Yao, Zhengdong; Feng, Huangdi; Xi, Hui; Xi, Chuanjun; Liu, Weiping published the artcile< CF3SO3H-enabled cascade ring-opening/dearomatization of indole derivatives to polycyclic heterocycles>, Category: alcohols-buliding-blocks, the main research area is fused polycyclic indoline amine preparation; indole trifluoromethanesulfonic acid cascade ring opening dearomatization.
A novel dearomatization process to produce fused polycyclic indolines via a CF3SO3H-mediated cascade ring-opening of a β-lactam and hydroaminative cyclization is demonstrated. It provides a new strategy for the synthesis of important polycyclic indoline-2-amine derivatives in moderate to excellent yields, as well as with good functional group tolerance. Moreover, transformation of the product was performed to deliver the corresponding acid, alc. and amide smoothly.
Organic & Biomolecular Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Category: alcohols-buliding-blocks.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts