Xu, Qi; Zhou, Xiaoxuan; Zhang, Si; Pan, Ling; Liu, Qun; Li, Yifei published the artcile< Visible-Light-Induced Sulfur-Alkenylation of Alkenes>, Application In Synthesis of 627-27-0, the main research area is dialkyl butenedithiol preparation diastereoselective regioselective; alkene ketene dithioacetal sulfur alkenylation trimethylphenylacridinium perchlorate photoredox catalyst.
A visible-light-induced intermol. sulfur-alkenylation of alkenes RCH=CR1R2 (R = H, Me, ethyl; R1 = H, Me, ethyl; R2 = Et, Ph, 2-naphthyl, acetyloxy, etc.; R1R2 = -(CH2)4-, -(CH2)5-; RR2 = -(CH2)3-, -(CH2)4-, -(CH2)2CH=CH-, etc.), 6,6-dimethyl-2-methylene-bicyclo[3.1.1]heptane including both activated and unactivated alkenes, mols. even induced by sunlight under ambient conditions is described. This sulfur-alkenylation reaction proceed in a highly regio- and stereospecific manner involving the visible-light-induced conversion of a ketene dithioacetal to the thiavinyl 1,3-dipole intermediate, followed by a formal [3+2] cycloaddition and C-S bond cleavage. Furthermore, it is also an efficient approach for the late-stage functionalization of natural products and complex mols., even being induced by sunlight under ambient conditions.
Organic Letters published new progress about [3+2] Cycloaddition reaction catalysts (stereo-, regioselective). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Application In Synthesis of 627-27-0.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts