Hu, Qiang; Yu, Wan-Lei; Luo, Yong-Chun; Hu, Xiu-Qin; Xu, Peng-Fei published the artcile< A Photosensitizer-Free Radical Cascade for Synthesizing CF3-Containing Polycyclic Quinazolinones with Visible Light>, Product Details of C4H8O, the main research area is trifluoroethyl pyrroloquinazolinone preparation; alkenyl cyanobenzamide trifluoroacetic anhydride tandem photocyclization; trifluoromethyl spiro cycloalkane pyrroloquinazolinone preparation; cycloalkenyl cyanobenzamide trifluoroacetic anhydride tandem photocyclization.
An efficient photoinduced radical tandem trifluoromethylation/cyclization reaction of N-cyanamide alkenes for the synthesis of functionalized quinazolinones was reported. Importantly, the reaction was carried out under mild conditions without any addnl. photosensitizer, metal or extra additives. A series of trifluoromethyl quinazolinones were prepared efficiently with good yields and excellent functional group tolerance. Preliminary mechanism experiments were conducted to indicate that the transformation proceeded via a possible mechanism involving photoexcited EDA complex and chain propagation.
Journal of Organic Chemistry published new progress about Alkenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Product Details of C4H8O.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts