjacent carbons of the same compound, only the secondary alc. function is oxidized. So, the present catalyst could have tremendous applications for selective oxidation in organic synthesis. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6SDS of cas: 57-55-6).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.SDS of cas: 57-55-6

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Nonlinear optical organic co-crystals of merocyanine dyes and phenolic derivatives with short hydrogen bonds was written by Bosshard, Christian;Pan, Feng;Wong, Man Shing;Manetta, Sabine;Spreiter, Rolf;Cai, Chengzhi;Gunter, Peter;Gramlich, Volker. And the article was included in Chemical Physics in 1999.HPLC of Formula: 60463-12-9 This article mentions the following:

We investigated the co-crystallization of merocyanine dyes M (M : RN⁺C₅H₄CH:CHC₆H₄O^–, M1: R = Me, M2: R = HOCH₂CH₂) with phenolic and aniline derivatives and show that the short or very short hydrogen bond between the two phenolic oxygen atoms which lead to a self-assembly of the M dyes and phenol derivatives is the key steering force for the cocrystn. process. The cocrystal formation was studied by m.p. determination, by second-harmonic generation using the Kurtz and Perry powder test, and X-ray structural anal. We present detailed results on the growth, polymorphism, and nonlinear optical properties of cocrystals of derivatives of M1 (M2) and m-nitrophenol (mNP) and cocrystals of M2 and Me 2,4-dihydroxybenzoate (MDB). Three phases of the cocrystal M2·mNP and three phases of the cocrystal M2·MDB were found. Both M2·MDB(I) and (II) have the same crystal structure (space group symmetry Cc determined by X-ray diffraction), but show different linear and nonlinear optical properties. This unusual property in the co-crystals of M2·MDB(I) and (II) may be caused by a different proton location of the short hydrogen bond (O-H-O) in the aggregation between M2 and MDB which could not be resolved by X-ray diffraction. In the experiment, the researchers used many compounds, for example, 3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9HPLC of Formula: 60463-12-9).

3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.HPLC of Formula: 60463-12-9

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