Fischer, Oliver; Heinrich, Markus R. published the artcile< 2-Fluoro-5-nitrophenyldiazonium: A Novel Sanger-Type Reagent for the Versatile Functionalization of Alcohols>, Category: alcohols-buliding-blocks, the main research area is aryl alkoxy nitrobenzenediazonium tetrafluoroborate preparation; alc fluoro nitrophenyldiazonium tetrafluoroborate nucleophilic aromatic substitution; C−C bond formation; C−H activation; Sanger reagent; diazonium; nucleophilic aromatic substitution.
As a novel Sanger-type reagent, 2-fluoro-5-nitrophenyldiazonium tetrafluoroborate enabled the versatile functionalization of primary aliphatic alcs. e.g., β-citronellol and secondary aliphatic alcs. e.g., trans-1,2-cyclohexandiol. Based on a mild nucleophilic aromatic substitution of the fluorine atom under unprecedented, base-free conditions, the diazonium unit on the aromatic core of the resulting aryl-alkyl ether e.g., I could be employed for such diverse transformations as radical C-H activation and cyclization, as well as palladium catalyzed cross-coupling reactions.
Chemistry – A European Journal published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Category: alcohols-buliding-blocks.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts