Huang, Qi-Ping; Jia, Jia; Li, Wei-Piao; Wang, An-Jun; Zhao, Liang published the artcile< Atom transfer radical additions (ATRAs) promoted by catalytic amounts of amines: the effective iododifluoroalkylation of alkenes/alkynes>, Safety of But-3-en-1-ol, the main research area is alkene alkyne iodination difluoroalkylation regioselective dimethylpiperazine catalyst.
Recently, fluoroalkylation reactions initiated via noncovalent interaction (halogen bond or EDA complexes) have become an attractive method to access fluoro-containing compounds, and most of those reactions were promoted by visible light and stoichiometric electron-donor compounds Here, a novel atom transfer radical addition (ATRA) reaction promoted by catalytic amount of 1,4-dimethylpiperazine on heating has been developed. This protocol enables a simple and practical alternative for the effective iododifluoroalkylation of alkenes or alkynes, which features synthetic simplicity, wide substrate scope and feasibility of product transformations.
Synthetic Communications published new progress about Alkynes, aryl Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Safety of But-3-en-1-ol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts