Li, Jian-Yuan; Huang, Hongbing published the artcile< Development of DNA-Compatible Suzuki-Miyaura Reaction in Aqueous Media>, SDS of cas: 660867-80-1, the main research area is DNA Suzuki Miyaura reaction aryl halide boronic acid.
DNA-encoded chem. libraries (DELs) are a cost-effective technol. for the discovery of novel chem. probes and drug candidates. A major limiting factor in assembling productive DELs is the availability of DNA-compatible chem. reactions in aqueous media. In an effort to increase the chem. accessibility and structural diversity of small mols. displayed by DELs, the authors developed a robust Suzuki-Miyaura reaction protocol that is compatible with the DNA structures. By employing a water-soluble Pd-precatalyst, the authors developed conditions that allow efficient coupling of DNA-linked aryl halides with a wide variety of boronic acids/esters including heteroaryl boronates.
Bioconjugate Chemistry published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent) (DNA-conjugate). 660867-80-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H18BNO2, SDS of cas: 660867-80-1.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts